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Fibrinolysis of Fermented Kimchi
정영기,양웅석,강정욱,공인수,김정옥,Jeong, Yong-Kee,Yang, Woong-Suk,Kang, Jeong-Ok,Kong, In-Soo,Kim, Jeong-Ok Korean Society of Life Science 1995 생명과학회지 Vol.5 No.4
Fibrinolytic activity of fermented kimchi and ingredients used for the preparation were assayed by measuring the lysis area on plasminogen-rich fibrin plate. Fermented kimchi and picked fish sauces from changlan, prwan, and anchovy showed the activity, and the activity of pickled fish sauces were high in the order of pickled changlan, picked anchovy(pickled mulchi), and pickled prawn. However, the activity of kimchi may not be attributed to pickled fish sauce because kimchi containing fish sauce did not possess activities were determined from the samples heated for 30min at 100$\circ$C. There was no changes in activities before and after heat treatment indicating the agents may be components other than protein. Since major changes occur during kimchi fermentation were increased sour taste due to production of organic acids such as lactic, citric, oxalic, and succinic acids, the authentic organic acids present were examined for fibrinolytic activities. The results indicates that the major component posses the activity is lactic acid.
척추 결핵 환자의 수술적 치료 : 후방 기기 사용 여부에 따른 결과 비교
정영기,김석우,한현민,이응주,최수중,장준동 대한척추외과학회 1999 대한척추외과학회지 Vol.6 No.1
연구계획 : 척추 결핵으로 수술적 치료를 시행한 2 9명의 환자를 대상으로 고식적인 방법으로 전방 병소제거술후 골유합술만을 시행한 경우와 이에 부가하여 후방고정기기를 사용하여 수술을 한 경우로 나누어 결과를 비교하였다. 연구목적 : 척추 결핵의 수술적 치료를 위해 사용된 후방고정기기의 유용성 확인을 위하여 연구하였다. 대상 및 방법 : 29명의 척추 결핵 환자를 수술적 치료 방법에 따라 두 군으로 나누어 Ⅰ군은 전방 병소 제거후 골 유합술과 함께 후방 고정 기기술을 시행한 1 8례로 하고, Ⅱ군은 전방 병소 제거후 골 유합술만을 시행한 11례로 하 여, 각 군의 병변 부위 및 침범된 추체의 숫자에 따른 술후 및 최종 추시시 교정각의 변화, 합병증 등을 방사선 사 진과 병록으로 비교 분석하였다. 결과 : 흉추부와 흉요추부에서는 후방고정기기를 사용한 I군이 최종 추시시까지 교정각 소실이 상대적으로 적었으며, 침범된 추체의 증가에 따른 교정각 소실도 상대적으로 적었다. 하요추부에서는 양 군간의 술후 교정각 소실에 별다른 차이가 없었으며, 침범된 추체의 숫자의 증가에 따른 교정각 소실은 오히려 기기를 사용하지 않은 II군이 더 적었다. 결론 : 척추 결핵의 수술적 치료에서 고정 기기를 사용할 경우 병변이 흉추부와 흉요추부에 국한되고 2개이상의 추체를 침범할 경우에 후방고정기기를 이용하여 치료하는 것이 바람직할 것으로 사료된다. Study design : Twenty-nine patients with spinal tuberculousis were evaluated according to the surgical treatment methods using posterior spinal instrumentation and conventional anterior excision and interbody fusion methods without posterior spinal instrumentation. Objective : To confirm the effectiveness of the surgical treatment methods using posterior spinal instrumentation (combined with anterior radical excision and anterior interbody fusion ) in tuberculous spondylitis. Summary of Background data : Relatively good results(maintaining corrected kyphotic angle , short fusion time, rapid rehabilitation etc.)were obtained in posterior spinal instrumetnation group, especially at thoracic and thoracolumbar spine, but no specific benefits of posterior instrumentation at low lumbar spine during follow-up period. Methods: Twenty-nine patients with tuberculous spondylitis were divided into two groups depending on their use of posterior spinal instrument in surgical treatment methods ; one group consisted of 18 cases which were treated by anterior radical excision of involved body and anterior interbody fusion with posterior spinal instrumentation(Group I), and the other groups consisted of 11 cases which were treated by anterior radical excision of involved body and anterior interbody fusion(Group II). Change of corrected kyphotic angle according to the level of lesion, number of involved body and complications were measured using pre-, post-operative, and follow-up radiographs and chart review. Results : Comparing the two groups, relatively short fusion time, less kyphotic angle loss, and low complication rates were obtained in posterior spinal instrumentation group(Group I) during the follow up period, especilally, at thoracic and thoracolumbar spine. However, there were no significant postoperative and follow-up results in both groups at low lumbar spine. Conclusions : Tuberculous spondylitis can be treated, and correction can be maintained with anterior radical excision of involved body and anterior interbody fusion with posterior spinal instrumentation during follow up period.