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곽성재 대한양계협회 1987 월간 양계 Vol.19 No.10
배합사료 가격 등락의 움직임이 심심치않게 거론되고 축협은 사료가격을 인하했다. 앞으로의 축산$\cdot$ 사료산업은 공히 막연한 수요기대 속에서의 공급기반 확대노력은 지양되어야 할 것이며, 산업의 질적$\cdot$내적인 면에서의 국제경쟁력 강화를 위한 정책적인 배려가 있어야 할 것이다.
박수현,김형건,곽성재,손태경,김삼,박경창,육청미 대한내과학회 2001 대한내과학회지 Vol.61 No.1
Colonic lipomas represent the most frequent mesenchymal benign tumors of the large intestine after hyperplastic polyps and adenomatous polyps, but the pathogenesis is unclear. These tumors are composed of mature fatty tissue and usually arise in the submucosa. They are usually solitary and small, and may be sessile or pedunculated. Most patients are asymptomatic and their tumors are often detected incidentally, but tumors larger than 2 cm tend to produce change in bowel habit, abdominal pain, rectorrhagia and complications such a luminal obstruction or intestinal intussusception. Diagnosis may be aided by colonoscopy with biopsy, barium enema and computed tomography. Colonic lipomas occur most often in the right colon, particularly in the ileocecal valve. Some cases of such lipoma of transverse colon have been reported in Europe and the United States, but rare in Korea. We report a case of lipoma of the transverse colon that was originated in subserosa and presented as a intussusception in a 63-year-old woman with brief review of literatures. (Korean J Med 61:41-45, 2001)
김우중,이명석,김형건,오흥영,곽성재,권성희,여미애,이경원 대한소화기학회 2000 대한소화기학회지 Vol.35 No.6
Tuberculosis of the liver is uncommon. Subsequent development of jaundice during antituberculous chemotherapy is usually caused by the side effects of drugs. The case of obstruction of the extrahepatic biliary system by tuberculous lymphadenopathy causing obstructive jaundice is extremely rare. A 18- year-old man was admitted to the hospital due to jaundice. He had the medical history of tuberculous pleurisy treated by antituberculous chemotherapy for about 4 months. Abdominal ultrasonography and computed tomography revealed a 3.4 cm-sized soft tissue masses at periportal area. Endoscopic retrograde cholangiography showed nearly complete luminal obstruction of the distal common bile duct. Ultrasound-guided fine needle aspiration and biopsies showed epithelioid histiocytes and necrotic materials. Endoscopic nasobiliary drainage and successive antituberculous chemotherapy resolved obstructive jaundice and lymphadenopathy without surgical management. We report a case of obstructive jaundice due to tuberculous portal lymphadenitis.
카드뮴 중독과 연관된 성인형 Fanconi 증후군 1 예
박수현,한진석,구자룡,남은숙,여미애,곽성재,채동완,김근호,박규용,노정우,김형직,전로원,김현태,전은실 대한내과학회 2001 대한내과학회지 Vol.61 No.3
Adult Fanconi syndrome is a very rare disease characterized by renal glycosuria, generalized aminoaciduria, hypophosphatemia, hypouricemia and proximal renal tubular acidosis. It is divided into inherited and acquired forms. Proximal tubular transport defect in acquired Fanconi syndrome has been known to be resulted from multiple myeloma, dysproteinemias, heavy metal poisoning and chemical intoxications. A 50-year-old woman was admitted because of nausea for 2 weeks and body weight loss for 4 months. Leukocyte count, hemoglobin level and platelet count were 7,870/mm3, 11.7 g/dL 404,000/mm3 each. The urinalysis showed pH of 7.0, 3 positive for glucose and 3 positive for protein. The serum calcium, phosphate, uric acid and potassium were low to 8.9 mg/dL, 1.0 mg/dL, and 1.7 mEq/L. Serum creatinine level was 1.3mg/dL. The arterial blood gas analysis showed that the pH was 7.292 and bicarbonate was 14.7 mmol/L. Determination of amino acids in 24 hour urine specimen revealed the generalized aminoaciduria. Renal biopsy showed degeneration and necrosis of proximal tubules with normal glomeruli. Some tubular epithelial cells had enlarged nuclei and prominant nucleoli with vacuolated large mitochondrias. Cadmium concentrations of blood and urine were definitely higher than normal. The concentration of β2-microglobulin in urine was also high. Bicarbonate loading tests showed increased fractional excretions of bicarbonate in urine (6.129% at blood pH 7.248 and plasma HCO3 18.8 mEq/L, 13.7% at blood pH 7.315 and plasma HCO3 21.8 mEq/L). 24 hour urine protein electrophoresis showed no monoclonal gammopathy. This case of adult Fanconi syndrome was regarded to be related with cadmium intoxication. But no case of adult Fanconi syndrome related with cadmium toxicity has been reported yet in Korea. So authors report this case with brief review of literatures. (Korean J Med 61:276-280, 2001)
박수현,이준상,김형건,여미애,김지수,이중서,오흥영,곽성재 대한간학회 2000 Clinical and Molecular Hepatology(대한간학회지) Vol.6 No.2
Fluoxetine (Prozac ) is a antidepressant that inhibits the reuptake of serotonin in central nervous system, and has lesser adverse effects than the tricyclic antidepressants. The adverse effects of this drug are various, and the most common side effects are headache and nausea. The hepatic injury caused by fluoxetine is reported but very rare and not well known. Literature review has shown only 3 cases of hepatotoxicity from fluoxetine. We regard our case as the first of the hepatotoxicity from fluoxetine in Korea. The patient that we experienced showed normal aspartate aminotransferase (AST) and alanine aminotransferase (ALT) values before fluoxetine administration. 15 days after she took fluoxetine, AST and ALT values were increased and gradually increased as she took fluoxetine daily. We studied about viral hepatitis, metabolic liver disease, and autoimmune liver disease, but the cause of hepatic injury was not established. After the patient stopped to take fluoxetine, AST and ALT values decreased. A liver biopsy showed a moderate infiltration within the portal tracts with lymphocytes and ballooning degeneration of hepatocytes. We concluded fluoxetine-induced acute toxic hepatitis had occured. We must keep in mind that fluoxetine may cause hepatitis without cholestasis and suggest taking liver function tests regularly.(Korean J Hepatol 2000;6:236-240)