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      • KCI등재후보

        한방병원에 내원한 이명환자의 특성 및 삶의 질 분석

        김자혜,김민희,신상호,고우신,김훈,윤화정,Kim, Ja-Hye,Kim, Min-Hee,Shin, Sang-Ho,Ko, Woo-Shin,Kim, Hoon,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2006 한방안이비인후피부과학회지 Vol.19 No.2

        Backgroun : Tinnitus is common disorder with many possible causes and a symptom of many different diseases but has no effective treatment. Approximately 20% of tinnitus patients experience the disorder to a degree that their quality of lift and productivity are impaired. Objective : This study was conducted to investigate the characteristic of the tinnitus patients and the impact of tinnitus on quality of life. Methods : 103 patients un recruited in this study who was ill with tinnitus. They wrote out the queslicumaire about tinnitus and the Tinnitus Handicap Inventory(THI). Result : THI score have relation to set the period of birth, the loudness of tinnitus and the items of attending symptoms. Conclusion In this study, tinnitus have influence on patients' quality of life. We expect this study to provide the base data for the effective treatment and the high qualify of patients' life.

      • KCI등재

        이명(耳鳴)의 한방(韓方) 치료(治療)에 의한 삶의 질 개선(改善) 효과(效果)

        김자혜,김민희,신상호,고우신,김규곤,윤화정,Kim, Ja-Hye,Kim, Min-Hee,Shin, Sang-Ho,Ko, Woo-Shin,Kim, Kyu-Kon,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2006 한방안이비인후피부과학회지 Vol.19 No.3

        Background : Tinnitus is a common symptom in outpatients of Otolarygology but has no correct diagnosis and effective treatment. Patients with tinnitus experienced the disorder to a degree that their quality of life and productivity are impaired. Objective : This study was conducted to investigate the change of THI score, the number of attending symptoms for the Korean medical treatment. And we investigated that the interrelationship is in existence as sex, age. Methods : Fatty patients were recruited in this study who was ill with tinnitus. They wrote out the questionnaire about tinnitus and the Tinnitus Handicap Inventory(THI) before and after treatment. The Korean medical treatment include a herb remedy, acupuncture. Result : THI score changed before and after treatment remarkably, and the number of attending sysmptoms also decreased noticeably. Relativity of questionnaires before and after treatment has difference as sex and age. Conclusion : Before and after treatment, the patients's THI score change significantly. In this study, the Korean medicine has effect on patients's quality of life with tinnitus. We expect that this study inform the effect of Korean Medicine about tinnitus and THI is the good questionnaire for measureing quality of patients' life with tinnitus for Korean medical doctors.

      • 파브리병에서 효소대치요법의 장기적 효과

        김자혜,조자향,최진호,이범희,유한욱,Kim, Ja Hye,Cho, Ja Hyang,Choi, Jin-Ho,Lee, Beom Hee,Yoo, Han-Wook 대한유전성대사질환학회 2014 대한유전성대사질환학회지 Vol.14 No.1

        Fabry disease is an X-linked disease caused by deficiency of the lysosomal enzyme alpha-galactosidase A. Affected males present anhydrosis, acroparesthesia and angiokeratoma, and subsequently cardiac, cerebral and renal complications are followed. Females and atypical variants show heterogeneous clinical symptoms. In 2001, two recombinant enzymes were approved for Fabry disease: agalsidase alpha and agalsidase beta. Since the introduction of enzyme replacement therapy (ERT), the number of long-term follow-up studies has been reported. Long-term ERT showed effectiveness on renal function in patients with chronic kidney disease, decrease or stabilization of left ventricular mass, and improvement of pain and quality of life. However, there were limited effects on cerebrovascular events and their mortality. Current literatures on the clinical effect of ERT have reported limited datain adult patients who have already advanced disease. Therefore, further study for pre-symptomatic patients and atypical variants is needed to verify the impact of ERT. This review summarized recent progresses in ERT and limitations of long-term effect of ERT in patients with Fabry disease.

      • 3-Methylglutaconic aciduria의 진단 및 평가

        김자혜,Kim, Ja Hye 대한유전성대사질환학회 2016 대한유전성대사질환학회지 Vol.16 No.1

        3-Methylglutaconic aciduria (3-MGA-uria)는 임상적 및 유전적으로 다양한 대사질환들을 총칭하는 질환군이다. 대부분의 경우 소변에서 3-MGA가 약간 증가되어 있거나 다른 대사물질이 같이 분비되는 경우에는 다른 대사질환이나 미토콘드리아 질환 등을 감별해야 한다. 그러나 지속적이며 반복적으로 소변 유기산 분석에서 3-MGA가 40-1,000 mmol/mol creatinine으로 상승되어 있는 경우에는 3-MGA-uria를 일으키는 질환을 감별해야 한다. 3-MGA-uria는 5가지 타입의 질환으로 분류되어 있고 Leucine 대사 질환인 일차성 3-MGA-uria와 4가지의 미토콘드리아 이상질환이 포함되어 있으며 임상적 및 생화학적 소견은 다양하게 나타날 수 있다. 일차성 3-MGA-uria인 3-methyl-glutaconyl-CoA hydratase 결핍증 환자에서는 소변의 3-MGA가 다른 질환군에 비해 많이 증가되어 있고 소변에서 3-hydroxyisovaleric acid가 분비되는 것이 감별점이라 할 수 있다. 다른 종류의 3-MGA-uria의 경우에는 대개 임상적으로 잘 분류가 되어 있는 Barth 증후군, Costeff 증후군, TMEM 70 결핍, MEGDEL 증후군, and DCMA 증후군 등이 포함되어 있어 시신경 검사, 심장초음파 검사 및 발달 검사 등을 통하여 감별진단에 이를 수 있다. 이에 본 종설에서는 선별검사를 통해 3-MGA-uria가 양성이 나온 환자들의 적절한 진단 및 치료를 위한 지침을 제시하고자 한다. The 3-methylglutaconic aciduria (3-MGA-uria) is a heterogeneous group of several inborn errors of metabolism characterized by increased urinary excretion of 3-methylglutaconic acid. In most cases, 3-MGA is only slightly increased and combined with other metabolites. However, repeated and significant excretion of 3-MGA (40->1,000 mmol/mol creatinine) is a hallmark of the disorders of 3-MGA-urias. There have identified five distinct types of disorders: inborn errors of leucine metabolism and four disorders of mitochondrial dysfunction through different mechanism. The range of clinical and biochemical findings in this condition is variable. In the patients with 3-methylglutaconyl-CoA hydratase deficiency, increased 3-hydroxyisovaleric acid is useful in the differential diagnosis. Other forms of 3-MGA-urias are welldefined clinically such as Barth syndrome, Costeff syndrome, TMEM 70 defect, MEGDEL syndrome, and DCMA syndrome. We provide an overview of the expanding clinical spectrum and differential diagnosis of the 3-MGA-urias.

      • KCI등재후보

        알레르기 비염의 대체의학적 치료에 관한 최근 논문경향 분석 - Entrez Pubmed 위주

        김자혜,신상호,김미보,고우신,윤화정,Kim, Ja-Hye,Shin, Sang-Ho,Kim, Mi-Bo,Ko, Woo-Shin,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2007 한방안이비인후피부과학회지 Vol.20 No.1

        Background : Allergic rhinitis is the most frequently occuring immunological disorder. It affects men, women and children and represents significant cost in terms of suffering and loss of productivity. Objective & Methods : We referred to the information through Entrex Pubmed from 2004 to 2007 January about alternative medicine for allergic rhinitis, 9 treatises. Results : About 9 treatises, 2 treatises were for the acupuncture treatment, I treatise was for the acupuncture and chinese herbal medicine, 2 treatises were for the single substance(butterbur, soy sauce ingredients), 1 treatise was for the homeopathic preparation, 1 treatise was for the ayur-veda herbal treatment, 1 treatise was for the ultraviolet light phototherapy, 1 treatise was for the systematic review of alternative medicine. Except 2 treatises for the acupuncture treatment, 6 treatises used the double-blind, randomized, placebo-controlled methods. As a result, we found 5 treatises that treat group had more improvement than control group, 3 treatises that treat group had no difference control group on effect significantly. 1 review article exhibited the most of alternative medical literatures were inadequate methodologically and therapeutic efficacy alternative treatment for allergic rhinitis was not supported by currently available evidence. Conclusion : We found that treatises about the alternative medicine for allergic rhinitis were more and more published. We were supposed that many internal treatises were published adequately by methodology to prove Korean medical treatment effects for allergic rhinitis.

      • KCI등재

        제2언어 학습자의 자기효능감 증진을 위한 교사의 역할 -영화 < 굿모닝 맨하탄(English Vinglish) >에 나타난 제2언어습득과정을 중심으로-

        김자혜 ( Kim Ja-hye ) 겨레어문학회 2018 겨레어문학 Vol.60 No.-

        본 연구는 영화 <굿모닝 맨하탄>에 나타나는 제2언어습득 양상을 밝히고 그 기저에서 기능하고 있는 자기효능감의 중요성과 교사의 역할에 대하여 알아보았다. 우선 영화 안에 나타나는 제2언어습득의 양상을 세 부분으로 나누어 살펴본 후 각 부분에서 나타난 제2언어습득에서의 자기효능감의 역할에 대해 알아보았다. 첫 번째는 제2언어를 모름으로 인한 문제를 학습의 동기로 전환하여 자기효능감을 자극하는 것이다. 두 번째는 목표어를 학습자와 관련 있는 실생활에서 적용할 수 있게 함으로 자기효능감을 강화하는 것이다. 한편 배운 내용을 실제로 활용하는 데 있어서 실수에 대한 두려움이 발동해 자기효능감에 위기가 나타날 수 있다. 이때 교사는 학습자가 실수에 대한 관용적인 자세를 가지고 두려움을 극복함으로 모험시도를 할 수 있게 하고 다양한 활동을 준비하는 것이 필요함을 논의했다. 마지막은 학습자가 습득한 제2언어가 삶과 통합되고 자기를 재발견 및 삶의 확장을 이룰 수 있게 하는 것으로, 학습자의 습득 과정 중 처음-중간-끝을 비교하게 함으로써 자기효능감의 확충을 이루게 한다. The purpose of this study is to identify the second language acquisition patterns in the film "English Vinglish" and to examine the importance of self - efficacy and the role of teachers in the basics. First, we examined the aspects of second language acquisition appearing in movies and examined the role of self-efficacy in second language acquisition in each section. The first is to stimulate the self - efficacy by turning the problem of not knowing the second language into motivation for learning. The second is to strengthen the self-efficacy by making it possible to apply the target language in the real life related to the learner. On the other hand, a fear of mistakes can be triggered in utilization of the contents learned, and a crisis may appear in self - efficacy. At this time, the teacher discussed the learner 's tolerance for mistakes and the need for learners to prepare for various activities and to try adventure by overcoming fear. Finally, the second language acquired by the learner integrates with life and rediscovers oneself. By making the learner 's first, middle, and final comparisons, he or she achieves the expansion of self - efficacy.

      • KCI등재

        <짐승말 알아듣는 이야기>를 통해 본 경계인 규정 원리 및 의미

        김자혜 ( Kim Ja-hye ) 한국문학치료학회 2018 문학치료연구 Vol.49 No.-

        이 논문에서는 민담 <짐승말 알아듣는 이야기>를 통해 내부들이 경계인을 규정하는 원리와 민담에서 이야기하고 있는 경계인의 의미에 대해 고찰하였다. 먼저 이야기 안에 등장하는 인물 중 짐승말을 듣는 사람을 ‘다름’으로 인해 대다수의 사람들에 의해 배제당하는 경계인으로 보았다. 그러나 이들은 자신들이 가진 능력을 솔직하게 밝힘으로써 자기 존재에 대해 당당함을 보이고 있다. 한편 이들은 자신들이 다른 사람들과 달리 특별하거나 독특하다는 생각을 하지 않으며 단순히 한 공동체 안에서 같이 생활하는 일부라는 인식을 가지고 있다. 그래서 솔직하고 당당한 모습을 보임을 살펴보았다. 이에 반해 원님이나 남편은 공동체의 다수를 구성하고 있는 내부인으로 보았다. 내부인들은 자신들의 상식과 경험에 근거해 자신과 다른 사람들을 공동체의 가장 밖으로 밀어냈다. 경계인을 규정하는 주체들은 자신들의 상식을 기준으로 하여 옳고 그름을 판단한다. 결국 이러한 판단은 자신들의 생각에 합당하지 않은 사람을 공동체의 가장자리로 위치시킨다. 한마디로 개인이나 집단의 편견이 경계인을 규정하는 요소가 되는 것이다. 또한 민담에 등장한 인물들의 행동 양상을 통해 경계인을 규정하는 그 기준 자체를 의심함으로 내부인과 경계인을 나누는 것이 무의미하다는 것을 확인할 수 있었다. 처음부터 경계인을 규정하는 기준 자체가 주관적이기 때문에 그 기준에 따르면 누구나 경계인이 될 수 있고 누구나 외부인이 될 수 있다는 것을 잘 보여주고 있었다. This study examined the principle by which insiders define a marginal man in the folktale, “Story of Understanding the Language of Beast” as well as the meaning of a marginal man conveyed in the folktale. First, among the characters that appear in the story, this study regarded a person who can understand the language of beasts as a marginal man, who is defined as “different” and excluded by most people. However, these kinds of people candidly speak about their power and seem confident about their identity. Meanwhile, they do not consider themselves as special or unusual in a way different from others but simply as a member living in the community together. This was examined as the reason they can be candid and confident. On the contrary, this study regarded the district magistrate and the husband as insiders who make up the majority of the community. The insiders push out people who are different from them, based on their common sense and experience, to the farthest outskirts of the community. The entities who define a marginal man judge right and wrong based on their common sense. By such judgment, the insiders in the end place people who are not congruent with their thoughts at the border of the community. In a word, prejudice of an individual or group is a factor that defines a marginal man. Also, from the behavior patterns of the folktale characters, this study questioned the standards by which a marginal man is defined and could confirm it is meaningless to divide insiders and marginal men. Because the standards defining a marginal man were subjective from the beginning, it was clearly shown that anyone can become a marginal man and an outsider according to such standards.

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