Sensing Performance of Efficient Cyclostationary Detector with Multiple Antennas in Multipath Fading and Lognormal Shadowing Environments

Zhu, Ying,Liu, Jia,Feng, Zhiyong,Zhang, Ping The Korea Institute of Information and Commucation 2014 Journal of communications and networks Vol.16 No.2

Spectrum sensing is a key technical challenge for cognitive radio (CR). It is well known that multicycle cyclostationarity (MC) detection is a powerful method for spectrum sensing. However, a conventional MC detector is difficult to implement because of its high computational complexity. This paper considers reducing computational complexity by simplifying the test statistic of a conventional MC detector. On the basis of this simplification process, an improved MC detector is proposed. Compared with the conventional detector, the proposed detector has low-computational complexity and high-accuracy sensing performance. Subsequently, the sensing performance is further investigated for the cases of Rayleigh, Nakagami-m, Rician, and Rayleigh fading and lognormal shadowing channels. Furthermore, square-law combining (SLC) is introduced to improve the detection capability in fading and shadowing environments. The corresponding closed-form expressions of average detection probability are derived for each case by the moment generation function (MGF) and contour integral approaches. Finally, illustrative and analytical results show the efficiency and reliability of the proposed detector and the improvement in sensing performance by SLC in multipath fading and lognormal shadowing environments.

Influence of non-Gaussian characteristics of wind load on fatigue damage of wind turbine

Ying Zhu,Miao Shuang 한국풍공학회 2020 Wind and Structures, An International Journal (WAS Vol.31 No.3

Based on translation models, both Gaussian and non-Gaussian wind fields are generated using spectral representation method for investigating the influence of non-Gaussian characteristics and directivity effect of wind load on fatigue damage of wind turbine. Using the blade aerodynamic model and multi-body dynamics, dynamic responses are calculated. Using linear damage accumulation theory and linear crack propagation theory, crack initiation life and crack propagation life are discussed with consideration of the joint probability density distribution of the wind direction and mean wind speed in detail. The result shows that non-Gaussian characteristics of wind load have less influence on fatigue life of wind turbine in the area with smaller annual mean wind speeds. Whereas, the influence becomes significant with the increase of the annual mean wind speed. When the annual mean wind speeds are 7 m/s and 9 m/s at hub height of 90 m, the crack initiation lives under softening non-Gaussian wind decrease by 10% compared with Gaussian wind fields or at higher hub height. The study indicates that the consideration of the influence of softening non-Gaussian characteristics of wind inflows can significantly decrease the fatigue life, and, if neglected, it can result in non-conservative fatigue life estimates for the areas with higher annual mean wind speeds.

White-light crosslinkable milk protein bioadhesive with ultrafast gelation for first-aid wound treatment

Zhu Qinchao,Zhou Xuhao,Zhang Yanan,Ye Di,Yu Kang,Cao Wangbei,Zhang Liwen,Zheng Houwei,Sun Ziyang,Guo Chengchen,Hong Xiaoqian,Zhu Yang,Zhang Yajun,Xiao Ying,Valencak Teresa G.,Ren Tanchen,Ren Daxi 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

Background : Post-traumatic massive hemorrhage demands immediately available first-aid supplies with reduced operation time and good surgical compliance. In-situ crosslinking gels that are flexibly adapting to the wound shape have a promising potential, but it is still hard to achieve fast gelation, on-demand adhesion, and wide feasibility at the same time. Methods : A white-light crosslinkable natural milk-derived casein hydrogel bioadhesive is presented for the first time. Benefiting from abundant tyrosine residues, casein hydrogel bioadhesive was synthesized by forming di-tyrosine bonds under white light with a ruthenium-based catalyst. We firstly optimized the concentration of proteins and initiators to achieve faster gelation and higher mechanical strength. Then, we examined the degradation, cytotoxicity, tissue adhesion, hemostasis, and wound healing ability of the casein hydrogels to study their potential to be used as bioadhesives. Result : Rapid gelation of casein hydrogel is initiated with an outdoor flashlight, a cellphone flashlight, or an endoscopy lamp, which facilitates its usage during first-aid and minimally invasive operations. The rapid gelation enables 3D printing of the casein hydrogel and excellent hemostasis even during liver hemorrhage due to section injury. The covalent binding between casein and tissue enables robust adhesion which can withstand more than 180 mmHg blood pressure. Moreover, the casein-based hydrogel can facilitate post-traumatic wound healing caused by trauma due to its biocompatibility. Conclusion : Casein-based bioadhesives developed in this study pave a way for broad and practical application in emergency wound management.

Safety Assessment of Ovarian Cryopreservation and Transplantation in Nude Mice Bearing Human Epithelial Ovarian Cancer

Zhu, Gen-Hai,Wang, Sheng-Tan,Yang, Zhao-Xin,Cai, Jun-Hong,Chen, Chun-Ying,Yao, Mao-Zhong,Hong, Lan,He, Guo-Li,Yang, Shu-Ying Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9

Objective: Nude mice with orthotopic transplantation of human ovarian epithelial cancer were used to investigate screening criteria for paraneoplastic normal ovarian tissue and the security of the freezing and thawing for ovarian tissue transplantation. Methods: Expression of CK-7, CA125, P53, survivin, MMP-2/TIMP-2 in paraneoplastic normal ovarian tissues were detected by RT-PCR as well as immunohistochemistry. The tissues of the groups with all negative indicators of RT-PCR, all negative indicators of immunohistochemistry, negative expression of CK-7, CA125 and survivin, positive expression of CK-7, CA125 and survivin, cancer tissues and normal ovarian tissues of nude mice were used for freezing and thawing transplantation, to analyze overt and occult carcinogenesis rates after transplantation. Results: When all indicators or the main indicators, CK-7, CA125 and survivin, were negative, tumorigenesis did not occur after transplantation. In addition the occult carcinogenesis rate was lower than in the group with positive expression of CK-7, CA125 and survivin (P<0.01). After subcutaneous and orthotopic transplantation of ovarian tissues, rates did not change (P>0.05). There was no statistical significance among rates after transplantation of ovarian tissues which were obtained under different severity conditions (P>0.05). Conclusion: Negative expression of CK-7, CA125 and survivin can be treated as screening criteria for security of ovarian tissues for transplantation. Immunohistochemical methods can be used as the primary detection approach. Both subcutaneous and orthotopic transplantation are safe. The initial severity does not affect the carcinogenesis rate after tissue transplantation. Freezing and thawing ovarian tissue transplantation in nude mice with human epithelial ovarian carcinoma is feasible and safe.

Automatic Detection of Anomalies in Blood Glucose Using a Machine Learning Approach

Ying Zhu 한국통신학회 2011 Journal of communications and networks Vol.13 No.2

Rapid strides are being made to bring to reality the technology of wearable sensors for monitoring patients’ physiological data.We study the problem of automatically detecting anomalies in themeasured blood glucose levels. The normal daily measurements of the patient are used to train a hidden Markov model (HMM). The structure of the HMM—its states and output symbols—are selected to accurately model the typical transitions in blood glucose levels throughout a 24-hour period. The learning of the HMM is done using historic data of normal measurements. The HMM can then be used to detect anomalies in blood glucose levels being measured,if the inferred likelihood of the observed data is low in the world described by the HMM. Our simulation results show that our technique is accurate in detecting anomalies in glucose levels and is robust (i.e., no false positives) in the presence of reasonable changes in the patient’s daily routine.

The Design of Fingerprint Identification System based on Improved Binarization Algorithm

Zhu Heng-jun,Guo Ying,Zhang nan-nan,Liang Hong 보안공학연구지원센터 2014 International Journal of Security and Its Applicat Vol.8 No.6

Reversion of Multidrug Resistance by SKI-II in SGC7901/DDP Cells and Exploration of Underlying Mechanisms

Zhu, Zu-An,Zhu, Zheng-Qiu,Cai, Hong-Xing,Liu, Ying Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2

In order to investigate whether SKI-II could reverse drug resistance and its possible mechanisms, we treated SGC7901/DDP cells with SKI-II or SKI-II in combination with DDP. Then cell growth, apoptosis, micromorphological changes, and expression of SphK1, P-gp, NF-${\kappa}B$, Bcl-2 and Bax were assessed by MTT assay, flow cytometry, electron microscopy, immunocytochemistry and Western blot assay respectively. SGC7901/DDP cells were insensitive to cisplatin 2.5mg/L, but when pretreated with SKI-II, their proliferation was inhibited by cisplatin 2.5mg/L significantly, the inhibition rate increasing with time and dose. The apoptosis rate was also significantly elevated. Expression of SphK1 and P-gp was decreased significantly, Pearson correlation analysis showing significant correlation between the two (r=0.595, P<0.01). Expression of NF-${\kappa}B$ and Bcl-2 was decreased significantly,while that of Bax was increased, compared to the control group. There were significant correlations between SphK1 and NF-${\kappa}B$(r=0.723, P<0.01), NF-${\kappa}B$ and Bcl-2(r=0.768, P<0.01). All these data indicated that SKI-II could reverse drug resistance of SGC7901/DDP to cisplatin by down-regulating expression of P-gp and up-regulating apoptosis through down-regulation of SphK1. The increased apoptotic sensitivity of SGC7901/DDP to cisplatin was due to the decreasing proportion of Bcl-2/Bax via down-regulating NF-${\kappa}B$.

Characterization of the Open Reading Frame 35 of Bombyx mori Nucleopolyhedrovirus

Ying Min Zhu,Guo Hui Li,Qin Yao,Ke Ping Chen,Zhong Jian Guo 한국잠사학회 2010 International Journal of Industrial Entomology Vol.21 No.2

Open reading frame 35 (bm35) of the Bombyx mori nucleopolyhedrovirus (BmNPV) is a special gene whose homologues are only found in some group-I nucleopolyhedroviruses, suggesting that bm35 plays a specific role in the viral life cycle. This paper described the characterization of BmNPV bm35. Computerassisted sequence analysis shows that a putative RING finger motif is observed in the protein, Bm35 encoded by bm35. The coding sequence of bm35 was amplified and subcloned into the vector pET30a(+) and the (His)6-tagged fusion protein His-Bm35 was expressed in the Escherichia coli BL21 (DE3) LysS cells. The bm35 transcript and Bm35 protein were detected in BmNPV-infected BmN cells at 12~48 h post infection (p.i.) by RT-PCR and Western blot analysis using the polyclonal antibody generated by immunizing a rabbit with purified (His)6-tagged Bm35, suggesting that bm35 is synthesized in the late stage of BmNPV infection cycle. Bm35 was not a structural component associated with budded virus (BV) and occlusion derived virus (ODV). These data indicated that bm35 is a functional gene in the BmNPV life cycle.

Zn promoted Cu–Al catalyst for hydrogenation of ethyl acetate to alcohol

Ying-ming Zhu,Li Shi 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4

The additives of Zn to Cu/Al2O3 catalysts had been studied for hydrogenation of ethyl acetate to ethanol. In addition, X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), H2-temperature programmed reduction (TPR) and TEM studies were performed to characterize the catalysts. The flow reactor studies demonstrated that Zn significantly enhance the reactivity of ethyl acetate in the reaction. The nature of the Cu species on the support, the influence of Zn/Al molar ratio and time-on-stream study were also studied. Pretreatment using pure H2 at different temperatures affected the performance, while the best among the conditions tested was 573 K for 2 h. Addition of Zn influenced the particle size and dispersion of Cu in the studied system. The detected conversion of ethyl acetate reached 66.3% with a 95.3% selectivity of ethanol. This investigation of the Zn promoted Cu/Al2O3 catalyst provides a recently proposed pathway for ethyl acetate hydrogenation reaction to produce ethanol over Cu catalysts.

Characterization of the Open Reading Frame 35 of Bombyx mori Nucleopolyhedrovirus

Zhu, Ying Min,Li, Guo Hui,Yao, Qin,Chen, Ke Ping,Guo, Zhong Jian Korean Society of Sericultural Science 2010 International Journal of Industrial Entomology Vol.21 No.2

Open reading frame 35 (bm35) of the Bombyx mori nucleopolyhedrovirus (BmNPV) is a special gene whose homologues are only found in some group-I nucleopolyhedroviruses, suggesting that bm35 plays a specific role in the viral life cycle. This paper described the characterization of BmNPV bm35. Computerassisted sequence analysis shows that a putative RING finger motif is observed in the protein, Bm35 encoded by bm35. The coding sequence of bm35 was amplified and subcloned into the vector pET30a(+) and the $(His)_6$-tagged fusion protein His-Bm35 was expressed in the Escherichia coli BL21 (DE3) LysS cells. The bm35 transcript and Bm35 protein were detected in BmNPV-infected BmN cells at 12~48 h post infection (p.i.) by RT-PCR and Western blot analysis using the polyclonal antibody generated by immunizing a rabbit with purified $(His)_6$-tagged Bm35, suggesting that bm35 is synthesized in the late stage of BmNPV infection cycle. Bm35 was not a structural component associated with budded virus (BV) and occlusion derived virus (ODV). These data indicated that bm35 is a functional gene in the BmNPV life cycle.