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Switching dynamics and modeling of multi-domain Zr-Doped HfO2 ferroelectric thin films
노영지,정문영,윤정규,홍승현,박상현,강보수,안승언 한국물리학회 2019 Current Applied Physics Vol.19 No.4
HfO2-based ferroelectrics have attracted attention as promising materials for advanced memory applications owing to their negative capacitance effect, high scalability, and full-CMOS compatibility. Accordingly, the switching dynamics of HfO2 thin films have been actively discussed and simulated using the Landau-Khalatnikov equation (LK model). Although the simulated results agree with experimental results in many studies, there is a slight dissimilarity near the coercive field in the polarization-electric field curve. For accurate and general modeling, a new model that combines the conventional LK model and Euler's equation was proposed in this work. The model was examined under single-domain and multi-domain conditions. The simulated curves using the Landau-Euler method better fit with measured curves than those using the LK model.
데이브강,노승언,우정아,Tian Liu,Jung Hyun Bu,정아롱,임여리 한국뇌신경과학회 2011 Experimental Neurobiology Vol.20 No.2
The major defining pathological hallmarks of Alzheimer’s disease (AD) are the accumulations of Aβ in senile plaques and hyperphosphorylated tau in neurofibrillary tangles and neuropil threads. Recent studies indicate that rather than these insoluble lesions, the soluble Aβ oligomers and hyperphosphorylated tau are the toxic agents of AD pathology. Such pathological protein species are accompanied by cytoskeletal changes, mitochondrial dysfunction, Ca2+ dysregulation, and oxidative stress. In this review, we discuss how the binding of Aβ to various integrins, defects in downstream focal adhesion signaling, and activation of cofilin can impact mitochondrial dysfunction, cytoskeletal changes, and tau pathology induced by Aβ oligomers. Such pathological consequences can also feedback to further activate cofilin to promote cofilin pathology. We also suggest that the mechanism of Aβ generation by the endocytosis of APP is mechanistically linked with perturbations in integrin-based focal adhesion signaling, as APP, LRP, and β-integrins are physically associated with each other.
김용식,박민구,노승언,박성용,원종명 한국공업화학회 2001 한국공업화학회 연구논문 초록집 Vol.2001 No.-
종이의 표면처리는 표면강도, 평활도, 투기도, 물에 대한 저항성 둥 종이의 표면 특성을 부여하기 위해서 이용되고 있다. 표면 사이징의 중요성은 언급된 특성뿐만 아니라 내첨에 사용되는 내첨 사이즈제의 사용량 감소로 공정의 오염 및 제품의 표면지분을 감소시키는 특성을 부여한다. 또한 백상지의 다양한 용도에 적합한 수요자의 요구로 더욱 표면 사이징의 중요성이 지향되는 추세이다. 그러나 표면 사이징 처리에 사용되는 부원료의 pH, 온도, 전단력, 전하밀도에 따라 사이징 효과 및 공정의 오염을 야기시킨다. 본 연구에서는 표면 사이징에 사용되는 부원료 종류별 공정의 오염 정도를 분석한 결과 부원료 종류별 ionic demand가 낮을수록 전하중화에 따른 공정의 오염을 크게 야기 시켰으며, 온도와 전단력은 오염 정도를 더욱 촉진시킨 역할을 하였다. 이는 특히 표면 사이즈제 종류별 더욱 큰 차를 보였다.
Negative capacitance phenomena depending on the wake-up effect in the ferroelectric Si:HfO2 film
박상현,천민철,박솔민,박가연,정문영,노영지,안승언,강보수 한국물리학회 2019 Current Applied Physics Vol.19 No.3
Negative capacitance (NC) phenomena is recently suggested as a breakthrough that can lead to the improved transistor by decreasing the subthreshold swing. To understand the NC phenomena, we investigated the effects of the ferroelectric properties such as the remnant polarization depending on the switching cycles in Si-doped HfO2 thin film capacitor. The ferroelectric properties were controlled by using the wake-up effect, in which the remnant polarization enhances as the number of switching cycles increase. The relation between the wake-up effect and the voltage drop region with the negative differential capacitance were elucidated. The dynamic hysteresis loops were fitted based on Landau-Khalatnikov equation, and the free energy as a function of polarization was obtained. The Landau coefficients showed that the double-well feature of the free energy becomes more apparent due to the wake-up. Based on the wake-up effect on NC phenomena, we show that the NC phenomena is well described by Landau-Ginzburg theory of ferroelectrics.
Muhammad Umer Ashraf,Yideul Jeong,노승언,Yong-Soo Bae 대한약학회 2019 Archives of Pharmacal Research Vol.42 No.7
Many efforts have been made to improve theefficacy of dendritic cell (DC) vaccines in DC-based cancerimmunotherapy. One of these efforts is to deliver a DCvaccine more efficiently to the regional lymph nodes(rLNs) to induce stronger anti-tumor immunity. Togetherwith chemotaxis, transendothelial migration (TEM) isbelieved to be a critical and indispensable step for DCvaccine migration to the rLNs after administration. However,the mechanism underlying the in vitro-generated DCTEM in DC-based cancer immunotherapy has been largelyunknown. Currently, junctional adhesion molecules(JAMs) were found to play an important role in the TEM ofin vitro generated DC vaccines. This paper reviews theTEM of DC vaccines and TEM-associated JAM molecules.