약용식물 추출물로부터 항상화활성 탐색

권지웅,이어진,김윤철,이혜숙,권태오 한국생약학회 2008 생약학회지 Vol.39 No.2

This study was carried out to search the natural antioxidants from the 36 medicinal plants. IC50 values of linoleic acid peroxidation inhibition to the BHA, BHT and α-tocopherol showed 7.2 μg/ml, 7.3 μg/ml, and 26.6 μg/ml, but hexane extract of Zingiber officinale showed 13.2 μg/ml, EtOAc extracts of Phellinus linteus, Morus alba, Zingiber officinale and butanol extract of Diospyros kaki showed 15.9 μg/ml, 16.9 μg/ml, 20.1 μg/ml, and 21.5 μg/ml respectively. IC50 values of DPPH radical scavenging activity of BHA, BHT and α-tocopherol showed 14.9~27.7μg/ml, but EtOAc extract of Paeonia suffruticosa showed the lowest 6.5 μg/ml than those of other extracts, EtOAc extracts of Camellia sinensis, Salvia miltiorrhiz, and Phellinus linteus showed 8.0 μg/ml, 11.5 μg/ml, and 13.0 μg/ml respectively

Pyogenic Vertebral Osteomyelitis: Clinical Features, Diagnosis, and Treatment

권지웅,현승재,한상현,김기정,장태안 대한척추신경외과학회 2017 Neurospine Vol.14 No.2

Pyogenic vertebral osteomyelitis (PVO) may result in neurological deficits and sequelae, so early diagnosis and appropriate treatment are critical. Many previous studies on PVO exist, but our paper has aimed to comprehensively summarize the clinical aspects of PVO. Through review of the vast literature on the clinical research of PVO an overview of the clinical characteristics, diagnostic methods, treatment and prognosis is provided.

메타경로분석을 이용한 미시체계 내 방어행동 관련 요인 간의 구조적 관계

권지웅,박종효 한국열린교육학회 2022 열린교육연구 Vol.30 No.3

In this study, from the point of view of the ecological systems model, meta path analysis was performed on the correlations among the peer relationships, anti-bullying, school culture, and social-emotional competence in the micro-system. Through this, we suspected the significance of direct and indirect effects between the factors in the path towards defending behaviors, by anti-bullying school culture and peer relationships, environmental variables, mediating social emotional competence, and personal variables. To do this, the meta-path analysis was conducted on domestic academic journals (33 articles), master's and doctoral dissertations, and candidate journals (29 articles) from January 2007 to June 2021 (total 62 articles). In the meta path analysis, direct effects were found in all paths among all factors of the peer relationships, anti-bullying school culture, social-emotional competence, and defending behaviors. In addition, mediating effects were found in social emotional competence factors between peer relationships and defending behaviors, and between the anti-bullying school culture and defending behaviors respectively. As a result of this, it is implied that students who develop a high level of social-emotional competence based on their peer relationships and anti-bullying school culture tend to show a higher frequency of defending behaviors in school violence environments. 본 연구는 생태체계 모형의 관점에서 방어행동 관련 주요 요인으로 알려진 미시체계 내 또래관계, 비폭력학교문화, 사회·정서역량 요인과 방어행동의 관계를 메타경로분석으로 살펴보았다. 이를 통해 환경 변인인 또래관계, 비폭력학교문화가 개인 변인인 사회·정서역량을 매개하여 방어행동에 도달하는 경로에서 각 요인 간 직·간접효과가 유의한지를 확인하는 데 목적이 있다. 이를 위하여 2007년 1월부터 2021년 6월까지 국내에서 진행된 학술지(33편) 및 석·박사 학위 논문(29편)을 대상으로 총 62편의 연구물을 분석에 활용하였다. 분석 결과는 또래관계, 비폭력학교문화, 사회정서역량, 방어행동은 모든 요인 간 경로에서 직접 효과가 나타났다. 또한 또래관계, 비폭력학교문화와 방어행동과의 관계에서 사회·정서역량은 모두 매개효과를 보였다. 이런 결과로 볼 때 또래관계가 좋고 학교문화를 비폭력적이라고 인식하는 학생들은 사회·정서역량을 통하여 방어행동의 빈도가 높아짐을 확인할 수 있었다.

초․고등학생의 또래지위가 방어행동에 미치는 영향: 다층수준모형을 이용한 학교급 및 학급 수준의 괴롭힘대처집단효능감의 조절효과

권지웅,박종효 한국교육심리학회 2020 敎育心理硏究 Vol.34 No.2

The purpose of this study is to identify the moderating effect of classroom-level collective efficacy on coping against bullying and school-level by using multi-level analyses on the relationship between peer status (i.e., social preference, popularity) and defending behavior. The fourth wave of ClassNet with a set of cross-sectional data were used where a total of 2,197 students (61 elementary school classes and 35 high school classes) participated. Self-reported measures measured the collective efficacy of coping against bullying and pro-social behavior, and preference, popularity, and defending behavior were measured by peer nomination. The significant findings were as follows: First, the average levels of collective efficacy for coping against bullying and defending behavior were significantly higher among elementary school students than high school students, In contrast, the mean scores of pro-social behavior and social preference were substantially higher among high school students than elementary school students. Second, defending behavior (ICC, 59.0%) differed greatly in classes. Third, social preference and popularity significantly and positively influenced on defending behavior. Fourth, compared to high school classrooms, popularity, and social preference had a more significant impact on increasing defending behaviors in elementary school classrooms. Fifth, popularity and social preference had a greater effect on defending behavior in classrooms with higher levels of collective efficacy to coping against bullying efficacy rather than in lower levels of one. These moderating effects remained significant after controlling for individual-level covariates (i.e., social preference, popularity, pro-social behavior, gender). Finally, we discussed the educational implications of shaping classroom culture to promote collective efficacy in coping against bullying for students with high levels of popularity and social preference to defend bully victims more frequently actively. 본 연구는 다층수준분석을 이용하여 또래지위(선호, 인기)와 방어행동의 관계에서 학교급과 괴롭힘대처집단효능감의 조절효과를 확인하였다. 본 연구에서 사용된 자료는 클래스넷 4차년도 횡단 데이터 자료의 일부로서, 전국 소재의 초등학교 61학급, 고등학교 35학급 총 2,197명을 대상으로 하였다. 본 연구의 변인들은 자기보고방식으로 측정한 괴롭힘대처집단효능감과 친사회적행동과 또래지명 방식으로 측정한 선호와 인기, 방어행동으로 구성되어 있다. 본 연구에서는 다음과 같은 결과를 얻었다. 첫째, 괴롭힘대처집단효능감과 방어행동의 평균은 초등학교가 고등학교 보다 통계적으로 유의한 수준으로 높았으며, 친사회적행동과 선호의 평균은 고등학교가 초등학교 보다 통계적으로 유의하게 높았다. 둘째, 학생 개인 수준의 선호와 인기는 각각 방어행동에 유의한 영향을 미쳤다. 또한 초등학교는 고등학교보다 선호 및 인기가 방어행동에 미치는 수준을 더 유의하게 높였다. 셋째, 개인변인인 친사회적행동이 방어행동에 미치는 영향력을 엄밀하게 통제한 후에도 학급 수준인 괴롭힘대처집단효능감은 또래지위(선호, 인기)가 방어행동에 미치는 수준을 유의하게 상승시켰다. 마지막으로 또래지위가 높은 학생들이 또래괴롭힘을 예방할 수 있는 방어행동을 더 자주 행사하기 위해서는 괴롭힘대처집단효능감을 증진시키는 학급 문화의 형성과 함께 해당 변인에 대한 프로그램 개발 및 시행이 중요하다는 시사점에 대해 논의하였다.

복분자 에탄올 추출물의 생리활성 탐색

권지웅,이희권,박희전,권태오,최혜란,송지영 한국약용작물학회 2011 한국약용작물학회지 Vol.19 No.5

This study was carried out to evaluate biological activities to different ethanol extracts from unripened and ripened fruit (Rubus coreanus Miq.). 25% to 75% ethanol extracts of unripened and ripened fruits were similar to extract yield respectively. Yield of ethanol extract of ripened fruit were approximately 3 times higher than that of unripened fruit. 75% ethanol extract of unripened fruit showed the highest contents of total polyphenol (180.04±0.41 mg/g) and total flavonoid (50.43±0.81 mg/g). Contents of total polyphenol and total flavonoid of unripened fruit were about 2 times higher than those of ripened fruit. IC50 values of DPPH radical scavenging activity and linoleic acid peroxidation inhibition activity of BHA and α-tocopherol showed 13.19±0.21 and 18.16±0.23μg/ml, 4.25±0.04μg/ml and 5.56±0.10μg/ml respectively, but 75% ethanol extract of unripened fruit showed the lowest 23.85±0.10μg/ml and 7.34±0.07μg/ml among other all extracts. IC50 values of LDL (low density lipoprotein) oxidation inhibition activity and α-glucosidase inhibitory activity of 75% ethanol extract of unripened fruit showed the lowest 1.04±0.04μg/ml and 7.21±0.13μg/ml among other all extracts respectively. Specifically, 75% ethanol extract of unripened fruit has relatively better biological activities than other ethanol extracts, it could be potentially used as bioactive source for health functional foods.

학교공동체의식, 또래관계, 사회⋅정서역량과 방어행동 간의 초⋅중등 다집단 메타경로분석

권지웅,박종효 학습자중심교과교육학회 2022 학습자중심교과교육연구 Vol.22 No.13

Objectives The current study aimed to explore the relationship between a person and its embedded ecological systems using multi-group (primary vs. secondary) meta-path analysis. Through this, the significance of the indirect effect of social-emotional competence was determined in the path model of connecting environmental variables of sense of school community and peer relationship to defending behavior. Finally, we tested whether the mediating effect of social-emotional competence in the entire group differed by school level (primary vs. secondary). Methods A multi-group meta-path analysis was conducted on domestic academic journals (29 articles), master's and doctoral dissertations, and candidates for entry journals (28 articles) from 2007 to June 2021. Two-step processes were performed for meta-path analysis (a) the mean correlation coefficient, that is, a pooled correlation matrix was obtained using the random effect model for the correlation between each study, and (b) direct and indirect effects were examined using meta-path analyses. Results In the meta-path analysis for entire and middle school students, direct and indirect effects were significant in all paths among the sense of school community factor, the peer relationship factor, the social-emotional competence factor, and the defending behavior factor. However, in elementary school students, social-emotional competencies mediated fully the relationship between the sense of school community and defending behavior. Still, social-emotional competence did not mediate the relationship between peer relations and defending behavior. Conclusions This study confirmed that elementary and middle school students had different pathways in the model in which sense of school community and peer relationship impacted the defending behavior through individual social-emotional competence. 목적 본 연구는 또래괴롭힘 방어행동 요인에 영향을 미치는 주요 변인으로 채택된 생태체계와 개인 간의 관계를 규명하고자 초⋅중등 전체와 함께 학교급 별로 다집단 메타경로분석을 실시하였다. 이를 통해 환경 변인인 학교공동체의식, 또래관계가 개인 변인인사회⋅정서역량을 매개하여 방어행동에 이르는 경로에서 각 요인 간 직접효과의 유의성을 살펴보았다. 마지막으로 생태체계 요인과 방어행동의 관계에서 개인이 학교급에 따라 매개효과 차이가 있는지를 살펴보고자 하였다. 방법 이를 위해 2009년부터 2021년 6월까지 국내에서 진행된 학술지(29편) 및 석⋅박사 학위 논문 및 등재후보지를 대상으로(28 편) 다집단 메타경로분석을 실시하였다. 메타경로분석의 순서는 각 연구 간의 상관을 랜덤효과모형을 이용해서 평균 상관값인 합동상관행렬을 구한 후 이를 경로분석의 방법을 이용하여 직⋅간접효과를 살펴보았다. 결과 전체와 중등 집단을 대상으로 한 메타경로분석은 학교공동체의식 요인, 또래관계 요인, 사회⋅정서역량 요인, 방어행동 요인간 모든 경로에서 직⋅간접 효과가 모두 나타났다. 하지만 초등집단에서는 학교공동체의식과 방어행동의 관계에서 사회⋅정서역량은 완전매개효과를 나타냈지만 또래관계와 방어행동의 관계에서는 사회⋅정서역량이 매개효과를 나타내지 않았다. 결론 본 연구는 학교공동체의식과 또래관계라는 환경적 요인이 개인의 사회⋅정서역량을 거쳐 방어행동을 일으키는데 있어 초등과중등학생이 경로 차이가 남을 확인하였다.

다층 구조방정식을 이용한 초등학생의 학급 공동체 의식 및 또래지위와 방어행동의 관계에서 친사회적 행동의 매개효과

권지웅(Kwon, Ji-Woong),박종효(Park, Jong-Hyo) 한국교육심리학회 2021 敎育心理硏究 Vol.35 No.1

본 연구는 초등학교 4, 5, 6학년 1,374명의 학생들(남 50.0%)을 대상으로 ‘학급 공동체 의식’ 및 ‘또래지위’와 ‘방어행동’의 관계에서 작용하는 ‘친사회적행동’의 매개효과를 학생 및 학급 수준에서 확인하고자 하였다. 연구 문제 검증을 위하여 클래스넷 데이터(4차년 1차)를 사용하였다. 학급 공동체 의식과 친사회적 행동은 자기보고 방식으로 측정하였고, 또래지위와 방어행동은 또래지명 방식으로 측정하였다. 다층 구조방정식을 이용하여 분석한 결과는 다음과 같다. 첫째, 학급과 학생 수준 모두 학급 공동체 의식은 친사회적 행동에 정적인 직접 효과를 보였고, 또래지위도 방어행동에 정적인 직접 효과를 보였다. 둘째, 학생 수준에서 또래지위는 친사회적 행동과 방어행동에 정적인 직접 효과를 보였다. 셋째, 학생 수준에서 학급 공동체 의식은 방어행동에 부적인 직접 효과를 보였고 친사회적 행동은 정적인 직접 효과를 보였다. 넷째, 학생 수준에서 친사회적 행동은 학급 공동체 의식과 방어행동 간의 관계에서 부분적으로 매개하는 간접 효과를 보였다. 마지막으로, 학생 수준에서 친사회적 행동은 또래지위와 방어행동 간의 관계에서 부분적으로 매개하는 간접 효과를 보였다. 이런 결과로 볼 때 학급 수준에서 평균적으로 방어행동 비율이 높은 학급은 평균적으로 또래지위가 높은 학생들로 구성되어 있음을 알 수 있으며, 학생 수준에서 학급 공동체 의식과 또래지위가 높은 학생들의 방어행동 역량을 키우기 위해서는 친사회적 행동을 거쳐야 한다는 시사점을 확인할 수 있었다. The purpose of this study is to identify the mediating effect of pro-social behavior in the relationships among sense of class community, peer status, and defending behavior in 1,374 elementary school children (including 50% boys) of the fourth, fifth and sixth grades. The Class-Net (4th wave) data were used to empirically test the research model. Sense of class community and pro-social behavior were measured using a self-report method, whereas defending behavior was assessed using a peer nomination method. The multi-level structural equation modeling (MSEM) analysis revealed the following. First, sense of class community, at both student and class levels, had a positive direct effect on pro-social behavior, and peer status had a positive direct effect on defending behavior. Second, peer status at the student level had a positive direct effect on pro-social and defending behaviors. Third, sense of class community at the student level had a negative direct effect on defending behavior, whereas pro-social behavior had a positive direct effect on defending behavior. Fourth, sense of class community had an indirect partial mediation effect on defending behavior via pro-social behavior at the student level. Finally, pro-social behavior at the student level had an indirect partial mediation effect in the relationship between peer status and defending behavior. Based on these results, it can be concluded that a class with a high ratio of defending behavior consists of students with high peer status at the class level. Moreover, the results of this study suggest that students who have high levels of both “sense of class community” and “peer status” are encouraged to display pro-social behaviors in the classroom in order to play an active role as defenders against peer victimization.

새로운 가족, 새로운 주거 그리고 공유주택에 대해서

권지웅(Kwon, Ji-Woong) 대한건축학회 2016 建築 Vol.60 No.6

이중호박사 정년퇴임 기념논문집 : 스테비아로부터 천연 제초 활성물질의 분리 및 동정

권지웅 ( Ji Wung Kwon ),이중호 ( Joong Ho Lee ),이동헌 ( Dong Heon Lee ),권태오 ( Tae Oh Kwon ),김용현 ( Yong Hyun Kim ),노정래 ( Jung Rae Rho ),채규윤 ( Kyu Yoon Chai ) 원광대학교 생명자원과학연구소 2004 생명자원과학연구 Vol.27 No.1

연구논문 : 추출방법에 따른 복분자 추출물의 생리활성

권지웅 ( Ji Wung Kwon ),이희권 ( Hee Kwon Lee ),박희전 ( Hee Jeon Park ),송지영 ( Ji Young Song ) 한국식품조리과학회(구.한국조리과학회) 2012 한국식품조리과학회지 Vol.28 No.1

This study was carried out to evaluate biological activities concerning extracts according to extraction methods from unripened fruit of Rubus coreanus Miq. The extraction methods were HWE (hot water extraction for 4 hr at 100℃), SFE (extraction for 3 hr at 40℃ under 300 bar, 100% of CO2 fluid), USE (ultrasonification extraction for 4 hr at 50℃ with water), USE+HWE (hot water extraction for 2 hr at 100℃ after ultrasonification process for 2 hr), VE (vacuum extraction for 4 hr at 90℃ under 0.9 bar with water). VE extract showed the highest contents of total polyphenol (178.78±3.79 mg/g) and total flavonoid (40.93±0.68 mg/g). IC50 values of DPPH radical scavenging activity, linoleic acid peroxidation inhibition activity and LDL (low density lipoprotein) oxidation inhibition activity of HWE extract showed the lowest 35.39±0.25 μg/mL, 12.61±0.31 μg/mL and 1.31±0.02 μg/mL among other all extracts, respectively. IC50 values of α-glucosidase inhibitory activities of VE and HWE extracts showed lower 14.34±0.20 μg/mL and 15.83±0.20 μg/mL than those of other extracts, respectively. Specifically, HWE and VE extracts have relatively better biological activities than other extracts; these could be potentially used as a bioactive source for health functional foods.