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      • KCI등재후보

        사용자조절소프트웨어를 이용한 백내장 수술의 임상결과

        노창래,김수영,주천기.Chang Rae Rho. M.D.. Su Young Kim. M.D.. Choun Ki Joo. M.D.. Ph.D. 대한안과학회 2006 대한안과학회지 Vol.47 No.5

        Purpose: To compare the effectiveness and safety of the hyperpulse phaco mode based on the custom control software with those of the conventional continuous phaco mode. Methods: This study included 560 eyes of 496 patients, which were divided into 2 groups according to the mode of phacoemulsification. Each group was further stratified into 4 groups according to their nuclear opacity. The following parameters were compared between groups having the same degree of nuclear opacity: the best corrected visual acuity preoperatively, at 1 day and 2 months postoperatively, the change of endothelial cell count and hexagonality preoperatively and at 2 months postoperatively, as well as the total phaco energy used in the operation. Results: There were no significant differences in visual acuity between control and experiment groups. As for change in endothelial cell count, there were also no statisticallysignificant differences. Hexagonality was significantly higher in the nuclear opacity groups 3 and 4 of the hyperpulse mode than those of the continuous mode. The absolute phaco time was significantly less in the nuclear opacity groups 1, 2 and 3 of the hyperpulse mode than those of the continuous mode. Conclusions: Phacoemulsification using the custom control software showed an advantage decrease in the total phaco energy and corneal endothelial cell damage. This result will improve the postoperative prognosis.

      • KCI등재후보

        소아에서 발생한 안부대상포진 1예

        노창래,이승재,전은정,정성근,Chang Rae Rho,Seung Jae Lee,Eun Jeong Jeon,Sung Kun Chung 대한안과학회 2006 대한안과학회지 Vol.47 No.7

        Purpose: We report a case of herpes zoster ophthalmicus in a 7-year-old child. Methods: A 7-year-old boy presented with acute onset of vesiculopapular rash covering his left forehead, upper eyelid, and side of the nose. He was admitted via the pediatrics clinic and was referred to ophthalmology clinic for ophthalmologic examinations. Results: On admission zoster ophthalmicus was limited to his skin and conjunctiva, but the disease progressed to zoster keratitis, uveitis, and meningitis. The patient was treated with topical, oral, and intravenous acyclovir. He had an uneventful recovery and was discharged. Conclusions: We experienced a case of zoster ophthamicus and meningitis in a patient without an apparent history of chickenpox.

      • KCI등재후보

        가토의 각막상피제거 후 목시플로사신과 가티플로사신의 창상 치유 효과 비교

        노창래(Chang Rae Roh),전은정(Eun-Jung Jun),정성근(Sung Kun Chung) 대한검안학회 2008 Annals of optometry and contact lens Vol.7 No.1

        목적: 주요 항생제 성분에 차이를 갖는 VigamoxTM, GatifloⓇ를 각막상피제거술을 시행한 후 가토에 점안하여 창상치유효과 및 전방 내 농도에 차이가 있는지 알아보고자 하였다. 대상과 방법: 가토 9마리(18안)를 무작위로 6.0 mm 직경의 각막상피제거술을 시행한 후 각 9안씩에 미국식품의약청에서 허가된 투여 방법대로 ViagmoxTM는 하루 3회씩 1주일간 점안하였고, GatifloⓇ는 첫 2일간 2시간마다 이후 5일간은 하루 4회씩 점안하였다. 각막상피 창상치유효과를 알아보기 위해 매일 사진을 찍었고, 전방 내 농도를 알아보기 위하여 술 후 1, 2, 7일에 전방천자를 실시하여 농도를 측정하였다. 결과: 평균 각막상피 창상치유시간은 VigamoxTM, GatifloⓇ 군에서 각각 2.8±0.45, 3.2±0.84일이었으며 두 군 간에 유의한 차이가 없었고(p=0.908), 일별 평균 각막상피 창상치유면적도 유의한 차이를 보이지 않았다. 전방 내 농도의 경우 GatifloⓇ 군에서 첫 2일에 VigamoxTM 군보다 좀더 높은 농도의 경향을 나타냈으나, 술 후 7일에는 유의한 차이를 보이지 않았다(p=0.342). 결론: VigamoxTM 군과 GatifloⓇ 군 간에는 항생제 성분에 차이가 있음에도 불구하고 1주일간의 단기간 사용에는 각막상피 창상치유효과 및 전방 내 농도에 유의한 차이를 보이지 않는 것으로 생각된다. Purpose: This study was performed to compare the effect on epithelial healing and penetration into aqueous humor of the fourth-generation fluoroquinolones following corneal epithelial removal. The administered drugs were moxifloxacin 0.5% eyedrops (VigamoxTM) and gatifloxacin 0.3% eyedrops (GatifloⓇ) which differentiates each other by its active ingredients. Methods: Eighteen eyes of 9 New Zealand white rabbits were randomized to receive moxifloxacin, gatifloxacin following anterior keratectomy with 6.0 mm in diameter. Moxifloxacin was administered three times daily for a week, and gatifloxacin was administered every two hours for the first two days and then four times daily for following five days according to the it Food and Drug Administration (FDA) approval. Beginning on postoperative day 0, photos were taken daily to measure the area of residual epithelial defects. Anterior chamber paracentesis was done to determine drug concentration at postoperative day 1,2, and 7. Results: Mean healing time for moxifloxacin and gatifloxacin was 2.8±0.45 and 3.2±0.84, respectively (p=0.908). No statistically significant differences of the mean healing time and mean area of healed corneal wound were noted among the two groups. A tendency for higher concentration of gatifloxacin to that of moxifloxacin was shown for the first postopertive two days but no difference was checked between two groups at postoperative day 7 (p=0.342). Conclusions: Although the two groups differ by the active ingredients, no significant differences were found in the epithelial healing effect or anterior chamber concentration with short-term dosing for 1 week in this trial.

      • KCI등재

        소아에서 발생한 안와의 B-세포 림프모구성 림프종 1예

        김정섭,노창래,도상희,박경신,양석우,Jung Sub Kim,M,D,Chang Rae Rho,M,D,Sang Hee Doh,M,D,Gyeong Sin Park,M,D,Suk Woo Yang,M,D 대한안과학회 2007 대한안과학회지 Vol.48 No.1

        Purpose: We report a case of orbital B-cell lymphoblastic lymphoma in a 7-year-old boy. Methods: A 7-year-old boy presented with proptosis and periorbital swelling of his left eye following a periorbital blunt trauma 1-month prior. During the course of routine ophthalmologic and radiologic examinatinos, the swelling spontaneously subsided without specific treatment. An outpatient follow-up was planned, but the swelling recurred 6 months later. An orbital CT and MRI showed an irregular mass with an indistinct margin in the left orbit, for which an incisional biopsy was performed. Results: The orbital mass consisited of monotonous small to medium sized lymphoid cells with evenly dispersed open chromatin, thin nuclear membrane and inconspicuous nucleoli. Immunohistochemistry revealed that the cells were positive for CD79a and TdT, but negative for CD3 and CD5. These findings were compatible with a diagnosis of B cell lymphoblastic lymphoma. Conclusions: Lymphoblastic lymphoma of the orbit should be suspected and considered in the differential diagnosis for children with acutely progressing orbital mass.

      • KCI등재

        가토 각막상피제거 후 염화벤잘코늄 첨가여부에 따른 가티플록사신의 창상치유효과 비교

        황형빈,노창래,정성근,Hyung Bin Hwang,Chang Rae Roh,Sung Kun Chung 대한안과학회 2008 대한안과학회지 Vol.49 No.6

        Purpose: This study was performed to compare the effect of fourth-generation fluoroquinolones gatifloxacin on epithelial healing and penetration into the aqueous humor following corneal epithelial removal. The administered drugs were ZymarTM and Gatiflo®, which differ from each other by the presence of benzalkonium chloride. Methods: Eighteen eyes of nine New Zealand white rabbits were randomized to receive either ZymarTM or Gatiflo® following anterior keratectomy with a diameter of 6.0 mm. Eyes were dosed with either antibiotic according to Food and Drug Administration (FDA) approval; specifically, ZymarTM and Gatiflo® were dosed every two hours for the first two days and then four times daily for the following five days. Starting from postoperative day 0, photos were taken daily to measure the area of the residual epithelial defects. Anterior chamber paracentesis was performed to determine the drug concentration at postoperative days 1, 2, and 7. Results: The mean healing times after ZymarTM and Gatiflo® treatment were 3.0±0.71 and 3.2±0.84 days, respectively (P=0.813). No statistically significant differences in the mean healing time and the mean area of the healed corneal wound were noted between the two groups. No difference in anterior chamber concentration was observed between the two groups at postoperative day 7 (P=0.362). Conclusions: Although the two drugs differ in that on drug has preservatives, no significant differences were found in the epithelial healing effect or anterior chamber concentration after short-term dosing for 1 week in this trial. J Korean Ophthalmol Soc 49(6):987-992, 2008

      • KCI등재

        통원 백내장 수술 후 개별 교육이 불안과 자가관리 수행에 미치는 영향

        조경숙,노창래,Kyung-Sook Cho,Chang Rae Rho 대한안과학회 2012 대한안과학회지 Vol.53 No.3

        Purpose: To investigate the influence of additional postoperative individualized teaching on the anxiety levels and self-care compliance of postoperative care in patients after one-day cataract surgery. Methods: The present study included 80 cataract patients who underwent phacoemulsification and posterior intraocular lens insertion performed by a single operator between January 2011 and February 2011. The control group consisted of patients who received postoperative education from an ophthalmology coordinator based on previous hospital policy. The experiment group consisted of patients who received additional individualized postoperative education from an operator in the recovery room. Trait anxiety on operation day, state anxiety on postoperative day 1, and self-care compliance and postoperative satisfaction at postoperative 1 month were evaluated. Results: There were no significant differences of trait anxiety levels on operation day or state anxiety on postoperative day 1 between the control and experiment groups. The experiment group revealed a higher score on the postoperative self-care compliance questionnaire, especially regarding care of the operation site. Conclusions: Individualized postoperative education increases self-care compliance level and contributes to improve postoperative recovery after one-day cataract surgery. J Korean Ophthalmol Soc 2012;53(3):412-419

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