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      • KCI등재

        Mineral trioxide aggregate와 그 대체재료

        조용범 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.3

        Since its introduction in 1993, Mineral Trioxide Aggregate (MTA) has been shown to be superior to others in sealing, biocompatibility, and many other aspects of clinical endodontics. MTA is primarily Portland cement with bismuth oxide as a radiopacitifier. Although some studies suggested that the reasonable-priced Portland cement could be used instead of MTA, but MTAs are different from Portland cement in its composition, especially in heavy metal contents. Therefore, clinicians should be meticulous adapting the Portland cement as a MTA substitute.

      • 근관내 여러 조건에서의 ROOT ZX 전자근관장 측정기의 정확성에 관한 연구

        조용범,홍한표,홍찬의 단국대학교 치의학연구소 1994 논문집 Vol.6 No.1

        The technique of electronic working length determination has gained considerable popularity among both endodontists and general dentist. Recently, the Root ZX(J.Morita Corp., Tokyo, Japan) has been developed with unique electronic features that are claimed to maintain the instrument's accuracy regardless of canal condition. The purpose of this study is to compare the accuracy of the Root ZX with estimates of actual canal length, in vitro model and in vivo under the various condition. 1. The experiment in vitro model 50 extracted, single-rooted and single-canaled, teeth with mature apices were selected. The extirpated teeth were placed in a saline-soaked Oasis, and measured with Root ZX according to manufacturer's instruction in the dried canal and saline-irrigated canal. The teeth were then removed from the model and the actual canal length was measured. The values of canal length in each conditions were used for evaluating the results. 2. In vivo study 15 teeth which destined for extraction were selected. Once access was gained, the canals were irrigated using 5.25% sodium hypochlorite and were not dried prior to insertion of the measurement file. Once the Root ZX indicated the C-D junction, self-curing resin was injected into the canal. The tooth was extracted and ground with a bur and Soflex disk. This was done until the terminus of the file and the root was revealed. The distance from the end of the file to the foramen(major diameter) was measure, and evaluated. The results were as follows: 1. In vitro study(A/B : difference between A and B) 1). The mean values of acutal length/dried canal length and actual length/saline irrigated canal length were 0.528㎜, and 0.525㎜ respectively. There is no significant difference between the means of acutal length/dried canal length and actual length/saline irrigated canal length. 2). Root ZX could locate the C-D junction at the point of 0.5㎜ inside of major foramen, in both dried canal and saline-irrigated canal. 2. In vivo study 1). Root ZX could locate the the C-D junction at the point of 0.5㎜ coronal to the major foramen in presence of 5.25% NaOCl. 2). Root Zx located a point that was perceived to be the apical constriction. The majority of file tip experimented were within the canal, not extended beyond the major foramen.

      • KCI등재
      • KCI등재
      • 人蔘 Total Saponin, Protopanaxadiol 및 Protopanaxatriol의 消炎作用에 關한 硏究

        조태순,이선미,정국현,이범구,이석용,박종대 성균관대학교 약학연구소 1999 成均藥硏論文集 Vol.11 No.-

        Abstract-In an attempt to elucidate the anti-inflammatory action of ginseng total saponin, protopanaxadiol and protopanaxatriol, the anti-inflammatory activity of three compounds was investigated under various acute and chronic inflammatory models. The blood vessel permeability was slightly inhibited by total saponin and protopanaxatriol treatments. Granuloma formation induced by 2% carrageenan was inhibited by total saponin and protopanaxatriol. The cotton-pellet granuloma formation was significantly inhibited by intraperitoneal injection of total saponin. Total saponin and protopanaxadiol inhibited leukocyte emigration and protein exudation in CMC-induced pouch but protopanaxatriol increased leukocyte emigration. The swelling of rat hind paw induced by 1% carrageenan was significantly inhibited by total saponin, protopanaxadiol and protopanaxatriol both single and 2 weeks treatments. Total saponin, protopanaxadiol and protopanaxatriol decreased the anti-inflammatory activity in adrenalectomized rat. Our results suggest that total saponin, protopanaxadiol and protopanaxatriol have potent anti-inflammatory activity, this may be mediated in part through stimulation of adrenal glands.

      • SCIESCOPUSKCI등재

        퇴행성 척추질환으로 오인된 척수 종양

        조용재,김승범,진동규,서의교,김상진 대한척추신경외과학회 2004 Neurospine Vol.1 No.1

        Objectives: Symptoms arising from spinal cord tumor are often insidious in onset and nonspecific in nature. To make the subtle initial signs and symptoms of these tumors more apparent to clinicians, we retrospectively analyzed the data of spinal cord tumor patients who were misdiagnosed as degenerative spine disease. Methods: We reviewed history, symptom, sign, radiological study, and pathologic diagnosis of 19 spinal cord tumor patients who had been operated as degenerative spine disease, especially duration and description of symptoms and sign before an accurate diagnosis was made. Results: Average duration of delay before an accurate diagnosis was made was 178.4 days(range: 23~303). Common symptom and signs on neurologic examination included aggravation of pain(8 cases; 47.1 %), and neurologic decline(9 cases; 52.9%) The misdiagnosis included a herniated lumbar disc(16 cases; 94.1%), lumbar stenosis(1 case; 5.9%). Inappropriate treatment for these misdiagnoses included 5 percutaneous lazer discectomies, 9 discectomies, 3 chemonucleolysis, 2 posterior lumbar interbody fusions with cages. Conclusion: When a patient has symptoms that appear to be out of the ordinary, surgeons should suspect other spinal disease including the spinal cord tumor.

      • 기본 항암 화학요법에 불응 하는 전이성 이행상피 세포암 환자에서 시행한 증량 M-VAC 항암 화학 요법 2례

        조용현,권병산,이지열,김세웅,이충범,윤문수 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.3

        1. 목적 전이성 방광 이행 상피 세포암의 경우에 시행될 수 있는 몇가지 전신적 항암 요법 중 M-VAC 병용 투여가 가장 인정받고 있는 항암 요법이긴 하나 일시적 반응 후 재발시 즉 M-VAC 병용투여에 불응하는 경우 증상 완화 요법(palliative therapy) 이외에 다른 치료 방법이 없었다. 저자들은 M-VAC 병용 요법에 불응하는 전이성 방광 이행상피 세포암 환자 2례에서 기존 M-VAC 항암 화학 요법보다 항암제 투여량을 증량한 M-VAC 항암 요법을 시행하였다. 2. 방법 기존 M-VAC 항암 화학요법용량(Methotrexate 30㎎/㎡, Vinblastine 3㎎/㎡, Adriamysin 30㎎/㎡, Cisplatin 70㎎/㎡)보다 항암제 용량을 증량하고(Methotrexate 30㎎/㎡, Vinblastine 4㎎/㎡, Adriamycin 60㎎/㎡, Cisplatin 100㎎/㎡) 이로 인한 골수 저하증을 예방하기 위하여 GM-CSF를 동시에 투여하였다. 3. 결과 증례 1 환자는 중량 항암 화학 요법 1개월 후 추적검사에서 전이된 임파절이 모두 소실된 완전 관해를 보였으며 증례 2 환자는 증량 항암 요법 후 14일째 폐혈증으로 사망하였다. 4. 결론 증량 M-VAC 항암 화학 요법은 아직 시행 기간 및 증례가 많지 않아 완전 관해 기간 및 적절한 항암요법 시행 횟수의 미확립, 항암제 치료 도중의 치사율의 감소등이 문제점으로 지적되고 있으나 기존 M-VAC 항암 요법에 불응하는 전이성 방광이행 상피 세포암 환자에서 우선 고려될 수 있는 치료법으로 사료된다. Background : M-VAC(methotrexate, vinblastine. doxorclbicin, cisplatin) chemotherapy is the most common and effective treatment modality for advanced transitional bladder tumor. However, there is no effective therapy in case of the patients nith bladder tumor refractory to M-VAC chemotherapy. Methods : Two male patients mith metastatic transitional bladder tumors refractory to conventional chemotherapy with methbtrexate, vinblastine, doxorubicim, and cispiatin (M-VAC) were treated with escalate3 dose of M-VAC plus recombinant human granulocyte-macrophage colony stimulating factor (rhGM-CSF). Formula of escalated M-VAC chemotherapy were 30mg/m^(2) of inethotrexate, 4mg/m^(2) of vinblastine. 60rmg/m^(2) of doxorubicm, and 10Omg/m^(2) of cisplatin, and 250mg/m^(2) rhGM-CSF per day administered subcutaneously (SC) for 10 consecutive days. Result : One of the treated patients mas responded with complete remission and the other one m-as dead by sepsis on post-escalated M-VAC chenctherapy 14 days. Coclusion : We believe escalated M-VAC chemotherapy may be one of the effective alternative treatment for patients with metastatic urothelial tumor refractory to conventional M-VAC chemotherapy.

      • KCI등재
      • 홍수퇴적토의 식재토양 재활용 연구

        조용현,조항문,현재혁,조재범,김갑수 忠南大學校 環境問題硏究所 1997 環境硏究 Vol.15 No.-

        In the study , the feasibility of deposit soil in river and stream bed as a substitute for conventional plant soil was investigated through the analysis of soil characteristics and germination growth rate for 75days. Proper mix between samples from different places was compared to optimize the germination and growth rate of plant in the ratio of 2 : 1 and 3 : 1 (sand : deposit). From the results, it could be concluded that the deposit mix 3 : 1 showed most favorable germination and growth conditions for pancy and the deposit containing enough amount of silt and clay components showed most favorable conditions for marigold. Consequently, the feasibility of deposits as a substitutional plant soil was evaluated to be high.

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