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The Clinical Experience of Pineal Parenchymal Tumors
박관웅,김정훈,김창진,나영신,이정교 대한신경외과학회 2004 Journal of Korean neurosurgical society Vol.36 No.2
Objective : Pineal parenchymal tumors (PPT) are rare; therefore, only limited clinical data regarding their behavior is available. The aim of this study is to evaluate the pathologic features, clinical behavior, and response to therapy of these tumors. Methods : Thirteen patients with biopsy-proven PPT were treated from September 1992 to February 2004 in our hospital. Their medical records and radiologic studies were analyzed retrospectively. The tumors were divided into three groups : pineocytoma, pineoblastoma, and mixed pineocytoma-pineoblastoma or PPT with intermediate differentiation. Initial stages were made by spinal magnetic resonance images and cerebrospinal fluid cytology. Magnetic resonance images were used for defining the treatment response of the patients. Results : The patients were divided into 4 pineocytomas, 5 pineoblastomas, and 4 mixed/intermediate PPT. The patients aged from 2 to 77 years. The patients presented with headache, nausea, vomiting, memory and gait disturbances, and impaired vision. Only one patient showed disseminated disease at initial staging. All patients that had surgery showed improvements of hydrocephalus. Two patients showed complete responses to treatment, six showed partial responses, two showed stable diseases, and two showed disease progression. Eleven patients were alive, but two were dead due to disease progression. Conclusion : Obtaining a tissue diagnosis in patients with PPT is important. Although our experience is limited, we consider that multimodality therapies including surgical resection, radiotherapy, chemotherapy, and radiosurgery must be considered for better outcome in treating patients with PPT. More experience is necessary to determine the optimal treatments of PPT.
Neurotoxic Manifestations of an Overdose Intrathecal Injection of Gadopentetate Dimeglumine
박관웅,임수빈,김범태,황선철,박종선,신원한 대한의학회 2010 Journal of Korean medical science Vol.25 No.3
The intravenous administration of gadopentetate dimeglumine (GD) is relatively safe and rarely causes systemic toxicity in the course of routine imaging studies. However,the general safety of intrathecal GD has not been established. We report a very rare case of an overdose intrathecal GD injection presenting with neurotoxic manifestations, including a decreased level of consciousness, global aphasia, rigidity,and visual disturbance.
Vertebra Plana Caused by a Giant Cell Tumor: A Case Report and Literature Review
차장규,신원한,박관웅,김희경,박재성,이혜경 대한영상의학회 2010 대한영상의학회지 Vol.62 No.6
We report here on the case of a 19-year-old woman who presented with progressive weakness of the lower extremities. The radiographs and CT showed vertebra plana of the first thoracic vertebral body. The mass had low signal intensity on the T1-weighted MR image and intermediate signal intensity on the T2-weighted MR image, and this low signal intensity extended to the spinal canal. Histological examination revealed a giant cell tumor (GCT). MR imaging is the imaging modality of choice for helping to distinguish spinal GCT from other spinal tumors by defining the extent and characteristic signal intensity of the tumor.
한국산 낭피버섯속(Cystoderma)의 분류학적 연구
반승언,김광상,김경제,김현석,진성우,박관웅,조덕현 한국버섯학회 2008 한국버섯학회지 Vol.6 No.2
Cystoderma list of the species found in Korea is composed of 6 species(Lee & Lee 2000). Cystoderma in Korea is Cystoderma amiaanthinum, Cystoderma carcharias, Cystoderma fallax, Cystoderma granulosum, Cystoderma japonicum and Cystoderma terreii. As the member of Lepiotaceae, Cystoderma belongs under Eumycotina, Basidiomycotina, Eubasidimycotina, Hymenomycetidiae, and Agaricales. Its outer pileus of Cystoderma is serrate radially, a small scale is scattered its peridium. And stipe has a small annulus attached to it. spores is subspore or fusiform, white and it has pseudoamyloid. Each shape, size, shine and quility of fruiting body of Cystoderma is different in the breed and it is important sources of a classification of Cystoderma. Especially, the shapes and colors of various scaly which are on the surface of the fungus are important to the external classification.
삼나무(Cryptomeria japonica) 목재와 지엽(枝條)이 큰느타리버섯(Pleurotus eryngii)의 자실체 발생에 미치는 영향
김현석,김광상,김경제,반승언,진성우,박관웅,채정기 한국버섯학회 2008 한국버섯학회지 Vol.6 No.2
This study was conducted to research the effect of Cryptomeria japonica sawdust and branch on the Production of Fruiting body of Pleurotus eryngii. Quantity of fruit body was lower in 5.2things/ bottle but yield of fruit body was higher in 3.5things/ bottle about big fruit body than Douglas-fir sawdust medium on C. japonica sawdust medium, so yield of fruit body was more 45g than Duglas-fir sawdust medium. But in the C. japonica branch sawdust medium, both quantity of fruit body and yield of fruit body was remarkably lower 13.3things/bottle, 42.8g/bottle respectively than Duglas-fir sawdust medium.