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류영상,김진화,김상용 대한신경과학회 2019 대한신경과학회지 Vol.37 No.3
Cardiovascular disease, including stroke, is one of the major causes of death in diabetes. Numerous studies have long suggested reducing macrovascular complication such as ischemic vascular disease through intensive glycemic control, but none was successful proving the effect of glycemic control. Recently, new possibilities in cardiovascular disease reduction have been proposed through cardiovascular safety trials of newly developed anti-hyperglycemic agents. The purpose of this review is to introduce the traditional and newly developed anti-diabetic medications and review their effects regarding cardiovascular outcomes mainly focusing on stroke.
β-cyclodextrin과 arabic gum를 이용한 향료의 encapsulation제법과 분석에 관한 연구
류영상 ( Young-sang You ),윤영수 ( Young-soo Yoon ) 대한화장품학회 1995 대한화장품학회지 Vol.21 No.1
본 연구는 향장향이 갖고 있는 단점과 우려(피부알러지, 자극,향의 지속성 결여)를 개선,보완하고자 향료를 β-Cyclodextrin을 이용하여 포접시키고 Arabic Gum으로 이중 Encapsulation 시켰다. Paste 상태의 Capsulation 혼합물을 스프레이 드라이법을 사용하여 분말향료를 얻 었으며, GC, IR, UV 관능법으로 분석하였다. Fragrance oil was encapsulated with β-cyclodextrin and Arabic gum for double Encapsulation to imprve the demerits-cause the skin irritation, allergy and lack of odor fixative-. Powder fragrance was obtained from the paste phase using the method of spray dry. From the analyses (GC, IR, UV) and sensory tests, it was identified that fragrance was encapsulated in our reservoir.
류영상 ( Young Sang Lyu ),김진화 ( Jin Hwa Kim ),김상용 ( Sang Yong Kim ) 대한내과학회 2021 대한내과학회지 Vol.96 No.6
Hypoglycemia is common but can lead to life-threatening consequences. Accurate diagnosis is important to establish the appropriate treatment strategy. Most cases of hypoglycemia are caused by hypoglycemic agents, although it can occur in individuals without diabetes. A systemic and comprehensive diagnostic approach is required to diagnose hypoglycemia in patients without diabetes. It is important to perform appropriate blood testing during an episode of hypoglycemia. This review will focus on the definition, differential diagnosis, causes, and treatment of hypoglycemia, particularly in people without diabetes. (Korean J Med 2021;96:484-492)
당뇨병 환자에서 저용량 스타틴 사용에 따른 저밀도지단백콜레스테롤 강하효과
류영상(Young-Sang Lyu),김상용(Sang-Yong Kim) 조선대학교 의학연구원 2020 The Medical Journal of Chosun University Vol.45 No.1
Purpose: Recently, moderate to high-dose of statin were recommended for diabetic patients. However, it is not clear whether it is appropriate to all patients. The aim of this study is to evaluate the efficacy of low-dose statins for Korean diabetic patients. Methods: We analyzed a retrospective data in single diabetic center that consisted of Korean patients with diabetes who had been prescribed any of the low-dose statins (atorvastatin 10 mg, pitavastatin 2 mg, pravastatin 10 mg, or simvastatin 10 mg). We analyzed their lipid and safety profiles before and 3 months after each statin therapy. Results: After 3 months statin therapy, mean low density lipoprotein (LDL)-cholesterol reduction was -38.6% (interquartile range, -49.3% to -34.3%). Atorvastatin 10 mg (n=61), pitavastatin 2 mg (n=60), pravastatin 20 mg (n=63), and simvastatin 10 mg (n=64) reduced LDL-cholesterol level by 38.1%, 39.2%, 41.6%, and 38.4% respectively. Among the total subjects, 70.2% of the patients achieved a target LDL-cholesterol level <100 mg/dL, 68.8%, 72.4%, 70.6%, and 67.8% of the patients achieved a target in atorvastatin 10 mg, pitavastatin 2 mg, pravastatin 10 mg, and simvastatin 10 mg respectively. Conclusion: A low-dose statin was enough to manage LDL-cholesterol level in most Korean diabetic patients. The efficacies of those statins were higher than expected in Korean compared to Caucasian.
수도재배기간중(水稻栽培期間中)의 저온(低溫) 및 이앙기(移秧期) 한발출현유형(旱魃出現類型)과 분포(分布)
이량수,정영상,류인수,한원식,김병찬,Lee, Yang-Soo,Jung, Yeong-Sang,Ryu, In-Soo,Han, Won-Shig,Kim, Byung-Chan 한국토양비료학회 1983 한국토양비료학회지 Vol.16 No.2
우리나라 수도작기간중(水稻作期間中)의 재해기상(災害氣象) 위험도(危險度)를 파악(把握)하기 위하여 냉해(冷害)와 한발(旱魃)과 출현빈해(出現頻害)와 역별분포등(域別分布等)에 대한 조사(調査)를 실시한 결과(結果) 다음과 같았다. 1. 1970년(年) 이후(以後) 한발(旱魃)과 저온출현(低溫出現)이 많아졌으며 침수해(浸水害)의 발생은 감소(減少)하였다. 2. 저온유형(低溫類型)의 출현빈도(出現頻度)는 전기저온형(前期低溫型)과 장기저온형(長期低溫型)이 많았으며 지역별(地域別)로는 수원(水原) > 대구(大邱) > 광주(光州)의 순(順)이었다. 3. 수도이앙기(水稻移秧期) (4~6월(月)) 강수량(降水量)의 년도별(年度別) 변화 주기(週期)는 약(約) 15년(年)으로 나타나며 최근년(最近年)은 소강우(少降雨) 주기(週期)에 해당하는 경향(傾向)이었다. 4. 이앙기(移秧期) 한발빈도(旱魃頻度)는 대구(大邱), 포항지역(浦項地域)에서 가장 많았고, '82년도(年度) 강수량(降水量)과 저수율(貯水率)을 기준(基準)한 한발극심(旱魃極甚) 지역(地域)은 영남내륙(嶺南內陸) 및 서남해안지대(西南海岸地帶)이었다. The occurrence and regional distribution of low temperature and drought during rice cropping period in Korea were studied to characterize the climatic impacts. The long term changes in rice yield, air temperature and precipitation were analyzed, and regional distributions were characterized. The significant climatic impacts on rice yield were heavy rain or flood, drought and low temperature. Since 1910, the occurrence of drought was 29 times, that of flood was 24 times and that of low temperature was 9 times; however, the drought and flood damages were decreased due to expansion of irrigation system since 1970 but low temperature damage was remarkedly increased. The long term changes in air temperature since 1908 in Suweon showed that the 5-year moving average from July to August decreased while that from May to June increased. The occurrence probability of the long term and early term low temperature types were the greatest in Korea and were in order of Suweon, Daegu and Kwangiu. The long term changes in 10-year moving average precipitation from April to June showed a 15 year cycle and recent years were in low precipitation period. The drought frequencies were the highest in Daegu and Pohang area. According to the precipitation from April to June and resevtoir storage at late June, the severest dry area were the Youngnam inland and the southwest coastal area.