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주창근,강영호,손기수 慶北大學校 1971 論文集 Vol.15 No.-
Kinematics of special relativity is depicted through space-time diagrams, whereby Doppler effects can be presented in a graphical form rather than analytic. Such space-time diagrams, which are a variation of Minkowsky's, are then applied to the derivation of Einstein's formula E=hν for the photon.
전신적인 피부병변으로 발현한 모세포성 NK세포 림프종 1예
이근욱,윤탁,김동완,김태유,허대석,박영주,김노경 대한내과학회 2004 대한내과학회지 Vol.66 No.4
저자들은 다른 장기의 침범 없이 전신적인 피부 병변만으로 발현한 모세포성 NK세포 림프종 1예를 국내에서 처음으로 경험하였기에 이를 문헌고찰과 함께 보고하는 바이다. Reports of blastic natural killer (NK)-cell lymphoma are rare. In previous reports, primary cutaneous blastic NK-cell lymphomas were even rarer. In asian patients, most CD56+ lymphomas are classified as nasal type extranodal NK/T-cell lymphoma and mostly associated with the presence of Epstein-Barr virus (EBV) and have an aggressive clinical course. Few cases of blastic NK-cell lymphoma were reported previously in Korea but there was report about blastic NK-cell lymphoma initially presented as disseminated skin lesions without any other organ involvement. We report such a young patient who was treated by systemic chemotherapy.
간 및 자궁에 전이된 췌장의 Somatostatinoma
김태유,박영이,임영혁,허대석,방영주,김노경,김선희,김철우 대한내과학회 1993 대한내과학회지 Vol.44 No.5
저자등은 췌장 부위의 종양과 간과 자궁으로의 전이가 있으면서, 일반적인 췌담관계의 악성 종양과는 다른 임상경과를 갖고, 면역 화학적 조직 검사와 혈장 somatostatin의 측정으로 입증된 somatostatinoma 1예를 경험하여 보고하는 바이다. Somatostatinoma, a rare endocrine tumor, is characterized by diarrhea, steatorrhea, diagetes, and cholelithiasis due to excessive production of somatostatin. We report a case of a 32-year-old woman with pancreatic somatostatinoma that methastasized to the liver and uterus. The patient first presented with jaundice and diarrhea, and subsequently ascites and vaginal bleeding. The diagnosis was made by the pathologic examination, immunohistochemistry, and elevated plasma level of somatostatin. The patient was transiently improved with recombinant γ-interferon therapy.
악성 흉막액에 대한 흉막강내 OK - 432 주입의 치료 효과
방영주(Yung Jue Bang),서철원(Chol Won Seo),이재훈(Jae Hoon Lee),신동복(Dong Bok Shin),강윤구(Yoon Koo Kang),박근칠(Keun Chil Park),김노경(Noe Kyeong Kim) 대한내과학회 1989 대한내과학회지 Vol.36 No.4
N/A OK-432 has been shown to have antitumor activity in cancer patients, and intrapleural injection of OK-432 had also been shown to cause reduction or disappearance of pleural effusions and/or tumor cells in pleural effusions of cancer patients. Forty patients with malignant pleural effusions were treated with intrapleural administration of OK-432. Their age ranged from 20 to 80 years with a median of 56 years, and the male to female ratio was 24:16. Primary tumor sites were lung in 30 patients, stomach in 3, colon in 1, ovary in 1, and 5 patients had adenocarcinoma of unknown primary site. Cytologic examinations of pleural fluid were positive in 30 patients, and 10 patients without cytologic proof had exudative effusions with elevated levels of carcinoembryonic antigen. Their performance status was ECOG grade 1 in 9, 2 in 18, and 3 in 13 patients. One to three courses of intrapleural injection of OK-432 were tried weekly (mean 1.3 courses) without any concomitant anticancer treatment. The responses were categorized as objective response or failure. Seven patients were not evaluable for response because of early death without pleural effusion in two, protocol violation in one, and lost to follow-up in four. Twenty-four patients (72.7%) achieved objective responses among 33 evaluable patients. Response duration ranged from 4+ to 59 weeks with a median of 52 weeks. Common toxicities included fever and chill (38/52 courses), and pleuritic chest pain (24/52), but those symptoms were tolerable. These results show that intrapleural administration of OK-432 appears to be effective in the control of malignant pleural effusions with acceptable toxicity.