Uterine alveolar rhabdomyosarcoma in an elderly patient manifesting extremely poor prognosis; a rare subtype of rhabdomyosarcoma

( Haewon Choi ),( Hyunji Lee ),( Hee Sun Kim ),( Jung Yeol Han ),( Kyoung-chul Chun ) 대한산부인과학회 2021 Obstetrics & Gynecology Science Vol.64 No.2

Alveolar rhabdomyosarcoma (ARMS) arising in the corpus uteri is an extremely rare condition with exceptionally rapid progression and poor prognosis. Furthermore, ARMS is primarily diagnosed in the pediatric population. Due to rarity of the disease, there are no standard treatment guidelines. A 90-year-old woman was presented with a huge pelvic mass causing dyspnea and abdominal distension. The patient underwent debulking surgery and was diagnosed with uterine ARMS by fresh specimen biopsy. Despite intensive postoperative care, the patient died on the eighth postoperative day. Here, we report a case of uterine ARMS that will add to our understanding of this exceptionally rare type of tumor.

Clinical Characteristics of Gynecologic Problems During Childhood in the Korean Population

Choi Haewon,Kim Sung Eun,Lee Nae Hyun,Lee Dong-Yun,Choi DooSeok 대한의학회 2023 Journal of Korean medical science Vol.38 No.37

Background: This study analyzed common gynecologic problems among Korean patients younger than ten years. Methods: We performed a retrospective analysis of medical records of patients younger than ten years who visited the Pediatric and Adolescent Gynecology Clinic at Samsung Medical Center between 1995 and 2020. Results: Among the 6,605 patients who visited the Pediatric and Adolescent Gynecology Clinic, data from 642 patients younger than ten years were analyzed in this study. The most common chief complaint was genital anomalies, followed by increased vaginal discharge and abnormal findings on clinical examinations. The most common disease entity was agglutination of the labia minora, which was commonly discovered incidentally during routine screenings. Vulvovaginitis, the second most common disease, was identified by symptoms of vaginal discharge, pruritus, and vaginal spotting. Neoplasm, issues with vaginal bleeding, and “other causes” were additional categories of gynecologic problems. 245 patients (38.2%) were referred from primary care sources, 175 patients (27.4%) sought care directly at the clinic, 169 patients (26.3%) were referrals from the institution’s pediatric department, and the remainder were referrals from other departments. Conclusion: This study provides information about the gynecologic problems most frequently encountered in pediatric patients. The study provides helpful insight for primary care physicians into the proper management and timing of referrals for these gynecologic problems of pediatric patients.

Uterine alveolar rhabdomyosarcoma in an elderly patient manifesting extremely poor prognosis; a rare subtype of rhabdomyosarcoma

( Haewon Choi ),( Hyunji Lee ),( Hee Sun Kim ),( Jung Yeol Han ),( Kyoung-chul Chun ) 대한산부인과학회 2021 Obstetrics & Gynecology Science Vol.64 No.3

Rates and subsequent clinical course of fetal congenital anomalies detected by prenatal targeted ultrasonography of 137 cases over 5 years in a single institute: a retrospective observational study

( Haewon Choi ),( Hyo-shin Kim ),( Joon Sakong ) 영남대학교 의과대학 2023 Yeungnam University Journal of Medicine Vol.40 No.3

Background: With the establishment of international guidelines and changes in insurance policies in Korea, the role of targeted ultrasonography has increased. This study aimed to identify the rates and clinical course of anomalies detected using prenatal targeted ultrasonography. Methods: This study was a retrospective analysis of all pregnancies with targeted ultrasonography performed in a single secondary medical center over 5 years. Results: Fetal anomalies were detected by targeted ultrasonography in 137 of the 8,147 cases (1.7%). The rates of anomalies were significantly higher in female fetuses (2.0% vs. 1.3%). In cases of female fetuses, the rate of anomalies was significantly higher in the advanced maternal age group (2.4% vs. 1.2%). In cases of male fetuses, the rate of anomalies was significantly higher in nulliparous (2.4% vs. 1.5%) and twin (5.7% vs. 1.9%) pregnancies. Pulmonary anomalies were significantly more common in the multiparity group (17.6% vs. 5.8%). Among the 137 cases, 17.5% terminated the pregnancy, 16.8% were diagnosed as normal after birth, and 42.3% were diagnosed with anomalies after birth or required follow-up. Conclusion: Through the first study on the rates and clinical course of anomalies detected by targeted ultrasonography at a single secondary center in Korea, we found that artificial abortions were performed at a high rate, even for relatively mild anomalies or anomalies with good prognosis. We suggest the necessity of a nationwide study to establish clinical guidelines based on actual incidences or prognoses.

Exact Matching Using the Suffix Tree on Disk

Haewon Choi,Kyungjun Kim 대한전자공학회 2005 ITC-CSCC :International Technical Conference on Ci Vol.2005 No.2

Rates and subsequent clinical course of fetal congenital anomalies detected by prenatal targeted ultrasonography of 137 cases over 5 years in a single institute: a retrospective observational study

( Haewon Choi ),( Hyo-shin Kim ),( Joon Sakong ) 영남대학교 의과대학 2023 Yeungnam University Journal of Medicine Vol.40 No.4

Background: With the establishment of international guidelines and changes in insurance policies in Korea, the role of targeted ultrasonography has increased. This study aimed to identify the rates and clinical course of anomalies detected using prenatal targeted ultrasonography. Methods: This study was a retrospective analysis of all pregnancies with targeted ultrasonography performed in a single secondary medical center over 5 years. Results: Fetal anomalies were detected by targeted ultrasonography in 137 of the 8,147 cases (1.7%). The rates of anomalies were significantly higher in female fetuses (2.0% vs. 1.3%). In cases of female fetuses, the rate of anomalies was significantly higher in the advanced maternal age group (2.4% vs. 1.2%). In cases of male fetuses, the rate of anomalies was significantly higher in nulliparous (2.4% vs. 1.5%) and twin (5.7% vs. 1.9%) pregnancies. Pulmonary anomalies were significantly more common in the multiparity group (17.6% vs. 5.8%). Among the 137 cases, 17.5% terminated the pregnancy, 16.8% were diagnosed as normal after birth, and 42.3% were diagnosed with anomalies after birth or required follow-up. Conclusion: Through the first study on the rates and clinical course of anomalies detected by targeted ultrasonography at a single secondary center in Korea, we found that artificial abortions were performed at a high rate, even for relatively mild anomalies or anomalies with good prognosis. We suggest the necessity of a nationwide study to establish clinical guidelines based on actual incidences or prognoses.

The Role of Major Donors in Health Aid to the Democratic People's Republic of Korea

Lee, Haewon,Ahn, Deborah Y.,Choi, Soyoung,Kim, Youngchan,Choi, Hyunju,Park, Sang Min The Korean Society for Preventive Medicine 2013 Journal of Preventive Medicine and Public Health Vol.46 No.3

We investigated the major trends in health aid financing in the Democratic People's Republic of Korea (DPRK) by identifying the primary donor organizations and examining several data sources to track overall health aid trends. We collected gross disbursements from bilateral donor countries and international organizations toward the DPRK according to specific health sectors by using the Organization for Economic Cooperation and Development creditor reporting system database and the United Nations Office for the Coordination of Humanitarian Affairs financial tracking service database. We analyzed sources of health aid to the DPRK from the Republic of Korea (ROK) using the official records from the ROK's Ministry of Unification. We identified the ROK, United Nations Children's Fund (UNICEF), World Health Organization (WHO), United Nations Population Fund (UNFPA), and The Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM) as the major donor entities not only according to their level of health aid expenditures but also their growing roles within the health sector of the DPRK. We found that health aid from the ROK is comprised of funding from the Inter-Korean Cooperation Fund, private organizations, local governments, and South Korean branches of international organizations such as WHO and UNICEF. We also distinguished medical equipment aid from developmental aid to show that the majority of health aid from the ROK was developmental aid. This study highlights the valuable role of the ROK in the flow of health aid to the DPRK, especially in light of the DPRK's precarious international status. Although global health aid from many international organizations has decreased, organizations such as GFATM and UNFPA continue to maintain their focus on reproductive health and infectious diseases.

디지털 텔레비전 환경에서의 문맥인지 캐슁 정책

최지혁(Jihyuk Choi),이해원(Haewon Lee),김수연(Sooyeon Kim),최양희(Yanghee Choi) 한국정보과학회 1999 한국정보과학회 학술발표논문집 Vol.26 No.2Ⅲ

컴퓨터통신 분야 및 개인이동통신 분야 등에서 먼저 도입된 멀티미디어 데이터의 사용이 큰 호응을 얻으면서, 최근 디지털 텔레비전 환경에서 멀티미디어 데이터 방송서비스를 시행하려는 노력들이 이루어지고 있다. 이는 다수의 사용자를 겨냥한 방송서비스로 데이터가 개별 사용자의 요구에 의해서가 아닌 정해진 방송 순서에 의해 제공된다. 따라서 사용자들은 원하는 정보를 수신 할 때까지 대기하게된다. 이러한 응답시간 (response time)을 감소시키기 위해서, 문맥인지 캐슁(context-aware caching) 정책과 캐쉬 점유 우선순위 결정에 핵심이 되는 두 노드사이의 거리 산출을 위한 방법을 제안한다. 또한 선입산출 (first-in-first-out) 정책과의 비교 모의실험(simulation)을 통해, 제안한 문맥인지 캐슁 정책이 응답시간 감소 효과가 좋음을 확인하고, 이를 분석한다.

임플란트 산업의 수익인식에 대한 사례연구

최성호 ( Sungho Choi ),문해원 ( Haewon Moon ),최관 ( Kwan Choi ) 한국회계학회 2018 회계저널 Vol.27 No.4

치과용 임플란트 산업에 종사하는 기업들은 제품판매에 관한 유사한 본질의 거래를 서로 다르게 회계처리하고 있었다. 이 기업들은 고객인 병원과 임플란트 장기공급계약을 맺지만, 병원이 아닌 금융회사로부터 제품판매대금을 받는다. 그리고 병원은 금융회사에 장기분할로 그 대금을 납부한다. 수익인식방법으로 오스템임플란트(주)는 금융기관으로부터 판매대금을 받으면 선수금으로 회계처리하고, 그 이후 제품을 병원으로 출고할 때 해당 선수금을 없애고 매출로 인식한다. 그러나 다른 업체인 (주)덴티움과 (주)디오는 금융기관으로부터 받은 금액을 대부분 매출로 인식해오고 있다. 이러한 회계처리는 매출과 순이익을 과대인식하게 될 것이다. 업계 경쟁 관계 등의 이유로 오스템임플란트(주)는 동종업체인 (주)덴티움과 (주)디오의 수익인식 회계처리에 문제가 있다고 관계기관에 감리를 요청하였다. 이에 따라 금융감독원은 (주)덴티움을, 한국공인회계사회는 (주)디오에 대한 특별감리를 실시했다. 관계기관의 감리의견은 각 기업이 업계의 관행에 따라 회계처리했다고 판단하고 오스템임플란트(주)가 제기한 수익인식에 관한 문제점은 지적하지 않았다. 두 기관은 모두 본질이 유사한 거래에 대하여 서로 다른 회계처리를 업계의 관행으로 인정한 것이다. 그런데 이와 별도로 관계기관은 감리를 받았던 기업들 모두 반품 회계처리가 적절하게 되지 않아서 수익성과 재무건전성이 과대평가되었음을 지적했다. 이에 대한 감리조치로 오스템임플란트(주)와 (주)덴티움은 경징계를, (주)디오는 중징계를 받았다. 본 연구는 임플란트 제조기업과 이와 유사한 매출구조를 갖는 제약 및 바이오산업의 수익인식 및 반품 회계처리를 이해하는 데 도움을 줄 것으로 판단한다. 그리고 동일한 회계이슈에 대하여 관계기관인 금융감독원과 한국공인회계사회의 감리정책이 서로 다른 문제점도 지적하고 있다. Dental implant manufacturing companies have adopted different accounting practices for the revenue recognition which has substantially same economic substance. The companies make long-term supply contracts with customer hospitals and are paid whole contract amounts in advance by the banks. The customer hospitals pay their bills in installment later to the banks. For revenue recognition, Osstem implant co.(Osstem) records advances from customers when it receives the contract amounts from the banks and recognizes sales revenue when it delivers its implant products to the customers. However, other implant companies, Dentium and Dio, record whole contract amounts as sales revenue at once and do not adjust their amounts for the undelivered products. This accounting method will overstate sales and net income for Dentium and Dio. Osstem asked the national supervisory institutions to do an official audit review for Dentium and Dio because they might manipulate sales and net income. The implant companies have competed to expand market shares and have not had good relationship each other. Osstem, Dentium and Dio became to have special audit reviews by the supervisory institutions. The institutions reported that Dentium and Dio did not violate accounting rules but followed industrial accounting convention. The institutions allowed different accounting methods for the transaction having same substance. Meanwhile, the supervisory institutions pointed out that all three implant companies did not keep proper accounting for the inventory returns and that they overstated profitability and financial condition. The institutions took disciplinary action for all the three companies.

Retention Esophagitis as a Significant Clinical Predictor of Progression to Esophageal Cancer in Achalasia

Haewon Kim,Hyojin Park,HeeSeung Choi,Yooju Shin,Hyunsung Park,Young Hoon Youn,Jie-Hyun Kim 대한소화기내시경학회 2018 Clinical Endoscopy Vol.51 No.2

Background/Aims: Chronic liquid and/or food stasis caused by retention esophagitis (RE) in achalasia is a notable endoscopic findingbecause of the presence of a thickened or whitish esophageal mucosa and histologically altered squamous hyperplasia. We aimed toidentify the clinical features of RE associated with achalasia and to clarify the clinical definition of RE in achalasia as a precancerouslesion identified by analyzing biomarker expressions. Methods: From 2006 to 2015, we retrospectively reviewed 37 patients with achalasia without previous treatment. Among them, 21patients had diagnostic findings of RE (RE+) and 16 patients had no diagnostic findings of RE (RE–). Immunohistochemical stainingof p53, p16, and Ki-67 was performed on the endoscopic biopsy tissues from the patients with achalasia and 10 control patients withnon-obstructive dysphagia. Results: The symptom duration and transit delay were significantly longer in the RE+ group than in the RE– group. We foundparticularly high p53 positivity rates in the RE+ group (p<0.001). The rate of p16 expression was also significantly higher in the RE+group than in the other two groups (p=0.003). Conclusions: A high p53 expression rate was more frequently found in the RE+ group than in the other two groups. RE could be ameaningful clinical feature of achalasia for predicting esophageal carcinogenesis.