비디오 흉강경을 이용한 자연성 기흉 수술

류지윤,김승우,조광현,Ryu, Ji-Yun,Kim, Seung-U,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1997 Journal of Chest Surgery (J Chest Surg) Vol.30 No.5

자연성 기흉은 흉부외과 영역에서 흔히 접하게되는 질환으로 대부분의 경우 폐쇄식 흉강삽관술로 잘 치료 되지만 높은 재발율과 지속적인 공기누출로 인한 폐의 팽창부전등의 이유로 개흉술을 시행해야 하는 경우가 많다. 이러한 경우 개흉술로 인한 수술후 통증, 창상감염, 큰 절개흉터등의 문제가 남게되는데 이러한 문제를 해결하는데 효과적인 비디오 흉강경 수술이 현재 각광을 받고 있다. 본 인제대학교 부산백병원 흉부외과학 교실에서는 최근 3년간 자연성 기흉 환자 66명에 대해 비디오 흉강 경을 이용한 수술을 시행하여 다음과 같은 결과를 얻었다. 남녀 비는 63:3으로 남자가 절대적으로 많았으며 연령별로는 10대후반이 36명으로 전체의 55%를 차지하였다. 발생부위는 우측이 30례, 좌측이 36례 였으며 내원시 임상증상은 흉통, 호흡곤란, 흉부 불쾌감 순이였다. 수술적응증으로는 재발성이 36례로 대부분을 차지하였고 기흉 발생후 흉부 X-선상에서 기포가 보인 경우가 15례 였으며 흉관 삽관후 지속적인 공기 누출로 폐 팽창이 않된 경우가 10례였으며, 환자 본인이 수술을 원 하였던 경우가 5례였다. 기포를 포함한 폐부분 절제술을 시행한 경우\ulcorner 2례였고 폐부분 절제술과 더불어 늑막유착술을 동시에 시 행한 경우가 59례로 대부분을 차지하였다. 명백하게 폐기포를 발견할 수 없었던 5례에서는 늑막유착술만을 시행하였다 슬후 합병증은 4례에서 재발성 기흉이 발생하였고 무기폐와 폐렴 Ifl, 투관침 삽관부위 출혈이 1례 발생하였으나 모두 적절한 치료로 해결되었다. 흉강경을 이용한 자연성 기흉 수술은 여러 가지 장점이 많은 효과적인 수술방법으로 사료되어지며 기타 다른 흉부질환에 있어서도 그 적응증이 더욱 늘어나고 앞으로 더욱 발전될 전망이다. We have experienced 66 cases of video assisted thoracic surgery(VATS) of spontaneous pneumothorax. The patients ranged in age from 1 Syears to 46years(mean age, 22.3years) and male patients were sixty three. The indications of video assisted thoracic surgery of spontaneous pneumothorax were recurrence, continuous air leakage, visible blabs on the chest X-ray & others. Infraoperative findings were as follows; blabs, pleural adhesion and pleural effusion. The operation was performed under general anesthesia wit double lumen endobronchial tube. Operative procedures included blebectomy and/or wedge resection of lung, vibramycin Pleurodesis with mechanical abrasion. In most cases, postoperative courses were uneventful and patients were discharged without significant complications. VATS provided the benefits of lesser postoperative pain, rapid recovery, short hospitalization, and smaller scar of wound. Conclusively VATS is a new interesting modality of surgical treatment of spontaneous pneumothorax and also can be extensively applicable in the diagnosis and treatment of other intrathoracic disease.

개심술시 혈청 $\beta_2$-microglobulin 의 변동에 관한 연구

류지윤,조광현,Ryu, Ji-Yun,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1989 Journal of Chest Surgery (J Chest Surg) Vol.22 No.2

Nowadays, in spite of the remarkable development of the results of open heart surgery, the incidence of postoperative acute renal failure [ARF] has been increased due to the expansion of the candidates and prolonged operation time for complicated cases. It is also well known that ARF after open heart surgery, if once occurred, is a critical complication, therefore early diagnosis and treatment about it are very important for prognosis. Recently a low molecular weight [2 * microglobulin [[2* MG]has been used as a indicator of renal function. Because of the properties of [2 * MG, serum concentration of it is increased in glomerular dysfunction and urine excretion of it is increased in tubular dysfunction. Author studied about the perioperative changes of serum [2* MG and BUN concentration in 25 children and 30 adults for evaluation of significances of [2* MG as a parameter of postoperative renal function in open heart surgery, and the results were obtained as follows. l. In open heart surgery, the serum [2* MG concentration was elevated postoperatively in the all cases from the first postoperative day. 2. There were a significant correlation between the preoperative BUN and [2* MG concentration [P< 0.01]. The correlation factor[r] in child group was 0.8512, and in adults 0.8636. 3. The maximum level of serum [2* MG in the both child and adult groups were noticed in 4th postoperative day as 2.61*0.80mg/ 1 in child group and 3.39*1.47 mg/ 4 in adult group, and there was a significant difference between the two groups statistically[P < 0.05]. 4. The pattern of changes of serum concentration of [2* MG with time was very similar with the changes of BUN, but in a case of ARF [expired with it] the changes of [2* MG was more remarkable. 5. There was a significant differences in the maximum level of [2* MG between the 2 group according to the ECC time [groups of below and above 60 minutes] [P< 0.01].

흉곽출구 증후군 수술 치험 1례

류지윤,강인득,조광현,Ryu, Ji-Yun,Gang, In-Deuk,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1988 Journal of Chest Surgery (J Chest Surg) Vol.21 No.3

Thoracic outlet syndrome refers to compression of the subclavian vessels and brachial plexus at the superior aperture of the thorax. it was previously designated according to presumable etiologies such as scalenus anticus, costoclavicular, hyperabduction, cervical rib and first thoracic rib syndromes. We experienced a case of thoracic outlet syndrome[costoclavicular syndrome] which was caused by posttraumatic left clavicular fracture. Patient had suffered from swelling and cyanosis of left forearm and hand. preoperative vascular doppler test, angiography and venography were performed. First rib resection was done with transaxillary approach. After operation preoperative cyanosis and swelling of left forearm and hand were disappeared. Postoperative course was uneventful.

대동맥류의 수술적 치료에 관한 임상적 연구

류지윤,전홍주,조광현,Ryu, Ji-Yun,Jeon, Hong-Ju,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1997 Journal of Chest Surgery (J Chest Surg) Vol.30 No.3

We have experienced 25 cases of aortic aneurysm from October 1987 to January 1996. Patients ranged in age from 26yrs to 73yrs(mean age 52. Syrs). There were 13 males and 12 females. Eighteen cases were thoracic aneurysm and seven were abdom nal aneurysm. The cause of aneurysm were dissecting in 16cases aneurysms and non-dissecting in 9 cases. Risk factors of aortic aneurysm were hypertension, hypercholesterolemia, Marfan's syndrome. In thoracic aneurysm patients, 1'S cases of dissecting aneurysm underwent aneurysmectomy and replacement of vessel interposition graft with or without coronary artery implantation on the graft. 6 cases of non-dissecting aneurysm underwent operation with same policy as dissecting aneurysm. In 7 case of abdominal aneurysm,all patients underwent aneurysmectomy and graft interposition with straight i)r Y graft. Thcre were 5 postoperative death(mortality 20%). Several cases of complications were improved with proper managements. All survivors showed improvement in clinical symptom and sign and discharged without specific complications. 인제대학교 부속 부산백병 원 흉부외과학교실에서는 지난 87년 10월부터 96년 1월까지 총25례의 흉부 및 복부 대동맥류를 수술로 치험하였다. 환자의 연령은 최소 26세에서 최고 73세(평균연령 52. 5세)였으며 남자가 13명 여자가 12명이였다. 발생 부위에 따라흉부 대동맥류가 18례 복부 대동맥류가7례였다. 원인에 따른 분류에서 16례가 박리성이 였으며 9례가 비박리성 대동맥류였다. 동맥류의 위험 인자로는 고혈압이 가장 많았으며 기타 고지질증, Marfan증후군등이였다. 흉부 대동맥류는 침범 부위에 따라 동맥류 절제술과 인조혈관 대치술 및 관상동맥 이식술등을 증례에 따라적절히 시행하였다. 복부 대동맥류는 동맥류 절제후 침범 부위에 따라 일자 또는 역Y형 인조혈관 을 대 치시켰다. 총 5례의 술후 사망이 있어서 수술 사망률은 20%였으며 생존 환자는 특별한 합병증 없이 퇴원하였다.

식도의 평활근종 수술치험 1

류지윤,우종수,조광현,Ryu, Ji-Yun,U, Jong-Su,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1987 Journal of Chest Surgery (J Chest Surg) Vol.20 No.1

We experienced a case of esophageal leiomyoma recently in department of Thoracic and Cardiovascular Surg., Pusan Baik Hospital, Inje Medical College. Patient had suffered from dysphagia and chest discomfort for 2 years. The esophagogram showed an ovoid smooth filling defect in lower portion of the esophagus, mucosal fold of esophagus was not destroyed. A benign intramural tumor of the esophagus such as leiomyoma was suspected with X-ray finding and clinical features. Open thoracotomy was performed through the left 8th intercostal space. A firm egg sized mass in the well of lower esophagus was enucleated by blunt dissection with caution to avoid injury of the mucosa of the esophagus. The diagnosis of leiomyoma was confirmed with histopathological finding. Postoperative course was uneventful.

진핵세포에서 HSV-1 Envelope 변이 단백질의 발현 및 발현 단백질의 특성 연구

류지윤,박진서,Ryu, Ji-Yoon,Park, Jin-Seu 대한미생물학회 1999 Journal of Bacteriology and Virology Vol.29 No.3

Human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein is synthesized as a 160 KDa precursor, gp160, that is cleaved by a cellular protease to form the gp120 and gp41 subunits. Mammalian expression vectors were designed that are capable of efficient expression of various mutant envelope glycoproteins derived from a molecular clone of HIV-1. To construct these vectors, one type of mutation was made at the gp120-gp41 cleavage site by oligonucleotide-directed mutagenesis. And another mutation was made to change amino acids in the membrane spanning region of HIV-1 gp41 important for membrane anchorage. Next, these two mutations were combined to generate a vector to have double mutations in cleavage site and membrane-spanning region. These mutants were transiently expressed in mammalian cells. The effect of these mutations on envelope glycoprotein synthesis, proteolytic processing and secretion was determined. In addition, cell surface expression and ability of the glycoprotein to induce syncytium formation were examined. This study provides a mammalian expression system that is capable of efficient expression and secretion of soluble gp160.

형질세포 육아종 1례 치험 보고

류지윤,우종수,조광현,Ryu, Ji-Yun,U, Jong-Su,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1987 Journal of Chest Surgery (J Chest Surg) Vol.20 No.4

Plasma cell granuloma of the lung is very rare and most commonly detected in routine chest films. The prognosis of this disease is usually good with surgical resection. Recently, we experienced a case of this, the diagnosis of which was confirmed by postoperative histopathological examination. The operation was right upper lobectomy under the impression of benign tumor of the lung. The postoperative course was uneventful and the patients was discharged without any complication. Now we report this with literature reviews.

750kW Gearless형 풍력발전시스템 국산화 개발

류지윤(Ryu, Ji-Yun),김두훈(Kim, Du-Hun),박진일(Park, Jin-Il),황진수(Hwang, Jin-Su),변철진(Byeon, Cheol-Jin),김대현(Kim, Dae-Hyeon),방조혁(Bang, Jo-Hyeok),장성태(Jang, Seong-Tae),정진화(Jeong, Jin-Hwa),전중환(Jeon, Jung-Hwan),김동언(K 한국신재생에너지학회 2005 한국신재생에너지학회 학술대회논문집 Vol.2005 No.11

본 연구는 2001년 12월부터 2004년 12월까지 정부지원으로 유니슨(주)가 개발을 주관하고 포항공과대학교 및 국내 관련 기업이 참여한 콘소시엄에서 개발한 750kW Gearless형 풍력발전시스템의 국산화 개발에 관한 연구결과로서 풍력발전 시스템의 하중평가, 구성요소품의 설계 결과와 블레이드, 발전기 및 전력변환장치 등 개발요소품의 성능시험결과와 국제 설계인증 추진 및 시제품 제작에 대한 내용을 포함하고 있다.

도수 소생기와 풍선을 이용한 공기 누적이 폐 기능에 미치는 즉각적인 효과 비교

류지윤 ( Ji-yun Ryu ),이동엽 ( Dong-yeop Lee ),홍지헌 ( Ji-heon Hong ),김진섭 ( Jin-seop Kim ),김성길 ( Seong-gil Kim ) 대한통합의학회 2021 대한통합의학회지 Vol.9 No.1

Purpose : To compare the immediate effects of air stacking maneuver using resuscitator bags and balloons. Methods : Twenty healthy young adults participated in this study. Forced vital capacity (FVC) and peak cough flow (PCF) tests were performed at pre-intervention, and then, the maximum insufflation capacity (MIC), forced expiratory volume in 1 s (FEV₁), FEV₁/FVC, peak expiratory flow (PEF), and peak cough flow (PCF) were measured using the air stacking maneuver via resuscitator bags and balloons. Interventions were randomly performed, and a 40-min break was provided between interventions. The evaluation process in this study was conducted in accordance with the guidelines of the American Thoracic Society (ATS) 2019. To compare the three outcomes measured at pre-and post-interventions, repeated measures analysis of variance was performed. Results : A significant difference was found in the MIC, FEV₁, PEF, and PCF after the air stacking maneuver using resuscitator bags and balloons, whereas no significant difference was observed between resuscitator bags and balloons. Conclusion : No significant difference was found in the immediate effect of the air stacking maneuver using resuscitator bags and balloons in this study. Air stacking maneuver using balloons can increase the success rate of the techniques by providing visual feedback on the amount of air insufflation when performed with balloon blowing exercise. Balloons are cheaper and easier to buy compared to manual resuscitator bags; therefore, education on the air stacking maneuver using balloons will have a positive effect on pulmonary rehabilitation.

유니슨 2MW 풍력발전 시스템 소개

류지윤(J. Y. Ryu),김상덕(S. D. Kim),박선호(S. H. Park) 유공압건설기계학회 2011 드라이브·컨트롤 Vol.8 No.1