통일을 대비한 영동지역 안보관광자원의 역할

심상화,최지연 도립 강원전문대학 2000 道立 江原專門大學 論文集 Vol.3 No.-

Tourism is one of the best effective mean to dissolve the hostility between nations or areas and also to believe each other. The aims of the study is to survey the developed situation and the role of the security resources for tourism, and to suggest the desirable developing direction of the security resources for tourism. The research area was limited within Gangdong Security one, and as one way of the study, the literary research and the field one were conducted together.

냉수 가글링과 젖은 거즈를 이용한 구강간호가 비강수술 환자의 갈증 및 구강상태에 미치는 효과 비교

이인선,심명숙,나은희,강재연,김지혜,황민영,윤계숙,성영희 병원간호사회 2006 임상간호연구 Vol.11 No.2

Purpose: This study researched the comparison of oral care methods between the wet gauze and the water gargling for nasal surgery patients. It executed to find out more effective method to relieve thirst. Method: We divided two groups; the wet gauze and the cold water garaling. We assessed patient's oral cavity state and sebjective oral dryness for three times; firstly before the intervention, secondly 15 minutes after 1st intervention and thirdly 15 minutes afrer 2nd intervention. Result: As the intervention, there was no difference on oral condition subhectvely, but there was a difference on thirsty reduction objectively. As the aral dryness has relieved through both methods. It showed the repeated gargling helps more to relieve oral dryness effectively than the wet gauge. At PACU, post nasal surgery patient's oral dryness was decreased with gauze more than two times, patient's oral dryness was relieved. Whereas the dryness was relieved after applying the cold water gargling for just one time. Conclusion: The water gargling is more effective intervention than the wet gauze. Especially, oral dryness was improved in the section of objetive oral assessment index.

간경변으로 입원한 환자 33례에 대한 분석

최서형,심민,김태수,민지연,최영규,Choi, Seo-Hyoung,Sim, Min,Kim, Tae-Soo,Min, Ji-Yeon,Choi, Young-Gyoo 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.4

Objective : Liver cirrhosis is a disease of the liver in which normal cells are replated by scar tissue. Chronic liver disease and liver cirrhosis are the foutth ranked causes of death in Korea. However, clinical data on liver cirrhosis is not accumulated in oriental medicine. Therefore, clinical characteristics of 33 liver patients admitted to Hana Oriental Hospital from May 2004 to May 2005 were studied. Methods : Clinical characteristics of liver cirrhosis, such sex, age, causes, Child-Pugh class, chief complain, abdomen ultrasonography, disease duration, past history, blood test and urinalysis were reviewed. Results : The results of this study were as follows: 1 The distribution of sex and age in our study is similar to already reported statistics. 2. Hepatitis B and alcohol are the major factors to cause the liver cirrhosis. Diabetes and hypertention contribute more to cause than they have in previous histories. 3. Major symptoms are following: fatigue 87.9%, ascites 84.8%, jaundice 78.8%, leg edema 72.7%, dyspepsia 45.5%. 4. Most liver cirrhosis patients have pancytopenia. Standard Deviation accentuates the big differences between total bilirubin and serum amonia. 5. In urinalysis, Urobilinogen 19 patients (57.6%), bilirubin 12 patients (36.4%), blood 15 patients (45.5%) are positive. 11 cases of 15 in blood positive results scored $3{\sim}4+$. Contusions : In oriental medicine, it will be necessary to research and develop oriental medical therapies for liver disease including liver cirrhosis.

저장 기간에 따른 사과의 품질특성과 항산화 활성 변화

진소연,심기현,이은지,구혜진,김명현,한영실,박정수,김용훈,Jin, So-Yeon,Sim, Ki Hyeon,Lee, Eun Ji,Gu, Hae Jin,Kim, Myung Hyun,Han, Young Sil,Park, Jung Su,Kim, Yong-Hoon 한국식품영양학회 2014 韓國食品營養學會誌 Vol.27 No.6

$20^{\circ}C$에서 15일 동안 저장기간별 사과의 변화를 살펴본 결과는 다음과 같다. 사과의 중량과 수분은 저장기간 경과에 따라 점차적으로 감소하는 결과를 보였으며, 사과의 저장 중 가용성 고형물 함량은 저장 4일차까지 최고치로 증가하였다가 서서히 낮아지는 경향을 나타냈다. 사과의 저장 중 유기산 산도는 저장 5일차에 급격히 감소하다가 완만히 감소하였으며, pH는 저장기간에 따라 완만히 증가하는 경향을 나타내었다. 저장 중 사과 껍질의 색상을 측정한 결과, L값은 저장기간에 따라 서서히 증가하였으며, a값은 저장 3일까지 감소하였고, 저장 5일에 증가되었다가 그 이후 점진적으로 감소하였다. b값은 저장 6일에 최저치를 보인 후 서서히 증가하는 경향을 보였다. 사과의 조직감을 측정한 결과, 저장기간이 증가됨에 따라 사과의 경도는 전반적으로 감소하였다. 저장 기간에 따른 사과의 총 페놀과 총 플라보노이드 함량을 측정한 결과, 총 페놀 함량은 저장 기간이 길어질수록 감소하는 경향이 나타났으며, 저장 3일차에서 저장 4일차에 큰 폭 감소하였다. 총 플라보노이드의 변화 결과, 1일차에 비교적 크게 감소하였고, 실험 7일차에서 8일차 사이에 급격히 감소하였다. 저장 기간에 따른 사과의 DPPH 전자공여능 측정결과, 저장기간이 증가할수록 DPPH 전자공여능은 감소하였으며, Vit. C 함량의 경우 저장 기간이 길어질수록 감소하였는데, 특히 저장 4일차에 비교적 크게 감소하였다. 사과의 관능평가 수행 결과, 저장기간이 경과함에 따라 외관의 좋은 정도는 0일차에 6.75에서 15일차 2.83으로 크게 감소하였으며, 신맛의 좋은 정도는 저장 기간에 따라 유의적인 차이를 보이지 않았으나, 전반적으로 감소하는 경향이었다. 단맛의 좋은 정도와 아삭함의 좋은 정도에서는 0일차에 각 6.25, 5.33으로 가장 높았으며, 15일차에 각 3.92, 2.83으로 유의적으로 감소하였다. 종합적인 기호도에서는 7일차와 8일차 사이에 5.00에서 3.50으로 비교적 큰 폭 감소하였으며, 15일차에 2.00으로 저장 기간에 지남에 따라 유의적으로 감소하였다. 이상의 실험결과, 사과 저장 시 3~4일차에 유의적인 차이를 보였으며, 저장 8일 이후에는 모든 항목에 있어 측정감이 크게 변화하는 경향을 나타내었다. 따라서 $0{\sim}1^{\circ}C$에서 장기 저장한 사과를 $20^{\circ}C$ 전후에서 저장 및 판매할 경우, 최고의 품질을 위해서는 3일 내에 판매할 것을 권장하며, 8일 이내에 재고를 소진할 수 있도록 유통 기간을 조정하는 것이 바람직할 것으로 사료된다. This study was performed in order to compare the changes in Korean apples' qualities and antioxidant activity when stored at room temperature, $20^{\circ}C$, for fifteen days. The results showed that the weight, moisture content, soluble solid content, acidity, and hardness levels decreased as the storage period increased. However, pH and color value L increased as the storage period increased. Total phenol contents, total flavonoids contents, DPPH free radical scavenging activity, and vit. C contents of apples significantly decreased with increased storage period. Sensory parameters, such as appearance, sweetness, sourness, crunchiness, and overall acceptability of apples, also decreased as the storage period increased. Based on these results, if, the apple are being stored around $20^{\circ}C$, then, to have the highest quality, the apples should be sold within three days, We also suggested that it is desirable not to store the apples fore more than eight days.

[PH-0005] Effects of CO₂ supply on growth and antioxidant activity of fennel (Foeniculum vulgare Mill.)

Na Yeon Jo(Na Yeon Jo ),Jun kyung Lee(Jun kyung Lee ),Su Yeon Sim(Su Yeon Sim ),No Eul Hong(No Eul Hong ),Ji Eun Byun(Ji Eun Byun ),Sun Goo Hwang(Sun Goo Hwang ) 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-

Comparing the accuracy (trueness and precision) of models of fixed dental prostheses fabricated by digital and conventional workflows

Sim, Ji-Young,Jang, Yeon,Kim, Woong-Chul,Kim, Hae-Young,Lee, Dong-Hwan,Kim, Ji-Hwan Elsevier 2019 Journal of prosthodontic research Vol.63 No.1

<P><B>Abstract</B></P> <P><B>Purpose</B></P> <P>This study aimed to evaluate and compare the accuracy.</P> <P><B>Methods</B></P> <P>A reference model was prepared with three prepared teeth for three types of restorations: single crown, 3-unit bridge, and inlay. Stone models were fabricated from conventional impressions. Digital impressions of the reference model were created using an intraoral scanner (digital models). Physical models were fabricated using a three-dimensional (3D) printer. Reference, stone, and 3D printed models were subsequently scanned using an industrial optical scanner; files were exported in a stereolithography file format. All datasets were superimposed using 3D analysis software to evaluate the accuracy of the complete arch and trueness of the preparations. One-way and two-way analyses of variance (ANOVA) were performed to compare the accuracy among the three model groups and evaluate the trueness among the three types of preparation.</P> <P><B>Results</B></P> <P>For the complete arch, significant intergroup differences in precision were observed for the three groups (<I>p</I> <.001). However, no significant difference in trueness was found between the stone and digital models (<I>p</I> >.05). 3D printed models had the poorest accuracy.</P> <P>A two-way ANOVA revealed significant differences in trueness among the model groups (<I>p</I> <.001) and types of preparation (<I>p</I> <.001).</P> <P><B>Conclusions</B></P> <P>Digital models had smaller root mean square values of trueness of the complete arch and preparations than stone models. However, the accuracy of the complete arch and trueness of the preparations of 3D printed models were inferior to those of the other groups.</P>

Review Article : Nitric oxide and pulmonary hypertension

Ji Yeon Sim 대한마취과학회 2010 Korean Journal of Anesthesiology Vol.58 No.1

Pulmonary hypertension is a serious complication of a number of lung and heart diseases that is characterized by peripheral vascular structural remodeling and loss of vascular tone. Nitric oxide can modulate vascular injury and interrupt elevation of pulmonary vascular resistance selectively; however, it can also produce cytotoxic oxygen radicals and exert cytotoxic and antiplatelet effects. The balance between the protective and adverse effects of nitric oxide is determined by the relative amount of nitric oxide and reactive radicals. Nitric oxide has been shown to be clinically effective in the treatment of congenital heart disease, mitrial valvular disease combined with pulmonary hypertension and in orthotropic cardiac transplantation patients. Additionally, new therapeutic modalities for the treatment of pulmonary hypertension, phosphodiesterase inhibitors, natriuretic peptides and aqueous nitric oxide are also effective for treatment of elevated pulmonary vascular resistance. (Korean J Anesthesiol 2010; 58: 4~14)

Isolation of Nontuberculous Mycobacteria from a Showerhead in Patient with Nontuberculous Mycobacteria

( Ji Yeon Choi ),( Bo Ra Sim ),( Song Yee Kim ),( Eun Young Kim ),( Sang Hoon Lee ),( Kyung Soo Chung ),( Ji Ye Jung ),( Moo Suk Park ),( Young Sam Kim ),( Young Ae Kang ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.0

Background The environments are the source of exposure to most nontuberculous mycobacteria (NTM) involved in human infection, and it is important to reduce the frequency of exposure from environmental sources for preventing NTM infection. The aim of this study was to examine the NTM inside showerheads in patients with NTM pulmonary disease, because household water has been considered as one of the possible sources of NTM. Methods Samples were taken from 32 showerheads in patients with NTM pulmonary disease recruited through the Pulmonary Outpatient Clinic between October 2018 and October 2019. In order to determine the composition of the showerhead, washing fluids were examined using the multiplex PCR assay and cultured by conventional Methods. Subsequently, suspected microbial isolates in washing fluids and culture were identified using sequencing analysis of 16S rRNA gene. Results The patients consisted of 25 females and 7 males, and their ages were 59 years (range 30 to 72 years). The species of NTM that caused the patient’s pulmonary disease infection were Mycobacterium avium (n=17, 57%), M. intracellulare (n=7, 23%), M. abscessus (n=1, 3%), M. massiiliense (n=1, 3%), and M. fortuitum complex (n=1, 3%). In 17 showerhead samples, we identified potentially pathogenic mycobacteria isolated from the showerhead. However, species identified in the showerhead not matched those of the patient’s strain and few NTM causing the human disease were isolated from the showerhead; M. florentinum, M. phocaicum, M. gordonae, M. mucogenicum, M. gilvum, M. llatzerense, M. peregrinum, M. triplex. Despite a predominance of NTM species, we did not demonstrate the main pathogen associated with disease in the patients studied. Conclusion This report provides evidence that the showerhead may present potential exposure to NTM.

Pain on injection with microemulsion propofol

Sim, Ji-Yeon,Lee, Soo-Han,Park, Do-Yang,Jung, Jin-Ah,Ki, Kyoung-Ho,Lee, Dong-Ho,Noh, Gyu-Jeong Blackwell Publishing Ltd 2009 British Journal of Clinical Pharmacology Vol.67 No.3

<P><B>WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT</B></P><P>• Aqueous free propofol in lipid emulsion elicits pain.</P><P>• No data on the incidence and severity of injection pain for Aquafol™ (Daewon Pharmaceutical Co., Ltd, Seoul, Korea), a lipid-free microemulsion propofol, are available.</P><P>• Two hypotheses involving plasma bradykinin generation have been proposed to explain propofol-induced pain; one implicates aqueous free propofol, the other implicates the lipid solvent.</P><P><B>WHAT THIS STUDY ADDS</B></P><P>• Microemulsion propofol produces more frequent and severe pain on injection, an effect that may be attributable to the high concentration of aqueous free propofol.</P><P>• There was no evidence that plasma bradykinin generation caused propofol-induced pain.</P><P>• In addition, agents known to prevent propofol-induced pain did not decrease aqueous free propofol concentrations.</P><P>AIMS</P><P>To evaluate the incidence and severity of injection pain caused by microemulsion propofol and lipid emulsion propofol in relation to plasma bradykinin generation and aqueous free propofol concentrations.</P><P>METHODS</P><P>Injection pain was evaluated in 147 patients. Aqueous free propofol concentrations in each formulation, and in formulation mixtures containing agents that reduce propofol-induced pain, were measured by high-performance liquid chromatography. Plasma bradykinin concentrations in both formulations and in their components mixed with blood sampled from six volunteers were measured by radioimmunoassays. Injection pain caused by 8% polyethylene glycol 660 hydroxystearate (PEG660 HS) was evaluated in another 10 volunteers.</P><P>RESULTS</P><P>The incidence of injection pain [visual analogue scale (VAS) >30 mm] caused by microemulsion and lipid emulsion propofol was 69.7 and 42.3% (<I>P</I> < 0.001), respectively. The median VAS scores for microemulsion and lipid emulsion propofol were 59 and 24 mm, respectively (95% confidence interval for the difference 12.5, 40.0). The aqueous free propofol concentration of microemulsion propofol was seven times higher than that of lipid emulsion propofol. Agents that reduce injection pain did not affect aqueous free propofol concentrations. Microemulsion propofol and 8% PEG660 HS enhanced plasma bradykinin generation, whereas lipid emulsion propofol and lipid solvent did not. PEG660 HS did not cause injection pain.</P><P>CONCLUSIONS</P><P>Higher aqueous free propofol concentrations of microemulsion propofol produce more frequent and severe pain. The plasma kallikrein–kinin system may not be involved, and the agents that reduce injection pain may not act by decreasing aqueous free propofol concentrations.</P>

[P4-211103] 소셜미디어의 빅데이터를 활용한 정원문화에 대한 대중의 인식 동향 분석

심지연(Ji Yeon Sim),이현정(Hyunjung Lee),진민령(Min Ryeong Jin),최유림(Yu Rim Choi),이경미(Kyungmi Lee),진혜영(Hye-Yeong Jin),배준규(Jun-kyu Bae) 인간식물환경학회 2021 인간식물환경학회 학술대회 Vol.2021 No.추계