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      • 다발성 간종괴의 형태로 나타난 특발성 과호산구 증후군 치험1예

        최승오,연규민,이승민,김순제,왕준호,박형석,이재동,진춘조,이창훈,신현준,김정은 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

        Hypereosinophilic syndrome is characterized by persistent blood eosinophilia of 1,500/ul or more in the absence of known causes and multiorgan dysfunction by eosinophil-related tissue damage. In Korea, some cases of hypereosinophilic syndrome with hepatic involvement have been described with prolonged benign clinical courses. Most of them were diffuse or multifocal lesions in imaging studies, and a few case presenting as a single mass has been described. Here we report a case of hypereosinophilic syndrome with hepatic involvement in a 65-year-old man who presented with multifocal mass lesions. By abdominal US and CT scan, multiple, ill-defined nodules were detected in throughout the liver. Liver biopsy revealed severe eosinophilic hepatitis, suggestive of hypereosinophilic syndrome. Hepatic mass lesions improved after steroid administration for several weeks.

      • KCI등재
      • KCI등재후보

        비중격 천공이 없는 크롬 노출 근로자에서의 후각장해에 관한 연구

        최재욱,이성희,최연국,이은일,김해준 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

        Objectives : The chrome-induced olfactory alterations is caused by inhalation of chromic acid, a highly corrossive and toxic materials. And nasal septum perforation (NSP) has been suspected with possible causative factor of olfactory alterations. To our knowledge, there has been no report of the detailed findings of the olfactory alterations in chrome exposed subjects without nasal septum perforation (NSP). So we present the results of olfactory function test measured by T&T olfactometer and olfactometer perception test among chromium exposed workers without NSP. Methods : We performed this study in 25 study subjects and 25 control subjects matched with age, alcohol and smoking. All of subjects are man. We performed olfactory function test measured by T&T olfactometer and olfactometer perception test. Results : 1) The age distribution of the subjects involved in this study was from 20 to 54 years old (average 33.3 years old) and the mean duration exposed to chromium was from 64.9 months. 2) The olfactory function was checked by detection and recognition thresholds in five odorants. The detection thresholds of exposed group dealing with chromium were significantly increased in A and B ordorants than nonexposed group. The recognition thresholds of exposed group were significantly increased in D ordorants than nonexposed group. 3) The mean threshold of olfactometer perception test of exposed group were more increased than nonexposed group. But thresholds difference did not show statistical significance. 4) The detection thresholds of A and D ordorants, recognition threshold of C ordorants and thresholds of olfactometer perception test were increased in the relation with duration of chrome exposure. Conclusions : There has been no remarkable alterations in olfactory sense (T&T olfactometer and Olfactometer Perception Test) in subjects without nasal septum perforation (NSP) exposed to chromic acid.

      • KCI등재

        칫솔질 교육의 치면 세균막 억제 효과

        유은규,손미연,최성철,김광철,박용덕,박재홍 大韓小兒齒科學會 2012 大韓小兒齒科學會誌 Vol.39 No.1

        To maintain good oral hygiene, plaque control is essential and the most common and effective method is appropriate brushing. However accurate brushing is so difficult for children that the importance of brush is getting higher. We investigated the effect of tooth brushing instruction in plaque control for 40 children who came to Kyunghee university dental hospital, department of pediatric dentistry. We examined basic information by self-assessment, evaluated plaque index, tooth & tongue cleanness, malodor index for 4 times and compared values before and after tooth brushing instruction. Plaque index decreased(p<0.01) and tooth & tongue cleanness increased(p<0.01). There were no significant differences in mal-odor index. In conclusion, tooth brushing instruction is effective in removing dental plaque and its beneficial role is highly expected in establishing children’s good oral hygiene. 좋은 구강 위생 환경을 유지하기 위하여 치태 조절은 필수적이며, 가장 보편적이고 효과적인 방법은 올바른 칫솔질이다. 그러나 아동들은 올바른 칫솔질을 시행하기 어려워 칫솔질 교육의 중요성도 높아지고 있어, 경희대학교 치과대학 소아치과에 내원한 아동 40명을 대상으로 칫솔질 교육의 치태 조절의 효과를 조사하였다. 설문조사를 통해 기본 정보를 조사하고 치면 세균막 지수와 치아 및 혀 세정도, 구취 관리도를 측정하는 조사를 총 4회에 걸쳐 시행하여 칫솔질 교육 전과 후의 차이를 비교하였다. 치면 세균막 지수는 감소하였고(p<0.01), 치아 및 혀 세정도는 증가하였다(p<0.01). 구취관리도는 상관성을 보이지 않았 다(p>0.01). 이러한 결과 칫솔질 교육은 구강 내 치면 세균막 제거에 뛰어난 효과를 보여, 아동들의 좋은 구강 위생 환경의 확립에 도움 을 줄 것으로 기대된다.

      • 밀레니엄 광고세대의 커리어 행로(carrer path)에 관한 문헌연구

        최은하,김재영 남서울대학교 2004 남서울대학교 논문집 Vol.10 No.1

        This paper aims at study of the career path that is the most important decision factor of millennium generation's lifestyle. Because millennium generation will be new market indicator, of 21 century. For this study, this paper is based on generation Gap that is dealt with all social science. Where Traditionalists seek to build lifetime careers, Boomers to build stellar careers, and Xers to build portable careers, the career path ClashPoint for Millennials will be around parallel careers. Millennials' programmed live have made them true multitaskers. Millennials are already quite capable of learning several jobs simultaneously and performing them admirably. Millennials are throwing out the old model that you're either a waitress, a hostess, or running the register. In a tight labor market, making sure scarce Millennials can cover more than one position is a smart strategy. In a contracting economy, it's cost-effective to put Millennials' multitasking abilities to use rather than hire more employees. Plus, cross-training is a great retention strategy, which reduces the expense of turnover. Futurists predict that Millennials will experience as many as ten career changes in their lifetimes. That's career changes, not job changes-meaning they will recycle their skills and talents and personal preferences into new application again and again and again. Throughout their careers, this generation will be ready, willing, and able to adapt to an organization's evolving structure.

      • 저널리스틱 일러스트레이션의 발전방향에 관한 연구 : 시대사적 관점에서 from a historical viewpoint

        최재은 명지대학교 예체능연구소 2001 藝體能論集 Vol.12 No.-

        The purpose of this study is to suggest the multi-cultural role and importance of journalistic illustration, by defining the essential meaning of journalistic illustration and by studying the process of its development. Journalistic illustration, which had been developed from the West at the beginning of the eighteenth century, is recently established in not only scientific area but also more generalized social area thanks to the development of mass media and computer. However, the journalistic illustration of Korea with a relatively short history has been declined gradually, because its growth surroundings are poor and organizations for it are small. To recover such a cultural inferiority, illustrators shall have a sense of mission for journalist illustration, and the members of our society shall change their thinking on it. In addition, systematic support and interest for journalistic illustration are needed.

      • ROSAE MULTIFLORAE RADIX의 藥理作用에 關한 硏究

        殷載淳,韓宗鉉,崔動晟 又石大學校 1989 論文集 Vol.11 No.-

        In an attempt to investigate the effect of ROSAE MULTIFLORAE RADIX(RME) on the diabetes in rats induced by alloxan(80 ㎎/㎏) or streptozotocin(40 ㎎/㎏) and the contractile force of isolated rabbit ileum, RME was administered per oral daily and the level of blood glucose, serum triglyceride and serum total cholesterol were measured by spectrophotometer and the contractile force of intestine was measured by physiograph. The following resuits were obtained: 1) RME did not change the level of blood glucose and serum total cholesterol, but decrease the serum triglyceirde on the 5th day in normal rats. 2) The level of blood glucose in diabetic rats induced by the alloxan was decreased on the 5th and 7th day of experiment (RME 100㎎/㎏), induced by streptozotocin was decreased on the 7th day of experiment (RME 10 ㎎/㎏) and 5th and 7th day of experiment (RME 100 ㎎/㎏). 3) The level of serum triglyceride in dibetic rats induced by the alloxan was decreased 7th day (RME 100 ㎎/㎏) and induced by streptozotocin was decreased 7th day (RME 10 ㎎/㎏) and 3th, 5th and 7th day (RME 100 ㎎/㎏) of experiment. 4) The level of serum total cholesterol in diabetic rats induced by the alloxan and streptozotocin was not changed by RME. 5) The contractile response of isolated rabbit ileum by RME was not affected by cyproheptadine, but inhibited by atropine and verapamil.

      • 體育特技者의 肺機能과 運動後 恢復期의 血液가스의 變化

        崔圭澤,朴載植,黃樹寬,朱永恩 慶北大學校 1985 論文集 Vol.39 No.-

        The pulmonary function and changes of blood gas tensions and pH in the athletes have been reported but are fragmentary as to require more complete studies including all the pulmonary parameters and blood gas tensions especially at the early part of 20 years of age. This study was aimed to elucidate the pulmonary function at the rest and the changes of venous blood gas tension and pH after the exercise in the athletes of physical education students. The subjects chosen for this study were 15 athletes of physical education students (special group) of 21-25 years of age. The athletes had at least four years of exercise careers, and were compared with 12 non-athletes of physical education students (general group) who had not been subjected to any form of rigorous training program. All the subject were directed to perform running on the treadmill for three minutes under the condition of 15% grade and 5 MPH. The venous blood samples were taken at the rest as well as at 0, 5, 10 and 20 minutes after the exercise to check the changes of Pco_2, Po_2 and pH during the recovery period. The venous blood Pco_2, Po_2 and pH were determined using the Model 175 Automatic Blood Gas Analyzer by Corning Co., and the pulmonary function using the computerized spirometer. The results obtained were compared with the general group and summarized as follows: The special group exhibited higher values of the pulmonary function except FVC compared with the general group, and particularly FEV_0·5% and FEV_1% were significantly different. The venous Po_2 was decreased immediately after the exercise, but increased during the recovery period. The special group generally showed higher oxygen partial pressure than the general group. The venous Pco_2 in contrast to the oxygen increased immediately after the exercise, but decreased during the recovery period. The special group showed lower carbon dioxide partial pressure. Blood pH was significantly decreased from the resting value after the exercise and returned to the resting value at 20 minutes. In the special group, however, the change of pH was less than in the general group.

      • 초등학생들의 열과 온도에 대한 대안개념 조사

        최행숙,김은경,백성혜,이길재,정완호 한국교원대학교 과학교육연구소 2001 청람과학교육연구논총 Vol.11 No.1

        In this study, the contents of elementary school science textbooks related to 'heat and temperature' are analyzed and alternative conceptions of "heat and temperature" among students enrolled in grades 4, 5 and 6 are investigated. 259 students were selected from a elementary school located in urban area. The relationships between students' alternative conceptions and the content of elementary science textbooks are also examined. Students' conceptions are analyzed from their answers to a paper-and-pencil test. The typical alternative conception of "heat and temperature" held by students was follows. They think that "heat" is a material and "temperature" is value of heat amount. They can't distinguish between "heat" and "temperature". Their explanation of "heat and temperature" is focused on hot or cool sensation and other observable characteristics of a material. A textbook analysis indicated that contents on "heat and temperature" were organized without the viewpoint of particle motion theory. This may be one of the causes of students' alternative conceptions.

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