냉$\cdot$난방을 위한 축열시스템과 심야전력 요금제도

김진성,Kim, Jin-Sung 대한설비공학회 1989 설비저널 Vol.18 No.6

구취환자의 설태, 휘발성 황화합물, 타액분비율 및 타액내 secretory Immunoglobulin A에 대한 평가

김진성,엄국현,Kim, Jin-Sung,Eom, Guk-Hyeon 대한한방내과학회 2008 大韓韓方內科學會誌 Vol.29 No.1

Objectives : The aim of this study was to confirm the characteristics of oral malodor patients by evaluating the differences of salivary flow rate, secretory immunoglobulin A (sIgA) level in saliva between the patient and control groups, and the correlation with the tongue coating, volatile sulfur compound (VSC), salivary flow rate and sIgA level in saliva in the patients group. Methods : Forty-seven patients with oral malodor and twenty healthy volunteers were included in this study. Their tongue coating was assessed with the Winkel tongue coating index, and salivary flow rate, sIgA concentrations in saliva and the level of VSC in oral cavity were measured. Results : There were no significant differences of the salivary flow rate and the sIgA level in saliva between the patient and control groups, but there was a significant relationship between the accumulation of tongue coating and the level of VSC in oral cavity. Conclusions : Our results suggest that tongue coating is closely related to oral malodor, but further studies are needed to confirm the relationship between tongue coating and sIgA level in saliva.

이제마(李濟馬) 성정론(性情論)의 음양적(陰陽的) 원리(原理) - 성정기(性情氣)의 운동원리(運動原理)와 체질발현(體質發顯) 감정분류(感情分題)의 타당성(妥當性) -

김진성,Kim, Jin-sung 사상체질의학회 1998 사상체질의학회지 Vol.10 No.1

Sasang Constitutional Medicine is the constition medicine and the basis which constitution reveals is the distinction of the nature and emotion. Therefore the theory of the nature and emotion is the foundation which Sasang Constitution Medicine is coming into being. The author studied the progress that the distinction of the nature and emotion was formed and analized the phenomenon presented by the distinction of it as the principle of the movement of Yin and Yang. The results are following; 1. The beginning of the operation of the nature begins from some one part(cho ; 焦) among four part. That consists of the first factor of constitution-revelation. In accordance with the distinction of the nature, the second factor, that is the distinction of the emotion is determined and the united distinction of the nature and emotion presents the Sasang constitution. 2. The operation of the nature and emotion is the movement of Qi by the property of Yin and Yang and that is the phenomenon presented by the logical and scientifical law. 3. The ontology of Lee Je-ma is Qi-monism. 4. Four emotion(Sorrow, Anger, Joy, Presure) are not partional concept of the emotion but total concept which include all of it.

호흡동조 방사선치료의 2차원 선량 분포 정도관리를 위한 4D 정도관리 시스템 개발

김진성,신은혁,신정석,주상규,한영이,박희철,최두호,Kim, Jin-Sung,Shin, Eun-Hyuk,Shin, Jung-Suk,Ju, Sang-Gyu,Han, Young-Yih,Park, Hee-Chul,Choi, Doo-Ho 한국의학물리학회 2010 의학물리 Vol.21 No.2

Emerging technologies such as four-dimensional computed tomography (4D CT) is expected to allow clinicians to accurately model interfractional motion and to quantitatively estimate internal target volumes (ITVs) for radiation therapy involving moving targets. A need exists for a 4D radiation therapy quality assurance (QA) device that can incorporate and analyze the patient specific intrafractional motion as it relate to dose delivery and respiratory gating. We built a 4D RT prototype device and analyzed the patient-specific 4D radiation therapy QA for 2D dose distributions successfully. With more improvements, the 4D RT QA prototype device could be an integral part of a 4D RT decision process to confirm the dose delivery. 최근 시행되고 있는 호흡동조 방사선치료는 환자의 호흡의 주기를 이용하여 일정 주기에만 방사선을 조사하는 최신 방사선치료기술로 4D Computed Tomography와 RPM (Real-time Position Management) 시스템과 같은 호흡 모니터링 시스템의 개발로 환자들에게 시행이 되고 있다. 그러나 이러한 호흡동조 방사선치료에 대한 정도 관리는 아직 체계적으로 수행되고 있지 않으며 특히 환자에게 계획된 방사선치료선량이 환자의 호흡에 따라서 치료계획된 대로 조사되는지에 대한 정도관리에 대한 필요성이 요구되고 있다. 따라서 본 기관에서는 환자의 호흡신호를 사용하여 환자의 움직임을 동일하게 모사할 수 있는 팬텀을 제작하여 호흡동조 방사선치료의 2차원적 선량 분포를 평가할 수 있는 시스템을 구축하였고 특정환자의 호흡신호와 방사선치료계획을 이용하여 검증하였다. 환자의 호흡신호는 LabVIEW 7.0을 이용하여 모사하였고, 자체 제작한 팬텀 및 Kodak EDR2 필름을 사용하여 방사선을 조사한 뒤 gamma index를 사용하여 2차원 선량 분포를 비교 분석하였다. 본 연구에서 개발된 4D 정도관리 시스템을 좀 더 보완하여 호흡동조 방사선치료 과정에 있어서 조사선량의 적정성을 평가할 수 있는 정도관리 시스템으로 사용할 수 있을 것이라 생각된다.

적응화된 콘텐츠를 서비스하기 위한 사용자 단말기 프레임워크 설계 및 구현

김진성,이재동,Kim, Jin-Sung,Lee, Jae-Dong 한국정보처리학회 2009 정보처리학회논문지D Vol.16 No.5

인터넷의 발달과 멀티미디어 콘텐츠 수요의 증가에 따라 콘텐츠 산업이 발달하고 있다. 하지만 현재 콘텐츠 산업은 제한된 환경(사용자 디바이스 환경, 네트워크 환경 등)에서 동일화된 콘텐츠를 제공하고 있다. 또한, 사용자의 상황 및 감성에 맞는 콘텐츠를 서비스하기 위해서는 사용자가 콘텐츠를 검색하여 찾아야하는 어려움이 있다. 이에 사용자의 상황 및 감성에 따라 콘텐츠를 제공하는 시스템에 대한 필요가 대두되고 있다. 이에 본 논문에서는 유비쿼터스 환경에서 사용자가 언제, 어디서든지, 다양한 디바이스를 통해 사용자의 상황 및 감성 정보에 따라 적응화된 콘텐츠를 제공할 수 있는 시스템을 제안하고 사용자 단말기 상에서 적응화된 콘텐츠를 제공받을 수 있는 사용자 단말기 프레임워크를 설계하고 구현한다. According to development of internet and an increase in demand of multimedia contents, the contents industry is being developed. However, they are served same contents in the limited environment(user device environment, network environment) of the present contents industry. And users have difficulties in searching and finding contents since they are served contents they want and contents suitable to diverse context and affection. Therefore, it is necessary to make a system offering contents according to context and affection of users. The study proposes the system to offer contents suitable to context and affection of users whenever and wherever through diverse devices in a ubiquitous environment and designs/implementation a user device framework system that users can be offered contents suitable to their devices.

반모가 대장암세포에 미치는 영향

김진성,윤상협,류봉하,류기원,김현일,Kim, Jin-Sung,Yoon, Sang-Hyub,Ryu, Bong-Ha,Ryu, Ki-Won,Kim, Hyeon-Yil 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.2

The study examines the anti-cancer effects of the hot water extract of Mylabris phalerata(MP) using SNU-C5 cell lines. Microscopic analysis showed that 12 hours after MP treatment, the number of dead cells increased prominently. Significant cell death was observed 12, 24, and 48 hours after MP treatment through trypan blue exclusion testing. This suggests that MP is time-dependently cytotoxic. Mitotracker Red CMXRos staining and flowcytometry revealed that MP decreased mitochondrial membrane potentials. The absence of peaks on PI staining showed that DNA damage occurred in MP treated cells. Taken together, measurements suggest that MP has a strong anti-cancer effect on SNU-5 cell lines, and that this is likely to be due to the destruction of mitochondria and DNA damage.

집합주택단지 생활가로 조성 사례의 활용과 계획적 의미 분석

김진성,이현진,양우현,Kim, Jin-Sung,Lee, Hyun-Jin,Yang, Woo-Hyun 한국주거학회 2007 한국주거학회 논문집 Vol.18 No.6

In Korea, open spaces of urban housing do not serve residents as "regular living areas". We carried out research on the "streets" of urban housings in that the meaning of traditional "streets", playing roles which are not only means of passage but also boundary of life, cannot include present meaning of "streets" of the urban housing. This research is to propose the direction of planning Community Streets for the recovery of the public- and communal urban housing's streets, researching the present employment condition of Community Streets that were prepared recently. Working with 3 complexes which have been completed since 2000, We studied the present employment condition and planned signification, according to the conditions of their surroundings, the physical conditions of Community Streets, and the relationship among main apartment buildings, open spaces, and facilities. From this study, We came up with several suggestions that can present the planning line of Community Streets. Therefore this research is to create the Community Streets for the activity of the streets, the recovery of the community, and improvement of ambulatory environment.

Development of Video Image-Guided Setup (VIGS) System for Tomotherapy: Preliminary Study

김진성,주상규,홍채선,정재원,손기홍,신정석,신은혁,안성환,한영이,최두호,Kim, Jin Sung,Ju, Sang Gyu,Hong, Chae Seon,Jeong, Jaewon,Son, Kihong,Shin, Jung Suk,Shin, Eunheak,Ahn, Sung Hwan,Han, Youngyih,Choi, Doo Ho Korean Society of Medical Physics 2013 의학물리 Vol.24 No.2

초고압 전산화단층촬영(megavoltage computed tomography, MVCT)이 단층치료(Tomotherapy) 환자의 치료 자세 교정 방법으로 사용되고 있다. MVCT는 부가적인 방사선 피폭뿐만 아니라 전체 치료 시간이 길어지는 단점을 가지고 있다. 이러한 문제점 해결을 위해 비디오 영상기반 환자 치료 자세 교정 시스템(video image-guided setup system, VIGS)을 개발했다. 단층치료 장치내 갠트리에 직각으로 2대의 비디오 카메라를 장착하고 이로부터 얻은 영상을 이용하여 환자의 자세 오차를 측정하는 프로그램을 자체 개발했다. 개발된 시스템은 사용자에 의해 정의된 관심 영역에서의 에지 검출(edge detection) 결과를 기반으로 자동 정합을 통해 자세 오차를 찾도록 고안되었다. 두경부 환자를 묘사하기 위해 휴먼 팬톰을 이용하여 컴퓨터 단층 치료계획 영상을 획득한 후 전산화 치료계획을 수행했다. 실제 치료 상태를 재현하기 위해 고정 용구를 이용하여 팬톰을 고정했으며 전산화치료계획 결과로 부터 팬톰 자세 검증을 위한 기준 MVCT 영상을 획득했다. 팬톰을 치료 위치에 위치시킨 후 MVCT 영상을 얻고 이를 기준 MVCT영상과 비교하여 치료계획시와 동일환 자세가 되도록 위치를 교정했다. 교정된 자세에서 VGIS를 이용하여 기준 비디오 영상을 획득했다. 10회 걸쳐 MVCT 영상을 이용한 자세 교정과 VIGS를 이용한 비디오 영상기반 자세 교정을 각각 수행하여 두 방법간의 교정 값 차이(상관 분석)와 분석 시간을 비교했다. 팬톰 위치 교정 시간은 VIGS 시스템($41.7{\pm}11.2$ seconds)이 MVCT 방법($420{\pm}6$ seconds)에 비해 현저히 적게 조사됐다(p<0.05). 하지만 두 방법간의 위치 오차 분석 결과 통계적으로 유의한 차이는 보이지 않았다(x=0.11 mm, y=0.27 mm, z=0.58 mm, p>0.05). VIGS시스템이 짧은 시간에 정확한 위치 오차 감지 능력을 보여 이의 개발이 단층치료의 절차를 효율적으로 개선하는데 효과적일 것으로 생각된다. At present, megavoltage computed tomography (MVCT) is the only method used to correct the position of tomotherapy patients. MVCT produces extra radiation, in addition to the radiation used for treatment, and repositioning also takes up much of the total treatment time. To address these issues, we suggest the use of a video image-guided setup (VIGS) system for correcting the position of tomotherapy patients. We developed an in-house program to correct the exact position of patients using two orthogonal images obtained from two video cameras installed at $90^{\circ}$ and fastened inside the tomotherapy gantry. The system is programmed to make automatic registration possible with the use of edge detection of the user-defined region of interest (ROI). A head-and-neck patient is then simulated using a humanoid phantom. After taking the computed tomography (CT) image, tomotherapy planning is performed. To mimic a clinical treatment course, we used an immobilization device to position the phantom on the tomotherapy couch and, using MVCT, corrected its position to match the one captured when the treatment was planned. Video images of the corrected position were used as reference images for the VIGS system. First, the position was repeatedly corrected 10 times using MVCT, and based on the saved reference video image, the patient position was then corrected 10 times using the VIGS method. Thereafter, the results of the two correction methods were compared. The results demonstrated that patient positioning using a video-imaging method ($41.7{\pm}11.2$ seconds) significantly reduces the overall time of the MVCT method ($420{\pm}6$ seconds) (p<0.05). However, there was no meaningful difference in accuracy between the two methods (x=0.11 mm, y=0.27 mm, z=0.58 mm, p>0.05). Because VIGS provides a more accurate result and reduces the required time, compared with the MVCT method, it is expected to manage the overall tomotherapy treatment process more efficiently.

반모가 수종의 인체 암세포에 미치는 영향

김진성,윤상협,류봉하,류기원,정명채,Kim, Jin-Sung,Yoon, Sang-Hyub,Ryu, Bong-Ha,Ryu, Ki-Won,Jung, Myung-Chai 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.2

Object : Objective: This study was conducted to investigate the anti-cancer effects of Mylabris phalerata (반모) in some kinds of cancer cells. Materials and Methods: Some kinds of cancer cells lines were treated. We used nine kinds of cancer cell lines, such as stomach cancer cells (Kato), lung cancer cells (Calu-1, NCI-H 1395), urinary bladder cancer cells (HS789T), bone cancer cells (Saos-2), brain cancer cells (SK-N-MC), liver cancer cells (Hep-G2), skin cancer cells (Mo-1) and prostate cancer cells (PC-3) with the water decoction of Mylabris phalerata. The histological changes of all cell lines in the media (RPMI-1640) containing the decoction of Mylabris phalerata were observed and we examined cell death assay by trypan blue exclusion testing was examined. Finally, the change of mitochondrial membrane potential was measurd and the inhibitory effect of Mylabris phalerata on cell increase was examined by analyzing the cell cycle. Results: In histologic change all cancer cell lines showed withdrawn and floating appearance that is typical in cellular impairment. Most of the cell lines showed over 50% death rate after 24 hours in trypan blue exclusion tests. Especially the stomach, urinary bladder. brain and liver cell lines showed over 30% death rate after 12 hours. All cell lines treated with Mylabris phalerata were less stained than the control group and the mitochondrial membrane potential in the Mylabris phalerata treated cell lines was markedly lower than that in the control group. The measurement of DNA quantity in all cell lines showed the disappearance of the peak and the thickened left axis, which suggests that all cellular DNA degraded. Conclusion: Mylabris phalerata had cytotoxicity on various kinds of cancer cell lines and the mechanism of that was the impairment of mitochondria by the breakdown of the mitochondrial cell membrane. We propose that this is in part attributable to the destruction of DNA in cancer cells.

Knowledge Conversion between Conceptual Graph Model and Resource Description Framework

김진성,Kim, Jin-Sung Korean Institute of Intelligent Systems 2007 한국지능시스템학회논문지 Vol.17 No.1

On the Semantic Web, the content of the documents must be explicitly represented through metadata in order to enable contents-based inference. In this study, we propose a mechanism to convert the Conceptual Graph (CG) into Resource Description Framework (RDF). Quite a large number or representation languages for representing knowledge on the Web have been established over the last decade. Most of these researches are focused on design of independent knowledge description. On the Semantic Web, however, a knowledge conversion mechanism will be needed to exchange the knowledge used in independent devices. In this study, the CG could give an entire conceptual view of knowledge and RDF can represent that knowledge on the Semantic Web. Then the CG-based object oriented PROLOG could support the natural inference based on that knowledge. Therefore, our proposed knowledge conversion mechanism will be used in the designing of Semantic Web-based knowledge representation and inference systems.