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On the Building Countermeasures of Content Bank Based on Digital Content Industry
Han Ping,Tao Zhong,Liu Xiao-lu 보안공학연구지원센터 2015 International Journal of Security and Its Applicat Vol.9 No.6
Digital content industry is the core of emerging cultural industry. If it wants to realize the transformation from “Platform is king” to “Content is king”, it needs the external technology’s support. Content and technology restrict each other and develop jointly. Both of them promote the development of the digital content industry fundamentally. This article makes an analysis of content and technology’s present situation that base on a new point of view, and analyzes digital content industry’s developing status quo and problems from the microscopic level, then it proposes the idea of “content bank” , and shows that content bank’s operating system to promote the digital content industry to develop rapidly and healthily.
DNA-Linker-Induced SurfaceAssembly of Ultra DenseParallel Single Walled Carbon Nanotube Arrays
Han, Si-ping,Maune, HareemT.,Barish, Robert D.,Bockrath, Marc,Goddard, William A. American ChemicalSociety 2012 Nano letters Vol.12 No.3
<P>Ultrathin film preparations of single-walled carbon nanotube (SWNT) allow economical utilization of nanotube properties in electronics applications. Recent advances have enabled production of micrometer scale SWNT transistors and sensors but scaling these devices down to the nanoscale, and improving the coupling of SWNTs to other nanoscale components, may require techniques that can generate a greater degree of nanoscale geometric order than has thus far been achieved. Here, we introduce linker-induced surface assembly, a new technique that uses small structured DNA linkers to assemble solution dispersed nanotubes into parallel arrays on charged surfaces. Parts of our linkers act as spacers to precisely control the internanotube separation distance down to <3 nm and can serve as scaffolds to position components such as proteins between adjacent parallel nanotubes. The resulting arrays can then be stamped onto other substrates. Our results demonstrate a new paradigm for the self-assembly of anisotropic colloidal nanomaterials into ordered structures and provide a potentially simple, low cost, and scalable route for preparation of exquisitely structured parallel SWNT films with applications in high-performance nanoscale switches, sensors, and meta-materials.</P>
An Epigenetic Mechanism Underlying Doxorubicin Induced EMT in the Human BGC-823 Gastric Cancer Cell
Han, Rong-Fei,Ji, Xiang,Dong, Xing-Gao,Xiao, Rui-Jing,Liu, Yan-Ping,Xiong, Jie,Zhang, Qiu-Ping Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.10
The epithelial to mesenchymal transition (EMT) is a key step during embryonic morphogenesis and plays an important role in drug resistance and metastasis in diverse solid tumors. We previously reported that 48 h treatment of anti-cancer drug doxorubicin could induce EMT in human gastric cancer BGC-823 cells. However, the long term effects of this transient drug treatment were unknown. In this study we found that after 48 h treatment with $0.1{\mu}g/ml$ doxorubicin, most cells died during next week, while a minor population of cells survived and formed colonies. We propagated the surviving cells in drug free medium and found that these long term cultured drug survival cells (abbreviated as ltDSCs) retained a mesenchymal-like cell morphology, and expressed high levels of EMT-related molecules such as vimentin, twist and ${\beta}$-catenin. The expression of chromatin reprogramming factors, Oct4 and c-myc, were also higher in ltDSCs than parental cells. We further demonstrated that the protein level of p300 was upregulated in ltDSCs, and inhibition of p300 by siRNA suppressed the expression of vimentin. Moreover, the ltDSCs had higher colony forming ability and were more drug resistant when compared to parental cells. Our results suggested that an epigenetic mechanism is involved in the EMT of ltDSCs.
Han Zhang,Guangliang Liu,Haiyan Song,Chunxia Chen,Fuqin Han,Ping Chen,Zhixi Zhao,Shaozheng Hu 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.10
Direct synthesis of H2O2 and in situ oxidative desulfurization of model fuel over Au/Ti-HMS and Au/TS-1 catalysts has been comparatively investigated in water or methanol. Maximum amount (82%) of active Au0 species for H2O2 synthesis was obtained. Au/Ti-HMS and Au/TS-1 exhibited the contrary performances in H2O2 synthesis as CH3OH/H2O ratio of solvent changed. H2O2 decomposition and hydrogenation in water was inhibited by the introduction of methanol. Effect of O2/H2 ratio on H2O2 concentration, H2 conversion and H2O2 selectivity revealed a relationship between H2O2 generation and H2 consumption. The highest dibenzothiophene removal rate (83.2%) was obtained over Au/Ti-HMS in methanol at 1.5 of O2/H2 ratio and 60 oC. But removal of thiophene over Au/TS-1 should be performed in water without heating to obtain a high removal rate (61.3%). Meanwhile, H2 conversion and oxidative desulfurization selectivity of H2 were presented.
Chen, Han-Ping,Yuan, Yu,Yu, Bo,Ahn, Jaesoo,McIntyre, Paul C.,Asbeck, Peter M.,Rodwell, Mark J. W.,Taur, Yuan IEEE 2012 IEEE transactions on electron devices Vol.59 No.9
<P>This paper presents a detailed analysis of the multifrequency capacitance–voltage and conductance–voltage data of <TEX>$\hbox{Al}_{2}\hbox{O}_{3}/\hbox{n-InGaAs}$ </TEX> MOS capacitors. It is shown that the widely varied frequency dependence of the data from depletion to inversion can be fitted to various regional equivalent circuits derived from the full interface-state model. In certain regions, incorporating bulk-oxide traps in the interface-state model enables better fitting of data. By calibrating the model with experimental data, the interface-state density and the trap time constants are extracted as functions of energy in the bandgap, from which the stretch-out of gate voltage is determined. It is concluded that the commonly observed decrease of the 1-kHz capacitance toward stronger inversion is due to the increasing time constant for traps to capture majority carriers at the inverted surface.</P>
Zhang, Han,Liu, Guangliang,Song, Haiyan,Chen, Chunxia,Han, Fuqin,Chen, Ping,Zhao, Zhixi,Hu, Shaozheng Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.10
Direct synthesis of $H_2O_2$ and in situ oxidative desulfurization of model fuel over Au/Ti-HMS and Au/TS-1 catalysts has been comparatively investigated in water or methanol. Maximum amount (82%) of active $Au^0$ species for $H_2O_2$ synthesis was obtained. Au/Ti-HMS and Au/TS-1 exhibited the contrary performances in $H_2O_2$ synthesis as $CH_3OH/H_2O$ ratio of solvent changed. $H_2O_2$ decomposition and hydrogenation in water was inhibited by the introduction of methanol. Effect of $O_2/H_2$ ratio on $H_2O_2$ concentration, $H_2$ conversion and $H_2O_2$ selectivity revealed a relationship between $H_2O_2$ generation and $H_2$ consumption. The highest dibenzothiophene removal rate (83.2%) was obtained over Au/Ti-HMS in methanol at 1.5 of $O_2/H_2$ ratio and $60^{\circ}C$. But removal of thiophene over Au/TS-1 should be performed in water without heating to obtain a high removal rate (61.3%). Meanwhile, $H_2$ conversion and oxidative desulfurization selectivity of $H_2$ were presented.