Shear-Wave Elastography of the Breast: Added Value of a Quality Map in Diagnosis and Prediction of the Biological Characteristics of Breast Cancer

Xueyi Zheng,Yini Huang,Yubo Liu,Yun Wang,Rushuang Mao,Fei Li,Longhui Cao,Jianhua Zhou 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.2

Objective: To determine the added value of a shear-wave elastography (SWE) quality map (QM) in the diagnosis of breast lesions and in predicting the biological characteristics of invasive breast cancer. Materials and Methods: Between January 2016 and February 2019, this study included 368 women with 368 pathologically proven breast lesions, which appeared as poor-quality regions in the QM of SWE. To measure shear-wave velocity (SWV), seven regions of interest were placed in each lesion with and without QM guidance. Under QM guidance, poor-quality areas were avoided. Diagnostic performance was calculated for mean SWV (SWVmean), max SWV (SWVmax), and standard deviation (SD) with QM guidance (SWVmean + QM, SWVmax + QM, and SD + QM, respectively) and without QM guidance (SWVmean - QM, SWVmax - QM, and SD - QM, respectively). For invasive cancers, the relationship between SWV findings and biological characteristics was investigated with and without QM guidance. Results: Of the 368 women (mean age, 47 years; SD, 10.8 years) enrolled, 159 had benign breast lesions and 209 had malignant breast lesions. SWVmean + QM (3.6 ± 1.39 m/s) and SD + QM (1.02 ± 0.84) were significantly different from SWVmean - QM (3.29 ± 1.22 m/s) and SD - QM (1.46 ± 1.06), respectively (all p < 0.001). For differential diagnosis of breast lesions, the sensitivity and areas under the receiver operating characteristic curve (AUC) of SWVmean + QM (sensitivity: 89%; AUC: 0.932) were better than those of SWVmean - QM (sensitivity, 84.2%; AUC, 0.912) (all p < 0.05). There was no significant difference in sensitivity and specificity between SD + QM and SD - QM (all p = 1.000). Among the biological characteristics of invasive cancers, lymphovascular involvement, axillary lymph node metastasis, negative estrogen receptor status, negative progesterone receptor status, positive human epidermal growth factor receptor status, and aggressive molecular subtypes showed higher SWVmean + QM (all p < 0.05), while only lymphovascular involvement showed higher SWVmean - QM (p = 0.036). Conclusion: The use of QM in SWE might improve the diagnostic performance for breast lesions and facilitate prediction of the biological characteristics of invasive breast cancers.

An Efficient Method for Calculating the Intersection Curve between a Ruled Surface and a Plane

Xueyi Li,Shoubo Jiang,Binbing Huang,Qingliang Zeng 보안공학연구지원센터(IJSIP) 2013 International Journal of Signal Processing, Image Vol.6 No.6

Finite Time Controller Design of Nonlinear Quantized Systems with Nonstrict Feedback Form

Xueyi Zhang,Fang Wang,Lili Zhang 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.1

This article considers a finite-time control problem of nonlinear quantized systems in complex environments. The controlled system is in a non-strict feedback form. By applying a nonlinear decomposition of hystereticquantizer, the quantization issue is tackled successfully. By employing a structural property of radial basis function(RBF) neural networks (NNs), the conventional backstepping method is extended to non-strict feedback nonlinearquantized systems. Based on the finite time stability criterion, a new adaptive neural control scheme is presented. The constructed neural controller can ensure the transient performance of nonlinear quantized systems.

The Development of Catering Giant Haidilao: The Leader in Quality Tracks

Li Xueyi,Jiang Xinmei,Zhang Siyu,Yang Xishe,Yang Yang Academy of Asian Business (AAB) 2022 Academy of Asian Business Review Vol.8 No.1

The purpose of this case study is to analyze the success story of Haidilao, a leading Chinese restaurant company known for its supreme service and innovative business model. The report is presented in three parts. The first part examines the history of Haidilao, discussing the background of its founding, its current position, and important turning points.The second section explores the factors behind Haidilao's success, categorized by internal management and external strategies. The unique corporate values of Asian companies that Haidilao possesses are highlighted. The third section discusses the internal and external challenges faced by Haidilao and the suggested solutions. Finally, this conclusion examines what we can learn from Haidilao's success. Against the backdrop of rapid changes in the world's restaurant industry, this case study hopes to provide insights for the emerging restaurant industry in Asia by analyzing the success story of a hot pot empire. Since Haidilao has a unique Asian-style business strategy in its development process, it is hoped that those Asian companies in the midst of globalization will take the best from the bad and learn from Haidilao's practices in industry chain layout, new technology application, and human resource management while learning valuable lessons from Haidilao's business process.

Numerical study of rock-breaking performance of cutters in heterogeneous sand cobble ground

Jin Guo,Xiangwei Kong,Liu Cheng,Xueyi Li 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.6

Further research into tunneling performance in heterogeneous sand cobble ground demands an accurate numerical model of actual formation. In this paper, the ground model composed of spherical sand and ellipsoidal cobble was constructed to study the rockbreaking performance by using the discrete element method. The shape and physical parameters of sand and cobble were obtained on the basis of field test data. Then, the ground model was constructed to simulate the rock-breaking process of the cutterhead. The results show that the center cutter has a high flat wear percentage. With the decrease in cobble content (CC), the cracks between cutters are not connected effectively, thereby resulting in lower rock-breaking quantity. Finally, the influences of CC on the optimal parameters and crack propagation were analyzed. The results indicate that the rock-breaking performance in the ground with a low CC can be improved by increasing penetration and reducing cutter spacing.

Load Transferring Mechanism and Design Method of Effective Detailings for Steel Tube-Core Concrete Interaction in CFT Columns with Large-Section

Li, Yuanqi,Luo, Jinhui,Fu, Xueyi Council on Tall Building and Urban Habitat Korea 2018 International journal of high-rise buildings Vol.7 No.3

Two novel types of construction detailings, including using the distributive beam and the inner ring diaphragm in the joint between large-section CFT columns and outrigger truss to enhance the transferring efficiency of huge vertical load, and using the T-shaped stiffeners in the steel tube of large-section CFT columns to promote the local buckling capacity of steel tubes, were tested to investigate their working mechanism and design methods. Experimental results show that the co-working performance between steel tube and inner concrete could be significantly improved by setting the distributive beam and the inner ring diaphragm which can transfer the vertical load directly in the large-section CFT columns. Meanwhile, the T-shaped stiffeners are very helpful to improve the local bulking performance of steel tubes in the column components by the composite action of T-shaped stiffeners together with the core concrete under the range of flange of T-shaped stiffeners. These two approaches can result in a lower steel cost in comparison to normal steel reinforced concrete columns. Finally, a practical engineering case was introduced to illustrate the economy benefits achieved by using the two typical detailings.

Local Joule heating targets catalyst surface for hydrocarbon combustion

Qian Xiong,Xingbao Zhu,Ri He,Xueyi Mei,Yexin Zhang,Zhicheng Zhong,Wei Zhao,Weiming Nie,Jian Zhang 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.117 No.-

Most industrial catalytic reactions are achieved by external heating and catalysts are entirely heated tooffer enough thermal energy to surface active sites. However, there is an inherent drawback that mostinput energy is dissipated into the bulk while minor is donated to the surface, leading to high energywaste. Here, we proposed a so-called local Joule heating method via passing an electric current throughpacked catalyst nanoparticles with a large contact resistance, which can generate sufficient heat to targetat the surface region. We selected hydrocarbon combustion, a common way to eliminate unburned pollutants,as a probe reaction and used the conductive antimony-doped tin oxide (ATO) as a model catalyst. Compared with traditional external heating, this method consumed one order lower energy input,reduced the macroscopically average temperature for same conversion by 100 C, improved the durabilitywith smaller activity loss within 100 h operation, and suppressed water poisoning effect by 60 %. Also, the combustion was sparked in seconds by pulsing electric current into the catalyst bed, allowing anapplication in prompt treatment of leaked hydrocarbons. The local Joule heating between contactednanoparticles, which could focus thermal energy on catalyst surface, is prospective to improve catalysisefficiency.

Stenotrophomonas maltophilia outer membrane protein A induces epithelial cell apoptosis via mitochondrial pathways

Xin Wang,Yan Li,Xueping Tang,Xueyi Shang,Zunquan Zhao,Yongqiang Jiang,Yan Li 한국미생물학회 2020 The journal of microbiology Vol.58 No.10

Stenotrophomonas maltophilia (S. maltophilia) is a common opportunistic pathogen in intensive care units and causes infections most often after surgeries in immune-compromised patients such as those undergoing chemotherapy. Outer membrane protein A (OmpA) is the most abundant of the outer membrane proteins in S. maltophilia. Previous studies on OmpA usually focus on its interaction with the host cells and its role in vaccine development. However, the impact of OmpA on the virulence of S. maltophilia to host cells and the effects on apoptosis remain unclear. In this study, we exposed purified recombinant S. maltophilia OmpA (rOmpA) to HEp-2 cells and investigated the effects of OmpA on epithelial cell apoptosis. Morphologic and flow cytometric analyses revealed that HEp-2 cells stimulated with rOmpA multiple apoptosis features, including nuclear roundness and pyknosis, chromatin aggregation, and phosphatidylserine eversion. We found that rOmpA regulated the protein levels of Bax and Bcl-xL in HEp-2 cells, leading to changes in mitochondria permeability and the release of cytochrome c and apoptosis-inducing factors into the cytoplasm. These subsequently activate the caspase-9/caspase-3 pathway that promote apoptosis. We also observed that rOmpA enhanced the generation of reactive oxygen species and increased intracellular Ca2+ levels in HEp-2 cells. Collectively, our data suggested that rOmpA induced epithelial cells apoptosis via mitochondrial pathways.

Damage Mechanism of Broad-narrow Joint of CRTSII Slab Track under Temperature Rise

Xiaokai Liu,Wenhao Zhang,Jieling Xiao,Xueyi Liu,Wei Li 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.5

There is two typical damage pattern at broad-narrow joint of CRTSII slab track breakage of narrow joint and fracture at junction between broad joint and narrow joint. This paper aims to study the damage mechanism and develop of broad-narrow joint of CRTSII slab track and put forward the methods to reduce the damage. Based on damaged plasticity model for concrete and cohesive zone model, the damage mechanism and development process of broad-narrow joint are analyzed in this study. The unequal width of broad joint and narrow joint, different concrete strength between broad-narrow joints and slab and slab integrity reducing due to the interface are the main reason for the typical damage. It is suggested to set the same width of broad joint and narrow joint, set the same strength of broad-narrow joint and slab and enhance the integrity of the slab by chipping or adding adhesives, among which the former two methods are more effective. Breakage of narrow joint is a gradual compression damage due to the lower concrete strength than slab. Fracture at the junction between narrow joint and broad joint is a mutational tension damage due to the unequal width of broad joint and narrow joint. The temperature gradient has significant effect on the compression damage, but small to the tension damage, it has the risk of complete destruction under extreme conditions.

Experimental study on through-beam connection system for concrete filled steel tube column-RC beam

Chunyu Tian,Congzhen Xiao,Tao Chen,Xueyi Fu 국제구조공학회 2014 Steel and Composite Structures, An International J Vol.16 No.2

A new through-beam connection system for a concrete filled steel tube column to RC beam is proposed. In this connection, there are openings on the steel tube while the reinforced concrete beams are continuous in the joint zone. The moment and shear force at the beam ends can be transferred to column by continuous rebar and concrete. The weakening of the axial load and shear bearing capacity due to the opening of the steel tube can be compensated by strengthening steel tube at joint zone. Using this connection, construction of the joint can be made more convenient since welding and hole drilling in situ can be avoided. Axial compression and reversed cyclic loading tests on specimens were carried out to evaluate performance of the new beam-column connection. Load-deflection performance, typical failure modes, stress and strain distributions, and the energy dissipation capacity were obtained. The experimental results showed that the new connection have good bearing capacity, superior ductility and energy dissipation capacity by effectively strengthen the steel tube at joint zone. According to the test and analysis results, some suggestions were proposed to design method of this new connection.