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      • KCI등재

        Nursing Students’ Clinical Competence and Decision-Making : Impact of a Multiple-components Practice-based Learning

        Xianqi Gao,Yoonjeong Lee,Moonkyoung Park 대한산업경영학회 2024 산업융합연구 Vol.22 No.3

        본 연구는 단일그룹 사전-사후 실험설계를 통해 다중요소 실습기반교육의 간호학생의 임상수행능력과 임상의사결정 에 대한 효과를 탐색하는 것을 목적으로 하였다. 2020년 5월 4일부터 29일까지 임상실습 경험이 없는 간호학과 3학년 학생 총 60명이 2팀으로 나누어 2주씩 다중요소 실습기반교육에 참여했고, 최종 51명의 자료가 분석에 포함되었다. 연구결과 임 상수행능력, 임상의사결정 자신감은 실습교육전에 비해 유의미하게 상승하였고, 임상의사결정에 대한 불안은 유의미하게 감 소하였다. 간호학생을 위한 다중요소를 포함한 실습교육은 환자 간호를 위한 수행 자신감을 향상시키고, 임상적 의사결정에 대한 자신감을 증가와 불안 완화의 교육방법으로 적용될 수 있다. This study is a one-group pre-post experimental design that investigates the effects of a practicebased learning program with multiple components on the clinical competence of nursing students, and clinical decision-making. From May 4 to 29, 2020, a total of 60 third-year nursing students with no clinical practice experience were divided into two teams and participated in multi-component practice-based education for two weeks each, and the data of the final 51 students were included in the analysis. Following the practicum, there was a significant increase in clinical competence (t=-4.74, p <.001) and self-confidence in clinical decision-making (t=-8.41, p <.001), and a decrease in anxiety related to clinical decision-making (t=2.54, p= .014). The findings suggest that a multi-component, practice-based learning approach for nursing students can enhance their clinical competence, reduce preclincal anxiety and increase confidence in clinical decision-making in patient care.

      • KCI등재

        Modified Slip Surface Stress Method for Potential Slip Mass Stability Analysis

        Haitao Zhang,Xianqi Luo,Jinfeng Bi,Zijing Guo 대한토목학회 2019 KSCE Journal of Civil Engineering Vol.23 No.1

        A modified slip surface stress method is proposed with the concept of vector sum and rigorous force analysis. Theoretically, the proposed method could degenerate into the existing methods by adding the corresponding assumptions. Through five typical slope cases, comparisons are made among the Factor of Safety (FoS) calculated by the proposed method and others. Results show that the proposed method could evaluate slopes at the limit state. Moreover, the proposed method is capable to calculate the FoS of the potential slip mass for both homogeneous and heterogeneous cases with regular or irregular slip surface in both two- and three-dimension spaces. Also, the proposed method could give the potential slip direction of a slope, which is useful for the design of measures to reinforce the slope.

      • KCI등재

        Effects of rolling-cutting processing parameters on micro-grooved strips forming

        Baoyu Zhang,Xianqi Fan,Guocheng Shi,Yang Zhou,Di He,Wenjun Deng 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.1

        High heat flux density in the micro-electronics field urges the demand for functional surface for heat transfer. Micro-grooved surface is the classical heat transfer surface because of the larger specific area and better inducement of turbulence. A novel micro-grooved surface manufacturing process, the rolling-cutting process, is proposed to produce microgrooved strips. Experiments are conducted to analyze the influence of processing parameters on the strips forming. The optimal combination of processing parameters is given to attain the micro-grooved strips with higher fins height and thinner base thickness. Additionally, the obtained strips are of three-dimensional structures with serrated bulges at the top. The difference between the material flow of serrated bulges and strip base is discussed, and the forming of serrated bulges is mainly due to inhomogeneous sinuous material flow.

      • KCI등재

        Tissue Engineering with Compact Bone-Derived Cell Spheroids Enables Bone Formation around Transplanted Tooth

        Matsumura Nahomi,Li Xianqi,Uchikawa-Kitaya Eri,Li Ni,Dong Hongwei,Chen Kai,Yoshizawa Michiko,Kagami Hideaki 한국조직공학과 재생의학회 2022 조직공학과 재생의학 Vol.19 No.2

        BACKGROUND: Although tooth transplantation is a desirable treatment option for congenital defects of permanent teeth in children, transplantation to a narrow alveolar ridge is not feasible. In this study, we investigated the possibility of bone tissue engineering simultaneously with tooth transplantation to enhance the width of the alveolar bone. METHODS: Bone marrow mononuclear cells or cortical bone-derived mesenchymal stromal cell spheroids were seeded onto atelocollagen sponge and transplanted with freshly extracted molars from mice of the same strain. New bone formation around the tooth root was evaluated using micro-computed tomography and histological analysis. Tooth alone, or tooth with scaffold but without cells, was also transplanted and served as controls. RESULTS: Micro-computed tomography showed new bone formation in the furcation area in all four groups. Remarkable bone formation outside the root was also observed in the cortical bone-derived mesenchymal stromal cell group, but was scarce in the other three groups. Histological analysis revealed that the space between the new bone and the root was filled with collagen fibers in all four groups, indicating that the periodontal ligament was maintained. CONCLUSION: This study demonstrates the potential of simultaneous alveolar bone expansion employing bone tissue engineering approach using cortical bone-derived mesenchymal stromal cell spheroids for tooth transplantation. The use of an orthotopic transplantation model may further clarify the feasibility and functional recovery of the transplanted tooth over a longer period.

      • KCI등재

        Effect of TNF-α and IL-6 on Compact Bone-Derived Cells

        Zhang Yiming,Li Xianqi,Chihara Takahiro,Dong Hongwei,Kagami Hideaki 한국조직공학과 재생의학회 2021 조직공학과 재생의학 Vol.18 No.3

        Background: Although bone tissue engineering has already been applied clinically, its regeneration efficacy is not always sufficient. Local inflammatory cytokines are considered as the major factors that induce apoptosis of transplanted cells, thus leading to insufficient new bone formation. In this study, we focused on the effects of interleukin (IL)-6 and tumor necrosis factor-alpha (TNF-α) on differentiation and apoptosis of compact bone-derived cells (CBDCs). Methods: CBDCs were obtained from mouse legs and cultured. The effects of TNF-α and/or IL-6 on the osteogenic differentiation and apoptosis of CBDCs were analyzed in vitro. To confirm the expression of local inflammatory cytokines in vivo, CBDCs were transplanted to the back of immunocompetent mice. Results: IL-6 exerted inconsistent effects on the expression of the different osteogenic markers tested, while significantly upregulating Fas. By contrast, the addition of TNF-α dramatically reduced the expression of all tested osteogenic markers and increased Fas expression. The highest dose of IL-6 could partially reverse the repressive effect of TNF-α, while the addition of IL-6 further increased Fas expression in CBDCs compared to TNF-α alone. The results from in vivo experiments showed the presence of transplants with and without new bone formation. The transplants without bone formation were characterized by higher IL-6 and lower IL-10 expression than those with bone formation, while the expression of TNF-α did not show notable difference. Conclusion: The results of this study suggest an important role for IL-6 in modulating the efficacy of bone tissue engineering, which can affect osteogenic cells both positively and negatively. Background: Although bone tissue engineering has already been applied clinically, its regeneration efficacy is not always sufficient. Local inflammatory cytokines are considered as the major factors that induce apoptosis of transplanted cells, thus leading to insufficient new bone formation. In this study, we focused on the effects of interleukin (IL)-6 and tumor necrosis factor-alpha (TNF-α) on differentiation and apoptosis of compact bone-derived cells (CBDCs). Methods: CBDCs were obtained from mouse legs and cultured. The effects of TNF-α and/or IL-6 on the osteogenic differentiation and apoptosis of CBDCs were analyzed in vitro. To confirm the expression of local inflammatory cytokines in vivo, CBDCs were transplanted to the back of immunocompetent mice. Results: IL-6 exerted inconsistent effects on the expression of the different osteogenic markers tested, while significantly upregulating Fas. By contrast, the addition of TNF-α dramatically reduced the expression of all tested osteogenic markers and increased Fas expression. The highest dose of IL-6 could partially reverse the repressive effect of TNF-α, while the addition of IL-6 further increased Fas expression in CBDCs compared to TNF-α alone. The results from in vivo experiments showed the presence of transplants with and without new bone formation. The transplants without bone formation were characterized by higher IL-6 and lower IL-10 expression than those with bone formation, while the expression of TNF-α did not show notable difference. Conclusion: The results of this study suggest an important role for IL-6 in modulating the efficacy of bone tissue engineering, which can affect osteogenic cells both positively and negatively.

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