만성 신부전 환자에서 99mTc - HMDP 골신티그램상 섭취정도와 혈중 osteocalcin , 부갑상선 호르몬치와의 상관관계

김춘열(Choon Yul Kim),정수교(Soo Kyo Chung),신경섭(Kyung Sub Shinn),손형선(Hyung Sun Sohn),김의녕(Euy Neyng Kim),방찬영(Chan Young Band),박철휘(Chul Whee Park),장윤식(Yoon Sik Chang) 대한핵의학회 1996 핵의학 분자영상 Vol.30 No.3

N/A In this preliminary study, plasma osteocalcin, PTH level and Tc-99m-HMDP (hydro- xymetylene diphosphonate) bone uptake(BU) were measured in 14 patients with chronic end-stage renal failure who were on maintenance hemodialysis. The aim of this study was to determine the difference of bone uptake between renal failure patients and normal volunteers, and to determine the correlation between bone uptake and osteocalcin a sensitive and specific marker of osteoblastic activity and PTH - a important hormone of bone metabolism. There was a statistically significant increase in 180 minute uptake in the patient group when compared to the normal volunteers while there was no statistically significant difference in 20 minute uptake. Plasma osteocalcin and PTH levels were also significantly elevated compared to normal values. But the correlation between osteocalcin, PTH and 20 and 180 minute bone uptake was not significant. In conclusion, our preliminary study suggests that, in chronic renal failure patients, 180 minute Tc-99m-HMDP bone uptake is increased significantly without direct correlation with serum osteocalcin or PTH levels. It seems that further study is needed to evaluate other unknown factors that may influence the direct correlation between bone uptake and plasma osteocalcin and PTH in patients with chronic renal failure.

Experimental Computer-Based Management System of Patients in Radiation Oncology

최일봉,김춘열,박용휘,Choi, Ihl-Bohng,Kim, Choon-Yul,Bahk, Yong-Whee The Korean Society for Radiation Oncology 1987 Radiation Oncology Journal Vol.5 No.2

근래에 와서 치료방사선학 영역에서의 전산화가 급속히 이루어지고 있으나 그 전산화의 대부분은 치료계획용 계산에 치우쳐져 있고 환자정보관리, 퇴원환자의 추적검사, 환자관리사무에 있어서의 전산화에 필요한 프로그램 등 환자관리에 필요한 프로그램은 매우 적으며, 상업적으로 개발된 프로그램은 일반화하기에는 많은 문제점을 갖고 있다. 이에 저자들은 16비트 개인용 컴퓨터를 이용하여 환자 현황 관리 프로그램을 시험 제작하였다. 1. 환자정보의 입력은 특별한 부호나 숫자를 사용하지 많고 현재 우리가 사용하는 영어나 한글을 그대로 쓸 수 있었다. 2 환자정보의 분석은 간단한 명령이나 키 동작으로 이루어질 수 있으며 특히 환자 현황에 대한 도표를 즉시 묘출할 수 있었다. 3. 환자관리정보의 내용은 기존 프린터를 이용하여 쉽게 문서화할 수 있으며, 학술발표, 강의재료 및 교육자료로 사용할 수 있었다. Currently, many computer systems are used in many areas of medicine including radiation oncology. For the most part, the computer system has proved to be useful in radiotherapeutic planning and dose calculation. There has been attempts to develop computer system including information management of patients, patient tracing, and office automation in radiation oncology department. But some of these available commercial systems have shortcomings. We developed a management system of patients in our radiation oncology department that integrated most of items for the evaluation of patents. In particular, the data were stored in a natural language (noncoded) and made themselves easily understandable by all clinical groups. In addition , the data could be isolated in files from which the computer could generate graphs and static data by the use of some simple commands. The system provided us with not only the functions of case review but functions of preparation of conferences, lectures and resident teaching.

상대정맥증후군의 CT 소견

임준,이재문,김춘열,박용휘,Lim, Jun,Lee, Jae-Mun,Kim, Choon-Yul,Bahk, Yong-Whee 대한영상의학회 1986 대한영상의학회지 Vol.22 No.5

Since early 1980's high resolution CT has been used for detectionof intrathoracic condition such as superior vena cava syndrome. Authors retrospectively analysed CT findings of 18 cases of proven SVC syndrome. The results were as follows : 1. The mean age was 50-years-old, and 14 cases were male. 2. Of 18 cases of SVC syndrome, 8cases had confirmed to be lung cancers, malignant thymoma and teratoma were rewpectively each 2 cases, and malignant lymphoma, mediastinal abscess, thyroid adenoma and metastatic tumor were 1 case. 3. CT findings were A. Abnormal SVC consisted of compression with displacement (44.4%),intraluminal thrombus(27.8%), and encasement(27.8%). B. The collateral pathways were the azygos-hemiazygos(88.8%), vertebral(50%), internal mammary(44.4%), and lateral thoracic route(33.3%).

급성 백혈병 환자에서 항암제 투여 후 뇌 CT 소견

임준,박석희,김춘열,박용휘,Lim, Jun,Park, Seog-Hee,Kim, Choon-Yul,Bahk, Yong-Whee 대한영상의학회 1988 대한영상의학회지 Vol.24 No.5

A study was performed to evaluate the atrophic changes of the central nerve system after chemotheraphy in the patients with acute leukemia. the computed tomographic findings and medical records 20 proven acute leukemia patients under 35 years-old who developed various CNS symptoms and signs during and/or after 2 coures of chemotheraphy were reviewed. The results were as follows : 1. Age distribution was 14 to 35 years (mean was 26 years) Male was 15. 2. Presenting clinical symptoms and signs were headache (16/20) nausea and vomiting (11/20) and loss of con-sciousness(5/20) 3. Brain atroply was noted in 16 patients including cortical and subcortical atrophy 15 cases and succortical atrophy 1 case. 4. Two cases of hemorrhage one each of intracranial hematoma and chronic subdural hematoma were found in addition to brain artophy. This showed that chemotherapeutic agents cause brain atrophy in a considerable number of the patients with symptomatic acute leukemia.

Experimental Computer-Based Management System of Patients in Radiation Oncology

Ihl Bohng Choi(최일봉),Choon Yul Kim(김춘열),Yong Whee Bahk(박용휘) 대한방사선종양학회 1987 Radiation Oncology Journal Vol.5 No.2

부분은 치료계획용 계산에 치우쳐져 있고 환자정보관리, 퇴원환자의 추적검사, 환자관리사무에 있어서의 전산화에 필요한 프로그램 등 환자관리에 필요한 프로그램은 매우 적으며, 상업적으로 개발된 프로그램은 일반화하기에는 많은 문제점을 갖고 있다. 이에 저자들은 16비트 개인용 컴퓨터를 이용하여 환자 현황 관리 프로그램을 시험 제작하였다. 1. 환자정보의 입력은 특별한 부호나 숫자를 사용하지 많고 현재 우리가 사용하는 영어나 한글을 그대로 쓸 수 있었다. 2 환자정보의 분석은 간단한 명령이나 키 동작으로 이루어질 수 있으며 특히 환자 현황에 대한 도표를 즉시 묘출할 수 있었다. 3. 환자관리정보의 내용은 기존 프린터를 이용하여 쉽게 문서화할 수 있으며, 학술발표, 강의재료 및 교육자료로 사용할 수 있었다. Currently, many computer systems are used in many areas of medicine including radiation oncology. For the most part, the computer system has proved to be useful in radiotherapeutic planning and dose calculation. There has been attempts to develop computer system including information management of patients, patient tracing, and office automation in radiation oncology department. But some of these available commercial systems have shortcomings. We developed a management system of patients in our radiation oncology department that integrated most of items for the evaluation of patents. In particular, the data were stored in a natural language (noncoded) and made themselves easily understandable by all clinical groups. In addition , the data could be isolated in files from which the computer could generate graphs and static data by the use of some simple commands. The system provided us with not only the functions of case review but functions of preparation of conferences, lectures and resident teaching.

온열요법시 온도변화가 정상조직에 미치는 영향

최일봉(Ihl Bohng Choi),김춘열(Choon Yul Kim),박용휘(Yong Whee Bahk) 대한방사선종양학회 1988 Radiation Oncology Journal Vol.6 No.2

The usefulness of hypertermia for cancer therapy have well been established. The purpose of the present investigation was to ascess the effect of step-up (42℃ → 44℃ sequence) and step-down (44℃ → 42℃ sequence) heating on the skin of the hind foot of the mouse. Hyperthermic treatments were given by immersion the hind foot of the mouse in circulating water baths. Skin response was studied by the leg reaction, which was scored according to a numerical scoring system proposed by Urano et al (1980). The results were as follws 1. The sking damage of 44℃ control group was more severe than 42℃ control group (p<0.0.5), except for 15min. heating group. 2. The skin damage of step-down group was more severe than step-up group (p<0.0.5). 3. The skin damage of 44℃ control group was more severe than step-up group when there is no difference in 44℃ heating time of step-up group from 44℃ control group (p<0.0.5). 4. In step-down group, the skin damage was more severe than 44℃ control group after preheating 45 min at 44℃ (p<0.0.5). Therefore, the above findings suggest the normal tissue damage by step-up heating was correlated with heating time of post step-up. The dropping of heating temperature in late phase had more severe damage of the skin than that in early phase during hyperthermia, and so contineous control of satisfactory temperature should be considered as the one of the most important factor for prognosis, complications of clinical hyperthermia

99mTc - HSA 신티그램을 이용한 쯔쯔가무시병에서의 장내단백소실 진단

박용휘(Yong Whee Bahk),김춘열(Choon Yul Kim),양우진(Woo Jin Yang),손형선(Hyung Sun Sohn),김성훈(Sung Hun Kim),신경섭(Kyung Sub Shin),김윤희(Yoon Hee Kim),정수교(Su Kyo Chung) 대한핵의학회 1996 핵의학 분자영상 Vol.30 No.1

N/A N/A

정상 한국인 대퇴골두의 99mTc - Tin Colloid 섭취율

박용휘(Yong Whee Bahk),김춘열(Choon Yul Kim),지원희(Won Hee Zhi),손형선(Hyung Sun Sohn) 대한핵의학회 1989 핵의학 분자영상 Vol.23 No.2

N/A Tc-99m-tin colloid distribution in the hip is studied in 76 patients with no hepatic and hip disorder, because knowledge of normal uptake pattern in the hip is important in evaluation of femoral head vasculature after a fracture. The uptake in femoral head is decreased or disappeared with increasing age due to conversion of red marrow to white marrow.

구내 건조증을 호소하는 환자에서 역동적 타액선 신티그라피: 정적영상과의 비교

김의녕(Euy Neyng Kim),손형선(Hyung Sun Sohn),최정은(Jung Eun Choi),김성훈(Sung Hoon Kim),정용안(Yong An Chung),정수교(Soo Kyo Chung),김춘열(Choon Yul Kim) 대한핵의학회 2001 핵의학 분자영상 Vol.35 No.1

N/A Purpose: In this study, we compared the quantitative characteristics of dynamic salivary gland scintigraphy with static scintigraphy in patients with clinical sicca syndrome using Tc-99m pertechnetate. Materials and Methods: Fifty-two parotid glands and 52 submandibular glands out of 26 patients with clinical sicca syndrome were studied by dynamic and static salivary gland scintigraphy. Ten normal volunteers were also studied as a control group for comparison of scintigraphic parameters. Ten minutes after injection of 370 MBq Tc-99m pertechnetate, we obtained pre-stimulus static images for a few minutes. Then dynamic salivary gland scintigraphy with lemon juice stimulation was performed for 20 minutes. Finally we obtained post-stimulus static images after dynamic images. On dynamic study, functional parameters such as uptake rate, secretion rate and re-uptake rate were calculated. The results of dynamic study and static images were compared. Results: On dynamic study, we could obtain functional parameters of salivary glands successfully. On dynamic study, 22 parotid glands and 22 submandibular glands out of each of 52 glands are abnormal. The static images demonstrated somewhat different results, of which reasons we could assume via dynamic study. Conclusion: Dynamic salivary gland scintigraphy using Tc-99m perechnetate were more functional than static images and might be useful in the assessment of the functional change of the salivary gland in patients with clinical sicca syndrome. (Korean J Nucl Med 2001;35:43-51)

갑상선 석회화의 방사선학적 양상

임준,심도철,박석희,김춘열,박용휘,Lim, Jun,Sim, Do-Chul,Park, Seog-Hee,Kim, Choon-Yul,Bahk, Yong-Whee 대한영상의학회 1986 대한영상의학회지 Vol.22 No.1

The purpose of this study was to analyse the various patterns of calcification demonstrated in the anterior and lateral neck roentgenograms of 213 unselected patients with thyroid enlargement. The patterns of thyroid calcifications were correlated with clinical, surgical and histological findings. The results were as follows : 1. Of 23 cases of thyroid enlargement, 180 cases were benign and 168 cases were female. 2. The calcification rate was high in the chronic thyroid enlargement. 3. The incidence of calcification was 30.2% in the malignancy and 17.2% in the benign disease. There was no calcification in the Hashimoto's diseases. 4. The nodular calcification was demonstrated in the both benign and malignant disease but curvilinear calcification was predominantly seen in benign disease.