응급의학과 전공의에 의한 장겹침증 초음파 검사는 가능한가?

김진휘,강보승,강형구,임태호,제상모,최혁중,박세훈 대한응급의학회 2012 大韓應急醫學會誌 Vol.23 No.5

Purpose: The aim of this study was to evaluate the sensitivity and specificity of ultrasonography of suspected ileocolic intussusception performed by emergency medicine (EM)residents who participated in a 2-hour focused ultrasound training program for intussusception. Methods: This was a 16-month retrospective, observational study. Pediatric patients with suspected ileocolic intussusception who underwent ultrasound performed by second or third year EM residents were included in the study. The gold standard was a diagnostic work-up performed by a radiologist or clinical follow-up, compared with the results of ultrasonography performed by EM residents. Results: A total of 38 patients were enrolled. The sensitivity of ultrasound performed by emergency medicine residents for prediction of ileocolic intussusception was 92.86% (66.13% to 99.82%), the specificity was 91.67%(73.00% to 98.97%), the positive likelihood ratio was 11.14(2.93 to 42.34), and the negative likelihood ratio was 0.08(0.01 to 0.52). Conclusion: Emergency residents can identify ileocolic intussusceptions with only minimal training, which could substitute for ultrasonography performed by radiologists when they are not immediately available.

Adjuvant therapy in high-risk early endometrial carcinoma: a retrospective analysis of 46 cases

김진휘,이성종,배정훈,이성하,배석년,남궁성은,박종섭 대한부인종양학회 2008 Journal of Gynecologic Oncology Vol.19 No.4

Objective: We assessed the prognostic factors and the efficacy of adjuvant therapy and reviewed randomized studies carried out on patients receiving adjuvant therapy with early endometrial carcinoma. Methods: One hundred and five patients that received primary surgical treatment for stage IB, IC and II endometrial cancer were enrolled in this study. The clinical outcomes were compared among the patients with variable prognostic factors and adjuvant treatments. Results: One hundred and five patients fulfilled the eligibility criteria and 46 patients (43.8%) underwent adjuvant therapy. Disease recurrence occurred in nine patients within a median time of 24 months. Cervical involvement was an independent prognostic factor for the disease-free survival rates. Eight of 16 patients with FIGO stage II disease received adjuvant chemotherapy consisting of cisplatin and etoposide (or cyclophosphamide) or combined chemoradiation. The 5-year disease-free survival rate for these patients was 87.5%, a value significantly higher than for patients that received radiation therapy alone (30%). Conclusion: Adjuvant chemotherapy or combination chemo-radiotherapy might be superior to radiation therapy alone in high-risk early endometrial cancer patients. Objective: We assessed the prognostic factors and the efficacy of adjuvant therapy and reviewed randomized studies carried out on patients receiving adjuvant therapy with early endometrial carcinoma. Methods: One hundred and five patients that received primary surgical treatment for stage IB, IC and II endometrial cancer were enrolled in this study. The clinical outcomes were compared among the patients with variable prognostic factors and adjuvant treatments. Results: One hundred and five patients fulfilled the eligibility criteria and 46 patients (43.8%) underwent adjuvant therapy. Disease recurrence occurred in nine patients within a median time of 24 months. Cervical involvement was an independent prognostic factor for the disease-free survival rates. Eight of 16 patients with FIGO stage II disease received adjuvant chemotherapy consisting of cisplatin and etoposide (or cyclophosphamide) or combined chemoradiation. The 5-year disease-free survival rate for these patients was 87.5%, a value significantly higher than for patients that received radiation therapy alone (30%). Conclusion: Adjuvant chemotherapy or combination chemo-radiotherapy might be superior to radiation therapy alone in high-risk early endometrial cancer patients.

이상치 탐색을 위한 통계적 방법

김진휘 건강보험심사평가원 2020 HIRA 정책동향 Vol.14 No.1

한국의 학교 검도의 도입 및 전개에 관한 연구 - 중,고등학교를 중심으로 -

김진휘,박귀순 한국체육학회 2015 전국체전기념 한국체육학회 학술발표회 Vol.2015 No.-

Can human papillomavirus testing predict residual/recurrent disease in patients with positive margins after LEEP?

김진휘,박태철 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-

목적: The purpose of this study was to evaluate the efficacy of human papillomavirus (HPV) testing during follow-up of patients with positive margins after loop electrosurgical excision procedure (LEEP) as a predictive factor for residual/recurrent disease. 방법: We retrospectively analyzed the medical data of patients who were treated using LEEP between January 1, 2000 and December 30, 2015. Post-LEEP follow-up was performed by liquid base Pap smear and HPV genotyping real-time PCR or DNA chip test. Residual/recurrent disease was defined as cytology of atypical squamous cells of unknown origin (ASC-US) or worse without a histology, or low grade squamous intraepithelial lesion (LSIL) histology or worse, at 4months or 12months after LEEP was performed. 결과: A total of 1,509 LEEPs were performed during the study period, and of these 1,263 patients with LSIL histology or negative surgical margin were excluded. Among the remaining 246 patients, 191 (77.6%) did not require any additional treatment (observation group) and 55 (22.4%) received re-operation. During follow-up, 59 patients (31%) had residual/recurrent disease in the observation group. Positive high-risk HPV testing at 4months after LEEP was significantly associated with residual/recurrent disease (relative risk 2.25; 95% confidence interval 1.55–3.80; p<0.05). 결론: HPV genotyping real-time PCR at 4months after LEEP might be a useful tool in the selection of patients requiring closer surveillance and in reducing the number of reoperation in patients with positive margins after LEEP.

GO-16 : A Pilot Study to Investigate the Efficacy of Fibrin sealant (Tisseel®) in Loop Electrosurgical Excision Procedure (LEEP)

김진휘,박금애,이근호,박태철 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-

The objective of the current study was to evaluate the efficacy and feasibility of fibrin sealant (Tisseel®) in loop electrosurgical excision procedure (LEEP) for cervical intraepithelial neoplasia (CIN 2 or 3). We designed a single-blinded prospective randomized study in consecutive in 40 women undergoing LEEP for biopsy-confirmed CIN 2 or 3 at Uijeongbu St. Mary`s Hospital, Korea. Informed consent was obtained from all participants. 2ml of fibrin sealant (Tisseel®) was applied to the uterine cervix of 20 women right after LEEP surgery (treatment group). We evaluated abdominal pain, vaginal bleeding, vaginal discharge and impairment in daily living after 1weeks using visual analogue scale questionnaires, and compared the results with the result of 20 women who did not receive fibrin sealant (control group). Among the 40 women who returned for the 1-week follow up after LEEP, 25 women (62.5%) reported at least one moderate to severe postprocedural symptom, including abdominal pain, vaginal bleeding, vaginal discharge and impairment in daily living. The mean duration of moderate to severe vaginal bleeding and impairment in daily living during postoperative week 1 for the treatment group and the control group was 0.3±0.80 days vs 1.7±2.36 days (p=0.015) and 0.9±1.37 days vs 3.00±2.62 days (p=0.060) respectively. Our results showed for the first time that the intraoperative application of fibrin sealant (Tisseel®) in LEEP can decrease the postoperative vaginal bleeding and impairment in daily living. Further large-scaled studies are needed to confirm the effectiveness of fibrin sealant (Tisseel®) in LEEP.

자궁내막증식증의 진단과 치료

김진휘 대한산부인과학회 2022 대한산부인과학회 학술대회 Vol.108 No.-

품은 마음,심는 말

김진휘 세계기독교통일신령협회 2003 統一世界 Vol.- No.12

우리가 흔히 ‘씨’라고 하면 눈에 보이는 자연계의 씨만을 생각하기 쉬운데, 그것보다 더 중요한 씨가 있다. 그것은 눈에 보이지 않는 인간의 ‘마음씨’와 ‘말씨’이다. 이것은 사람만이 갖는 특별한 ‘씨’로서 마음의 씨가 ‘품은 씨’라면 말하는 것은 ‘심는 씨’라고 볼수 있다. 왜냐하면 누구나 하는 말들은 품고 있는 마음속에서 비롯되어 표현되는 것이므로 어떤 마음을 품고 사느냐 하는 것이 매우 중요하다.

A case of malignant transformation of mitotically active Leiomyoma after total hysterectomy

김진휘 대한산부인과학회 2008 대한산부인과학회 학술대회 Vol.94 No.-

열처리 온도 변화에 따른 Viscose Rayon계 탄소펠트의 전기적 특성 연구

김진휘,안병길,윤호규 한국고분자학회 2004 한국고분자학회 학술대회 연구논문 초록집 Vol.2004 No.04