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최명훈 ( Myeung Hun Choi ),전지현 ( Jie Hyun Jeon ),김애리 ( Ae Ree Kim ),오칠환 ( Chil Hwan Oh ),송해준 ( Hae Jun Song ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.3
Primitive neuroectodermal tumors (PNETs) are malignant, round-cell sarcomas which exhibit primitive neuronal differentiation. They usually arise in deep soft tissues, but occasionally bones and visceral organs are affected. In general, PNET presents as rapidly-growing, deeply located masses measuring 5~10 cm at their greatest diameter. Superficially located cases do occur but are rare. The typical PNET is composed of sheets or lobules of small round cells containing darkly-staining, round or oval nuclei. The cytoplasm is indistinct except in areas where the cells are more mature and elongated hair-like cytoplasmic extensions coalesce to form rosettes. We herein report a case of PNET that arose from subcutaneous tissue of the buttock in a 31-year-old woman. (Korean J Dermatol 2007; 45(3):275~278)
최명훈 ( Myeung Hun Choi ),전지현 ( Jie Hyun Jeon ),손상욱 ( Sang Wook Son ),송해준 ( Hae Jun Song ),오칠환 ( Chil Hwan Oh ) 대한피부과학회 2006 大韓皮膚科學會誌 Vol.44 No.12
Nodular fasciitis is a benign, reactive, myofibroblastic, proliferative process of unknown etiology. It presents as a solitary, painless, rapidly-growing nodule over several weeks` duration. The condition is self-limiting, and proper diagnosis is essential to avoid unnecessary aggressive treatment. Diagnosis is often a challenge because nodular fasciitis may be confused with a malignant tumor due to its aggressive clinical behavior and histological features. It is most commonly located on the extremities and then the trunk. Such lesions also usually occur in middle age and are rarely diagnosed in childhood. We report a case of recurrent nodular fasciitis that arose from subcutaneous tissue on the back of a pediatric patient. (Korean J Dermatol 2006;44(12):1457~1459)
Blaschko 선을 따라 발생한 선천멜라닌세포모반 1예
최명훈 ( Myeung Hun Choi ),손수빈 ( Soo Bin Son ),송해준 ( Hae Jun Song ),오칠환 ( Chil Hwan Oh ) 대한피부과학회 2008 大韓皮膚科學會誌 Vol.46 No.12
Nevus spilus, also known as speckled lentiginous nevus, is a relatively common cutaneous lesion that is characterized by multiple pigmented macules within a pigmented patch. It may be congenital or acquired, and it can show the histological features of congenital melanocytic nevus (CMN). The possible relationship between nevus spilus and CMN has been contentious. We report a case of a congenital nevus that followed the line of Blaschko and clinically manifested as nevus spilus, but showed the histological features of CMN. (Korean J Dermatol 2008;46(12):1654∼1656)
최지훈(Ji Hun Choi),심혁(Hyuk Sim),이재훈(Jae Hoon Li),이명수(Myeung Su Lee),오석규(Soek Kyu Oh),김태현(Tae Hyeon Kim),박병현(Byoung Hyun Park),안선호(Seon Ho Ahn),송주흥(Ju Hung Song) 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.3
The 55 years old male patient, undergoing maintenance hemodialysis, was admitted on our department because of painful swelling on left knee joint. At 19th hospital day, he complained of severe dyspnea. He had a large amount of pleural effusion of the left chest that was shown to be hemothorax by thoracentesis. After closed thoracostomy, about amount of 3,000 mL of blood was drained and bleeding was sustained from pleural cavity, and then emergency thoracotomy was done. We cannot find any bleeding focus in thoracic cavity, but oozing blood was seen on entire inner thoracic cavity. He had no previous invasive procedure or history of trauma before 6 months. We think that hemothorax may be developed because of defected coagulopathy and increased bleeding tendency due to platelet dysfunction in renal failure patient. Immediately thoracotomy and cryoprecipitate were helpful for this patient. We report a rare case of spontaneous hemothorax in a maintenance hemodialysis patient with literature review.
경증 및 중등도의 한국인 여드름 환자에서 1% Nadifloxacin 크림(Nadixa(R))의 유효성 및 안전성 평가
최원준 ( Won Jun Choi ),김광중 ( Kwang Joong Kim ),김낙인 ( Nack In Kim ),계영철 ( Young Chul Kye ),서대헌 ( Dae Hun Suh ),이주흥 ( Joo Heung Lee ),김명남 ( Myeung Nam Kim ),이은소 ( Eun So Lee ),이주희 ( Ju Hee Lee ),노영석 ( You 대한피부과학회 2010 大韓皮膚科學會誌 Vol.48 No.8
Background: Antimicrobials have been a mainstay of inflammatory acne treatment for more than 30 years. However, antibiotic-resistant propionibacteria had been isolated with increased frequency, and associated with failure to respond to antibiotic therapy. Objective: The aim of this study was to investigate the clinical efficacy and tolerance of 1% nadifloxacin cream. Methods: In the final analysis, 197 patients with mild to moderate facial acne vulgaris were enrolled. The patients were instructed to apply 1% nadifloxacin cream twice daily to the affected skin after washing the face. Following 2 and 4 weeks of treatment, patients were observed for clinical response: number of the acne lesions, Korea acne grading system (KAGS), global improvement, and occurrence of adverse reactions. Results: During 4 weeks of treatment, nadifloxacin caused significant reduction in the number of inflamed papulo-pustular lesions and open/closed comedones. In addition, significant reduction of KAGS was observed. About 96% of patients showed clinical improvement in the overall evaluation of the therapeutic effect by physicians. All reported adverse events were mild. Conclusion: This study shows that 1% nadifloxacin cream can be an effective and safe treatment for mild to moderate acne vulgaris. (Korean J Dermatol 2010;48(8):665~671)
횡문근 융해증과 동반된 갑상선 중독성 주기성 마비 1예
권경희,이창훈,최경숙,백승훈,이명수,박병현,조정구 대한내과학회 2004 대한내과학회지 Vol.66 No.2
갑상선 항진증에서 횡문근 융해증은 아주 드물게 동반되며 근효소의 상승 또한 드물다. 갑상선 중독성 마비는 여러 선생인자에 의해 유발될 수 있고 마비 당시 저칼륨혈증을 자주 동반한다. 저자들은 갑상선 중독성 주기성 마비로 내원한 23세 남자 환자에서 저칼륨혈증과 하지마비가 회복되는 과정에서 일시적인 횡문근 융해증을 보인 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Hyperthyroidism has been associated with changes in muscle function such as thyrotoxic myopathy, thyrotoxic periodic paralysis and thyroid opthalomopathy, but rarely rhabdomyolysis. Usually serum creatinine kinase is either normal or low in Hyperthyroidism. Only 3 reports described association between rhabdomyolysis and Hyperthyroidism, no previous literatures have thyrotoxic periodic paralysis associated rhadbomyolysis. Patients with hypokalemic periodic paralysis sometimes elevated serum muscle protein during recovery from paralytic attack, but the mechanism was not well known. We report a patient who presented with clinical feature of thyrotoxic periodic paralysis and increasing serum CK, myoglobin during recovery from paralysis.