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      • KCI등재

        Life history responses of the cabbage beetle Colaphellus bowringi to temperature change

        Jian‐Jun Tang,Hai-Min HE,Ting GENG,Shu FU,Fang-Sen XUE 한국곤충학회 2016 Entomological Research Vol.46 No.6

        Temperature is considered one of the most important mediators of phenotypic plasticity in ectotherms. Here, we investigated life history traits of the cabbage beetle, Colaphellus bowringi Baly (Coleoptera: Chrysomelidae), at a wide range of temperatures (16, 19, 22, 24, 26 and 28°C). The larval and pupal times were significantly decreased with increasing rearing temperature and growth rate was positively correlated with temperature. However, the relationship between body size and rearing temperature in C. bowringi did not follow the temperature–size rule; both males and females reached the highest body weight at 19°C. Females were significantly larger than males at all temperatures. Male pupae lost significantly more weight at metamorphosis compared to females. However, diapausing males gained significantly higher weight after feeding compared to diapausing females at higher temperatures of 22, 24, 26 and 28°C. Body weight tended to decrease with increasing rearing temperature, whereas sexual size dimorphism (SSD) tended to increase with increasing rearing temperature; thus, Rensch's rule is upheld. The degree to which SSD changed with temperature varied with different development stages. SSD was lowest in pupae, highest in newly emerged adults and intermediate in diapausing adults.

      • Comparison of Serum Tumor Associated Material (TAM) with Conventional Biomarkers in Cancer Patients

        Shu, Jian,Li, Cheng-Guang,Liu, Yang-Chen,Yan, Xiao-Chun,Xu, Xu,Huang, Xin-En,Cao, Jie,Li, Ying,Lu, Yan-Yan,Wu, Xue-Yan,Liu, Jin,Xiang, Jin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

        Objective: To compare expression level of serum tumor associated materials (TAM) with several conventional serum tumor biomarkers, eg., carcinoembryonic antigen (CEA), carbohydrate antigen19-9 (CA19-9), carbohydrate antigen 15-3 (CA15-3), alpha-fetoprotein(AFP), in selected solid tumors. Methods: Patients diagnosed histologically or cytologically with liver, breast, esophageal, gastric, colorectal or pancreatic cancers were enrolled into this study. After diagnosis, the level of TAM was determined by chemical colorimetry, and levels of conventional tumor markers was measured by chemiluminescence methods. Results: A total of 560 patients were enrolled into this study. No statistically significant difference was detected in TAM and the above mentioned tumor biomarkers in terms of their positivity and negativity ( P>0. 05). Conclusions: Detection of TAM in liver, breast, esophageal, gastric, colorectal, and pancreatic cancer patients demonstrates a good accordance with CEA, CA199, CA153, and AFP, thus suggesting that further study is warranted to verify whether TAM could be a surrogate for these conventional biomarkers.

      • KCI등재

        바이오닉과 색채 디자인의 융합 연구

        서건연(Shu, Jian Yan),이성원(Lee, Sung Won) 한국전시산업융합연구원 2021 한국과학예술융합학회 Vol.39 No.1

        본 연구는 제품 색채 디자인의 혁신적인 방법에 관한 연구에서 시작되었다. 본 연구의 목적은 바이오닉과 색채 디자인의 융합에 관한 연구를 통해 색채 바이오닉 디자인 모형을 모색하는 데에 있다. 생물체의 색채 조직 구조와 색채심리 감정의 각도에서 바이오닉 디자인하고 색채 바이오닉 결과의 정확도에 영향을 미치는 요소를 확인하여 제품의 혁신적인 디자인과 색채 디자인에 참고할 만한 자료를 제공하고자 한다. 따라서, 기존의 선행 된 이론 연구와 응용 실례를 제시하고 색채 바이오닉 디자인의 모형을 구축했다. 그다음 설문 조사를 통해 색채 바이오닉 결과의 정확도에 영향을 미치는 요소를 확인하였다. 연구 결과 및 내용은 다음과 같다. 첫째, 조사 결과 색채 바이오닉 디자인의 과정에서 색채 원형(단색, 양색, 다색), 색채 면적 비례, 색채의 위치(위는 가볍고 아래는 무겁다, 위아래는 균일하다, 위는 무겁고 아래는 가볍다)에 대한 반영은 색채 바이오닉의 정확도에 영향을 미칠 수 있다. 둘째, 이용자의 속성(성별, 색채기초 유 무, 색채 바이오닉에 대한 이해도)은 색채 원형, 색채 면적 비례, 색채 위치에 대한 주관적인 감각과 바이오닉 디자인 결과의 정확도에 영향을 미칠 수 있다. 본 연구의 연구 결과를 바탕으로 더욱더 자연스러운 제품 색채를 디자인할 수 있기를 바라고 향후 디자인에서 생물 시스템에서의 우수한 색채 기능을 활용하여 제품 색채 디자인의 색 공간을 넓히는 데 도움이 되길 기대한다. This study began with a study on an innovative method of product color design. The purpose of this study is to explore a color bionic design model through research on the fusion of bionic and color design. We aim to provide reference material for innovative design and color design of products by designing bionics from the angle of color organizational structure and color psychology of living organisms, and identifying factors that influence the accuracy of color bionic results. Therefore, the previous theoretical research and application examples were presented and a model of color bionic design was constructed. Then, through a questionnaire survey, factors affecting the accuracy of the color bionic results were identified. The results and contents of the study are as follows. First, as a result of the investigation, in the process of color bionic design, reflection of the color circle (monochrome, bicolor, multicolor), color area proportion, and color position (the top is light, the bottom is heavy, the top and bottom are uniform, the top is heavy and the bottom is light). Silver can affect the accuracy of the color bionic. Second, the user"s attributes (gender, presence or absence of color basics, understanding of color bionics) can affect the color prototype, color area proportion, subjective sense of color position, and the accuracy of the bionic design result. We hope to be able to design more natural product colors based on the research results of this study, and hope that it will help to widen the color space of product color design by utilizing excellent color functions in biological systems in future designs.

      • KCI등재

        Remarkably efficient hydrolysis of cinnamaldehyde to natural benzaldehyde in amino acid ionic liquids

        Duan-Jian Tao,Xiang-Shu Chen,Shu Xu,Feng-Feng Chen,Yan Zhou,Xin Zhao,Li-Li Yu,Kuan Huang 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.12

        The hydrolysis of cinnamaldehyde to natural benzaldehyde was investigated systematically using tetramethylammonium- based amino acid ionic liquids as homogeneous catalysts. The results indicated that tetramethylammonium prolinate ([N1111][Pro]) can be a powerful catalyst for the highly efficient hydrolysis of cinnamaldehyde, in which natural benzaldehyde was obtained with almost 94% yield and over 99% selectivity in 1 h. Moreover, kinetic study showed that compared with other catalysts, the catalytic system of [N1111][Pro] has a lower activation energy of 38.30 kJ·mol−1 in the hydrolysis reaction, indicating superior catalytic performance of [N1111][Pro]. Quantum-mechanical calculations further manifested that such high performance originates from the cooperative catalysis of the secondary amino and carboxyl group in the anion [Pro].

      • SCIESCOPUSKCI등재

        Protective Effect of Magnolol on TBHP-Induced Injury in H460 Cells Partially via a p53 Dependent Mechanism

        Gao, Jian-Mei,Ying, Xi-Xiang,Wang, Shu-Peng,Li, Jian-Chun,Li, Hai-Bo 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.7

        The aim is to investigate the effect of Magnolol preserved H460 cells from an oxidative agent tert-butylhydroperoxide (TBHP)-induced cell death. Magnolol augmented cell survival ratio after TBHP challenged. The protective action of this drug was more efficacious than that of N-acetylcysteine (NAC) which is a putative antioxidant. DNA damage, detected by the comet assay, was diminished after treatment of Magnolol. The cells viability decreased after treatment with 0.15 mM TBHP for 24 h, accompanied by inducing apoptotic death of the cells. Cytotoxicity and apoptosis induced by TBHP were significantly inhibited or attenuated after pretreatment with $20\;{\mu}M$ Magnolol. Magnolol contributes to the cells survival through downregulated the p53 phosphorylation and PTEN expression, and upregulated Akt phosphorylation. Taken together, Magnolol was effective against DNA single strand breaks (SSB) formation, cytotoxicity and lipid peroxidation induced by TBHP, and its effects on p53 phosphorlation, PTEN and Akt phosphorylation were due to its antioxidative function, and partially via a p53 dependent mechanism in this protective effects.

      • KCI등재

        한·중·일 전통 색채 체계 표준색 특성 비교연구

        서건연(Shu, Jian Yan),이성원(Lee, Sung Won) 한국디자인리서치학회 2020 한국디자인리서치 Vol.5 No.2

        한·중·일 세 나라의 전통 색채 체계 간의 유사점과 차이점, 그리고 각 나라 전통 색채 이론 형성 간의 연관성을 비교·분석하는 데에 그 목적이 있다. 전통 색채의 색값을 추출하여 NCS 시스템에 도입해 색채의 색상, 명도, 채도를 비교 한·중·일 세 나라의 전통 색채 체계의 유사점과 차이점을 분석하였다. 이와 동시에 전통 색채 이론 형성을 비교하였다. 색상의 경우 빨강 색조, 노랑 색조, 파랑 색조와 녹 색조는 세 나라에서 차지하는 비율이 모두 15% 이상이었다. 한국의 주된 색조는 빨강 색조이고 중국과 일본의 주된 색조는 노랑 색조이다. 명도의 경우, 한국은 중간 명도 색채가 차지하는 비율이 가장 높고 중국과 일본은 고명도 색채가 차지하는 비율이 가장 높다. 채도의 경우, 한국은 고채도 색채가 차지하는 비율이 가장 높고, 중국에서는 중채도 색채가 차지하는 비율이 가장 높으며 일본에서는 저채도 색채가 차지하는 비율이 가장 높다. 이들 전통 색채 이론의 형성은 모두 중국의 음양오행설의 영향을 받았고 세 나라는 모두 등급별 복장 색상 사용의 제한을 통해 등급을 구분하지만, 실제 응용에서 서로 다른 색상 특징을 발전시켰다. 연구의 결과로 전통 색채 체계의 표준색채 간의 비교를 통해 동아시아 전통 색채의 다양성을 보았다. 이 연구를 통해 전통 색채의 응용과 발전을 추진하고 각국 간의 색채 문화 연구와 다양한 국가 간의 문화교류에 새로운 아이디어와 디자인 패턴을 제공하길 기대한다. Aiming at researching for the relations among the three traditional color systems of Korea, China and Japan, including their similarities and differences in terms of color characteristics as well as the connections between their theory formations. Creating color samples based on standard color values of traditional color system, then analyzing its tone, brightness and saturation by NCS to gain color characteristics as well as color similarities and differences of the traditional color system of Korea, China and Japan, and at the same time, to compare their theory formation. Regarding tone, the total percentage of red, yellow, blue and green are all above 15% in three countries. The main color in Korea is red, while in China and Japan the main color is yellow. Concerning brightness, Medium-brightness color is mainstream in Korea, while in China and Japan, high-brightness color is dominant. In terms of saturation, In Korea, high saturation colors are prevailing but in China, medium saturation color is dominant and low saturation color is more prevalent in Japan. Their theory formation all affected by Chinese Yin and Yang and the theory of five elements. These three countries all identify different stratum by limiting the usage of colors on their costume, but varied color characteristics are developed in practice application. As a result of the study, the diversity of traditional Asian colors was examined through comparison between standard colors of traditional color systems. Through this study, we hope to promote the application and development of traditional colors, and to provide new ideas and design patterns for research on color culture between countries and cultural exchange between various countries.

      • KCI등재

        The white gene in Nilaparvata lugens and its expression pattern under two different survival stresses

        Shu Hua Liu,Bao Jun Yang,Ai YingWang,Ju Luo,Jian Tang 한국응용곤충학회 2018 Journal of Asia-Pacific Entomology Vol.21 No.2

        The brown planthopper (BPH), Nilaparvata lugens (Stål), is a serious pest of rice. Chemical control and pestresistant rice breeding are always two major management strategies of BPH. In order to keep effective control, understanding the detoxification mechanism of this insect pest appears to be high important. In addition to be an eye pigment transporter, White protein is also important for its non-eye roles, such as a potential target for insecticides and Bt toxin. In this study, we characterized the full-length white orthologues gene in N. lugens (Nlwhite). NlWhite, the deduced protein of Nlwhite, has feature motifs of the eye pigment transporter. Knocking down Nlwhite transcript, the compound eye color partially changed to white. Nlwhite can be detected in all developmental stages and body parts, indicating that it is not a developmental or tissue-specific expression gene. The expression levels of Nlwhite were all significantly upregulated in both pymetrozine-selection and Mudgoselection BPH strains, which were selected for several generations. These results indicated that NlWhite participated in the detoxification not only for the exogenous insecticides but also for the endogenous toxic substance.

      • KCI등재

        Knockdown of an ABC transporter leads to bright red eyes in the brown planthopper, Nilaparvata lugens (Stål) (Hemiptera: Delphacidae)

        Shu Hua Liu,Ai YingWang,Bao Jun Yang,Ju Luo,Jian Tang 한국응용곤충학회 2017 Journal of Asia-Pacific Entomology Vol.20 No.2

        Compound eye color is an important biological character of insects,which is determined by the nature of eye pigments. Ommochrome is the solely source of eye color for some insects, while pteridines is also needed for the other insect species. However, little is known about the eye pigment composition for any planthopper. Scarlet is an ABC (ATP-binding cassette) transporter protein, which functions as the transmembrane transporter for ommochrome precursor. The failure of Scarlet function can cause bright red or white eyes in different species, which depending on the nature of eye pigments. Here, we identified a scarlet ortholog gene (Nlst) from the brown planthopper (BPH), Nilaparvata lugens, which is a destructive insect pest of rice. Nlst is the first characterized eye pigment transporter gene from Hemipteran. NlSt, the protein deduced from Nlst, has an open reading frame (ORF) of 629 amino acidswith the two sequence logos for eye pigment transporters. Expression profile revealed that Nlst expressed at all development stages and had the highest transcript level in head. Knockdown the Nlst transcript, the wild-type eye color partially changed to bright red, while not to white. Meantime, the ommochrome level in heads reduced to 73.4%. These results suggested that the eye coloration of BPH needs both ommochrome and pteridines pigments. Because nymphal RNAi with Nlst leading to a clearly distinguished phenotype from the control individuals, Nlst maybe a suitable genetic marker to exploit embryonic RNAi technique in this insect pest.

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