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      • SCOPUSKCI등재

        경추부 경막외 혈액 봉합술로 치료한 자발성 두개내 저압

        정성원(Sung Won Chung),도현우(Hyun Woo Do),이정구( 대한통증학회 1999 The Korean Journal of Pain Vol.12 No.1

        We teport a patient with spontaneous intracranial hypotension. In addition to the cardinal feature of a postural headache and a low CSF pressure, the patient also had subdural hematoma demonstrated by brain MRI. Radionuclide cisternography revealed a CSF leakage in the intracranium. CSF leakage from spinal meningeal defects may be the most common cause of this syndrome. The headache is a consequence of the low CSF pressure producing displacement of pain-sensitive structures, Methods of treatment are identical to those for post-dural puncture headaches. We experienced a patient with spontaneous intracranial hypotension developed in the intracranium who was successfully managed with a cervical blood patch.

      • KCI등재
      • 실험적으로 유도된 이독성 난청에서의 Ginkgo Extract의 효과

        이상흔,조영채,도현우,강현욱,조태환 경북대학교 병원 1997 경북대학교병원의학연구소논문집 Vol.1 No.1

        이독성 난청에서의 Ginkgo extract의 효과를 보고자 기닉픽 22마리를 대상으로 이음향방사를 측정하여 난청군과 치료군을 비교 검토한 바 성적을 요약하면 다음과 같다. 난청군에서의 DP-OAE는 대군조에 비해 전 주파수에서 감소 내지 소실을 보였으며4KHz 에서만 선택적으로 큰 감소를 나타낸것도 있었다. Ginkgo estract로 예방 치료한 군에서는 난청군에 비해 DP-OAE가 현저하게 출현 하였으며 정상 DP-OAE소견을 나타낸 것도 있었다. 난청치료군에서도 난청군에 비해 전체적으로 DP-OAE 가높게 출현되고 있었다. 이상의 소견으로 보아 Ginkgo estract가 이독성 난청과 감각신경성 난청에서의 예방 및 치료 효과의 가능성을 제시해 준다고 생각되는 바이다. This study was designed to investigate the effect of Ginkgo biloba extract on the kanamycin induced ototxicity in inner ears 22 guinea pigs. The animals were divied into 4 groups. In ototoxic group, kanamycin was injected 400mg/kg per day for 7 to 10 days. In preventive treated group, kanamycin with same dose and Ginkgo biloba extract(50mg/kg)were simultaneously injected daily for same duration. In post treated toup, Ginkgo extract was treated for 15 days in kanamycin injected group. The Preyer's reflex and DP-OAE (distortion product otoacoustic emissions) were used for the monitoring of hearing changes. In the ototoxic group, the amplitude of DP-OAE was marked decreased or disappeared in all test frequencies or 4KHz only. The Preyer's reflex was disappeared in all ototoxic group. In the preventive treated group with Ginkgo extract, normal DP-OAE or slightly decreased DP-OAE in 4 KHz was noticed. This finding was seemed to be similar to the post-treated group. From the above results, Ginkgo extract is suggested to have beneficial effects for the management of ototoxicity and sensorineural hearing loss.

      • KCI등재후보

        전신마취와 척추마취 하에 하지 수술시 구혈기에 의한 혈역학적 변화

        최윤정,도현우,전재규,김진모 啓明大學校 醫科大學 1999 계명의대학술지 Vol.18 No.2

        A tourniquet is commonly used to achieve a bloodless field in surgery of the extremities. However, tourniquet use occasionally has been associated with intranperative hypertension and with circulatory collapse after deflation. The purpose of this study is to define the hemodynamic changes in this setting using thoracic electrical bioimpedance (TEB) device. Twenty patients of ASA class I, scheduled for lower extremities surgery using a thigh tourniquet, were randomly divided into two groups. Group I underwent general anesthesia (including enflurane) and group Ⅱ underwent spinal anesthesia (0.5% bupivacaine 12.5 mg). The changes of blood pressure (BP), heart rate (HR), stroke index (SI), cardiac index (CI), systemic vascular resistance index (SVRI), and end-diastolic index(EDI) were measured (1) before induction, (2) just before inflation of tourniquet, (3) at the time of the maximal change of CI within 10 minutes after inflation of it, (4) just before deflation of tourniquet, and (5) at the time of the maximal change of CI within 10 minutes after deflation of it. During a tourniquet inflation, SI, CI and SVRI were markedly changed in group I , but not effectively changed in group H. During a tourniquet deflation, CI and SVRI were changed significantly in group I and only SVRI was decreased effectively in group Ⅱ (p<0.05). However, there were no significant changes in BP, HR, and EDI in both groups during a tourniquet inflation and deflation. In cases of the use of a thigh tourniquet for lower extremities surgery, the hemodynamic fluctuations of CI and SVRI are obviously less changed in the spinal than in the general anesthesia during the inflation and deflation of a tourniquet and prominent during 5-10 minutes just after inflation and deflation of a tourniquet. Accordingly, it is suggested that spinal anesthesia is preferred to general anesthesia for the use of a thigh tourniquet in patients scheduled for lower extremities surgery and close observation is required during 5-10 minutes just after inflation and deflation of a tourniquet.

      • SCOPUSKCI등재

        질식분만을 위한 경막외차단후 좌욕에 의해 유발된 회음부의 열탕화상

        김애라,전재규,도현우 대한마취과학회 1998 Korean Journal of Anesthesiology Vol.34 No.2

        Epidural block is one of the most effective methods of intrapartum pain relief in current practice. This is a case of a scalding burn resulting from a sitz bath long enough after epidural block for vaginal delivery. The patient received 7 ml of 0.25% bupivacaine mixed with 1 : 300,000 epinephrine and fentanyl 50 ㎍ for epidural block. Following delivery, the patient started complaining of voiding difficulty without any motor weakness 6 hours after the epidural block occured. At that time, the patient did not feel any hot or pain sensations during the 15 minutes of unintentional hot water application for sitz bath. Consequently, an approximately 5∼10% superficial second degree burn developed on her perineal and inner thigh region. (Korean J Anesthesiol 1998; 34: 444∼447)

      • SCOPUSKCI등재

        복강경하 전자궁적출술시 전신마취(Propofol/N2O, Enflurane/N2O)에 따른 혈역학적 변화

        김애라,정성원,전재규,도현우 대한마취과학회 1999 Korean Journal of Anesthesiology Vol.36 No.5

        Background : Laparoscopy with peritoneal carbon dioxide insufflation is a standard procedure in many gynecological departments. And more prolonged gynecological laparoscopic operations are being performed in recent years, and a steeper head-down position is required. Despite laparoscopic operations have many advantages, peritoneal insufflation of CO2 to create the pneumoperitoneum necessary for laparoscopy induces intraoperative hemodynamic changes that complicate anesthetic management of laparoscopy.The purpose of this study is to evaluate the effect of general anesthesia on hemodynamics during loparoscopic hysterectomy. Methods : Twenty six women undergoing laparoscopic hysterectomy were randomly allocated to either a propofol (Group 1, n=13) intravenous anesthesia or a enflurane (Group 2, n=13) anesthesia with fentanyl-N2O/O2-vecuronium. Hemodynamic parameters were measured before induction (T1), 5 min after induction (T2), 5 min after head-down (T3), 5, 10, 15, 20 min after pneumoperitoneum (T4, T5, T6, T7), 5, 10 min after deflation (T8, T9). The MAP, HR, CI, SVRI, SI were measured by transthoracic electrical bioimpedence method and automated blood pressure device. Results : The mean arterial pressure were increased during pneumoperitonem in both groups and heart rate were increased in Group 2. The cardic index were decreased in both groups after induction by 27.4 % in Group 1 and 25.7% in Group 2. The systemic vascular resistanace index were increased in both groups from head-down to after deflation by 68.3% in Group 1, 73.1% in Group 2 maximally. No significant changes of stroke index were observed during surgery in Group 1. Conclusions : Laproscopy with CO2 insufflation induces significant hemodynamic changes includig increases of MAP, SVR and a reduction of CI. And usual intraoperative hemodynamic monitoring; the blood pressure and heart rate give no information on the reduction in cardic output. (Korean J Anesthesiol 1999; 36: 828∼833)

      • SCOPUSKCI등재

        심폐회로술 중 Thiopental Sodium, Etomidate 및 Propofol 이 전신혈관저항과 정맥용량에 미치는 영향

        김애라,김진모,전재규,도현우 대한마취과학회 2000 Korean Journal of Anesthesiology Vol.38 No.1

        Background : The focus of this study is the effects of thiopental sodium. etomidate and popofol on systemic vascular resistance and venous capacitance during cardiopulmonary bypass with constant pump flow. Methods: Thirty patients (ASA Ⅲ) scheduled for open heart surgery were randomly divided into three groups. Anesthesia was induced with thiopental sodium 5 mg/kg, fentanyl 5 ug/kg and vecuronium 1 mg/kg. CPB was conduced with a membrane oxygenator using non-pulsatile flow and moderate hyputhermia. When rectal temperature and pump flow had been stable for 5 min, patients randomly received thiopental sodium 4 mg/kg, etomidate 0.3 mg/kg and propofol 2 mg/kg. Perfusion pressure and pump flow were measured 0,1,3,5, 10,15,20 and 30 min after administration. Results : The systemic vascular resistance index (SVRI) decreased to 84.3% of the cfmtrol values after thiopental sodium 4 mg/kg, to 74.7% of the control after etomidate 0.3 mgfkg and to 79.8% of the oontrol after propofol 2 mg/kg. SVRI returned to control vlue levels 3 min after the administration of thiopental sodium, 20 min after etomidate, and 5 min after propofol. Thiopental sodium, etomidate and propofol reduced venous reservoir volume 1 min after injection and the reduction was sustained throughout the all period of the cardiopulmonary bypass. Conclusions: The results indicate that thiopental sodium, etomidate and propofol dilate both resistance and capacitance vessels, but there was no correlation between the two vessels. (Korean J Anesthesiol 207; 38: 81∼88)

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