http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
( Yong Tark Jeon ),( Chang Suk Suh ),( Yong Beom Kim ) 대한산부인과학회 2009 Journal of Womens Medicine Vol.2 No.2
Objective: The aim of this study was to investigate the appropriate management of patients with negative cytology, but positive high risk HPV testing. Methods: Medical records were reviewed for patients who had cervical cancer screening by both Pap smear and HPV DNA testing between January 2003 and December 2006. Among 3,158 patients who had both Pap smears and HPV DNA tests, 516 patients had negative cytology with positive high risk HPV. After exclusion of 237 cases in which follow-up data were not available, the remaining 279 cases were reviewed. Results: After a mean follow-up period of 12.3±8.6 months, 250 cases (89.6%) had consecutive normal cytologies by biannual Pap smears and 29 cases (10.4%) had abnormal cytologies. The results of colposcopy-directed punch biopsy for these abnormal cytologies were 18 cases of chronic cervicitis (6.5%), 2 case of flat condyloma (0.7%), 5 case of CIN I (1.8%), 3 cases of CIN III (1.1%), and 1 case of verrucous hemangioma (0.4%). Conclusion: Our follow-up cytology and biopsy results suggest that frequent exams at less than 12 month intervals is unnecessary for women with positive for high risk HPV and negative cytology.
세부 전공에 따른 자궁경부상피내종양의 처치로써 환상투열 절제술에 대한 태도 분석
전용탁 ( Yong Tark Jeon ),민경준 ( Kyung Joon Min ),지병철 ( Byung Chul Jee ),김용범 ( Yong Beom Kim ),박교훈 ( Kyo Hoon Park ),서창석 ( Chang Suk Suh ) 대한산부인과학회 2005 Obstetrics & Gynecology Science Vol.48 No.3
목적: 부인종양 전임의 과정을 거친 산부인과 전문의와 그렇지 않은 경우에 있어서 자궁경부상피내종양의 처치로써 환상투열 절제술 (LLETZ)에 대한 태도에 차이가 있는지를 알아보고자 하였다. 연구 방법: 2003년 6월부터 2004년 9월까지 분당서울대학교병원 산부인과에서 LLETZ를 시행한 81명의 환자를 대상으로 하였다. LLETZ와 질확대경하 조직생검 소견을 의무기록을 통해 조사하였고, 부인종양학 전임의 과정을 거친 의사에게 시술을 받은 군 (GO Objective: The aim of this study is to compare the clinician`s attitude to the large loop excision of transformation zone (LLETZ) according to the subspecialty; gynecologic oncology or not. Methods: Eighty-one patients who had LLETZ at Seoul National Univ
긴장성 요실금의 수술적 치료에서 Tension-free vaginal tape (TVT)과 Transobturator tape (TOT)의 효과에 대한 예비 보고
전용탁 ( Yong Tark Jeon ),황태기 ( Tae Gi Hwang ),민경준 ( Kyung Joon Min ),지병철 ( Byung Chul Jee ),김용범 ( Yong Beom Kim ),박교훈 ( Kyo Hoon Park ),서창석 ( Chang Suk Suh ) 대한산부인과학회 2005 Obstetrics & Gynecology Science Vol.48 No.5
자기공명영상에 의한 자궁내막암의 자궁근층 , 자궁경부 침윤 판별과 수술적 병기와의 비교
전용탁(Yong Tark Jeon),황규리(Kyu Ri Hwang),김재원(Jae Weon Kim),박노현(Noh Hyun Park),송용상(Yong Sang Song),강순범(Soon Beom Kang),이효표(Hyo Pyo Lee) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.9
N/A Objective : The aim of this study was accuracy evaluation of MRI in prediction of myometrial, cervical invasion in endometrial carcinoma by comparing with histopathologic findings and to find causes of inaccurate MRI readings. Method : Fifty patients with endometrial carcinoma who were evaluated with MRI imaging prior to surgery were reviewed. And then, we compared MRI findings and histopathologic findings in view of myometrial, cervical invasion. Results : Overall accuracy of MRI in prediction of myometrial invasion was 48%. Sensitivity/specificity/ PPV/NPV in prediction of no myometrial invasion were 100%/42.9%/42.9%/100% respectively, in prediction of superficial myometrial invasion were 20.0%/86.7%/50.0%/61.9% respectively, in prediction of deep myometrial invasion were 33.3%/94.3%/71.4%/76.7%, respectively. Accuracy in prediction of cervical invasion was 84% and sensitivity/specificity/PPV/NPV were 50.0%/88.6%/37.5%/92.9% respectively. Among the probable causes of inaccurate MRI readings, polypoid tumor occupies large portion. Conclusion : MRI has some value in pre-operative evaluation of patients with endometrial carcinoma. We should cautiously accept the MRI readings when tumor shows polypoid growth.
Kim, Yong Beom,Song, Yong Sang,Jeon, Yong Tark,Park, Jong Sup,Um, Soo Jong,Kim, Jae Weon,Park, Noh Hyun,Kang, Soon Beom,Lee, Hyo Pyo National Hellenic Research Foundation 2005 ONCOLOGY REPORTS Vol.14 No.2
<P>In this study, we investigated the sequence variation and different transcriptional activities of the upstream regulatory region (URR) in HPV 16 E7 variants in cervical cancer tissue from Korean women. Using PCR-directed sequencing, the presence of sequence variations in URRs were analyzed and the sites of sequence variation were matched with the known transcriptional factor binding site (TFBS) in 26 HPV 16 E7 variants, 21 cases with A647G (KE7-1, high oncogenic potential) and 5 cases with T732C (KE7-2, low oncogenic potential). In addition, we determined the transcriptional activity of URR in a HPV 16 prototype, and in 4 cases of HPV 16 E7 variants, by using the functional chloramphenicol acetyl transferase (CAT) assay. The 26 HPV 16 E7 variants showed more than 11 sites of sequence variation in the URR. Ten sites of sequence variation were located in the known TFBS and the distribution of sequence variations in the URR showed clear differences between KE7-1 and KE7-2. The sequence variations T7781C and C7786T were matched with YY1 binding sites, G7193T and C7689A were matched with TEF1 binding sites, and C7394T and C7395T were matched with GRE binding sites. The other sequence variations, which were matched with the TFBS, were A7485C, G7489A, T7743G and G7842A. The URR activity of KE7-1 was significantly lower than that of the HPV 16 prototype, whilst KE7-2 was similar. Taken together with the results of the transcriptional activities of KE7-1 and KE7-2, our results suggest that the functional activity and sequence variations of HPV 16 URR may not be related to the oncogenic potential of HPV 16 E7 variants.</P>
김용범 ( Yong Beom Kim ),전용탁 ( Yong Tark Jeon ),서상수 ( Sang Soo Seo ),김재원 ( Jae Weon Kim ),박노현 ( Noh Hyun Park ),송용상 ( Yong Sang Song ),강순범 ( Soon Beom Kang ),이효표 ( Hyo Pyo Lee ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.4
목적 : 최근에 그 효용성이 확대되고 있는 DNA chip을 이용하여 우리나라 자궁경부암 환자에서 발견되는 고위험군 HPV 감염 빈도와 아형의 분포를 알아보고 동시에 자궁경부암의 각 조직병리학적 종류에 따라 발견되는 고위험군 HPV 아형의 빈도와 분포에 따른 차이의 여부를 알아보고자 하였다. 연구 방법 : 1998년 2월부터 2001년 2월까지 서울대학교병원 산부인과에서 자궁경부암 (FIGO stage Ⅰa1-Ⅱa)으로 자궁절제술 혹은 근치적 자궁절제술 Objective : To evaluate the prevalence and genotype of high risk HPV infection with oligonucleotide microarray based DNA chip in cervical cancer. Methods : The presence of HPV and its type were tested with oligonucleotide microarray based DNA chip in 84 s
전용탁 ( Yong Tark Jeon ),양혜진 ( Hye Jin Yang ),손영수 ( Young Soo Son ),지병철 ( Byung Chul Jee ),김용범 ( Yong Beom Kim ),박교훈 ( Kyo Hoon Park ),서창석 ( Chang Suk Suh ) 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.10
Vaginal and cervical agenesis is an uncommon Mullerian anomaly. Total hysterectomy and vaginoplasty remains the classical treatment of this malformation. We present a case of reconstruction of utero-neovaginal continuity in the patient with normal functio