흰쥐의 혈관문합후 봉합재료에 따른 치유과정에 관한 실험적 연구

김승룡(Seung lyong Kim),신효근(Hyo Keun Shin) 대한구강악안면외과학회 1990 대한구강악안면외과학회지 Vol.16 No.2

The most important cause of failure of microvascular anastomosis is the thrombotic occlusion at the site of anastomosis. The purpose of this study was to compare the patency rates and healing process according to suture materials after microvascular anastomosis using femoral arteries of rats. The right femoral arteries were exposed and cut, and they were sutured with microsurgical instruments. The left femoral arteries served as controls. Experimental terms were 1 day, 2, 4, 7, 14, 21, and 28 days after surgery. Patency rates and changes in blood vessels in the anastomotic sites were examined using light microscope. The obtained results were as follows: 1. The total patency rate was 87.5%(21/24), and patency rate about nylon was 91.7%(11/12) and 83.3%(10/12) about silk. 2. The difference of healing process according to suture materials was not observed in this study. Further investigation with electron microscope may be necessary to find out the minute difference of healing process. 3. At the early stages, desquamation and disappearance of endothelial cells, exposure of internal elastic lamina, and rupture of part of the media were observed. Blood platelets and fibrins adhering to the same areas resulted in mural thrombi. 4. After 4 days of microvascular anastomosis, new endothelial cells were formed at some distant, undamaged luminal surface of blood vessel. At the same time, previously formed mural thrombi was decreased gradually. 5. Re-endothelialization was almost complete between 7 and 14 days. After 7 days microvascular anastomosis, thickening of the intimal layer between the endothelium and the internal elastic lamina was observed. The thickening was maximal at 21 days after denudation, after 21 days the thickness of the intima was decreased gradually. The thickened intimal layer was mainly composed of smooth muscle like cells.

滄江 金澤榮 연구의 현황과 과제

김승룡(Kim Seung-lyong) 한국인물사연구소 2006 한국인물사연구 Vol.5 No.-

항암화학요법을 시행 받은 암 생존자의 난소기능부전에 관한 연구

김영재 ( Kim Yeong Jae ),조삼현 ( Jo Sam Hyeon ),김승룡 ( Kim Seung Lyong ),조수현 ( Jo Su Hyeon ),김경태 ( Kim Gyeong Tae ),류기영 ( Lyu Gi Yeong ),유중배 ( Yu Jung Bae ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.5

목적 : 본 연구에서는 난소암으로 진단 받고 수태력유지를 위해 보존적 수술을 시행하고 보조 항암화학요법을 시행받은 가임기 여성에서 무월경기간을 통한 난소기능부전의 지속기간과 이후 임신여부를 후향적으로 연구하여 난소기능 부전의 위험인자로 생각되는 요인과 그 결과를 비교 분석해 보고자 하였다. 연구 방법 : 1985년부터 2001년까지 한양대학병원 부인과 병동에서 입원치료를 받은 난소암 환자 270명 중 보존적 수술에 이어 백금제제를 이용한 보조적 항암화학요법을 시행받은 환자로서 무병상태에 있는 환자 중 진단당시 나이 40세 미만의 환자 25명을 대상으로 하였다. 추적 검사는 이학적 검사 및 종양지표, 초음파검사 등을 사용하였으며, 무월경 기간 및 당시 연령, 호르몬제 투여에 따른 난소기능 회복기간 및 추후 성공적인 임신의 여부, 임신횟수, 출산횟수, 기형아출산 여부 등에 대해 조사하였다. 결과 : 대상으로 삼은 25명의 환자 중 이후 임신을 경험했던 환자들의 무월경 기간은 짧은 2.55개월로 대조군의 20.47개월에 비해 짧았으며, 항암화학요법의 평균 시행횟수는 6.45회와 6.33회로 큰 차이가 없었다. 또한 그 연령층에 있어서는 22.43세 및 22.9세로 유의한 차이는 없었다. 그러나 연령과 무월경기간, 항암화학오법 시행횟수와 무월경 기간에 있어서는 비례적 관계를 보였다. 임신을 경험한 군에서 만삭까지 임신을 유지한 경우는 전체 임신 9건 중 7건으로 22%의 유산율을 보였으며, 출산아에서 기형은 발견되지 않았다. 결론 : 이상의 결과로 치료 당시 나이가 많거나 항암화학요법의 시행횟수가 많을수록 무월경기간이 길어짐을 알 수 있었고, 이에 따라 난소기능부전의 정도도 심할 것을 추측할 수 있었다. Objective : We analysed the duration of ovarian dysfunction, amenorrhea and pregnancy rate of the patients who underwent the fertility preserving surgery and adjuvant chemotherapy at the reproductive age to identify the contributing factors of ovarian dysfunction and premature menopause. Methods : We select the 25 patients (<40 years old at diagnosis) among the 270 patients with malignant ovarian tumor who undergone conservative surgery and platinum-based adjuvant chemotherapy between the year 1985 and 2001. All patient was disease free state. Method used for follow up were physical exam, tumor markers and ultrasonography. We analysed age at diagnosis, amenorrheic period, recovery of ovarian function whether hormonal agent was used or not, times of pregnancy, times of successful pregnancy, and times of pregnancy outcome with anomaly. Results : In 25 cases, patients who became pregnant had a shorter period of amenorrhea of 2.55 months compared to 20.47 months of the rest. Total times (Kur) of chemotherapy shows no difference between two groups (6.45 vs 6.33). Average age show no differences between two groups (22.43 years vs 22.9 years), but amenorrheic period increased in proportion to age at treatment and times of chemotherapy, so we can guess that ovarian dysfunction is more serious with higher age at diagnosis and many times of chemotherapy. In the group who had been pregnant, successful outcome were 7 of 9 total times of pregnancy (abortion rate was 22%), and no baby had gross anomaly. Conclusion : So we can guess that ovarian dysfunction is more serious with higher age at diagnosis and more times of chemotherapy.

골격성 반대교합 환자의 악교정수술 전후 무성 마찰음 /s/, /∫/와 모음의 음향학적 특징 및 비음도의 변화

백은호(EunHo Baik),김승룡(Seung Lyong Kim),신효근(HyoKeun Shin) 대한치과의사협회 1998 대한치과의사협회지 Vol.36 No.9

자궁경부무력증 환자에서 복식자궁경협부원주봉합술 후 2차 임신에서의 예후

박민수 ( Park Min Su ),한현주 ( Han Hyeon Ju ),백지흠 ( Baeg Ji Heum ),김현희 ( Kim Hyeon Hui ),최중섭 ( Choe Jung Seob ),박문일 ( Park Mun Il ),황정혜 ( Hwang Jeong Hye ),김승룡 ( Kim Seung Lyong ),문형 ( Mun Hyeong ),정성로 ( J 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.12

목적 : 자궁경관무력증으로 진단받고, 이전에 질식자궁경부원주봉합술을 시행하여 임신 유지에 실패한 산모와 질식자궁경부원주봉합술을 시행할 수 없는 자궁경부를 가진 산모들에게서, 복식자궁경협부원주봉합술을 하여 분만 후 매듭을 제거하지 않을 시 향후 임신의 성공 및 예후를 알아보고자 한다. 연구 방법 : 1991년 5월부터 2002년 11월까지 복식자궁경협부원주봉합술을 시행하여 첫 번째 분만 후 매듭을 제거하지 않고 추적관찰시 향후 임신에 성공한 총 20예를 Objective : The purpose of this study was to investigate the effectiveness of further successful pregnancies and prognosis after delivery where the band was not removed from a transabdominal cervicoisthmic cerclage (TCIC) after a first successful pregnanc

흰쥐의 혈관 문합부 봉합재료에 따른 치유과정에 관한 실험적 연구

김승룡,김해인,박승오,신효근 全北大學校 齒醫學硏究所 1989 전북치대논문집 Vol.7 No.1

The most important cause of failure of microvascular anastomosis is the thrombotic occlusion at the site of anastomosis. The purpose of this study was to compare the patency rates and healing process according to suture materials after microvascular anastomosis using femoral arteries of rats. The right femoral arteries were exposed and cut, and they were sutured with microsurgical instruments. The left femoral arteries served as controls. Experimental terms were 1 day, 2,4,7,14,21, and 28 days after surgery. Patency rates and changes in blood vessels in the anastomotic sites were examined using light microscope. The obtained results were as follows : 1. The total patency rate was 87.5%(21/24), and patency rate about nylon was 91.7%(11/12) and 83.3%(10/12) about silk. 2. The difference of healing process according to suture materials was not observed in this study. Further investigation with electron microscope may be necessary to find out the minute difference of healing process. 3. At the early stages, desquamation and disappearance of endothelial cells, exposure of internal elastic lamina, and rupture of part of the media were observed Blood platelets and fibrins adhering to the same areas resulted in mural thrombi. 4. After 4 days of microvascular anastomosis, new endothelial cells were formed at some distant, undamaged luminal surface of blood vessel. At the same time, previously formed mural thrombi was decreased gradually. 5. Re-endothelialization was almost complete between 7 and 14 days. After 7 days of microvascular anastomosis, thickening of the intimal layer between the endothelium and the internal elastic lamina was observed. The thickening was maximal at 21 days after denudation, after 21 days the thickness of the intima was decreased gradually. The thickened intimal layer was mainly composed of smooth muscle-like cells

顎顔面骨 骨折患者의 臨床 統計的 硏究

진우정,김오환,김승룡,신효근 大韓顎顔面成形外科學會 1989 Maxillofacial Plastic Reconstructive Surgery Vol.11 No.1

This is a retrospective study on maxillofacial fractures. This study was based on a series of 442 patients with maxillofacial fractures treated at Dept. of oral and Maxillofacial Surgery, College of Dentistry, Chon Buk National University from Jan, 1984 to Sep. 1988. The results obtained were as follows: 1. The ratio of Male/Female was 4.8 : 1, and 3rd decade (43.9%) was the highest age group in incidence. 2. Monthly incidence was the highest in Oct,(10.6%). 3. The most frequent maxillofacial fracture site was mandible (70.0%), and zygoma & zygomatic arch (13.6%), maxilla(11.7%) and nasal bone (4.7%) were next in order of frequency. 4. Traffic accidents (47.5%), fight(24.8%) were the most common causes of maxillofacial fractures. 5. The most frequent chief complaint was painful swelling(40.7%). 6. In mandibular fractures, the most frequent fracture site was symphyseal area(28.9%) and simple fracture was the most frequent in type of fracture (71.2%). 7. In maxillary fractures, fracture with other facial bones (64.5%) was more frequent than fracture of maxilla only. The most common type of fracture was unilateral fractures(37.1%). 8. In fracture of zygoma complex, zygoma fracture was the most frequent fracture type(40.3%), zygoma and zygomatic arch fx,(30.6%), zygomatic arch fx(29.1%) were next in order 9. Open reduction was major method of treatment in maxillofacial fractures: Mandible(77.5%), Maxilla(61.3%), Zygoma complex(43.1%). 10. Maxillofacial fractures were most frequently combined with head injury(39.3%), and lower extremities(17.0%), upper extremities(13.6%) were next in order.