o-Chlorobenzylidenemalononitrile의 가수분해 및 분석에 관한 연구

박성우,김남이,김동환,홍성욱,성낙도,김일광,오인교,Park, Sung-Woo,Kim, Nam-Yee,Kim, Dong-Hwan,Hong, Sung-Work,Sung, Nack-Do,Kim, Il-Kwang,Oh, In-Kio 한국분석과학회 1992 분석과학 Vol.5 No.4

o-Chlorobenzylidenemalononitrile(CS), chloroacetophenone 및 bromophenylacetonitrile의 이성질체와 같은 최루 자극성 물질들의 가수분해, 산화, 환원, 열분해 및 대사에 의한 화합물의 분석은 법과학적 측면에서 주요한 의미가 있다. 본 실험에서는 10% MeOH-$H_2O$ 및 10% dioxane-$H_2O$ 용액에서 pH 1.0~11.0과 온도 변화에 따른 CS의 가수분해 조건을 검토하고 가수분해 생성물이 o-chlorobenzaldehyde와 malononitrile임을 분광학적 방법 및 전기화학적 방법에 의해 확인하였다. The analysis, hydrolysis mechanism, oxidation, reduction, thermal decomposition and metabolism of irritant materials such as chloroacetophenone isomers, bromophenylacetonitrile isomers, o-chlorobenzylidenemalononitrile(CS), and ethylisothiocyanate, etc. are interested in forensic science. We had studied hydrolysis of CS in 10% MeOH-$H_2O$ and 10% dioxane-$H_2O$ at pH 1.0~11.0 and various temperatures. As a result, we identified o-chlorobenzaldehyde and malononitrile that were formed by hydrolysis of CS by using gas chromatography/mass spectrometry, UV/Vis spectrometry, and polarographic method.

정자형성 과정에서 Vascular Endothelial Growth Factor 및 Endothelin-1 발현의 면역조직화학적 연구

박성우,박현준,박남철,Park, Sung-Woo,Park, Hyun-Jun,Park, Nam-Cheol 대한생식의학회 2004 Clinical and Experimental Reproductive Medicine Vol.31 No.4

Objective: The effects on spermatogenesis by expression of vascular endothelial growth factor (VEGF) and endothelin-1 (ET-1) were investigated. Materials and Methods: Testicular specimens were obtained from 40 infertile males due to primary testicular failure and from 10 fertile males with other urologic problems. The specimens of infertile males were devided into 4 groups according to histologic findings; Sertoli cell only syndrome (A), maturation arrest (B), hypospermatogenesis (C) and sloughing and disorganization (D). VEGF and ET-1 expression were detected with immunohistochemical stain. Results: VEGF expression on Leydig cell was detected in all cases. But, VEGF expression rates on germ cell were significantly higher in infertile group B, C, D compared to that of the control group (p<0.05). ET-1 expression rates on Leydig cell was significantly lower in all infertile group compared to that of the control group (p<0.05). But, ET-1 expression rates on Sertoli cell was significantly higher in all infertile group compared to that of the control group (p>0.05). In germ cell of infertile group, LH, FSH and prolactin were significantly decreased, and estradiol is increased in positive stain group on ET-1 immunohistochemical stain (p<0.05). VEGF and ET-1 expression were not correlated mean seminiferous tubule diameter (p>0.05). Conclusions: Abnormal spermatogenesis would be reflected in VEGF expression in germ cell.

폭약류의 법과학적 분석 (II)

박성우,김동환,유재훈,Park, Sung-Woo,Kim, Dong-Hwan,You, Jae-Hoon 한국분석과학회 1998 분석과학 Vol.11 No.3

Trimethylgermanium 화합물과 Chloral의 반응

박성우,이일규,Sung Woo Park,Kyu Il Lee 대한화학회 1984 대한화학회지 Vol.28 No.1

글루칸 투여에 의한 한국산 메기(Silurus asotus)의 Edwardsiella ictaluri와 Aeromonas hydrophila감염증에 대한 저항성의 증가

박성우,김영길,Park, Sung-Woo,Kim, Young-Gill 한국어병학회 1996 한국어병학회지 Vol.9 No.1

$\beta$-glucan의 투여가 세균감염증에 대한 저항성에 미치는 영향을 알아보기 위하여 복강주사 또는 침지에 의해 한국산 메기(Silurus asotus)에 투여하였다. 투여 농도는 어체중 100 g 당 200, 500, $1000{\mu}g$을 1회 또는 3일 간격으로 2회 복강주사하거나, $100{\mu}g$/ml의 $\beta$-glucan 부유액에 30분 또는 1시간 침지시켰다. $\beta$-glucan 투여 3일후에 Edwardsiella ictaluri와 Aeromonas hydrophila의 생균액($2{\times}106$ CFU/0.1 ml)을 복강주사한 다음 10일간 사육하면서 생존율을 조사하였다. 복강주사와 침지에 의한 투여결과 복장투여만이 생잔율을 높일 수 있었으며, 투여 농도에 있어 어체중 100 g당 $200\sim1000{\mu}g$의 범위에 있어서는 농도간에 차이가 없었다. 또한 투여회수는 1회 투여보다는 3일간격으로 2회 투여가 효과적이었으며, E. ictaluri보다는 A. hydrophila에 대한 저항성이 높은 것으로 나타나, 한국산 메기에 $\beta$-glucan을 복강투여함으로서 세균감염증의 초기단계에 있어 생잔율을 높일 수 있었다. The effect of $\beta$-glucan administration on the resistance of Korean catfish(Silurus asotus) to experimental Edwardsiella ictaluri and Aeromonas hydrophila infection was evaluated. Fish were either intraperitoneally received $\beta$-glucan($200\sim1000{\mu}g$/100g body weight) dissolved in physiological saline once or twice at an intervals of 3 days, or placed in $\beta$-glucan bath($100{\mu}g/m\ell$) prepared with filtered tap water for 30 or 60 min. Bacterial challenge was performed by intraperitoneal injection of 0.1 ml of bacteria suspension($2{\times}10^7 CFU/m\ell$) 3 days after $\beta$-glucan administration. The $\beta$-glucan injected fish showed an significantly enhanced resistance against experimental infections. The resistance was much higher in the twice-injected fish than in the once-injected fish. But glucan bath did not affect survival rate after the challenge. The protective effect in the $\beta$-glucan injected fish was higher to A. hydrophila than to E. ictaluri. These results indicate that $\beta$-glucan injection can increase the resistance of Korean catfish against experimental E. ictaluri and A. hydrophila infection and that twice injection of $\beta$-glucan at an 3 day-intervals is more effective to the resistance.

Trimethylgermanium화합물과 ${\beta}$-propiolactone의 반응

박성우,서배석,김갑주,이일규,Sung-Woo Park,Bae-Seok Seo,Ghap-Ju Ghim,Il-Kyu Lee 대한화학회 1985 대한화학회지 Vol.29 No.5

가상스튜디오 구현을 위한 실시간 카메라 추적

박성우,서용덕,홍기상,Park, Seong-Woo,Seo, Yong-Duek,Hong, Ki-Sang 대한전자공학회 1999 電子工學會論文誌, S Vol.s36 No.7

가상스튜디오의 구현을 위해서 카메라의 움직임을 실시간으로 알아내는 것이 필수적이다. 기존의 가상스튜디어 구현에 사용되는 기계적인 방법을 이용한 카메라의 움직임 추적하는 방법에서 나타나는 단점들을 해결하기 위해 본 논문에서는 카메라로부터 얻어진 영상을 이용해 컴퓨터비전 기술을 응용하여 실시간으로 카메라변수들을 알아내기 위한 전체적인 알고리듬을 제안하고 실제 구현을 위한 시스템의 구성 방법에 대해 다룬다. 본 연구에서는 실시간 카메라변수 추출을 위해 영상에서 특징점을 자동으로 추출하고 인식하기 위한 방법과, 카메라 캘리브레이션 과정에서 렌즈의 왜곡특성 계산에 따른 계산량 문제를 해결하기 위한 방법을 제안한다. In this paper, we present an overall algorithm for real-time camera parameter extraction which is one of key elements in implementing virtual studio. The prevailing mechanical methode for tracking cameras have several disadvantage such as the price, calibration with the camera and operability. To overcome these disadvantages we calculate camera parameters directly from the input image using computer-vision technique. When using zoom lenses, it requires real time calculation of lens distortion. But in Tsai algorithm, adopted for camera calibration, it can be calculated through nonlinear optimization in triple parameter space, which usually takes long computation time. We proposed a new method, separating lens distortion parameter from the other two parameters, so that it is reduced to nonlinear optimization in one parameter space, which can be computed fast enough for real time application.

$\beta$-glucan을 접종한 한국산 메기(Silurus asotus)의 호중구와 리소자임 활성 증강

박성우,김영길,최동림,Park, Sung-Woo,Kim, Young-Gill,Choi, Dong-Lim 한국어병학회 1996 한국어병학회지 Vol.9 No.1

한국산 메기(Silurus asotus)에 $\beta$-glucan을 복강내에 접종한 후, 경시적으로 말초혈액중의 호중구의 수와 PAS반응의 변화, 호중구의 탐식능 및 혈청중의 리소자임의 활성변화를 지표로 비특이적방어능력의 증강유무를 조사하였다. 글루칸의 투여후 말초혈액중의 호중구수를 증가시켰으며 투여회수에 따라 2회 접종한 경우 호중구의 증가가 지속되는 기간이 1회 접종어보다 길게 나타났다. 그러나 호중구의 PAS반응에는 변화가 없었다. 또 탐식율도 현저하게 증가하였지만 탐식지수는 변화가 없었다. 리소자임의 활성은 2회 접종시만이 현저히 증가하였으나 1회 접종시에는 활성의 증가가 없었다. 그러므로 $\beta$-glucan의 투여는 말초혈액중의 호중구수와 탐식능의 증가 및 리소자임 활성의 증가등 비특이적방어인자의 활성을 증가시켜 어체를 방어하는 능력을 증강시키는 것임을 알 수 있다. To examine the effectiveness of $\beta$-glucan in non-specific defence mecanisms of Korean catfish(Silurus asotus), the activities of peripheral neutrophils and serum lysozyme were evaluated after once or twice $\beta$-glucan injections. The number of peripheral neutrophils increased after the injection. The increased number in neutrophils in twice $\beta$-glucan injections maintained longer than in single glucan injecton. But the neutrophils did not showed any remarkable changes in PAS-positive reaction. Peripheral neutrophils from fish injected glucan had enhanced phagocytic activities but there was no significant difference in phagocytic index for the glucan and control groups. An elevation of lysozome activity was also observed in the fish received twice glucan but neither single glucan or physiological saline injection could not evoked an increase of lysozyme activity. These results suggest that $\beta$-glucan can enhance the resistance of Korean catfish against to bacteria infection through the activation of peripheral neutrophils and lysozyme.

Triethylgermyldiphenylphosphine과 Phenylisocyanate의 반응

박성우,이일규,Sung Woo Park,Il Kyu Lee 대한화학회 1983 대한화학회지 Vol.27 No.1

Triethylgermyldiphenylphosphine과 phenylisocyanate를 1:10 mole 비로 ampoule 속에서 혼합하여 여러 온도에서 반응시켰다. 그 결과 $0^{\circ}C$에서는 phenylisocyanate의 고리화 2합체인 N, N-diphenyluretidine-2,4-dione만이, $20^{\circ}C$에서는 phenylisocyanate의 고리화 3합체인 triphenylisocyanurate가 함께 생성되었으며, $50^{\circ}C$에서는 위의 생성물 이외에 diphenylcarbodiimide가 생성되었다. 또한 $100^{\circ}C$이상에서는 2합체는 생성되지 않고, diphenylcarbodiimide와 1,3,5-triphenyl-2,4,6-tris(phenylimino) hexahydro-1,3,5-triazine이 주로 생성되었다. 그리고 Triethylgermyldiphenylphosphine은 상기 고리 화합물들의 생성에 촉매로 작용하였다. Triethylgermyldiphenylphosphine was reacted with phenylisocyanate at various temperatures for three days in sealed ampoules. At $0^{\circ}C$, only N, N-diphenyluretidine-2,4-dione, a cyclic dimer of phenylisocyanate (35%), was formed. But at $20^{\circ}C$, phenylisocyanutrate, a cyclic trimer of phenylisocyanate (30%), was formed along with the dimer. At $50^{\circ}C$, diphenylcarbodiimide (55%) was given together with the compounds described above. At the higher reaction temperatures than $100^{\circ}C$, instead of the dimer and trimer of phenylisocyanate, 1,3,5-triphenyl-2,4,6-tris(phenylimino) hexahydro-1,3,5-triazine, a cyclic trimer of diphenylcarbodiimide (30%) and diphenylcarbodiimide (70%) were mainly produced. Triethylgermyldiphenylphosphine appears to act as a catalyst for the formation of the above cyclic compounds.

경피적 신동맥 혈관 성형술로 치료한 신혈관 고혈압증 1례

박성우,정수호,전용선,전용훈,홍영진,이지은,Park, Sung-Woo,Jeong, Su-Ho,Jeong, Young-Sun,Jun, Yong-Hoon,Hong, Young-Jin,Lee, Ji-Eun 대한소아신장학회 2008 Childhood kidney diseases Vol.12 No.1

신성 고혈압은 소아기 이차성 고혈압의 흔한 원인이며, 그 중 신동맥 협착에 의한 신혈관성 고혈압은 치료 가능한 고혈압의 가장 흔한 원인이다. 신혈관성 고혈압 치료로 최근 경피적 신동맥 혈관 성형술은 비침습적인 방법으로 각광 받고 있다. 저자들은 작은 직경을 가진 신동맥 분지 혈관 협착에 의한 신혈관성 고혈압 소아에서 관상동맥용으로 쓰이는 풍선 카테터를 이용하여 경피적 신동맥혈관 성형술을 성공적으로 시행한 경험을 하였으므로 보고하는 바이다. Renovascular hypertension results from a lesion that impairs blood flow to a part of or all, of one or both kidneys. Renal artery stenosis is the major cause of renovascular hypertension and the most common cause of treatable secondary hypertension. Recently, percutaneous transluminal renal angioplasty(PTRA) with or without stent placement, has become the preferred choice for correcting symptomatic renal artery stenosis since it is less invasive than surgical reconstruction. PTRA with balloons designed for the dilatation for the dilatation of the coronary artery can be tried in small sized renal artery stenosis. We report a case of renovascular hypertension in a 13-year-old male who had small sized renal artery stenosis. Hypertension was controlled by PTRA with balloon dilatation.