여름철 계룡산국립공원 탐방로의 열쾌적성 및 어메니티 관리 연구

안시옥(Siok An),송도윤(Doyun Song),정다워(Dawou Joung),박범진(Bum-Jin Park),심규원(Kyu-Won Sim),박준효(Jun-Hyo Park) 국립공원연구원 2022 국립공원연구지 Vol.13 No.2

본 연구는 산악환경의 기상 특징과 계룡산국립공원 탐방로의 열쾌적성을 파악하고 열쾌적성이 높은 활동 시간 정보, 활동 공간 정보, 활동량 정보를 제공하기 위해 시행되었다. 탐방로의 열쾌적성 분석을 위해 여름철 도심 기온, 국립공원 방재기상관측장비(AWS, Automatic Weather System), 탐방로인 숲길의 평균 기온을 비교하였다. 또한, 계룡산 국립공원의 주요 탐방로 4개 구간의 미기후 요소와 수관울폐도 측정을 위해 총 240개 지점을 조사 후 열쾌적성을 파악 하였다. 도심과 국립공원AWS, 탐방로의 평균 기온을 비교하였을 때, 도심, 갑사AWS, 동학사AWS, 갑사 탐방로, 동학사 탐방로 순으로 평균 기온이 높게 나타났다. 이 결과, 탐방객이 직접 체감하는 탐방로의 열쾌적성을 고려해야 함을 의미한다. 주요 탐방로 4개 구간 조사 결과, 평균 수관울폐도는 동학사~남매탑 구간, 동학사~관음봉 구간, 갑사~연천봉 구간, 갑사~금잔디고개 구간 순으로 높았다. PMV(예상평균온열감)는 활동량이 2.8MET 일 때, 갑사~금잔디고개 구간, 갑사~연천봉 구간, 동학사~남매탑, 동학사~관음봉구간 순으로 높았다. 조사를 통하여, 열쾌적성이 높은 시간 정보, 공간 정보, 활동량 정보를 제시할 수 있었다. 탐방로의 열쾌적성 특성을 파악하여, 탐방로의 어메니티를 높일 수 있는 숲길 관리 방안의 기초를 마련하고자 한다. This study was conducted to understand the weather characteristics of the mountain environment and the thermal comfort of Gyeryongsan National Park trail and to provide information on activity time, activity space, and activity amount. For the analysis of the thermal comfort of the trail, the temperature of the city center in summer, the average temperature of the National Park Disaster Prevention Weather System (AWS), and the trail. Also, Microclimate elements and canopy closure were also measured in four major trails in Gyeryongsan National Park. After investigating a total of 240 points, thermal comfort was identified. When comparing the average temperature of the city center, National Park AWS, and trail, the average temperature was higher in the order of the city center, Gabsa AWS, Donghaksa AWS, Gabsa Trail, and Donghaksa Trail. As a result, it means that the thermal pleasure experienced by visitors should be considered. According to a survey of four major trails, the average canopy closure is Donghaksa~nammaetop route was high in the order of Donghaksa~Gwaneumbong route, Gabsa~Yeoncheonbong route and Gabsa~Geumjandigogae route. When PMV(Predicted Mean Vote) is 2.8MET, The PMV was highter in the order of Gabsa~Geumjandigogae route, Gabsa~ Yeoncheonbong route, Donghaksa~nammaetop route, Donghaksa~Gwaneumbong route. Through the survey, time information, spatial information, and activity information with high thermal comfort could be presented. By grasping the thermal comfort characteristics of the trail, we intend to lay the foundation for forest trail management measures that can increase the amenity of the trail.

마늘 잼의 저장과정 중 성상변화

박혜민,곽효순,김소희,문미아,오만진 충남대학교 농업과학연구소 2008 농업과학연구 Vol.35 No.2

In order to make a functional jam containing garlic, sugar, acid and pectin were mixed with garlic and concentrated by heating the mixture under atmosphere or vacuum conditions. And changes of some physico-chemical properties of the garlic jam(i.e., color, textural properties, vitamin C) were investigated during storage at 30℃. It was found that lightness(L) was higher in sample of vacuum concentration than that in atmosphere concentration and redness(a) and yellowness(b) were higher in sample of atmosphere concentration. During the storage lightness was found to decrease for all samples with more drastic decrease in sample of atmosphere concentration where browning was more severely observed after 8 weeks of storage. In terms of textural properties, hardness, chewiness and gumminess were higher in sample of atmosphere concentration than that in vacuum concentration. And springiness and cohesiveness were higher in sample of vacuum concentration. Although sensory score for garlic jam found to be lower than that for the existing strawberry jam, the present garlic jam might have high marketability if considering its physiological value. 마늘을 이용한 기능성 잼을 제조하기 위하여 마늘에 당, 산, 펙틴을 첨가하고 평압과 감압에서 농축하여 마늘잼을 제조한 후 색도, 조직특성을 조사하고 30℃에서 저장하면서 색도, 조직의 변화, 비타민 C의 변화를 측정한 결과는 다음과 같다. 원료마늘의 일반성분은 수분 57.2%, 탄수화물 23.6%, 조단백 1.9%, 조지방 0.75%, 회분0.93%이었고 비타민 C는 8.4 mg/l00g이었다. 명도는 진공농축한 것이 평압농축한 것보다 높았고 적색도와 황색도는 평압의 것이 높았다. 저장기간에 따라 명도는 모두 감소하였으나 평압에서 농축한 것이 감압보다 크게 감소하였으며 갈변화가 저장 8주에는 심하게 나타났다. 마늘잼의 조직특성은 hardness, chewiness, gumminess는 평압농축이 감압농축에 비하여 높았고 springiness, cohesiveness는 평압농축이 낮았다. 마늘잼의 기호성은 딸기잼에 비하여 떨어지지만 기능성을 감안할 때 시장성이 매우 높을 것으로 판단한다.

EPx 자동생화학분석기와 컴퓨터간의 양방향 통신 시스템 구축

박기현,전효진 啓明大學校 醫科大學 1995 계명의대학술지 Vol.14 No.4

It has been understand that a laboratory information system(LIS) plays an important role in a hospital information system(HIS). However, few HIS has been equipped with a fully automated LIS. This is partly because, in order to achieve a fully automated LIS, there are many testing equipment has its own communication protocol. In this paper, a bi-directional communication system between an ABBOTT SPECTRUM EPx auto-chemical analyzer and a PC is constructed. With the communication system, it is possible that a PC controls an EPx's operations and that the PC receives test results form the EPx automatically. RS-232C serial ports are used in order to make bi-directional communication possible between them

위암과 식도암이 병발된 다발성 원발성 악성종양 1예

박사영,이나영,이효진,이선영,최진혁,이순남,심강섭,성순희,한운섭 梨花女子大學校 醫科大學 醫科學硏究所 1996 EMJ (Ewha medical journal) Vol.19 No.3

Multiple primary cancer means that more that two cancers occur independently in an individual. Recently, the incidence of multiple primary cancer has increased with lengthened survival, of cancer patients, development of new diagnostic technique and increased clinical evaluation. We report a patient who had adenocarcinoma of stomach combined with squamous cell carcinoma of esophagus simultaneously.

Inhibitory Effect of Clavicepitaceae on Serotonin Release out of Human Platelets and Human Platelet Aggregation

박화진,--,--,--,--,--,-- THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 2004 Journal of biomedical laboratory sciences Vol.10 No.1

We have investigated the effects of hypha-water extracts (HWE), fruit body-water extracts (FWE) and cordycepin from Cordyceps militaris on serotonin release out of human platelets and human platelet aggregation. HWE and FWE inhibited the release of [^(3)H]-serotonin from human platelet stimulated by thrombin (2 U/ml) or collagen (20 ㎍/ml) in a dose-dependent manner. Furthermore, cordycepin, a major component of Cordyceps militaris, inhibited the human platelet aggregation induced by collagen (10 ㎍/ml) in a dose-dependent manner. These results suggest that cordycepin containing in HWE and FWE may inhibit the serotonin release by suppressing the collagen-induced human platelet aggregation. Accordingly, our data demonstrate that HWE and FWE containing much cordycepin might have antithrombotic and antimigrainous functions.

운전행동 결정요인분석을 통한 운전행동 재설계에 관한 연구

박미소,윤효진 경기대학교 산업기술종합연구소 2006 산업기술종합연구소 논문집 Vol.31 No.-

일반적으로 교통사고의 원인을 자동차, 운전자, 도로교통환경등의 세 가지 삼각구도로 규명하지만, 교통사고의 직접적인 원인은 교통행동에 의해 결정되어진다고 할 수 있다. 따라서 본 논문에서는 사고원인의 물리적 요소 외에도 인간행동을 결정짓는 요인들을 통해 행동결함들을 분석하여 결함에 대한 대책을 세울 수 있는 방법을 제시하고자 하는 것이다. 결함요인들에 대한 분석을 통해서 특히, 지각·운동요인과 성격요인의 요소들을 통해 결함의 순위를 결정해 보고자 한다. 그리고 이러한 결함을 어떻게 대처해야 할지 운전 재설계의 원칙을 제고해 보는데 그 의의를 두고 있다. 교통과 관련된 일을 하고 있는 일반인들보다는 다소 많은 지식, 정보 그리고 경험을 가지고 있는 전문가들을 대상으로 여러 가지 상세한 설문을 통해서 결함요소와 교통사고, 결함요소간의 상관관계를 분석하여 각 요소에 대한 가중치를 결정하고 다시 이것을 주관성의 일정 부분 배제를 위해 일반화 시켜 그 가중치에 따른 결함 점수의 합계를 구해 어떤 결함이 얼마나 많은 문제점이 있는지 분석하였다. 그리고 최종 결함 점수가 가장 높은 결함을 선정하여 제시된 재설계 원칙에 따라서 운전 행동결함을 수정할 수 있는 정보를 얻고 스스로의 운전 단점을 보완하는데 필요한 자료의 가이드라인으로 활용할 수 있다.

셀레콕시브 및 그 합성유도체들의 항암활성 스크리닝

박정란,강진형,구효정,노지영,류형철,박상욱,고동현,조일환,이주영,황다니엘,김인경 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.2

Selective COX (cyclooxygenase)-2 inhibitors including celecoxib have been shown to induce apoptosis and cell cycle changes in various tumor cells. New inhibitors are recently being developed as chemomodulating agents. We evaluated celecoxib and screened 150 synthetic compounds for anti-proliferative activities in vitro. Effects of celecoxib on COX activity, cell growth, cell cycle distribution, and apoptosis induction were determined in A549 COX-2 overexpressing human non-small cell lung cancer (NSCLC) cells. The COX inhibition of celecoxib increased with concentration up to 82% at 1μM after 24 hr exposure. Forty μM and 50μM of celecoxib induce G_1 arrest, and TUNEL-positive apoptotic cells, respectively. Among 150 compounds, several compounds were selected for having greater COX-2 inhibitory activity and higher selectivity than celecoxib with growth inhibitory activity. Celecoxib showed concentration-dependent COX inhibitory activity, and ability to induce cell cycle arrest and apoptosis in human NSCLC cells in vitro. Among synthetic analogues screened, several compounds showed promising in vitro activity as COX-2 inhibitory anticancer agents, which warrant further evaluation in vitro and in vivo.

Inhibitory Effect of Cordycepin on Human Platelet Aggregation

박화진,--,--,--,--,--,-- THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 2004 Journal of biomedical laboratory sciences Vol.10 No.1

Cordycepin separated from Cordyceps militaris is a major physiologic active component in Cordyceps militaris. The platelet aggregation is stimulated by Ca^(2+), which is either mobilized from intracellular endoplasmic reticulum or transported from extracellular space. cGMP antagonizes the actions of Ca^(2+). Based on these facts, we have investigated the effects of cordycepin on the mobilization of Ca^(2+) and the production of cGMP on collagen (10 ㎍/ml)-induced human platelet aggregation. Cordycepin potently stimulated the human platelet aggregation induced by collagen (10 ㎍/ml) in a dose-dependent manner. Cordycepin (500 μM) inhibited also the collagen-induced human platelet aggregation in the presence both 1 mM and 2 mM of CaCl_(2). These are in accord with the results that cordycepin inhibited the Ca^(2+)-influx on collagen-induced human platelet aggregation. These results suggest that cordycepin decrease the intracellular Ca^(2+) concentration to inhibit collagen-induced human platelet aggregation. Besides, cordycepin increased the level of cGMP on collagen-induced human platelet aggregation. This result is related with the decrease of intracellular Ca^(2+) concentration, because cGMP inhibits the mobilization of Ca^(2+). In addition, cordycepin inhibited the human platelet aggregation induced by LY-83583, inhibitor of guanylate cyclase. This result suggested that cordycepin inhibit the platelet aggregation by stimulating the activity of guanylate cyclase. In conclusion, we demonstrated that cordycepin might have the antiplatelet function by inhibiting Ca^(2+)-mobilization via the stimulation of the production of cGMP.

미세혈관 협심증 환자의 임상상 및 지표에 관한 연구

박상호,온영근,김현정,이태훈,길효욱,김현건,박수진,송해정,한대희,방덕원,신원용,이내희,김성구,권영주 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Background : Microvascular angina or syndrom X is heterogenous and encompasses different pathogenetic entities. Several studies suggest that microvascular angina have good prognosis and occurs predominantly in postmenopausal women. Lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and fibrinogen are the independent risk factor of acute coronary syndrome and are the chief underlying cause of atherosclerosis. We investigated clinical characteristics and markers in patients with microvascular angina. Methods : We studies 23 patients diagnosed with microvascular angina and 16 control group with negative treadmill exercise test and no significant coronary angiogram. We investigated clinical characteristics in patients group and evaluated symptom during a follow-up period of 4.2± 2.5 month. Exercise time in treadmill exercise test was compared between patients and control group. We assessed the level of markers, such as lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and ESR in two groups. Results : There is no difference in age between two groups. Patients group had a tendency to increase in female, hypertension, DM, and smoking history, but there was no statistical significance difference. Exercise duration time was significantly decreased in patients with microvascular angina (p<0,05). Serum lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholestrol, Triglyceride, ESR, Fibrinogen and Homocystein value were no significant difference between microvascular angina and control group. Only CRP was significantly high in patients with microvascular angina (p<0.05). Conclusion : There was no statistical significance difference in age, sex, hypertension, DM and smoking history between two groups but patients group had a tendency to increase the prevalence in hypertension, DM and smoking history, female. Also, Symptom improvement and disappearance in follow-up was presented in 11 patients of 19(57.9%). Exercise tolerance was worse in patients group than control group. CRP value was significantly higher in patients group than control group. There was no statistical significance difference in lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, ESR and Fibrinogen between two groups.

이온 펌프의 제작과 특성에 관한 연구

박종윤,이순보,부진효,신익조 성균관대학교 기초과학연구소 1990 論文集 Vol.41 No.1

By using theoretical model suggested by H. Hartwig et al., performance of sputter ion pump (SIP) was calculated and a SIP was constructed. Measurement of pumping speed of the SIP has been performed with the differential pumping method. The pumping speed for N_2 gas is 48 l/s, and for Ar gas is 20 l/s. These results agree with the theoreticaly expected values.