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( Eirie Cho ),( Min Joo Kim ),( Jung Mi Chang ),( Seok Young Yoon ),( Gil Tae Lee ),( Yun Hyi Ku ),( Hong Il Kim ),( Myung Chul Lee ),( Guk Haeng Lee ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Intraoperative parathyroid hormone (IOPTH) assay is widely used in patients with primary hyperparathyroidism (PHPT). We investigated the usefulness of IOPTH assay in Korean patients with PHPT. Methods: We retrospectively reviewed the data of 33 patients with PHPT who underwent parathyroidectomy. Neck ultrasonography (US) and 99mTc-sestamibi scintigraphy (MIBI scan) were performed preoperatively and IOPTH assays were conducted. Results: The sensitivity of neck US and MIBI scans were 91% and 94%, respectively. A 50% decreased in parathyroid hormone (PTH) levels 10 minutes after excision of the parathyroid gland was obtained in 91% (30/33) of patients and operative success was achieved in 94% (32/33) of patients. The IOPTH assay was 91% true-positive, 3% true-negative, 0% false-positive, and 6% false-negative. The overall accuracy of the IOPTH assay was 94%. In 5 cases with discordant neck US and MIBI scan results, a sufficient decrease in IOPTH levels helped the surgeon confirm the complete excision of the parathyroid gland and perform no additional neck exploration. Conclusions: The IOPTH assay is an accurate tool for localizing hyperfunctioning parathyroid glands and is helpful for evaluating cases with discordant neck US and MIBI scan results.
Eirie Cho,Jung Mi Chang,윤석영,이길태,구윤휘,김홍일,이명철,이국행,김민주 대한내분비학회 2014 Endocrinology and metabolism Vol.29 No.4
Background: The intraoperative parathyroid hormone (IOPTH) assay is widely used in patients with primary hyperparathyroidism (PHPT). We investigated the usefulness of the IOPTH assay in Korean patients with PHPT. Methods: We retrospectively reviewed the data of 33 patients with PHPT who underwent parathyroidectomy. Neck ultrasonography (US) and 99mTc-sestamibi scintigraphy (MIBI scan) were performed preoperatively and IOPTH assays were conducted. Results: The sensitivity of neck US and MIBI scans were 91% and 94%, respectively. A 50% decrease in parathyroid hormone (PTH) levels 10 minutes after excision of the parathyroid gland was obtained in 91% (30/33) of patients and operative success was achieved in 97% (32/33) of patients. The IOPTH assay was 91% true-positive, 3% true-negative, 0% false-positive, and 6% false-negative. The overall accuracy of the IOPTH assay was 94%. In five cases with discordant neck US and MIBI scan results, a sufficient decrease in IOPTH levels helped the surgeon confirm the complete excision of the parathyroid gland with no additional neck exploration. Conclusion: The IOPTH assay is an accurate tool for localizing hyperfunctioning parathyroid glands and is helpful for evaluating cases with discordant neck US and MIBI scan results.
Multifocal nodular lymphoid hyperplasia of the lung
( Gil Tae Lee ),( Eun Kyoung Kim ),( Eirie Cho ),( Seung-sook Lee ),( Seo Yun Kim ),( Cheol Hyeon Kim ),( Hye-ryoun Kim ) 영남대학교 의과대학 2017 Yeungnam University Journal of Medicine Vol.34 No.1
Nodular lymphoid hyperplasia (NLH) is a benign lymphoproliferative disease that can affect the lung. Because of its rarity, little is known about the etiology and natural history of NLH. Most cases are usually asymptomatic and found incidentally on imaging studies. Imaging finding of NLH has shown most commonly as a solitary lesion, although multifocal pulmonary nodules may be seen. Surgical resection has proved curative in the cases previously described. We report a rare case of NLH in a 55 year-old man who presented with bilateral multiple pulmonary nodules on chest radiography. Open biopsy was performed from the upper and lower lobe of the left lung. The lesions were pathologically diagnosed as pulmonary NLH. Multifocal residual nodules in both lungs remain stable without spontaneous regression during the 3 years of follow-up.
Multifocal nodular lymphoid hyperplasia of the lung
Lee, Gil Tae,Kim, Eun Kyoung,Cho, Eirie,Lee, Seung-Sook,Kim, Seo Yun,Kim, Cheol Hyeon,Kim, Hye-Ryoun Yeungnam University College of Medicine 2017 Yeungnam University Journal of Medicine Vol.34 No.1
Nodular lymphoid hyperplasia (NLH) is a benign lymphoproliferative disease that can affect the lung. Because of its rarity, little is known about the etiology and natural history of NLH. Most cases are usually asymptomatic and found incidentally on imaging studies. Imaging finding of NLH has shown most commonly as a solitary lesion, although multifocal pulmonary nodules may be seen. Surgical resection has proved curative in the cases previously described. We report a rare case of NLH in a 55 year-old man who presented with bilateral multiple pulmonary nodules on chest radiography. Open biopsy was performed from the upper and lower lobe of the left lung. The lesions were pathologically diagnosed as pulmonary NLH. Multifocal residual nodules in both lungs remain stable without spontaneous regression during the 3 years of follow-up.
( Seok Young Yoon ),( Min Joo Kim ),( Kichul Shin Shin ),( Eirie Cho ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
We report a rare case of radioactive iodine (RAI)-induced Graves` disease in patient with toxic adenoma. Forty two-year-old woman was presented with neck masses. Hot nodule on thyroid scan suggested toxic adenoma and she got RAI treatment. Three months later, she complained thyrotoxic symptoms such as weight loss, palpitation, diarrhea, and menstrual irregularity. Thyroid scan showed diffuse increased uptake while the previous toxic adenoma became cold nodule. Thyroid-stimulating hormone receptor antibody increased. It suggested Graves` disease and she took anti-thyroid drug. Physicians keep RAI-induced Graves` disease in mind when thyrotoxicosis occurred after RAI treatment.