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- 저자 : 권형철(Hyung Chul Kwon) (검색결과 6 건)
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Splenic Irradiation in Chronic Myeologenous Leukemia
오윤경,권형철,윤세철,박용휘,김춘추,김동집,Oh Yoon Kyeong,Kwon Hyung Chul,Yoon Sei Chul,Bahk Yong Whee,Kim Choon Choo,Kim Dong Jip The Korean Society for Radiation Oncology 1985 Radiation Oncology Journal Vol.3 No.2
전신질환인 만성골수성백혈병(Chronic Myelogenous Leukemia: CML)에 있어서, 비장에만 국소적으로 방사선을 조사(Splenic Irradiation; SI)함으로써, 임상적 증상의 호전과 혈액소견상에 완해를 일으킨다는 것은 1903년대 이후로 알러져 있는 사실이다. 최근에 와서 Busulfan에 의한 화학요법이 주치료로서 도입되기 전까지는 SI가 CML치료에 광범위하게 사용되어 왔었다. 요즈음엔 비장의 방사선치료는 화학요법보다 그 결과가 좋지 못하지만, 통증을 동반한 비종대에서 증상의 완화를 위하거나, 가속기(accelerated phase)에 들어섰거나, 화학요법에 반응하지 않을 때 사용되고 있다. SI의 효과는 백혈구수의 감소, 헤모글로빈치의 상승등의 직접, 간접효과가 있으며 이 효과는 방사선치료를 끝낸 후에도 어느 기간 지속되며, 만족스런 반응을 보일 경우엔 반복치료도 시도되고 있다. 그리고 약물치료에 반응이 없었던 판자에서도 에로는 SI로 임상적 호전을 관찰할 수 있으며, SI전에 많은 치료를 받지 않았던 경우에 더 좋은 반응을 기대할 수 있음은 잘 알려져 있다. 가톨릭의대 방사선치료실에서는 화학요법도중 통증을 동반한 심한 비종대를 호소하거나, 화학요법에 반응이 없었던 15례의 CML환자에서 SI를 실시하였다. 저자들은 대상환자들의 SI전후의 임상적 증상, 이학적 소견 혈액학적 소견등의 변화 및 생존기간을 추적하였기에 문헌고찰과 함께 보고하는 바이다. Radiation therapy was the treatment of choice for CML in the past, in the form of SI or radioactive phosphorus. Its use has been replaced to a large extent by various chemotherapeutic agents. Recently SI in CML has been used, both to relieve painful splenomegaly and to take advantage of an indirect effect of SI on unirradiated bone marrow. We have treated 15 CML cases who had a huge spleen during chemotherapy or even after chemotherapy by 6 MV linear accelerator during the past two years at the Division of Radiation Therapy, Kang Nam St. Mary's Hospital, Catholic College. Response to SI has been rated according to the scoring system of Roger W. Byhardt, et al. which evaluated the splenic and hematologic response as well as the response of disease-related systems. According to this scoring system, most patients demonstrated a significant relief of splenomegaly along with improvement of hemogram. And we observed the change of Karnofsky Performance Status after SI, and survival after a confirmative diagnosis and SI.
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윤세철(Sei Chul Yoon),권형철(Hyung Chul Kwon),오윤경(Yoon Kyeong Oh),박용휘(Yong Whee Bahk),손호영(Ho Young Son),강준기(Joon Ki Kang),송진언(Jin Un Song) 대한방사선종양학회 1985 Radiation Oncology Journal Vol.3 No.1
Twenty-four cases of pituitary adenoma, 13 males and 11 females with the age ranging from 11 to 65 years, received radiation therapy(RT) on the pituitary area with 6MV linear accelerator during past 25 months at the Division of Radiation Therapy, Kangnam St. Mary's Hospital, Catholic Medical College. Of 24 cases of RT, 20 were postoperative and 4 primary. To evaluate the effect of RT, we analysed the alteration of the endocrinologic tests, neurologic abnormalities, major clinical symptoms, endocrinologic changes and improvement in visual problems after RT. The results were as follows ; 1. Major clinical symptoms were headache, visual defects, diabetes insipidus, hypogonadisms and general weakness in decreasing order of frequency. 2. All but the one with Nelson's syndrome showed abnormal neuroradiologic changes in the sella turcica with an invasive tumor mass around supra· and para-sellar area. 3. Endocrinological classifications of the patient were 11 prolactinoma, 4 growth hormone -secreting tumors, 3 ACTH-secreting tumors consisting of one Cushing's disease and two Nelson's syndrome, and 6 nonfunctioning tumors. 4. Eleven of 14 patients, visual problems were improved after treatment but remaining 3 were unchanged. 5. Seven of 11 prolactinomas returned to normal hormonal level after postoperative and primary RT and 3 patients are being treated with bromocriptine (BMCP) but one lost case. 6. Two of 4 growth hormone·secreting tumor returned to normal level after RT but the remaining 2 are being treated with BMCP, as well.
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김정수,권형철,최기철 의과학연구소 1988 全北醫大論文集 Vol.12 No.1
Malignant melanoma arising in the mucosa of the head and neck region is an infrequently encounterd clinical entity. Computerized radiotherapy treatment planning combined with computerized tomographic scanning has improved accuracy and contributed greatly to the solution of complex treatment problems. A case of mucosal malignant melanoma arising in nasal cavity was treated with radiation therapy in aid of computerized radiotherapy treatment planning.
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김정수,권형철,홍기환 의과학연구소 1992 全北醫大論文集 Vol.16 No.1
Between 1985 and 1991, we treated 10 previously untreated patients with piopsy proven carcinoma of the nasopharynx by nagavoltage external radiation therapy to the primary site, base of the skull and both sides of the neck. Thirty percent of the patients had T4 primaries and seventy percent had stage Ⅳ disease. The pathology was squamous cell carcinoma in 6 patients and undifferentiated carcinoma in 3 patients and lymphoepithelioma in one patient. Seventy percent had complete remission in primaries and five patients had suffered from relapse of the carcinoma, all of them relapsed at distant sites. Median survival following relapse was 5 months.
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김종수,권형철,윤용주 의과학연구소 1990 全北醫大論文集 Vol.14 No.2
A detailed retrospective analysis of the results of treatment of glottic cancer is presented. Twelve patients were treated by curative radiation therapy at the Department of Therapeutic Radiology in Chonbuk National University Hospital between 1986 and 1989. All Patients had squamous cell cardinoma, half of them had well differentiated type. A month after radiation therapy, the complete remission rate was 90% in early glottic cancer and partical remission rate was 100% in advanced glottic cancer. The use of voice after radiation therapy and surgery is also discussed.
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