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Measurement of top quark polarization in tt¯ lepton+jets final states
Abazov, V. M.,Abbott, B.,Acharya, B. S.,Adams, M.,Adams, T.,Agnew, J. P.,Alexeev, G. D.,Alkhazov, G.,Alton, A.,Askew, A.,Atkins, S.,Augsten, K.,Aushev, V.,Aushev, Y.,Avila, C.,Badaud, F.,Bagby, L.,Bal American Physical Society 2017 Physical Review D Vol.95 No.1
<P>We present a measurement of top quark polarization in t (t) over bar pair production in p (p) over bar collisions at root s = 1.96 TeV using data corresponding to 9.7 fb(-1) of integrated luminosity recorded with the D0 detector at the Fermilab Tevatron Collider. We consider final states containing a lepton and at least three jets. The polarization is measured through the distribution of lepton angles along three axes: the beam axis, the helicity axis, and the transverse axis normal to the t (t) over bar production plane. This is the first measurement of top quark polarization at the Tevatron using lepton + jet final states and the first measurement of the transverse polarization in t (t) over bar production. The observed distributions are consistent with standard model predictions of nearly no polarization.</P>
Measurement of Prompt D0 Meson Azimuthal Anisotropy in Pb-Pb Collisions at sNN=5.02 TeV
Sirunyan, A. M.,Tumasyan, A.,Adam, W.,Ambrogi, F.,Asilar, E.,Bergauer, T.,Brandstetter, J.,Brondolin, E.,Dragicevic, M.,Erö,, J.,Flechl, M.,Friedl, M.,Frü,hwirth, R.,Ghete, V. M.,Grossmann, J. American Physical Society 2018 Physical Review Letters Vol.120 No.20
<P>The prompt D-0 meson azimuthal anisotropy coefficients, v(2) and ?v(3), are measured at midrapidity ( |y| < 1.0) in Pb-Pb collisions at a center-of-mass energy root s(NN) = 5.02 TeV per nucleon pair with data collected by the CMS experiment. The measurement is performed in the transverse momentum (p(T)) range of 1 to 40 GeV/c, for central and midcentral collisions. The v(2) coefficient is found to be positive throughout the p(T) range studied. The first measurement of the prompt D-0 meson v(3) coefficient is performed, and values up to 0.07 are observed for p(T) around 4 GeV/c. Compared to measurements of charged particles, a similar p(T) dependence, but smaller magnitude for p(T) < 6 GeV/r, is found for prompt D-0 meson v(2) and v(3) coefficients. The results are consistent with the presence of collective motion of charm quarks at low p(r) and a path length dependence of charm quark energy loss at high p(r), thereby providing new constraints on the theoretical description of the interactions between charm quarks and the quark-gluon plasma.</P>
Hervouet, C,Luci, C,Bekri, S,Juhel, T,Bihl, F,Braud, V M,Czerkinsky, C,Anjuè,re, F Society for Mucosal Immunology 2014 Mucosal immunology Vol.7 No.2
Effector T cells are described to be primed in the lymph nodes draining the site of immunization and to recirculate to effector sites. Sublingual immunization generates effector T cells able to disseminate to the genital tract. Herein, we report an alternative mechanism that involves the recirculation of antigen-bearing dendritic cells (DCs) in remote lymphoid organs to prime T cells. Sublingual immunization with a muco-adhesive model antigen unable to diffuse through lymphatic or blood vessels induced genital CD8 T cells. The sublingual draining lymph nodes were not mandatory to generate these lymphocytes, and antigen-bearing DCs from distant lymph nodes and spleen were able to prime specific CD8 T cells in a time- and dose-dependent manner. This study demonstrates, for the first time, that antigen-bearing DCs originating from the site of immunization recirculate to distant lymphoid organs and provides insights into the mechanism of distant CD8 T-cell generation by sublingual immunization.
Sirunyan, A. M.,Tumasyan, A.,Adam, W.,Ambrogi, F.,Asilar, E.,Bergauer, T.,Brandstetter, J.,Brondolin, E.,Dragicevic, M.,Erö,, J.,Flechl, M.,Friedl, M.,Frü,hwirth, R.,Ghete, V. M.,Grossmann, J. Springer-Verlag 2017 Journal of high energy physics Vol.2017 No.11
<P>A search for pair production of massive vector-like T and B quarks in proton-proton collisions at root s = 13 TeV is presented. The data set was collected in 2015 by the CMS experiment at the LHC and corresponds to an integrated luminosity of up to 2.6 fb(-1). The T and B quarks are assumed to decay through three possible channels into a heavy boson (either a W, Z or Higgs boson) and a third generation quark. This search is performed in final states with one charged lepton and several jets, exploiting techniques to identify W or Higgs bosons decaying hadronically with large transverse momenta. No excess over the predicted standard model background is observed. Upper limits at 95% confidence level on the T quark pair production cross section are set that exclude T quark masses below 860 GeV in the singlet, and below 830 GeV in the doublet branching fraction scenario. For other branching fraction combinations with B (T -> tH) + B(T -> bW) >= 0.4, lower limits on the T quark range from 790 to 940 GeV. Limits are also set on pair production of singlet vector-like B quarks, which can be excluded up to a mass of 730 GeV. The techniques showcased here for understanding highly-boosted final states are important as the sensitivity to new particles is extended to higher masses.</P>
Juan Garona,Natasha T. Sobol,Marina Pifano,Valeria I. Segatori,Daniel E. Gomez,Giselle V. Ripoll,Daniel F. Alonso 대한암학회 2019 Cancer Research and Treatment Vol.51 No.2
Purpose Control of metastatic spread of colorectal cancer (CRC) remains as a major therapeutic challenge. [V4Q5]dDAVP is a vasopressin peptide analog with previously reported anticancer activity against carcinoma tumors. By acting as a selective agonist of arginine vasopressin type 2 membrane receptor (AVPR2) present in endothelial and tumor cells, [V4Q5]dDAVP is able to impair tumor aggressiveness and distant spread. Our aim was to evaluate the potential therapeutic benefits of [V4Q5]dDAVP on highly aggressive CRC disease using experimental models with translational relevance. Materials and Methods Murine CT-26 and human Colo-205 AVPR2-expressing CRC cell lines were used to test the preclinical efficacy of [V4Q5]dDAVP, both in vitro and in vivo. Results In syngeneic mice surgically implanted with CT-26 cells in the spleen, sustained intravenous treatment with [V4Q5]dDAVP (0.3 g/kg) dramatically impaired metastatic progression to liver without overt signs of toxicity, and also reduced experimental lung colonization. The compound inhibited in vivo angiogenesis driven by Colo-205 cells in athymic mice, as well as in vitro endothelial cell migration and capillary tube formation. [V4Q5]dDAVP exerted AVPR2-dependent cytostatic activity in vitro (IC50 1.08 M) and addition to 5-fluorouracil resulted in synergistic antiproliferative effects both in CT-26 and Colo-205 cells. Conclusion The present preclinical study establishes for the first time the efficacy of [V4Q5]dDAVP on CRC. These encouraging results suggest that the novel second generation vasopressin analog could be used for the management of aggressive CRC as an adjuvant agent during surgery or to complement standard chemotherapy, limiting tumor angiogenesis and metastasis and thus protecting the patient from CRC recurrence.
Induced quadrupolar singlet ground state of praseodymium in a modulated pyrochlore
van Duijn, J.,Kim, K. H.,Hur, N.,Ruiz-Bustos, R.,Adroja, D. T.,Bridges, F.,Daoud-Aladine, A.,Fernandez-Alonso, F.,Wen, J. J.,Kearney, V.,Huang, Q. Z.,Cheong, S.-W.,Perring, T. G.,Broholm, C. American Physical Society 2017 Physical Review B Vol.96 No.9
<P>The complex structure and magnetism of Pr2-xBixRu2O7 was investigated by neutron scattering and extended x-ray absorption fine structure. Pr has an approximate doublet ground state and the first excited state is a singlet. While the B-site (Ru) is well ordered throughout, this is not the case for the A-site (Pr/Bi). A broadened distribution for the Pr-O-2 bond length at low temperature indicates the Pr environment varies from site to site even for x = 0. The environment about the Bi site is highly disordered ostensibly due to the 6s lone pairs on Bi3+. Correspondingly, we find that the non-Kramers doublet ground-state degeneracy, otherwise anticipated for Pr in the pyrochlore structure, is lifted so as to produce a quadrupolar singlet ground statewith a spatially varying energy gap. For x = 0, below TN, the Ru sublattice orders antiferromagnetically, with propagation vector k = (0,0,0) as forY(2)Ru(2)O(7). No ordering associated with the Pr sublattice is observed down to 100 mK. The low-energy magnetic response of Pr2-xBixRu2O7 features a broad spectrum of magnetic excitations associated with inhomogeneous splitting of the Pr quasidoublet ground state. For x = 0 (x = 0.97), the spectrum is temperature dependent (independent). It appears disorder associated with Bi alloying enhances the inhomogeneous Pr crystal-field level splitting so that intersite interactions become irrelevant for x = 0.97. The structural complexity for the A-site may be reflected in the hysteretic uniform magnetization of B-site ruthenium in the Neel phase.</P>
Kostov, V. B.,McCullough, P. R.,Hinse, T. C.,Tsvetanov, Z. I.,Hé,brard, G.,Dí,az, R. F.,Deleuil, M.,Valenti, J. A. IOP Publishing 2013 The Astrophysical journal Vol.770 No.1
<P>We report the discovery of a transiting, gas giant circumbinary planet orbiting the eclipsing binary KIC 4862625 and describe our independent discovery of the two transiting planets orbiting Kepler-47. We describe a simple and semi-automated procedure for identifying individual transits in light curves and present our follow-up measurements of the two circumbinary systems. For the KIC 4862625 system, the 0.52 +/- 0.018 R-Jupiter radius planet revolves every similar to 138 days and occults the 1.47 +/- 0.08 M-circle dot, 1.7 +/- 0.06 R-circle dot F8 IV primary star producing aperiodic transits of variable durations commensurate with the configuration of the eclipsing binary star. Our best-fit model indicates the orbit has a semi-major axis of 0.64 AU and is slightly eccentric, e = 0.1. For the Kepler-47 system, we confirm the results of Orosz et al. Modulations in the radial velocity of KIC 4862625A are measured both spectroscopically and photometrically, i.e., via Doppler boosting, and produce similar results.</P>
Lutz, M.F.M.,Lange, J.S.,Pennington, M.,Bettoni, D.,Brambilla, N.,Crede, V.,Eidelman, S.,Gillitzer, A.,Gradl, W.,Lang, C.B.,Metag, V.,Nakano, T.,Nieves, J.,Neubert, S.,Oka, M.,Olsen, S.L.,Pappagallo, North Holland Pub. Co 2016 Nuclear physics. A Vol.948 No.-
<P>We report on the EMMI Rapid Reaction Task Force meeting 'Resonances in QCD', which took place at GSI October 12-14,2015. A group of 26 people met to discuss the physics of resonances in QCD. The aim of the meeting was defined by the following three key questions: What is needed to understand the physics of resonances in QCD? Where does QCD lead us to expect resonances with exotic quantum numbers? What experimental efforts are required to arrive at a coherent picture? For light mesons and baryons only those with up, down and strange quark content were considered. For heavy-light and heavy-heavy meson systems, those with charm quarks were the focus. This document summarizes the discussions by the participants, which in turn led to the coherent conclusions we present here. (C) 2016 Elsevier B.V. All rights reserved.</P>
Measurement of the decaysBs0→J/ψϕ(1020),Bs0→J/ψf2′(1525)andBs0→J/ψK+K−at Belle
Thorne, F.,Schwanda, C.,Adachi, I.,Aihara, H.,Asner, D. M.,Aulchenko, V.,Aushev, T.,Bakich, A. M.,Bala, A.,Bhuyan, B.,Bonvicini, G.,Brač,ko, M.,Chang, M. -C.,Chekelian, V.,Chen, A.,Cheon, B. G.,C American Physical Society 2013 PHYSICAL REVIEW D - Vol.88 No.11
Search for theX(4140)state inB+→J/ψϕK+decays with the D0 detector
Abazov, V. M.,Abbott, B.,Acharya, B. S.,Adams, M.,Adams, T.,Agnew, J. P.,Alexeev, G. D.,Alkhazov, G.,Alton, A.,Askew, A.,Atkins, S.,Augsten, K.,Avila, C.,Badaud, F.,Bagby, L.,Baldin, B.,Bandurin, D. V American Physical Society 2014 PHYSICAL REVIEW D - Vol.89 No.1
<P>We investigate the decay B+ -> J/psi phi K+ in a search for the X(4140) state, a narrow threshold resonance in the J/psi phi system. The data sample corresponds to an integrated luminosity of 10.4 fb(-1) of p (p) over bar collisions at root s = 1.96 TeV collected by the D0 experiment at the Fermilab Tevatron collider. We observe a mass peak with a statistical significance of 3.1 standard deviations and measure its invariant mass to be M = 4159.0 +/- 4.3(stat) +/- 6.6(syst) MeV and its width to be Gamma = 19.9 +/- 12.6(stat)(-8.0)(+3.0)(syst) MeV.</P>