풍력발전의 국내$\cdot$외 기술개발 현황과 향후 전망

류지윤 환경보전협회 2005 환경정보 Vol.- No.355

Clagett 수술로 치료한 만성 농흉 치험 1례

류지윤 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.2

42 - year - old male patient was hospitalized with chest pain and dyspnea. He had a past history of right pleural effusion 6years ago and was managed with closed thoracotomy and after then he had been in well, 2day before admission chest pain and dyspnea were developed and aggravated on admission day. He visited our emergency room and closed thoracotomy was done and 1100㏄ pus was drained. After closed thoracomy was done, chest pain and dyspnea were remained. Chest CT showed chronic empyema of right chest. Explorothoracomy with decortication was done(1st Operation) and followed two emergency operations due to massive postoperative bleeding. After final operation dead space was remained and patient was discharged with Heimlich valve pneumobag. During OPD follow-up, MRSA infection of pleural cavity was found. Patient was readmitted and pleural space irrigation was done with povidone mixed saline daily. After pleural space cleaned up, remained pleural space was filled with antibiotics mixed saline solution(Clagett's Operation). After operation, patient condition was much improved and discharged without andy events.

심내막상 결손증 술후 추적 관찰에 관한 연구

류지윤 대한흉부심장혈관외과학회 1994 Journal of Chest Surgery (J Chest Surg) Vol.27 No.3

Endocardial cushion defect is a rare congenital heart disease. From September 1985, we experienced 20 cases of endocardial cushion defects and postoperative follow up was taken.We reviewed preoperative clinical data, echocardiography, cardiac cath data, operative method & time. After operation, we performed echocardiography and examined mitral valve function & integrity of patch closure sites. Postoperative follow up was taken regularly & follow up period was from 2 month to 91 months. Several postoperative complications were overcome with adequate treatment. There were 3 cases of early death and mortality rate was 15% [3/20].

식도의 평활근종 수술치험 1

류지윤,우종수,조광현,Ryu, Ji-Yun,U, Jong-Su,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1987 Journal of Chest Surgery (J Chest Surg) Vol.20 No.1

We experienced a case of esophageal leiomyoma recently in department of Thoracic and Cardiovascular Surg., Pusan Baik Hospital, Inje Medical College. Patient had suffered from dysphagia and chest discomfort for 2 years. The esophagogram showed an ovoid smooth filling defect in lower portion of the esophagus, mucosal fold of esophagus was not destroyed. A benign intramural tumor of the esophagus such as leiomyoma was suspected with X-ray finding and clinical features. Open thoracotomy was performed through the left 8th intercostal space. A firm egg sized mass in the well of lower esophagus was enucleated by blunt dissection with caution to avoid injury of the mucosa of the esophagus. The diagnosis of leiomyoma was confirmed with histopathological finding. Postoperative course was uneventful.

六味地黃湯 및 八味地黃湯이 抗改良型 馬杉腎炎에 미치는 影響

柳志允 圓光大學校大學院 1983 學位論叢 Vol.10 No.-

The curative effectiveness of Yukmijiwhangtang and Palmijiwhangtand for kidney disease has been widely known in oriental medicine. Their effectiveness in clinical therapy was investigated in this paper. This study was to investigate the anti-nephritic effects of the treatments of Yukmijiwhangtang and Palmijiwhangtang on the modified Masugi's nephritis. With the modified model of Masugi's nephritis in rat, the antinephritic effects of Yukmijiwhangtang and Palmijiwhangtang were evaluated by determing the biochemical parameters in urine, serum and renal cortex as well as by light microscopic observation in kidneys. After manafacturing the anti-rat kidney serum, it was given to the subjects in order to bring about nephritics. The results of this study were as follows: 1. The level of protein in urine was reduced significantly on 30th day after treatment of Yukmijiwhangtang. 2. THe level of protein in urine was reduced significantly on 10th day after treatment of Palmijiwhangtang. 3. The activity levels of AIP and LDH were reduced but not significant. 4. The levels of choresterol and triglyceride in serum of nephritic rats with the treatment of Palmijiwhangtang were reduced significantly on 30th day after treatment. The level of BUN was not significant. 5. Histological examination using a light microscope showed a significant recovery of glomerular lesions of nephritic rats treated with Palmijiwhangtang.

형질세포 육아종 1례 치험 보고

류지윤,우종수,조광현,Ryu, Ji-Yun,U, Jong-Su,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1987 Journal of Chest Surgery (J Chest Surg) Vol.20 No.4

Plasma cell granuloma of the lung is very rare and most commonly detected in routine chest films. The prognosis of this disease is usually good with surgical resection. Recently, we experienced a case of this, the diagnosis of which was confirmed by postoperative histopathological examination. The operation was right upper lobectomy under the impression of benign tumor of the lung. The postoperative course was uneventful and the patients was discharged without any complication. Now we report this with literature reviews.

Clinical Analysis of Spontaneous Pneumomediastinum

류지윤 대한결핵및호흡기학회 2012 Tuberculosis and Respiratory Diseases Vol.73 No.3

Background: Spontaneous pneumomediastinum is a rare and benign condition that generally occurs in young generations without any precipitating factor or underlying disease. The purpose of this study is to review our experience in dealing with this entity and detail a reasonable course of assessment and management. Methods: From December 1999 to May 2012, 32 spontaneous pneumomediastinum patients were managed in our hospital. We retrospectively reviewed the result of management. Results: Patients ranged in age from 10 to 38 years, with the mean age of 18.3±5.6 years. Twenty-five patients were men and seven were women. Initial WBC count was 10,039±2,993/μL and thirty-one patients underwent computed tomography. Twenty-two patients underwent esophagography and results were shown to be normal. Twenty-five patients were admitted in the hospital and the mean duration of admission was 3.4±2.0 days. All patients were managed conservatively and discharged without any complications. Conclusion: Spontaneous pneumomediastinum is a benign condition combined with mild inflammatory signs and secondary causes must to excluded to avoid unfavorable outcomes and select proper management modality. Background: Spontaneous pneumomediastinum is a rare and benign condition that generally occurs in young generations without any precipitating factor or underlying disease. The purpose of this study is to review our experience in dealing with this entity and detail a reasonable course of assessment and management. Methods: From December 1999 to May 2012, 32 spontaneous pneumomediastinum patients were managed in our hospital. We retrospectively reviewed the result of management. Results: Patients ranged in age from 10 to 38 years, with the mean age of 18.3±5.6 years. Twenty-five patients were men and seven were women. Initial WBC count was 10,039±2,993/μL and thirty-one patients underwent computed tomography. Twenty-two patients underwent esophagography and results were shown to be normal. Twenty-five patients were admitted in the hospital and the mean duration of admission was 3.4±2.0 days. All patients were managed conservatively and discharged without any complications. Conclusion: Spontaneous pneumomediastinum is a benign condition combined with mild inflammatory signs and secondary causes must to excluded to avoid unfavorable outcomes and select proper management modality.

開心術 時 血淸 β₂-microglobulin의 變動에 關한 硏究

柳智允 인제대학교 1989 仁濟醫學 Vol.10 No.2

오늘날 개심수술의 성적은 현저히 진보되었다고 할 수 있는 반면, 개심술 후 신장기능 부전증의 발생률은 심장수술 대상자의 확대와 어려운 장시간의 수술 등으로 인하여 오히려 증가된 상태에 있다고 하겠다. 신부전이란 일단 발생하게 되면 환자의 예후를 크게 좌우하기 때문에 신부전의 조기 진단과 치료는 환자의 예후에 매우 중요하다. Berggard가 밝힌 저분자 단백인 β2-MG(분자량 11,800)가 최근 신 기능의 지표로써 응용되고 있는데, 혈중 β2-MG는 쉽게 신 사구체 기저막을 통과하여 세뇨관에서 거의 모두 재흡수되어 세뇨관상피에서 대사 분리된다. 따라서 사구체 기능 장해가 있으면 혈중 β2-MG의 농도가 증가될 것이며, 재흡수 장해가 있으면 뇨중 β2-MG의 배설량이 증가된다는 사실에 바탕을 두고 있다. 개심술에 의한 신 기능의 변화를 예상하는데 도움이 되는지의 여부를 검토하기 위하여 저자는 소아 및 성인 개심술 환자 55명에서 혈중 β2-MG치의 수술 전후 변동을 추적하여 다음과 같은 결과를 얻었다. 1.開心術 全例에서 수술 후 제 1일째부터 혈청β2-MG치의 상승이 있었다. 2.수술 전 BUN치와 β2-MG치의 상관관계를 검토해본 결과 소아군(N=25)에서는 상관계수(r)가 0.8512, 성인군(N=30)에서는 상관계수(r)가 0.8636으로 양군 모두 매우 유의한(p<0.001) 正常關 관계를 보여주었다. 3.소아군과 성인군 모두 술후 4일째 β2-MG치는 각기 2.61±0.88mg/l, 3.39±1.47mg/l로 최대치에 도달하려는데, 양군간에 의미있는 차(p<0.05)가 있었고, 술후 7일째 양군 모두 술전치에 접근하였다. 4.소아 및 성인 양군 모두에서 BUN치의 시간적 변동과 β2-MG치의 시간적 변동이 유사한 변화를 하였으나 신 기능 부전으로 사망한 1례에서는 β2-MG치의 변동이 보다 예민하였다. 5.체외순환 60분 미만군(N=24)과 60분 이상군(N=31) 상호간에 술후 β2-MG 최대치에 유의한 차(p<0.01)가 있었다. Nowadays, inspite of the remarkable development of the results of open heart surgery, the incidence of postoperative acute renal failure (ARF) has been increased due to the expansion of the candidates and prolonged operation time for complicated cases. It is also well known that ARF after open heart surgery, if once occurred, is a critical complication, therefore early diagnosis and treatment about it are very important for prognosis. Recently a low molecular weight β2-microglobulin (β2-MG) has been used as a indicator of renal function. Because of the properties of β2-MG, serum concentration of it is increased in glomerular dysfunction and urine excretion of it is increased in tubular dysfunction. Author studied about the perioperative changes of serum β2-MG and BUN concentration in 25 children and 30 adults for evaluation of the significances of β2-MG as a parameter of postoperative renal function in open heart surgery, and the results were obtained as follows. 1.In open heart surgery the serum β2-MG concentration was elevated postoperatively in the all cases from the first postoperative day. 2.There were a significant correlation between the preoperative BUN and β2-MG concentration (p< 0.01). The correlation factor (r) in child group was 0.8512, and in adults 0.8636, 3.The maximum level of serum β2-MG in the both child and adult groups were noticed in 4th. postoperative day as 2.61 ±0.80 mg/l in child group and 3.39±1.47 mg/l in adult group, and there was a significant difference between the two groups statistically (p<0.05). 4.The pattern of changes of serum concentration of β2-MG with time was very similar with the changes of BUN, but in a case of ARF (expired with it) the changes of β2-MG was more remarkable. 5.There was a significant differences in the maximum level of β2-MG between the 2 groups according to the ECC time (groups of below and above 60 minutes) (p<0.01).

개심술시 혈청 $\beta_2$-microglobulin 의 변동에 관한 연구

류지윤,조광현,Ryu, Ji-Yun,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1989 Journal of Chest Surgery (J Chest Surg) Vol.22 No.2

Nowadays, in spite of the remarkable development of the results of open heart surgery, the incidence of postoperative acute renal failure [ARF] has been increased due to the expansion of the candidates and prolonged operation time for complicated cases. It is also well known that ARF after open heart surgery, if once occurred, is a critical complication, therefore early diagnosis and treatment about it are very important for prognosis. Recently a low molecular weight [2 * microglobulin [[2* MG]has been used as a indicator of renal function. Because of the properties of [2 * MG, serum concentration of it is increased in glomerular dysfunction and urine excretion of it is increased in tubular dysfunction. Author studied about the perioperative changes of serum [2* MG and BUN concentration in 25 children and 30 adults for evaluation of significances of [2* MG as a parameter of postoperative renal function in open heart surgery, and the results were obtained as follows. l. In open heart surgery, the serum [2* MG concentration was elevated postoperatively in the all cases from the first postoperative day. 2. There were a significant correlation between the preoperative BUN and [2* MG concentration [P< 0.01]. The correlation factor[r] in child group was 0.8512, and in adults 0.8636. 3. The maximum level of serum [2* MG in the both child and adult groups were noticed in 4th postoperative day as 2.61*0.80mg/ 1 in child group and 3.39*1.47 mg/ 4 in adult group, and there was a significant difference between the two groups statistically[P < 0.05]. 4. The pattern of changes of serum concentration of [2* MG with time was very similar with the changes of BUN, but in a case of ARF [expired with it] the changes of [2* MG was more remarkable. 5. There was a significant differences in the maximum level of [2* MG between the 2 group according to the ECC time [groups of below and above 60 minutes] [P< 0.01].

급성 충수염 환자의 혈액배양에서 동시에 분리된 Catabacter hongkongensis와 Alistipes indistinctus 1예

류지윤,김영진,이재준,조선영,박태성,이희주 대한진단검사의학회 2019 Laboratory Medicine Online Vol.9 No.3

Catabacter hongkongensis is an anaerobic gram-positive coccobacillus that was first isolated in Hong Kong. It is infectious and causes high mortality in patients with rare but underlying diseases. Alistipes indistinctus is an anaerobic gram-negative coccobacillus. This bacterium is a common member of the human intestinal microbiota. We report a case of C. hongkongensis and A. indistinctus isolated from blood cultures of a patient with acute appendicitis. A 35-year-old female patient with no specific medical history was admitted to the hospital due to abdominal pain, vomiting, nausea, and diarrhea experienced on the day before admission. On admission, laboratory tests revealed leukocytosis, neutropenia, and elevated C–reactive protein and procalcitonin levels. Following an abdominal computed tomography showing acute appendicitis with suspected perforation, emergency surgery was performed. Growth was observed in two anaerobic blood culture bottles after four days. After further culturing of the bacteria on Brucella Blood Agar, two types of bacteria were obtained. The two bacterial isolates, one gram-positive and one gram-negative, were unable to be identified using matrix assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS). Thus, 16S rRNA gene sequence analysis was performed, resulting in identification of the bacteria as C. hongkongensis and A. indistinctus. The patient was administered antibiotics and discharged two days after surgery. Although MALDI-TOF MS enables fast and accurate identification of bacteria, C. hongkongensis and A. indistinctus were not listed in the spectral library, and 16S rRNA gene sequence analysis was useful for identifying the two bacteria. Catabacter hongkongensis는 혐기성 그람 양성 구간균으로 홍콩에서 처음 동정되었다. 드물지만 기저질환이 있는 환자들에게서 감염되어 높은 사망을 일으키는 병원균이다. Alistipes indistinctus는 혐기성 그람 음성 구간균이다. 이 균은 장내 정상 세균총으로 알려져 있다. 본 증례에서는 급성 충수염 환자의 혈액 배양 검사에서 C. hongkongensis와 A. indistinctus가 동시에 동정된 1예를 보고하고자 한다. 특이 병력 없는 35세 여자 환자로 내원 전일 발생한 복통과 구토, 구역감, 설사증상으로 병원에 입원하였다. 입원하여 시행한 혈액 검사상 백혈구 수 상승, 호중구증가증, C-반응 단백 상승 그리고 프로칼시토닌 상승 소견 보였다. 복부 CT상 천공이 의심되는 급성충수염으로 응급 수술하였다. 이때 시행한 혈액배양에서 4일만에 두 개의 혐기성 배양병에서 양성 신호를 보였다. 브루셀라 배지에 계대배양하였고 그람 양성과 그람 음성 구간균이 분리되었다. MALDI-TOF MS로 동정이 되지 않아 16S rRNA gene 염기서열 분석을 시행하였고, 각각 C. hongkongensis와 A. indistinctus임을 확인하였다. 환자는 수술과 경험적 항생제 투여 후 증상 호전되어 2일 후 퇴원하였다. MALDI-TOF MS는 보다 빠르고 정확한 세균 동정이 가능하지만 C. hongkongensis와 A. indistinctus처럼 스펙트럼 라이브러리에 없는 상기 두 균의 동정에는 16S rRNA gene 염기서열 분석이 유용하였다.