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Seong Hun Kim,Soo Teik Lee,Byung Jun Jeon,In Hee Kim,Sang Wook Kim,Seung-Ok Lee,김대곤,Ho Sung Park 대한소화기내시경학회 2012 Clinical Endoscopy Vol.45 No.4
A submucosal gastric adenocarcinoma, especially the signet ring cell type, is rare. The histologic evaluation techniques for this lesion has not been established; however, histologic confirmation is very important for decision of treatment method. Here, we report a 57-year-old man with a 12-cm gastric submucosal signet ring cell type adenocarcinoma, diagnosed by an endoscopic ultrasound-guided Trucut biopsy and immunochemical studies. This case suggests that the endoscopic ultrasound-guided Trucut biopsy might be a useful diagnostic method in cases of gastric adenocarcinoma with features of gastrointestinal stromal tumor.
라미부딘 내성이 발생한 만성 B형간염에서 아데포비어에 대한 초기 치료 반응이 아데포비어 내성 발생에 미치는 영향
김인희 ( In Hee Kim ),김성훈 ( Seong Hun Kim ),김현철 ( Hyun Chul Kim ),신경덕 ( Kyoung Deok Shin ),김상욱 ( Sang Wook Kim ),이승옥 ( Seong Ok Lee ),이수택 ( Soo Teik Lee ),김대곤 ( Dae Ghon Kim ) 대한간학회 2007 Clinical and Molecular Hepatology(대한간학회지) Vol.13 No.3
증례 : 활동성 크론병 환자에서 발생한 감염성 심내막염 1예
안철민 ( Chul Min An ),김성훈 ( Seong Hun Kim ),김인희 ( In Hee Kim ),김상욱 ( Sang Wook Kim ),이승옥 ( Seung Ok Lee ),이수택 ( Soo Teik Lee ),김대곤 ( Dae Ghon Kim ) 대한내과학회 2007 대한내과학회지 Vol.72 No.4
저자들은 활동성 크론병으로 치료 중인 22세 남자 환자로서 발열 기침을 주소로 내원하여 경험적 항결핵제와 항생제 치료 중 발생한 감염성 심내막염을 경험하였기에 문헌고찰과 함께 보고하는 바이다. Crohn`s disease is a condition of chronic inflammation potentially involving any location of the alimentary tract, from the mouth to the anus. Numerous extraintestinal manifestations also may be present. Inflammatory bowel disease may be considered an independent risk factor for infective endocarditis. Reasons for endocarditis may be more frequent bacteremia because of the higher incidence of diagnostic and therapeutic interventions, as well as an increased permeability of the damaged mucosa for bacteremia and therapeutic immunosuppression in patients with active inflammatory bowel disease. We report here a case of a 22-year old male who was diagnosed with infective endocarditis in active Crohn`s disease. This is the first case report in Korea of this diagonsis. (Korean J Med 72:420-425, 2007)
증례(症例) : 자발성 점막하 식도 박리 증례의 경과에 따른 영상소견과 문헌고찰
나영균 ( Young Gyun Na ),유창우 ( Chang Woo You ),정혜진 ( Hey Jin Jeong ),김성훈 ( Seong Hun Kim ),김인희 ( In Hee Kim ),이승옥 ( Seung Ok Lee ),김상욱 ( Sang Wook Kim ),김대곤 ( Dae Gohn Kim ),이수택 ( Soo Teik Lee ) 전북대학교 의과학연구소 2007 全北醫大論文集 Vol.31 No.1
Spontaneous intramural esophageal dissection is a rare disorder characterized by a lengthy laceration between the mucosal and submucosal layers of the esophageal wall, without perforation. Most spontaneous intramural esophageal dissection responds to conservative management, and usually it dose not lapse into a long protracted course of dealing with sequelae. We experienced a patient who complaints dysphagia and diagnosed as spontaneous intramural esophageal dissection. We managed him with conservative treatment and follow up endoscopy and other diagnostic tests for 3 weeks.
췌장질환에서 점액단백 항원 발현에 대한 면역 조직학적 연구
김용성 ( Yong Song Kim ),이승옥 ( Seung Ok Lee ),이수택 ( Soo Teik Lee ),김대곤 ( Dae Ghon Kim ),안득수 ( Deuk Soo Ahn ),강명재 ( Myung Jae Kang ) 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-
<목적> 점액 단백질(이하, Mucin)은 고분자량의 당단백질로서 소화기관 점막, 호흡기 점막 등에서 분비되어 점막선관을 윤활하고 보호하는 작용을 할 뿐아니라 세포증식 및 면역반응을 조절하는 기능을 가진다고 알려져 왔다. 지금까지 밝혀진 연구에 따르면 모두 8종류의 Mucin이 존재한다고 알려져 있는데 이들 기관이 병적인 상태로 변화하면 점액의 생성과 분비에 변화가 나타날 뿐 아니라 점액 유전자의 발현에도 변화가 나타난다고 알려져 있다. 본 연구에서는
간경변증에서 잔존 간기능을 나타내는 지표: Apolipoprotein A-I
이승룡 ( Seung Young Lee ),김소영 ( So Young Kim ),안득수 ( Deuk Soo Ahn ),이수택 ( Soo Teik Lee ),김대곤 ( Dae Kon Kim ) 전북대학교 의과학연구소 2005 全北醫大論文集 Vol.29 No.2
Background: Apolipoprotein A-I (Apo A-I), a 28 kd protein, is synthesized mainly by hepatocytes. It is decreased in alcoholic patients with liver fibrosis and cirrhosis. The mechanisms of serum apo A-I decrease in liver cirrhosis are unknown, but it has been shown that serum apo A-I measurement alone or in correlation with other biological data such as prothrombin time and r-glutamyl transferase, albumin and total bilirubin can serve as a marker of liver cirrhosis in alcoholic patients. Material and prupose: This study of apo A-I has been undertaken in 201 patients of liver cirrhosis and 138 patients of hepatocelluar carcinoma in order to describe the change of apo A-I according to dfferent stages of the liver cirrhosis, to correlate the changes to serum liver function tests and to estimate its diagnosis, prognostic values and functional reserve of injuried liver. Results: Results showed that apo A-I concentration is highly related to the degree of liver injury, reaching a minimum in patients with severe cirrhosis (Child-Pugh classification C). And apo A-I is correlated with biological marker of liver function such as albumin, prothrombin time, total bilirubin, a2-macroblobuiln. This is showed that apo A-I had an independent and discriminative value for the diagnosis of cirrhosis. This result was showed not only in patients of alcoholic liver cirrhosis but also in patients of hepatocelluar carcinoma due to hepatitis B. Conclusion: Our results suggest that serum Apo A-I is index for functional reserve in the irreversible liver disease such as cirrhosis of liver and hepatocelluar carcinoma.
송항용(Hang Yong Song),이경석(Kyung Suk Rhee),이수택(Soo Teik Lee),김대곤(Dae Kon Kim),안득수(Deuk Soo Ahn) 대한소화기학회 1995 대한소화기학회지 Vol.27 No.1
N/A Background/Aims: Clonorchis sinensis, the Chinese liver fluke, is an important human parasite and is widely distributed in Southern Korea, China, Taiwan, Japan and Eastern Asia. Methods: To understand the more extensive clinical feature of clonorchiasis, we carried out an investigation retrospectively for hematology, blood biochemistry, clinical symptoms, and radiologic findings on a total of 309 clonorchiasis patients whose stools were positive for eggs of clonorchis sinensis at Chonbuk univeristy hospital. Results: 309 patients(270 males and 39 females) aged between 18 and 78 years. Common symptoms were right upper quadrant pain in 43 cases(13.9%), generalized weakness in 39 cases(12.6%), and jaundice in 39 cases(12.6%), and hepatomegaly in 25 cases(8%). 87 out of 250 cases(34.8%) showed normal eosinophilic count. The level of ALT was normal in 237 out of 303 cases(78.2%). The patients with more than 101 unit of ALT were 35 out of 303 cases(11.6%). In 131 patients among 275 cases, alkaline phosphatase value were in the normal limit(47.6%). As for ultrasonography, we couldnt find out abnormal findings in 62 out of 122 cases(51.8%). But 16 out of 122 cases(13.1%) showed the peripheral intrahepatic duct dilatation. And 14 cases(11.5%) showed the echoes of worms of clonorchiasis in the gall bladder. In 11 out of 46 cases(32.4%), abdominal CT showed diffuse dilatation of the periphera1 bile ducts. In 57 out of 81 patients(70.4%), there were positive reaction in intradermal test for clonorchis sinensis. And they had cross reaction with paragonimiasis in 23 out of 81 cases(28.4%). Conclusions: In the view of the results so far achieved, the result of our investigation is wide difference acompared with others report for clonorchiasis. We thought this difference is probably due to include more lightly infected persons by clonorchis sinensis in our .tudy group. So we suggest, to understand the clinical manifestation of clonorchiasis, it is necesssary to carry out examination for ultrasonography, abdominal CT and laboratory finding of patients depend on the number of worms, infection period, intensity and complication. (Korean J Gastroenterol 1995;27:64-71)
이길홍 ( Kil Hong Lee ),마명신 ( Myung Sin Ma ),이승옥 ( Seung Ok Lee ),이정민 ( Jeong Min Lee ),이수택 ( Soo Teik Lee ),김대곤 ( Dae Ghon Kim ),안득수 ( Deuk Soo Ahn ) 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-
<Background/Aims> To describe the treatment efficacy and safety of radiofrequency ablation (RFA) to treat hepatocellular carcinoma (HCC) and metastatic liver tumors. Most patients with HCC are not candidates for resection because of multifocality, advance