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이백수,윤길봉,한천수 대한건축학회 2001 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.21 No.1
In this paper, prescription on the architectural standard specifications between China(CASS) and Korea(KASS) are compared focused on the part of transportation, placing, compacting and curing. According to the research, there are a lot of differences between KASS and CASS. In CASS, time limitation from discharging concrete to completing placement of concrete, transportation, placing and continuous placing time limit are provided in accordance with strength level such as below C30 and above C30. There are no provisions related to special purpose concrete in CASS.
Yin, Zhihong,Zhao, Xin,Wang, Zhun,Li, Zhen,Bai, Rui,Yang, Shanshan,Zhao, Min,Pang, Quanhai Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.10
Guanine nucleotide-binding protein subunit alpha-s ($Gn{\alpha}s$) is a small subunit of the G protein-couple signaling pathway, which is involved in the formation of coat color. The expression level and distribution of $Gn{\alpha}s$ were detected by quantitative real-time-polymerase chain reaction (qPCR), western blot, and immunohistochemistry to investigate the underlying mechanisms of coat color in white and black skin tissues of mice. qPCR and western blot results suggested that $Gn{\alpha}s$ was expressed at significantly higher levels in black mice compared with that of white mice, and transcripts and protein possessed the same expression in both colors. Immunohistochemistry demonstrated $Gn{\alpha}s$ staining in the root sheath and dermal papilla in hair follicle of mice skins. The results indicated that the $Gn{\alpha}s$ gene was expressed in both white and black skin tissues, and the expression level of $Gn{\alpha}s$ in the two types of color was different. Therefore, $Gn{\alpha}s$ may be involved in the coat color formation in mice.
A New Micromechanical Criterion for Ductile Fracture of G20Mn5QT Cast Steels Under Shear Stress
Yue Yin,Mengfei Li,Qinghua Han,Yan Lu,Jinghan Bai 한국강구조학회 2022 International Journal of Steel Structures Vol.22 No.5
A new micromechanical criterion was proposed for ductile fracture caused by shear in low stress triaxiality regions. The infl uences of both the stress triaxiality and the Lode parameter were reasonably considered. The formula of the critical plastic strain for ductile fracture by shear was deduced based on the idea that the evolution of microvoids in materials under shear stresses is a successive procedure of nucleation, growth, elongation and collapse. Six shear specimens of G20Mn5QT cast steels were tested under monotonic tension. Three confi gurations of these specimens provided diff erent combinations of the stress triaxiality and the Lode parameter. The critical void compression ratio for the void collapse was determined based on unit cell analysis and the shape of the dimples on the fracture surfaces of the test specimens. Parameters in the proposed criterion were then calibrated for G20Mn5QT cast steels based on tests and complementary fi nite element analysis of the shear specimens. Finally, diff erent fracture mechanisms of G20Mn5QT cast steels were discussed.
Slipchip Device Development in Molecular Diagnostics
Qingtian Yin,Huiwen Bai,Ruijie Li,석영웅 한국재료학회 2024 한국재료학회지 Vol.34 No.2
Slipchip offers advantages such as high-throughout, low cost, and simple operation, and therefore, it is one of the technologies with the greatest potential for high-throughput, single-cell, and single-molecule analyses. Slipchip devices have achieved remarkable advances over the past decades, with its simplified molecular diagnostics gaining particular attention, especially during the COVID-19 pandemic and in various infectious diseases scenarios. Medical testing based on nucleic acid amplification in the Slipchip has become a promising alternative simple and rapid diagnostic tool in field situations. Herein, we present a comprehensive review of Slipchip device advances in molecular diagnostics, highlighting its use in digital recombinase polymerase amplification (RPA), loop-mediated isothermal amplification (LAMP), and polymerase chain reaction (PCR). Slipchip technology allows users to conduct reliable droplet transfers with high-throughput potential for single-cell and molecule analyses. This review explores the device’s versatility in miniaturized and rapid molecular diagnostics. A complete Slipchip device can be operated without special equipment or skilled handling, and provides high-throughput results in minimum settings. This review focuses on recent developments and Slipchip device challenges that need to be addressed for further advancements in microfluidics technology.
Qingan Yin,Changhe Li,Lan Dong,Xiufang Bai,Yanbin Zhang,Min Yang,Dongzhou Jia,Runze Li,Zhan-qiang Liu 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.8 No.6
Minimum quantity lubrication (MQL) is an emerging green and resource-saving machining technique jetting minute amount lubricants and gas after mixing and atomization. However, MQL development is restricted to mineral oils because of its undegradability and threat to the environment and human health. Vegetable oils can replace mineral oils as base oil for MQL benefitting from its biodegradability and renewable property. Nevertheless, the lubrication mechanism at the tool-workpiece interface of different vegetable oils with various physicochemical properties has not been revealed systematically. In order to verify the interfacial lubrication characteristics of different vegetable oils, MQL milling experiments of AISI 1045 based on fi ve vegetable oils (cottonseed, palm, castor, soybean, and peanut oils) were carried out. The experimental results showed that, palm oil obtained the lowest milling force ( F x = 312 N, F y = 156 N), friction coeffi cient (0.78), and surface roughness values ( Ra = 0.431 μm, RSm = 0.252 mm) and the smoothest surface of workpiece. Furthermore, the physiochemical properties (composition, molecular structure, viscosity, surface tension, and contact angle) of vegetable oil were analyzed. Palm oil with high content of saturated fatty acid, high viscosity and small contact angle can form the lubricating oil fi lm with the highest strength and the largest spreading area at the tool-workpiece interface. Therefore, palm oil can achieve the optimal lubrication effect.
PP섬유 혼입 및 횡구속재 변화에 따른 고성능 콘크리트의 폭열방지에 관한 실험적 연구
황인성 ( Hwang¸ Yin-seong ),이백수 ( Li¸ Bai-shou ),이병열 ( Lee¸ Byung-yul ),양성환 ( Yang¸ Seong-hwan ),한천구 ( Han¸ Cheon-goo ) 한국구조물진단유지관리공학회 2002 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.6 No.1
This study is an experimental study on the spalling resistance of high performance concrete with PP fiber contents and material for lateral confinement. According to the results, spalling occurs to all specimens that do not contain PP fiber and it is prevented in the specimens containing PP fiber by more than 0.05% after heating, so it shows good effect on the spalling resistance. Variation of material kind for lateral confinement, metal lath shows the best effect on spalling resistance, and glass fiber and carbon fiber do not show good effect on the spalling resistance due to reduction of bond strength by high temperature. While the residual compressive strength shows about 80% of its original strength in the specimen confined laterally by PP fiber contents and metal lath, it decreases a bit in the range of 50~60% of its original strength because of reduction of the bond strength.
Deng-xiong Li,Xiao-ming Wang,Yin Tang,Yu-bo Yang,Dechao Feng,Ao Li,Fa-cai Zhang,Yun-jin Bai,Ping Han 대한비뇨의학회 2021 Investigative and Clinical Urology Vol.62 No.6
Purpose: Many studies identified that the preoperative neutrophil-to-lymphocyte ratio (PNLR) was associated with patient prognosis in non-muscle-invasive bladder cancer (NMIBC). We hypothesized that PNLR could be prognostic in patients with histological variants of NMIBC (VH-NMIBC). Materials and Methods: This retrospective study included patients with VH-NMIBC admitted at our center between January 2009 and May 2019. The best cut-off value of NLR was measured by the receiver operating characteristic curve and Youden index. The Kaplan-Meier method and Cox proportional hazard regression models were employed to evaluate the association between PNLR and disease prognosis, including recurrence-free survival (RFS), progression-free survival (PFS), cancer-specific survival (CSS), and overall survival (OS). Results: A total of 243 patients with VH-NMIBC were enrolled in our study. According to the Kaplan-Meier method results, patients with PNLR ≥2.2 were associated with poor RFS (p<0.001), PFS (p<0.001), CSS (p<0.001), and OS (p<0.001). Multivariable analyses indicated that PNLR ≥ 2.2 was an independent prognostic factor of RFS (hazard ratio [HR], 2.11; 95% confidence interval [CI, 1.57–1.83; p<0.001), PFS (HR, 2.34; 95% CI, 1.70–3.21; p<0.001), CCS (HR, 2.87; 95% CI, 1.96–4.18; p< 0.001), and OS (HR, 2.83; 95% CI, 1.96–4.07; p<0.001). Conclusions: This study identified that PNLR ≥2.2 was usually associated with a poor prognosis for patients with VH-NMIBC.