부분적인 Albright 의 선천성 골이영양증을 동반한 위부갑상선기능 저하증 1 예

고병구(Byoung Goo Ko),홍석구(Seok Gu Hong),진성호(Sung Ho Jin),박동철(Dong Chul Park),조준탁(Joon Tack Cho),이진관(Jin Kwan Lee) 대한내과학회 1986 대한내과학회지 Vol.31 No.1

N/A Pseudohypoparathyroidism is a genetic disorder characterized by target cell resistance to the effects of parathyroid hormone, In general the patients have hypocalcemia, hyperphosphosphathemia, elevated serum PTH level and a characteristic appearance termed Albright's hereditory osteodystrophy(AHO), The disorder is classified to type I and type g. Type I PsHP is subclassified to type la and type lb. Type Ia PsHP shows deficient G unit activity in target cell membrane and associated with other endocrine abnormalities and AHO in common. Type Ib PsHP shows normal G unit activity but deficient urinary cyclic AMP responce. Type Ⅱ PsHP shows normal c-AMP response to PTH, but also shows target cell resistance to PTH. We experienced a case of pseudohypoparathyroidism in 18 year old girl who had had frequent carpopedal spasm and generalized seizure for about 4 years. She had very low serum calcium level(3.8 mg/dL) and high immunoreactive PTH level(720 pg/ml), Even though every feature of AHO was not fulfilled, she had round face, short neck and obese stature. But she didn't have brachydactyly and subcutaneous calcification. She had no other endacrine abnormality but showed borderline mental retardation in IQ test. This case was of particular interest in that she showed incomplete presentation of AHO with pseudohypoparathyroidism.

선수 발굴을 위한 스포츠적성 진단모형 구안

고병구 ( Byoung Goo Ko ),구해모 ( Hai Mo Gu ),박동호 ( Dong Ho Park ),백진호 ( Jin Ho Back ),윤성원 ( Seong Won Yun ),이명천 ( Myung Chun Lee ),이종각 ( Jong Gak Lee ),장덕선 ( Duk Sun Chang ),신승윤 ( Seung Yun Shin ) 한국스포츠정책과학원(구 한국스포츠개발원) 2003 체육과학연구 Vol.14 No.1

본 연구에서는 선수 발굴을 위한 스포츠 적성 진단 모형을 구안하기 위하여 스포츠 영재 선발 모형의 일반적인 개발 절차를 고찰하였으며 이를 통해 스포츠 적성 진단 프로그램의 개발을 위한 이론적 요인 모형과 통계적 평가 모형으로 구성되는 기초스포츠적성진단모형과 전문스포츠적성진단모형을 구안하였다. 기초스포츠적성진단모형은 일반적인 스포츠 수행 능력의 진단 및 최적 스포츠 유형의 확인이라는 기능을 갖는 모형으로서 진단요인은 대부분의 스포츠 수행에 공통적으로 필요한 요인으로 선행연구 및 외국의 선발 항목에 대한 귀납적 범주분석, 그리고 전문가 협의를 거쳐 신장, 체중, 신체조성, 상지근력 및 근지구력, 상지순발력, 몸통근력 및 근지구력, 하지근력 및 근지구력, 하지순발력, 유산소능력, 스피드, 민첩성, 유연성으로 구성하였다. 전문스포츠적성진단모형은 기초스포츠적성진단에서 최우수로 평가된 청소년을 대상으로 종목 수행을 위한 보다 전문적인 능력을 진단하기 위한 모형으로 선행연구 및 외국의 선발 항목에 대한 고찰과 전문가의 협의에 의해 체격, 체력, 생리적 요구 요인은 종목별로 각각 구성하고, 의료검사, 성숙도검사, 심리 및 사회적 요인에 대한 검사는 전 종목 공통으로 구성하였다. 스포츠적성진단을 위한 평가모형의 통계적 절차는 T점수를 이용한 표준거리분석을 사용하였다. The purpose of this study was to construct sports talent identification models. For this purpose, the process for developing general talent identification models was reviewed and basic and specific sports talent identification models that are constructed with theoretical factor model and statistical evaluation model were designed. The basic sports talent identification model has a function for diagnosis of general sports performance ability and identification of optimal sports event. This theoretical factor model is constructed with common factors like as height, weight, body composition, arm strength, arm power, body strength, leg strength, leg power, aerobic ability, speed, agility, and flexibility that need to perform the most sports through inductive classification method on references to be connected with items to select athletes and expert seminars The specific sports talent identification model has the function for diagnosis of event specific ability for young people who have the best general sports ability. These theoretical factor models are constructed with specific factors like as physique, fitness, physiological characteristics that need to perform each sports event and also included with medical tests, a maturity test, psychological and sociological tests in common through inductive classification method on references to be connected with items to select athletes and expert seminars. And the evaluation model for sports talent identification was constructed by applying standard distance analysis using T-scores.

단시간 및 장기간의 세라젬 처치가 우수선수의 중추 피로 및 대사 변인에 미치는 영향

이종각 ( Jong Gak Lee ),고병구 ( Byoung Gu Ko ),김영수 ( Young Soo Kim ),박동호 ( Dong Ho Park ),정동식 ( Dong Sik Chung ),방대두 ( Dae Doo Bang ),방상식 ( Sang Sik Bang ),전만배 ( Man Bae Chun ) 한국스포츠정책과학원(구 한국스포츠개발원) 2003 체육과학연구 Vol.14 No.3

본 연구는 고강도 장시간의 훈련을 계속하는 레슬링과 유도 우수 선수들을 대상으로 카이로프랙틱, 스포츠 마사지와 원적외선 요법 등을 병용한 장비의 단시간(일회성) 및 장기간 (20주)의 적용이 선수의 피로회복에 영향을 미치는 중추피로 변인들(5-HT, dopamine, FFA, Flicker)과 동시에 부가적인 변인들(Na+, K+, Ca++, Pi, GH, IGF-I, Dpd, osteocalcin)의 변화를 관찰함으로써 장비이용에 대한 유용성을 검토하는데 있었다. 세라젬의 단시간과 장기간의 처치효과를 알아보기 위해, 26명의 피험자들은 무작위로 세라젬 처치집단(n=13)과 통제집단(n=13)으로 할당되었다. 장기간의 처치는 시선 및 10주, 20주 처치 후에 중추피로 변인들이 관찰되었으며, 단시간의 처치는 2시간 동안의 탈진 운동직후와 일회성의 세라젬 처치(40분간)후에 중추피로 변인들과 부가적인 변인들이 관찰되었다. 이원혼합분산분석과 공분산분석 등을 이용하여 세라젬 처치의 효과를 살펴본 결과 다음과 같은 결론을 얻었다. 1. 중추신경 피로변인들에 대한 세라젬 처치에 따른 장기간 반응으로는 Flicker test에서 비록 상호작용효과에서 유의한 차이는 없었으나 처치집단에서만 20주 처치 후에 유의하게 낮게 나타났다(p<.05). 2. 단시간 반응에서도 역시 Flicker 테스트에서 상호작용의 효과는 없었으나 단지 처치집단에서만 시기간 유의한 차이(p<.05)가 나타났다. 3. dopamin의 경우는 비록 통계적으로 유의한 차이는 없었으나(p<.05) 그 경험에 있어서 고강도 운동 직후 처치집단에 비해 상대적으로 통제집단에서 높은 경향이 나타난 반면 세라젬 처치 후 오히려 처치집단에서는 일정하게 그 농도가 유지되었으나 통제집단에서는 유의하게 낮아지는 현상이 나타났다. 4. 세라젬 처치에 따른 부가적인 변인들의 반응에서는 세라젬 처치를 받고 있는 처치집단의 경우 비록 40분간의 처치 후 GH의 농도가 비처치 집단과 거의 비슷한 수준까지 감소하였으나 고강도 탈진운동 직후에서 통제집단보다 2배 이상 높은 GH 농도(p<.05)가 관찰되었다. 이상의 결과와 선행 연구의 결과들을 종합하여 볼 때 세라젬 의료기의 이용을 통해 단시간 또는 장기간의 중추 신경피로를 부분적으로 감소 혹은 지연 할 수 있다고 사료되며, 특히 고강도 집중 훈련시에 활용한다면 피로 누적에 따른 오버트레이닝을 예방하는데 도움을 줄 수 있을 것으로 사료된다. To investigate the effect of short-term and long-term`s CGM-M treatment including far infrared, chiropractic and sports massage on changes of central fatigue variables (5-HT, dopamin, FFA, Flicker) affecting elite athlete`s fatigue recovery and additional variables(Na+, K+, Ca ++, Pi, GH, IGF-I, Dpe, osteocalcin) as well as to verify the availability of elite athlete`s equipment use. To compare concentrations of 5-HT, dopamin, FFA and Flicker test over time (baseline, 10-week, 20-week) for verifying the long-term effect of central fatigue, 26 top athletes of wrestling (n=13) and judo (n=13) were randomly assigned into treatment group (T; CGM-M treatment, n=13) and control group (C; n=13). In addition, central fatigue and additional variables were observed over time (immediately after high intensity all-out exercise for 2hr, P-AO and immediately after acute CGM-Mtreatment for 40min, P-T) for verifying the short-term treatment effect. To find out significant differences between groups (T & C), time conditions (baseline, 10-week & 20-week) and interactions (2 groups × 3 time conditions) for long-term as well as between groups (T & C), time conditions (P-AO & P-T) and interactions (2 groups × 2 time conditions), a mixed factorial design was condected, respectively and the results of this study were followed: l. Among the central fatigue variables, Flicker test`s score of only T group was significantly reduced (p<.05) at the 20-week time point of long-term although there was no significantly difference on the interaction effect. 2. Similarly, Flicker test`s score of only T group was also significantly reduced (p<.05) at the P-T time point of short-term although there was no significantly difference on the interaction effect. 3. Although there was no significant difference on the concentration of dopamine after high intensity exhaustive exercise, favorable tendency in the T group compared to the C group was observed over time. 4. There was significant difference observed in treatment group on GH (p<.05) after high intensity exhaustive exercise although increased GH concentration immediately after the exercise was reduced into the similar level of C group at P-T time point. Based on the results and previous researches, central fatigue might be partly reduced by using CGM-M treatment of short-term and long-term. Consequently, we assumed that using CGM-M especially during high intensity training of short-term may prevent the overtraining from the accumulation of fatigue.

결핵성 뇌막염에 합병된 중추성 뇨붕증 1 예

진성호,박동철,이진관,고병구,홍석구,조준탁 대한내과학회 1986 대한내과학회지 Vol.31 No.6

Central diabetes insipidus is a polyuric disorder that results from a lack of sufficient ADH to effect appropriate concentration of the urine for water conservation. It is divided into primary and secondary diabetes insipidus. The majority of secondary diabetes insipidus is caused by operation, neoplastic lesions of the pituitary and hypothalamus and head trauma. Secondary diabetes insipidus complicated with tuberculous meningitis is extremely rare. There have been several reports on diabetes insipidus but no reports on the disorder associated with tuberculous meningitis in Korea. We reported a patient of 38 year old male who developed diabetes insipidus during treatment of tuberculous meningitis and active pulmonary tuberculosis. Tuberculous meningitis was documented by clinical features, laboratory findings and therapeutic response, even though AFB smear of the cerebrospinal fluid was negative in the patient. Water deprivation and pitressin injection test revealed complete type of diabetes insipidus. We have followed this patient's status of diabetes insipidus up for one half year and he has been on 5 units of pitressin tannate in oil every 3 to 4 days. We think his status of diabetes insipidus in permanent.

원발성 갑상선 방선균증 1 예

진성호,박동철,이진관,고병구,홍석구,조준탁 대한내과학회 1986 대한내과학회지 Vol.31 No.6

Bacterial thyroiditis is a very uncommon disease caused most often by gram positive cocci such as Staphylococcus aureus, Streptococus pyogenes and Streptococcus pneumoniae. Primary actinomycosis of the thyroid is extremely rare. Since the first report in 1894, twelve patients have been described in Western literature. Bacause of infrequent occurrence and atypical presentation the clinical diagnosis of actinomycosis is very difficult, particulary in the thyroid gland. We experienced a case of actinomycosis of the thyroid in 48 year old farmer who had slowly growing hard mass in right anterior aspect of neck. On provisional diagnosis of thyroid carcinoma subtotal thyroidectomy and right anterior neck dissection was done. Histopathology showed acute and chronic inflammation with necrosis, abscess formation and 'sulfur granules' in right lobe of thyroid which were thought to be characteristic features of actinomycosis of the thyroid.