한국(韓國)GSK 상임고문최현식(常任顧問崔賢植)의 기업활동(企業活動)과 경영이념(經營理念)

박광서 ( Kwang Sur Park ),최승현 ( Seung Hyun Choi ) 아시아.유럽미래학회 2006 유라시아연구 Vol.3 No.2

The aims of this paper are to review Mr. Choi Hyun Sik``s business activities and analysis of his management thoughts. Mr. Choi Hyun Sik is now a general advisor of Galxo Smith Cline(GSK) Korea, one of the biggest pharmatical company in the world. And he is one of the toppest chief executive officer in Korea. He was passed as a semi-salesman, one of 3D jobs at that time, by the Choong Wae Pharamatical Corporation in 1966 and he met Mr. Lee Chong Ho who was a section chief of planning and management section anf he is now chairman of the corporation. He worked hard with chairman Lee. At last he promoted as a CEO of Choong Wae Pharmatical Corporation in 1998 and Vice Chairman of the Company in 2004. After 38 years services, he resigned from CW in 2004. At the same time, He was selected as a general advisor of GSK Korea(President Mr. Kim Jin Ho) on April 2004. As a GA of GSK Korea, As a matter of fact, Mr. Choi concertrate into his best efforts as the fellowing points; ● Focus an execution of plan. ● Develop new strategic business opportunities ● Strengthen partnership with external stakeholders. ● Optimize commercial structure and capability ● Improve working capital management & operational excellence ● Build organizational capabilities to support growth. ● Develop people pipeline, and etc. And last, his management thoughts and stratagies are 5S and 5C. That is, 5S means Speed, System, Simplicity, Strategy and Spurt. On the other hand, 5C are Creation, Credit, Competition, Customer and Communication.

국산 Lidocaine 알칼리화를 위한 Bicarbonate 혼합시 침전유발 최소량에 대한 고찰

이선호,김현수,곽인숙,안원식,최관호,김광민,손민제 대한마취과학회 2000 Korean Journal of Anesthesiology Vol.39 No.5

Background : When local anesthetics for regional anesthesia is used, usually small amounts of bicar-bonate are added for rapid onset. This addition gives the mixed solution a more alkaline pH. The following result is an increased unionized form of the local anesthetic and rapid penetration of the drug into tiissue. Unfortunately, no data about adequate mixing volumes of domestic lidocaine and bicarbonate is available. Methods : We examined six mixing pairs of two kinds of 2% lidocaines and three kinds of 8.4% bicarbonates for minimum volumes of bicarbonate to cause a precipitation of 2% 20 ml lidocaine. Results : The mean volumes of bicarbonate to cause precipitation were 1.54 ml for Kwang-Myung lidocaine with Kwang-Myung bicarbonate, 2.90 ml for Kwang-Myung lidocaine with Dae-Won bicarbonate, 2.73 ml for Kwang-Myung lidocaine with Je-Il bicarbonate, 0.97 ml for Je-Il lidocaine with Kwang-Myung bicarbonate, 1.26ml for Je-Il lidocaine with Dae-Won bicarbonate and 1.39 ml for Je-Il lidocaine with Je-Il bicarbonate. Conclusions : We conclude that the Kwang-Myung lidocaine and the Je-Il lidocaine could cause precipitation when mixing with a smaller bicarbonate volume than foreign textbook recommended. (Korean J Anesthesiol 2000; 39: 726-729)

전국 10개 종합병원 중환자실 환자의 직장내 Vancomycin-resistant Enterococci(VRE) 보균율, 보균의 위험요인 및 유전적 다양성 조사

정희진,송준영,엄중식,김우주,최선주,최정현,이혁,정문현,이광미,신동현,손보라,최종성,우흥정,권정아,이경원,최강원,박승철 대한감염학회 2002 감염 Vol.34 No.5

유방암과 관련된 부수종양성 Stiff-Person Syndrome 1예

방현,이상암,최은정,김광국,박성혜 대한신경과학회 1999 대한신경과학회지 Vol.17 No.5

차륜주행충격에 의한 빗살형 교량 신축이음장치 구조물의 과도진동해석

최영휴,김현욱,김광영 國立 昌原大學校 産業技術硏究所 1998 産技硏論文集 Vol.12 No.-

In this paper we derive relations which describe the geometry and kinematics of contact between the travelling wheel and stepped comb joint. From which we can obtain the impulse, impulsive force and its time interval due to travelling wheel impact which can not be taken from Carter's model or Newland and Cassidy's. The calculated transient responses of the comb joint structure to travelling wheel impact reveals that the proposed wheel contact model and Carter's give very similar results but Newland Cassidy's model make a quite different results from the others.

주요우울증 환자의 Interleukin-1β, -2, -6 생산성과 혈청 농도의 변화 및 시상하부-뇌하수체-부신피질축 기능의 상관성

최소현,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.3

주요우울증의 면역기능 이상과 HPA axis 사이의 관계를 규명하고자 본 연구를 시행하였다. DSM-Ⅲ-R 진단기준에 의해 주요우울증으로 진단된 16명의 여러 환자를 대상군으로 하고 대상군과 연령을 일치시킨 16명의 여자를 대조군으로 선택하였다. Basal cortisol 농도와 IL-1β, IL-2, IL-6 생산성 및 형청농도를 두군에서 각각 측정하여 비교하였다. 또한 주요우울증군에서 IL-1β, IL-2, IL-6 생산성 및 혈청농도와 basal cortisol 농도, post-DST cortisol 간의 상관관계를 알아보았다. 그 결과는 다음과 같다. 1) 주요우울증군의 basal cortisol 농도14.4±4.6㎍g/dl, 대조군은 10.1±5.2㎍/dl로 주요우울증군이 정상대조군보다 유의하게 높았다(t=2.47 : df=30, p〈0.05). 2) IL-2 생산성은 주요우울증군 1747.3±387.9pg/ml, 정상대조군 2520.2±884.1pg/ml로 주요우울증군이 대조군보다 유의하게 낮았다(t=-3.08 : df=30, p〈0.05). IL-1β 생산성과 IL-6 생산성은 양군간에 유의한 차이가 없었다. 3) IL-2 혈청농도는 주요우울증군 16명중 12명(75%), 정상대조군 16명중 10명(62.5%)에서 측정이 가능하였으며, 주요우울증군 109.3±22.8pg/ml, 정상대조군 143.8±72.0pg/ml,로 양군간에 유의한 차이는 없었다. IL-1β혈청농도는 양군에서 각각 3명씩 검출이 가능하였고, IL-6 혈청농도는 양군 모두에서 검출되지 않았다. 4) 주요우울증군에서 IL-2 생산성과 post-DST cortisol 농도사이에 유의한 역상관관계가 있었으며 (r=-0.89), IL-2 혈청농도와 post-DST cortisol 농도사이에 유의한 역상관관계가 있었다(r=-0.97). 주요우울증군에서 IL-2 혈청농도와 basal cortisol 농도사이에 유의한 역상관관계가 있었으나(r=-0.65), IL-2 생산성과 basal cortisol 농도사이에 유의한 상관관계는 없었다. 주요우울증군에서 IL-1β, IL-6 생산성과 basal cortisol 농도, post-DST cortisol 농도 사이에 유의한 상관관계는 없었다. 이러한 결과들은 주요우울증에서 면역기능이 저하되어있고 이러한 면역기능저하에 HPA axis 활성화가 관련되어 있다는 가설에 부가적인 자료로 제시될 수 있겠다. The present study was carried out in order to investigate the relationship between immune function and the activity of hypothalamic-pituitary-adrenal(HPA) axis is patients with major depression. The subjects were 16 female major depressives and 16 female healthy controls. We measured mitogen-induced production of IL-1β, IL-2, IL-6 and serum level of IL-1β, IL-2, IL-6 and basal plasma cortisol levels at 8 : 00 a.m. We measured post-DST(dexamethasone suppression test) cortisol levels in 16 major depressive. The results were as follows : 1) Basal cortisol level was significantly higher in the patients with major depression than in the healthy controls(14.4±4.6㎍g/dl, 10.1±5.2㎍/dl, respectively, p〈0.05). 2) IL-2 production was significantly lower in the patients with major depression than in the healthy controls(1747.3±387.9pg/ml, 2520.2±884.1pg/ml, respectively, p〈0.05). There were no significant differences in IL-1β and IL-6 production between the patients with major depression and the healthy controls. 3) Serum level of IL-2 was detectable in 12 to 16 patients with major depression and in 10 of 16 healthy controls. There was no significant difference in serum level of IL-2 between two groups. Serum level of IL-1β was detectable in 3 of 16 patients with major depression and of 16 healthy controls. We could not detect serum level of IL-6 in both groups. 4) There was significant negative correlation between IL-2 production and post-DST cortisol level(r=-0.89) in the 16 patients with major depression. There was significant negative correlation between serum level IL-2 and post-DST cortisol level(r=-0.97) in the 12 patients with major depression. There was significant negative correlation between serum level IL-2 and basal cortisol level(r=-0.65) in the 12 patients with major depression. But there was no significant correlation between IL-2 production and basal cortisol level in the 16 patients with major depression. These finding suggest that immune function is decreased in major depression and the decreased immune function is highly related to the hyperactivity of the HPA axis.

企業到産豫測에 있어서 現金흐름 情報의 有用性에 관한 實證的 硏究

崔光鉉,姜鎭守 영남이공대학 1995 論文集 Vol.24 No.-

The debate of accrual basis and cash flow reporting is one of the most representatives in the accounting literature. In special, many empirical studies argue that cash flow information has the additional predictive ability in predicting business failure. Accordingly, this study is to test the predictive ability of business failure by cash flow information. In order to achieve the purpose, two hypotheses are tested by multiple discriminant analysis and laboratory experiment method. Sixty samples were selected in the listed firms from 1982-1990. Thirty failure companies of them were matched by thirty non-failure companies. The results of the study are as follows: 1. The model that includes a cash flow information has superior predictive ability to the model that cash flow information is excluded. 2. The combined model that includes cash flow and financial ratios has better discriminant ability than the seperate models:one using the financial ratios and one using cash flow ratios.

소록도 官舍施設의 建築的 特性에 관한 硏究

최인환,정준현,손광제 대구대학교 과학기술연구소 1998 科學技術硏究 Vol.5 No.4

This study is to analyze the architectural characteristics of official houses in Sorok Island. On twenty official house planes, which were constructed during 1927-1940, were surveyed and analized about house type, plane construction style and unit space scale. In the result of this study, first, official house type in Sorok Island was classified into multi-family type and one-family type, plane construction style was classified into the wooden verandah style, compact style and corridor style of the original housing form of Japanese. Second, unit plane was composed mainly of 2∼3 TADANII and an ONDOL room, stand-up kitchen style, bathroom, toilet etc. and added living room of Westem Style in the large scale plane. Third, for the seperation of rooms HUSIMA(wooden sliding doors) had been installed, and TADANII size was used 「Kyung Kahn」 scale of Japanes. In the unit space scale, multi-fanuly type is smaller size than Japanese house, and one-family type is common size.

서울거주 일반성인의 수면양상의 관한 연구

최소현,서광윤,김 인 大韓神經精神醫學會 1992 신경정신의학 Vol.31 No.2

The purpose of this study was to investigate the sleep patterns of the general adult population. The subjects of this study were 1,049 general adults in Soul and this study was performed from March 1990 to July 1990. The results were as follows ; 1) The mean value for sleep length was 6.42±1.41 hours and there were no significant sex difference. In the above 51-year-old age group, sleep length was significantly shorter compared with the other two age groups(p<0.05), 202(19.3%) reported sleeping more than 8 hours and 847(80.7%) reported sleeping less than 8 hours. 2) The mean value for sleep latency was 23.40±23.03 minutes and there were no significant sex difference. In the above 51-year-old age group, sleep latency was longer than the other two age groups(p<0.05). The mean value for sleep latency in the group of respondents who complained difficulty falling asleep(DFA) was 26.85±25.51 minutes and in the group of respondents who did not complain difficulty falling asleep less than 8 hours. 2) The mean value for sleep latency was 23.40±23.03 minutes and there were no significant sex difference. In the above 51-year-old age group, sleep latency was longer than the other two age groups(p<0.05). The mean value for sleep latency in the group of respondents who complained difficulty falling asleep(DFA) was 26.85±5.51 minutes and in the group of respondents who did not complain difficulty falling asleep was 17.64±24.31minutes. The former was significantly longer than the latter(p<0.000l). 3) The time of awakening was earlier than the other two age groups (p<0.05). The mean value for the time of awakening in the group of respondents who complained early morning awakening was 5.41±1.20hrs. and in the group of respondents who did not complain early morning awakening was 5.52±1.02hrs. There were no significant difference bet ween the two groups. 4) 654(62.3 % ) complained difficulty falling asleep(DFA), 759(72.4%) complained broken sleep (BS), and 422(40.2%) complained early morning awakening(EMA). Broken sleep was more common in females than males (p<0.05) and early morning awakening was more common in above 51-year-old age group(p<0.05). 5) 301(28.7%) had a nap and the frequency of nap was significantly more in the above 51-year-old age group (p<0.000l). 6) The number of subjects who experienced daytime drowsness were significantly more in the 18-30-year-old age group than the other two age groups(P<0.000l). Snoring was significantly more frequent in the above 51-year-old age group (p<C0.005) and in the males than the females(p<0.005). 7) Of the total sample, 428(40.8 %) reported nightmares. 399(38.0%) reported sleeptalking. 178(17.0%) reported bruxism. and 24(2.3%) reported sleepwalking. Nightmares was more common in the 18-30-year-old age group(p<0.0l).

우리나라 창업 경영교육의 현황과 발전방안 : Current Status and Future Direction

崔光鉉 영남이공대학 1999 論文集 Vol.28 No.-

New enterprises are a vital source of employment. In Korea, the entrepreneurship education for promoting the entrepreneurship has been rapidly proceeded in recent years, however, entrepreneurship programs and courses are not well-prepared This paper is to examine the current status and to propose the future direction of the entrepreneurship education in Korea. Through the analysis and examination of an entrepreneurship education of the U.S. Universities and Colleges, this study indicates problems of the entrepreneurship education in Korea, and discusses the effective methods for improvement on an entrepreneurship education.