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전신성 홍반성 루푸스 환자에서 발생한 전신 피하조직 석회화
권기민 ( Ki Min Kwon ),박재호 ( Jae Ho Park ) 대한류마티스학회 2000 대한류마티스학회지 Vol.7 No.1
Systemic lupus erythematosus (SLE) is a disease of unknown etiology in which tissues and cells are damaged by pathogenic autoantibodies and immune complexes. Skin manifestations of SLE include malar rash, discoid rash, photosensitivity, oral ulcer, panniculitis, urticaria, bullae, erythema multiforme and lichen planus-like lesions. It has long been recognized that dystrophic soft tissue calcification may occur in association with certain connective tissue disorders such as scleroderma or dermatomyositis. Soft tissue calcification in a patient with SLE has been rarely reported. We have experienced a patient with SLE who presented with diffuse subcutaneous tissue calcification on face, chest, abdomen and all extremities.
갑상선 호르몬의 자가항체에 의한 갑상선 호르몬(T3)의 비정상적인 상승의 1례
이인규,류성열,권기민,황준영,이상준,신동우 啓明大學校 醫科大學 1999 계명의대학술지 Vol.18 No.4
Anti-thyroid hormone autoantibodies were reported in the Hashimoto's thyroiditis, Graves' disease, thyroid cancer and other thyroid diseases. Most of these autoantibodies are IgG. Immunologically, the thyroid hormone can be considered hapten and as such are unable to induced antibody production. But thyroid hormone can present to the immune system when this hapten is coupled with carrier protein such as thyroglobulin. Anti-thyroid hormone autoantibodies in serum will give falsely high or low thyroid hormone values in radioimmunossays. When the methods based upon absorption of free thyroid hormone or precipitation of all hormone-antibody complex are used, low values in favor of hypothyroidism will be found, whereas high values will be obtained with double-antibody of solid-phase technics. When these autoantibodies bind with thyriod hormone, abnormal elevation or decreased titers of thyroid hormone is seen in radiommunoassay. The interference gives clinicians inappropriate information about the patient's thyroid status. As a result, patients may receive unnecessary treatment from physicians who are unaware of the presence of the autoantibody. We report a case of abnormal elevation of T3 and TSH by anti-T3 autoantibodies in the serum of hypothyroid patient with Hashimoto's thyroiditis.
전신성 홍반성 루푸스 환자에서 발생한 재발성 다발성 연골염
김병상,김현철,권기민,박재호,도주호,권두영 啓明大學校 醫科大學 1999 계명의대학술지 Vol.18 No.4
Relapsing polychondritis is an episodic and often progressive inflammatory disorder of unknown cause affecting predominantly the cartilage of ears, nose and tracheobronchial tree as well as other proteoglycan-rich structures such as eye, heart, blood vessels and inner ear. Relapsing polychondritis can present with many other rheumatic disorders, such as rheumatoid arthritis, systemic lupus eryhematosus, Sjogren's syndrome, Behcet's disease and vasculitis. Recently we have experienced a case of relapsing polychondritis patient who presented with systemic lupus erythematosus. Relapsing polychondritis occuring in a systemic lupus erythematosus patients have never been reported in the Korean literature.
김상현,김기영,박재호,김혜순,박승국,윤상미,박근규,권기민,도주호,황준영 대한내과학회 2000 대한내과학회지 Vol.59 No.5
Bypass surgery, as therapy for morbid obesity, was introduced in 1952. Multiple complications such as arthritis and dermatitis as well as liver dysfunction, renal injury, diarrhea, malnutrition and electrolyte imbalance were reported after bypass surgery. Recently, we have experienced a case of bypass arthritis-dermatitis syndrome in a patient after pyloric exclusion and bypass gastrojejunostomy due to traumatic duodenal perforation. He complained arthralgia of left knee, both wrist and both ankle and developed erythematous maculopapular rash over lower extremities. He was successfully treated with NSAIDs and clindamycin.(Korean J Med 59:583-586, 2000)