Elderly kidney transplant recipients have favorable outcomes but increased infection-related mortality

임정훈,Lee Ga Young,Jeon Yena,Jung Hee-Yeon,Choi Ji Young,CHO, JANG-HEE,Park Sun Hee,김용림,Kim Hyung-Kee,Huh Seung,유은상,Won Dong Il,Kim Chan-Duck 대한신장학회 2022 Kidney Research and Clinical Practice Vol.41 No.3

Background: The number of elderly patients with end-stage kidney disease has been increasing, but the outcomes of kidney transplants (KT) remain poorly understood in elderly patients. Therefore, we evaluated the clinical outcomes of elderly KT recipients and analyzed the impact of elderly donors. Methods: This retrospective cohort study included patients who underwent KT between 2000 and 2019. KT recipients were divided into four groups according to a combination of recipient and donor age (≥60 or <60 years); elderly recipients: old-to-old (n = 46) and young-to-old (n = 83); young recipients: old-to-young (n = 98) and young-to-young (n = 796). We compared the risks of mortality, graft failure, and acute rejection between groups using Cox regression analysis. Results: The incidence of delayed graft function, graft failure, and acute rejection was not different among groups. Annual mean tacrolimus trough level was not lower in elderly recipients than young recipients during 10-year follow-up. Mortality was significantly higher in elderly recipients (p = 0.001), particularly infection-related mortality (p < 0.001). In multivariable Cox regression analysis, old-toold and young-to-old groups had increased risk of mortality (adjusted hazard ratio [aHR], 2.89; 95% confidence interval [CI], 1.14– 7.32; p = 0.03; aHR, 3.06; 95% CI, 1.51–6.20; p = 0.002). However, graft failure and acute rejection risks were not increased in elderly recipients. Conclusion: In elderly recipients, graft survival and acute rejection-free survival were not inferior to those of young recipients. However, mortality, especially risk of infection-related death, was increased in elderly recipients. Thus, low immunosuppression intensity might help decrease mortality in elderly recipients.

시험성토 단면에서의 다짐에너지에 따른 LFWD 변형계수의 변화

최찬용(Choi Chan-Young),김현기(Kim Hyun-Ki),배재훈(Bae Jae-Hoon) 한국철도학회 2008 한국철도학회 학술발표대회논문집 Vol.- No.-

PLT where from site is used mainly with compaction maintenance of quality, CPLT and LFWD, in order to be a Young"s modulus of using a direct arrival wave executed a site experiment. According to the roller compaction number of times measured the degree which changes and a promise management aptitude evaluation executed.

Peroxide 개질에 따른 Nylon 12 elastomer의 특성 연구

최명찬 ( Myung Chan Choi ),정지연 ( Ji Yeon Jung ),장영욱 ( Young Wook Chang ) 한국고무학회 2013 엘라스토머 및 콤포지트 Vol.48 No.1

용융상태에서 nylon 12 elastomer에 소량의 dicumyl peroxide (DCP) 와 triallyl cyanuate (TAC)를 첨가하여 nylon 12 elastomer를 부분적으로 가교시켰으며, 이에 따른 nylon 12 elastomer의 기계적, 동적기계적 그리고 유변학적 특성을 tensile test, DMA, small amplitude oscillating rheometer를 이용하여 각각 알아보았다. TAC의 함량이 증가함에 따라 인장탄성률과 영률은 증가하고, 파단신율은 감소하였다. DMA 측정결과, DCP로 부분적으로 가교시킨 nylon 12 elastomer의 PTMG상의 유리전이온도는 순수한 nylon 12 elstomer에 비해 증가하였고, storage modulus는 nylon 12상의 용융온도 이상에서도 거의 일정한 값을 나타내었다. 부분적으로 가교시킴에 따른 유변학적 특성의 변화는 TAC의 함량이 증가함에 따라 solid like behavior와 shear thinning behavior가 점점 뚜렷하게 나타남을 알 수 있었다. 이로부터 nylon 12 elastomer를 용융상태에서 부분적으로 가교시킴으로써 용융가공성을 저하시키지 않으면서, 기계적 물성은 효과적으로 향상시킬 수 있었으며, 특히, nylon 12 elastomer의 사용가능 온도범위를 증가시킬 수 있었다. Nylon 12 elastomer was slightly crosslinked in molten state by the addition of small amount of dicumyl peroxide (DCP) as a crosslink agent and triallycyanuate (TAC) as a co-agent during melt compounding at 160 oC in an internal mixer. The effect of the peroxide crosslinking on mechanical, dynamic mechanical and rheological properties of the nylon 12 elastomer was investigated by means of tensile testing, dynamic mechanical analysis (DMA) and small amplitude oscillating rheometer, respectively. With modification, there is an improvement in tensile modulus and Young`s modulus with decease in elongation at break. DMA results for peroxide modified nylon 12 elastomers demonstrated that the glass transiaiton temperature of PTMG segment shifted to higher temperature and the storage modulus remained constant above the melting temperature of nylon 12 segments. Melt rheological studies revealed that the peroxide modified nylon 12 elastomer exhibited a more solid like behavior and stronger shear thinning behavior compared to neat nylon 12 elastomer, which was more prominent at higher TAC content in the polymer matrix. The peroxide modified nylon 12 elastomer exhibited good elastic recoverability and improved mechanical properties without sacrificing melt processibilty, and especially the service temperature range increased as compared to neat nylon 12 elastomer.

토안에서 금판 삽입술의 효과

최시환,박영규,박우찬 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

Lagophthalmos can result in serious keratopathy because of corneal exposure and inadequate lacrimation. Four patients underwent gold plate insertion to rehabilitate paralysis of the eyelid caused by facial nerve palsy. Gold plate insertion resulted in exellent eyelid closure, protection, and cosmesis. There were no infections or extrusions. Lagophthalmos and exposure keratitis were resolved or were significantly improved in these patients. In selected patients this technique reestablishes a voluntary blink and provides corneal protection without the limitation of tarsorrhaphy. Gold plate insertion has become the procedure of choice for eyelid rehabilitation.

제주도 남방 연안역의 4월달 해수특성

최영찬,문영석 濟州大學校海洋硏究所 1991 해양과환경연구소 연구논문집 Vol.15 No.-

1990년 4월달 제주도 남방해역을 동남방, 남방, 서남방해역으로 구분하여 11개 정점에서 물리화학적인 분석을 실시하였다. 해역별 영양염류중 인산인에 대한 무기질소성분의 비(N/P)는 동남방해역이 15.4, 남방해역이 13.8, 서남방해역이 9.4로서 해역 구분이 뚜렷하게 나타나고 있었다. 규산규소는 서남방해역이 가장 높은 농도를 보였으며, 표, 저층간의 농도변화폭이 가장 적어 연직혼합이 가장 잘 이루어지는 용승역임을 시사해 주고 있다. 클로로필-a 농도로 볼때 서남방해역이 1㎎/㎥이상으로서 부영양상태역으로, 동남방 외해역(0.5㎎/㎥이하)은 빈영양상태역으로 구분되어질 수 있다. 이와같은 농도분포로 보아 Kuroshio등 빈영양상태의 외양성해류가 제주도 남방역중 동남방역에 더 영향을 미치고 있다고 생각된다. Through 11 obesrvaational stations in the southern seas off Cheju Island, which are divided in details into the southeastern and the southern and the southwestern sections, physical and chemical analysis have been performed in April, 1990. Each section is well distinguished in the ratio of nitrogen to phosphate (N/P) as 15.4 in the southeastern section, 13.8 in the southern section, and 9.4 in the southwestern section. The southwestern section shows the highest concentration of silicate and also small variations between the surface and thebottom layers. It suggests upwellings which cause well-mixings between the surface and the bottom layers. The concentrations of chlorophyll-a are over 1㎎/㎥ (rich) in the southwestern section, and below 0.5㎎/㎥ (poor) in the southeastern section. These distributions show that Kuroshio open-sea waters of poor nutrients affect more the southeastern section.

제주도 남방 연안역의 4월달 해수특성

최영찬,문영석 제주대학교 해양연구소 1991 해양자원연구소연구보고 Vol.15 No.-

Through 11 observational stations m the southern seas off Cheju Island, which are divided m details mto the Southeastern and the southern and the southwestern sections, physical and chemical analysis have been performed in April 1990. Each section is well distinguished in the ratio of nitrogen to phosphate (N/P) as 15.4 in the southeastern section, 13.8 in the southern section, and 9.4 in the southwestern section. The southwestern section shows the highest concentration of silicate and also small variations between the surface and the bottom layers. It suggests upwellings which cause well-mixings between the surface and the bottom layers. The concentrations of chlorophyll-a are over 1mg/㎥ (rich) m the southwestern section, and below 0.5 mg/㎥ (poor) in the southeastern section. These distributions show that Kuroshio open-sea waters of poor nutrients affect more the southeastern section.

公害規制가 貿易패턴에 미치는 影響

崔文燦,徐英哲 東亞大學校 經營問題硏究所 1994 經營論叢 Vol.15 No.-

제주도 서부 연안역의 생물생태학적 기초연구(I) : 고산주변 연안역의 해수특성

최영찬,이준백,고유봉 제주대학교 해양연구소 1994 해양자원연구소연구보고 Vol.18 No.-

제주시내 주요 하천의 이화학적 수질조사 연구

최영찬,박길순 제주대학교 1986 논문집 Vol.23 No.-

Six different sites in major streams of Cjeju City were selected for the surveying of chemical water quality from July 1984 to June 1985. The results are as follows. 1. pH range and average were 7.2-8.7 and 7.7 respectively. No significant differecnces in seasons and sites were obseved 2. DO were 0.33-9.10 ppm and 3.53 ppm respectively which belong to 3rd class in the environmental criteria for daily life and was bellow the concentrates of mesosaprobic waters marine organism (5.0ppm). 3. BOD were 17.5-232.4ppm, 64.9 ppm respectively which was more than two times higher than 30ppm-the water quality criteria for sewage treatment terminal. 4. COD were 12.6-102.1pprn, 30.2ppm respectively which was three times higher than l0ppm-the environmental conservation criteria for daily life. 5 NH^(+)_(4)-N which is early decomposing product of organic pollution material were 3.01 -29.98ppm, 4.11ppm respectively and showed higher figure than other regions stream water.

선속 변화에 의한 능동형 횡 동요감쇠장치의 효과

최찬문,안장영,서두옥,정용진 濟州大學校 海洋硏究所 2004 해양과환경연구소 연구논문집 Vol.28 No.1

제주대학교 실습선 아라호에 장착된 능동형 횡 동요 감쇠장치의 성능이 선박의 속력과의 관계를 파악 하기 위하여 선박을 정지, 미속, 중속, 전속으로 구분하여 횡 동요 감쇠장치를 정지(Passive A.R.T), 작동(Active A.R.T)을 했을 때 경사계에 의한 횡 동요각 및 종 동요각, 풍속계에 의한 풍속의 변화에 의한 분석한 결과를 요약하면 다음과 같다. 1. 선박이 정지했을 때가 능동형 횡 동요 감쇠장치의 1/3, 1/10 횡 동요각 유의 진폭에서 감소률이 가장 높아 47.2%, 50.3%를 나타냈으며, 반면에 중속인 경우 가장 낮은7.1%, 7.4% 나타내므로, 이 장치는 선속의 변화에 차이가 있는 것으로 판단된다. 2. 선속의 변화에 따라 그 효율이 많은 차이가 있으므로 이 장치를 장착한 선박의 운항자는 이를 감안하여 작동하여야 할 것으로 생각되며, 통계분석 결과에 의해서 선속과 감소률의 관계를 회귀분석식으로 나타내어 보면 다음과 같았다. 즉, 횡동요각 유의 진폭 (Amplitude of and significant roll (φ_(1/3)) : y= -3.233χ + 45.613 횡동요각 유의 진폭 (Amplitude of and significant roll (φ_(1/10)) : y= -3.157χ + 46.840을 각각 얻을 수 있었다. This experimental paper deals with the performance of tanks that are turned the active A.R.T(Anti-Rolling Tank) when the fluid transfers from wing tanks to the opposite tank by the power developed by the automatic control system (INTERING Stabilizer), which was installed in the fishery training ship T/S. A - RA (G/T : 990 tons) of Cheju National University. In this paper, the author has tested the performance of INTERING Stabilizer from the signals obtained by the inclinometer in irregular waves and compared with the results obtained in passive mode operation at stop and at various ship speeds. The performances of the system were confirmed the results as follows through the tests : 1. The Rates of reduction in significant roll(φ_(1/3)) of performance of Active-Rolling Tank at stop. dead slow ahead, half ahead, full ahead were obtained 47.2%, 26.3%, 7.7% 9.7%, respectively. 2. The operators had to consider to be different to change according to the various ship speeds for working. and the author could get the linea regressions about the rates of reduction at the results of a statistical analysis through the time histories of rolling angles in A.R.T. in irregular waves using various ship's speeds. Rates of reduction in significant roll(φ_(1/3)) : y = -3.233χ + 45.613 Rates of reduction in significant roll(φ_(1/10)) : y = -3.157χ + 46.840