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- 저자 : ( Shi Jun Kim ) (검색결과 168 건)
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金時俊 서울대학교 동아문화연구소 1979 東亞文化 Vol.16 No.-
It was written at the Mao Shi prefaces (毛詩序) that Shi Jing was divided into two groups; the Zheng Poem and the Bian Poem. According to this, many scholars published various assertions on how to distinguish the Zheng Poem from the Bian Poem in Shi Jing. Conseguently, these assertions were classified into four sorts. 1) Classification by the chronological order according to the political rise and fall 2) Distinction between eulogy and satire 3) Distinction the Poem which was accompanied by music from the poem which was not accompanied by it, 4) Classification by the style of the poem My study on each assertion leads to the following conclusion: 1) Although those scholars who made the first assertion defined that Shi Jing was published by the chronological order and they distinguished the Zheng Poem from the Bian poem by the table of contents, it is proved that Shi Jing was not published by the chronological order. 2) Those scholars who made the second assertion concluded that Shi-Jing was distinguished between eulogy and satiry at every prologue in Mao Shi and that the Zheng poem and the Bian Poem could be divided into eulogy or satire accordingly. But it is proved herein that the distinction eulogy from satire in Mao Shi prefaces was possible by the country and chronology without the definite standard even though the contents of the poem were the same. 3) Those scholars who made the third assertion divided Shi Jing into two parts. One that was accompanied by music was called the Zheng Poem and the other that was accompanied by music was called the Bian Poem. But it is proved that all of Shi Jing were accompanied by music 4) Those who made the fourth assertion distinguished between the Zheng Poem and the Bian Poem by the style of the Poem. But looking into the style, it is proved that the distinction between the Zheng Poem and the Bian Poem is the style itself. Thus, the above classifications seem to be unreasonable so far. Then, why did these assertions come to rise? These assertions were due to the Han scholars who regarded the poem as a remonstration. They attempted to classify the Zheng Poem as the poem of admonition and the Bian poem as that of warning. But they did not succeed in it.
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( Yu Kyung Lee ),( Eun Young Park ),( Shi Won Kim ),( Ji Yeon Son ),( Tae Hyung Kim ),( Won Gu Kang ),( Tae Chun Jeong ),( Kyu Bong Kim ),( Seung Jun Kwack ),( Jae Won Lee ),( Suh Mann Kim ),( Byung M 영남대학교 약품개발연구소 2015 영남대학교 약품개발연구소 연구업적집 Vol.25 No.-
The aim of this study was to investigate urinary metabolomics profiles associated with cadmium (Cd)-induced nephrotoxicity and their potential mechanisms. Metabolomic profiles were measured by high-resolution 1H-nuclear magnetic resonance (NMR) spectroscopy in the urine of rats after oral exposure to CdCl2 (1, 5, or 25 mg/kg) for 6 wk. The spectral data were further analyzed by a multivariate analysis to identify specific urinary metabolites. Urinary excretion levels of protein biomarkers were also measured and CdCl2 accumulated dose-dependently in the kidney. High-dose (25 mg/kg) CdCl2 exposure significantly increased serum blood urea nitrogen (BUN), but serum creatinine (sCr) levels were unchanged. High-dose CdCl2 (25 mg/kg) exposure also significantly elevated protein-based urinary biomarkers including osteopontin, monocyte chemoattractant protein-1 (MCP-1), kidney injury molecules-1 (Kim-1), and selenium-bingding protein 1 (SBP1) in rat urine. Under these conditions, six urinary metabolites (citarate, serine, 3-hydroxyisovalerate, 4-hydroxyphentllactate, dimethylamine, and betaine) were involved in mitochondrial energy metabolism. In addition, a few number of amino acids such as glycine, glutamate, tyrosine, proline, or phentlalanine and carbohydrate (glucose) were altered in urine afrer CdCl2 exposure. In particular, the metabolites involved in the glutathione biosynthesis pathway, including cysteine, serine, methionine, and glutamate, were markedly decreased compared to the control. Thus, these metabolites are potential biomarkers for detection of Cd-induced nephrotoxicity. Our results further indicate that redox metabolomics pathways may be associated with Cd-mediated chronic kidney injury. These findings provide a biochemical pathway for better understanding of cellulat mechanism underlying Cd-induced renal injury in hunmans.
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水稻施肥水準別 乾物生産 및 消費水量의 變異에 關한 硏究
金始源,金基駿,金光鎬 건국대학교 1981 學術誌 Vol.25 No.1
The experiment was conducted to find out the dry matter production of rice plant, the consumptive use of irrigated water and the relationship between them in relation to rice varieties and nitrogen levels in paddy field. Two rice varieties, Jinheung and Suweon 258, were planted and cultivated under the condition of three nitrogen levels, 8, 16 and 24 kg per 10 are, during 1980 rice growing season. The results obtained could be summarized as follows : 1.The daily mean temperature during the main rice growing stages in this year was much lower than that of normal. Total precipitation was 167 mm less, daily mean sunshine hour was 2.3 hours short and pan evaporation was 111 mm less from June to September compared with them of normal year, mean value from 1931 to 1960, respectively. 2.Suweon 258 with shorter plant height and much tillering ability showed more dry matter weight of rice plant than that of Jinheung, which had longer plant height and less tillering ability, through the experimental period except the period after early maturing stage. Plant height, number of tillers and dry matter weight of the rice plant grown under the condition of 8 kg/10a nitrogen were much less than those of rice plant under 16 kg/10a and 24 kg/10a nitrogen, but the differences between the rice plants grown under 16 and 24 kg/10a nitrogen application were almost negligible through the rice growing period. 3.Suweon 258, the less tolerant variety to low temperature condition, showed poor grain yield mainly due to the lower percentage of matured grain and lower 1000-grain weight, but the Japonica variety, Jinheung, showed higher grain yield than that of Suweon 258. The nitrogen response to grain yield of Suweon 258 was not found because of low temperature damage during the rice growing period, but Jinheung showed more grain yield at 16 and 24 kg/10a nitrogen levels than that of 8 kg/10a plot. 4.Total amount of evapotranspiration during experimental period was more in plots of Suweon 258 and higher nitrogen level, showed more dry matter weight through the rice growing period. But the difference of total evapotranspiration between treatments was much less than that of dry matter weight through the whole experimental period. 5.The amount of evapotranspiration at each growing stage showed more in plots of treatment shown higher dry matter production, and the evapotranspiration and dry matter increment of rice plant were maximum in early of August through the whole treatments. 6.The ratio of evapotranspiration to pan evaporation also showed higher value in plots of treatment shown higher dry matter production, and this ratio was maximum in middle of August during experimental period in whole treatment plots. 7.K-value in Blaney and Criddle formula in this year was lower than normal year, and K-value and the coefficient for consumptive water use (Kc-value) showed higher in plots of treatment shown more dry matter production. K- and Kc-value were highest in middle of September abnormally because of lower daily mean temperature in this year. 8.The modified coefficient for consumptive water use, which was calculated from data collected through the country including this study, showed higher value than current standard coefficient through the whole rice growing period except early of June.
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조재환,김태균,박시현,박준형 한국농업정책학회, 한국축산경영학회 2003 농업경영정책연구 Vol.30 No.3
This paper analyzes urban residents' preference on rural tourism using a survey data. The results show that even though urban residents are unaware of rural tourism, people who have experienced rural tourism set a high value on it. Urban residents are willing to pay about 93,600Won for rural tourism. These results indicate that there is a lot of potential demand for rural tourism. The results of this paper could be an important information to develop the rural tourism.
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Captopril과 Nifedipine 병합요법의 강압효과에 관한 임상적 연구
이영수,문언수,김준호,공수정,정시진,주용진,정상만 건국대학교 의과학연구소 1993 건국의과학학술지 Vol.3 No.-
Background: The hypotensive effect of captopril(angiotensin converting enzyme inhibitor) and nifedipine(calcium channel blocker) was studied. Method: Captopril(75mg) and nifedipine(30mg) were administered in 30 hypertensive adults during twelve weeks after a week observation for washout with stepwise increments of the dose according to the patient's blood pressure in every two weeks. Result: The supine blood pressure were decreased from 169.5±22.3/104.0±20.3 mmHg to 130.4±21.3/82.4±19.5mmHg at the end of twelve weeks during therapy.(p<0.05) The standing blood pressure were also decreased conferrably and to the some lower level. Hematologic examination and blood chemistry revealed no discernible abnormal findings before and after the treatment. During the period of the study a few probably drug-related symptom such as cough and headache, gastrointestinal disturbance developed but not troublesome enough to administering. Conclusion: Captopril and nifedipine regimen is well tolerated and effective in the treatment of hypertensive patients.
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Kim Si-Ho,Hong Jin Yeong,Bae Seongman,Lee Hojin,Wi Yu Mi,Ko Jae-Hoon,Kim Bomi,Joo Eun-Jeong,Seok Hyeri,Shi Hye Jin,Yoo Jeong Rae,Hyun Miri,Kim Hyun ah,Jang Sukbin,Mun Seok Jun,Kim Jungok,Kim Min-Chul 대한의학회 2022 Journal of Korean medical science Vol.37 No.18
Background: Coronavirus disease 2019 (COVID-19) is often accompanied by secondary infections, such as invasive aspergillosis. In this study, risk factors for developing COVID-19- associated pulmonary aspergillosis (CAPA) and their clinical outcomes were evaluated. Methods: This multicenter retrospective cohort study included critically ill COVID-19 patients from July 2020 through March 2021. Critically ill patients were defined as patients requiring high-flow respiratory support or mechanical ventilation. CAPA was defined based on the 2020 European Confederation of Medical Mycology and the International Society for Human and Animal Mycology consensus criteria. Factors associated with CAPA were analyzed, and their clinical outcomes were adjusted by a propensity score-matched model. Results: Among 187 eligible patients, 17 (9.1%) developed CAPA, which is equal to 33.10 per 10,000 patient-days. Sixteen patients received voriconazole-based antifungal treatment. In addition, 82.4% and 53.5% of patients with CAPA and without CAPA, respectively, received early high-dose corticosteroids (P = 0.022). In multivariable analysis, initial 10-day cumulative steroid dose > 60 mg of dexamethasone or dexamethasone equivalent dose) (adjusted odds ratio [OR], 3.77; 95% confidence interval [CI], 1.03–13.79) and chronic pulmonary disease (adjusted OR, 4.20; 95% CI, 1.26–14.02) were independently associated with CAPA. Tendencies of higher 90- day overall mortality (54.3% vs. 35.2%, P = 0.346) and lower respiratory support-free rate were observed in patients with CAPA (76.3% vs. 54.9%, P = 0.089). Conclusion: Our study showed that the dose of corticosteroid use might be a risk factor for CAPA development and the possibility of CAPA contributing to adverse outcomes in critically ill COVID-19 patients.
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