골유착성 임플랜트를 중간지대치로 사용한 고정성 보철물의 응력분석

박상수,방몽숙 전남대학교 치과대학 1992 전남치대논문집 Vol.4 No.1

The purpose of this study was to analyze the stress distribution of the natural teeth, the implant, the prosthesis and the supporting tissue according to the types of implant and connection modality in the five-unit fixed partial denture with a implant pier abutment. A Two dimensional stress analysis model was constructed to represent a mandible missing the first and second premolars and first molar. The model contained a canine and second molar as abutment teeth and implant pier abutments with and without stress-absorbing element. Finite element models were created and analyzed using software ANSYS 4.4A for IBM 32bit personal computer. The results obtained were as follows; 1. Implant group, compared to the natural teeth group, showed a maximum principal stress at the superior portion of implants and a stress concentration at the neck and end portion. 2. Maximum principal stress and maximum Von Mises stress were always lower in the case of rigid connection than nonrigid connection. 3. A cylinder type implant with stress absorbing element and screw type implant were generally similar in the stress distribution pattern. 4. A screw type implant, compared to the cylinder type implant, showed a relatively higher stress concentration at both neck and end portion of it. 5. Load B cases showed higher stress concentration on the posterior abutments in the case of nonrigid connector than rigid connector. 6. A maximum displacement was always lower in the case of rigid connection than nonrigid connection. These results suggest that osseointegrated implant can be used as an intermediate abutment.

작잠의 5령 유충의 조직 및 알의 수용성 단백질의 전기영동적 분석비교

문영천,김종훈,이상몽 밀양대학교 농업기술개발연구소 2000 農業技術開發硏究所報 Vol.4 No.1

Antheraea pernyi water soluble proteins in egg, hemolymph, fat-body, mid-gut, integument, middle silk gland and posterior silk gland were examined by 7.5% Native-PAGE and 2D-electrophoresis. From 7.5% Native-PAGE, each tissues and egg showed their own characteristic electrophoretic band patterns. Also, in 2D electrophoresis of the fat-body proteins, 70∼40KDa polypeptide spots were main polypepticles.

키토산을 첨가한 의치상 재료의 세균 부착에 관한 연구

정승환,방몽숙 전남대학교 치과대학 2000 전남치대논문집 Vol.12 No.1

The purpose of this study were to evaluate the adherence of bacteria on various denture base resin materials and effects of chitosan, added to denture base materials on bacterial adherence. PMMA denture base resin such as heat-cured Vertex-RS, self-cured Vertex-SC and 4-META denture base resin such as heat-cured Meta-Dent, self-cured Meta-Fast were used in this study. Samples were divided into two groups : the denture base resin with chitosan, without chitosan. Streptococcus mutans and Lactobacillus casei were used in this study. The surface of samples was observed by SEM. When chitosan was added to M17 and MRS broth, viable cell count of bacteria was reduced. Viable cell count of Streptococcus mutans on the samples decreased as follows: Meta-Dent, Vertex-SC, Meta-Fast, Vertex-RS. Viable cell count of Lactobacillus casei on the samples decreased as follows: Vertex-RS, Meta-Dent, Meta-Fast, Vertex-SC. The resin with chitosan showed lower adherence of bacteria than without chitosan. The images of SEM showed that the surface of the resin with chitosan was rougher than without chitosan. These results showed that the denture base resin materials with chitosan have rougher surface than without chitosan, but less bacteria adhered on them.

연마 방법에 따른 Cerec block의 표면 거칠기 비교

김성광,박몽숙 전남대학교 치과대학 1995 전남치대논문집 Vol.7 No.1

This study was performed to investigate the surface roughness of the Cerec Vita Mark Ⅱ block polished by various polishing techniques, compare with that of the Vintage enamel porcelain glazed by high temperature glazing technique. All of the Cerec specimen were finished with sequential use of high speed diamond burs(grit 45, 30 and 15㎛). The groups were divided into 5 groups : Group Ⅰ : Cerec Vita Mark Ⅱ block specimens polished with Sof-lex discs. Group Ⅱ : Cerec Vita Mark Ⅱ block specimens polished with Two Striper MPS. Group Ⅲ : Cerec Vita Mark Ⅱ block specimens polished with Enhance. Group Ⅳ : Cerec Vita Mark Ⅱ block specimens polished with Porcelain laminate polishing FG kit. Group Ⅴ : Vintage enamel porcelain glazed by high temperature glazing technique. Each group was consisted of 10 specimens. The surfaces produced wereexamined quantitatively using a laser specular reflectance machine(PertheJSM-5400, JEOL, Japan). The results were as follows : 1. The arithmetic mean roughness value(Ra) in groups 1, 2, 3 and 4 was higher than that of group 5. There was statistically significant difference(P<0.05). 2. The arithmetic mean roughness value(Ra) decreased in the following orders : group 1, group 2, group 4, group 3 and there was no statistically significant difference between group 1 and group 2, group 3 and group 4. There was statistically significant difference among group 1, 2, and group 3, 4 and group 5(P<0.05). 3. The maximum individual peak-to-valley-height(Rmax) decreased in the following orders : group 2, group 1, group 4, group 3, group 5 and there was no statistically significant difference between group 1 and 2, group 1 and group 4, group 3 and group 5. There was statistically significant difference among group 1, 2, and group 1, 4 and group 3, 5(P<0.05). 4. The treated surfaces of group 5 had smoother surface than that of groups 1, 2, 3, 4 with SEM.

KAL기 추락에 의한 대량재해의 개인식별

강신몽,이원태,고영창,최상규,김윤희,이홍석,서재관,윤중진,이혜경,최득린,김종열,윤창육,변명식,이장홍 大韓法醫學會 1991 대한법의학회지 Vol.15 No.2

Individual identification is an important part in medicolegal field especially in mass disaster. At July, 27, 1989, KAL KE-803 was crashed on landing at Tripoli International Airport, Liba. The plane was caught in fire and sixty eight Koreans were sacrified. The majority of victims were severely charred and injured. The authors examed all dead bodies and successfully identified all the cases through visual, anthropological, odontological, radiological and pathological methods including fingerprint and blood typing.

의료관계 해부 감정예의 분석적 연구(I) : 1990년 국립과학수사연구소 감정예

姜信夢,李垣兌,李漢榮,尹順雄,全基悳,金相鉉,徐在冠,尹重鎭 大韓法醫學會 1991 대한법의학회지 Vol.15 No.2

A study of 118 autopsy cases associated with medical care in 1990 was present according to the medical department, the mode of treatment and the cause of death. The Pediatrics showed the highest rate (25.4%), followed by the Obstetrics & Gynecology (22.9%), and Internal medicine (20.2%). According to the mode of treatment, medical accidents during operation and anesthesia were 29 cases (24.6%) with highest rate in Obstetrics & Gynecology (13 cases), 38 cases (32.2%) were during medication and/or injection with highest rate in Internal Medicine (18 cases), and 51 cases (43.2%) were during general medical practice with highest rate in pediatrics (19 cases). The most prevalent cause of death was the disease of respiratory system (34.9%, 30 cases) and the diseases of cardiovascular and urogenital system accounted for 31.4% and 11.6% respectively. The main cause of death in Internal medicine was the disease of cardiovascular system (11/24 cases), the respiratory system in pediatrics (15/30 cases) and the disease of urogenital system in Obstetrics & Gynecology (9/27 cases. ) Asphyxial deaths were 7 cases and the death due to adverse drug reaction accounted for 10 cases.

광주기에 따른 누에번데기 동충하초의 생장양태

이은하,이상몽 밀양대학교 농업기술개발연구소 2000 農業技術開發硏究所報 Vol.4 No.1

Host-pathogen relationship and comparison of inoculation methods of the six entomopathogenic fungi strains (three of Paecilomyces japonica, J2, C24O, C66O; two of Cordyceps militsris, C18, C738; one of Cordyceps scarabaeiclola, C252) to the silkworm, Bombyx mori were investigated. 1.All the six entomopathogenic fungi tested in the present study infected their host, silkworm, Bombyx mori, through the larval or the pupal stages. 2.Time of inoculation (or germination) on the host silkworm was at the 5th larval or pupal stages for all the fungi. 3.The Paecilomyces strains, J2, C24O, C66O showed higher infection ratio than the Cordyceps militaris C18, C738 and Cordyceps scarabaeicola C252. 4.The degree of infection level on the silkworm varied according to inoculation methods used. 5.Time required for fruiting-body formation was longer in the method "Spray" than in the method "injection or immersion"

Purification and Partial Characterization of the Storage Protein-like Protein from the 5th Instar Larval Haemolymph of the Chinese Oak Silkworm, Antheraea pernyi .

Park, Nam Suk,Lee, Sang Mong,Moon, Jae Yu,Seong, Su Il 한국잠사학회 1999 한국잠사곤충학회지 Vol.41 No.2

The storage protein-like protein has been purified from the 5th instar larval haemolymph of the Chinese oak silkworm, Antheraea pernyi, and the preparation was shown to be homogeneous by 7.5% nativePAGE. The molecule was consisted of a single Submit with a molecular weight of 80K, but the number of the subunits was not determined. The protein was defined as glycoprotein by Schiffl's reagent stainting. Rabbit antibody prepared against the purified protein crossreacted with the 5th instar larval haemolymph protein of Antheraea pernyi and Anteraea yamamai, but not with those of Bombyx mori and Bombyx mandarina.

Clinical characteristics and recurrence-related factors of medication-related osteonecrosis of the jaw

Mong Hun Kang,Dong Keon Lee,Chang Woo Kim,In Seok Song,Sang Ho Jun 대한구강악안면외과학회 2018 대한구강악안면외과학회지 Vol.44 No.5

Objectives: The purpose of this study was to investigate the demographic and clinical characteristics of patients with medication-related osteonecrosis of the jaw (MRONJ) and to elucidate factors affecting recurrence in surgical treatment. Materials and Methods: A total of 51 patients who were diagnosed with MRONJ were analyzed according to demographic and clinical features and treatment results through a retrospective chart review from 2013 to 2017 in the Department of Oral and Maxillofacial Surgery, Korea University Anam Hospital, Seoul in Korea. Results: Alendronate composed the majority of medication doses (55.6%), followed by ibandronate (20.0%), risedronate (15.6%), and zoledronate (6.7%). Forty patients (88.9%) were given oral medication, and five patients (11.1%) were intravenously treated, and the mean duration of medication use was 61.1±42.9 months. A total of 10 patients (22.2%) had a drug holiday before MRONJ-induced dental treatment lasting an average of 6.8±7.0 months. MRONJ occurred 2.7 times more in the mandible, with 41 cases (73.2%) occurring in the mandible and 15 cases (26.8%) occurring in the maxilla, and the prevalence of affected posterior parts (premolar-molar) was six times greater than that of the anterior parts (incisor-canine) (48 cases vs 8 cases, 85.7% vs 14.3%). The most common dental cause of MRONJ was tooth extraction (69.6%). Regarding recurrence, there was no statistical difference in recurrence rate according to either site or stage. However, recurrence occurred in 4 out of 34 cases (11.8%) in the primary closure group and 9 out of 20 cases (45.0%) in the secondary healing group, and there was a statistical difference with respect to closure technique. Conclusion: The identified risk factors in patients taking bone resorption inhibitors can aid dental clinicians in ensuring prevention and proper treatment of MRONJ.

The predictors of sustained virological response with sofosbuvir and ribavirin in patients with chronic hepatitis C genotype 2

( Sung Yong Han ),( Hyun Young Woo ),( Jeong Heo ),( Sang Gyu Park ),( Sung Ik Pyeon ),( Young Joo Park ),( Dong Uk Kim ),( Gwang Ha Kim ),( Hyung Hoi Kim ),( Geun Am Song ),( Mong Cho ) 대한내과학회 2021 The Korean Journal of Internal Medicine Vol.36 No.3

Background/Aims: Real-world, clinical practice data are lacking about sofosbuvir/ ribavirin (SOF/RBV) treatment of Korean patients with hepatitis C virus genotype 2 (HCV GT2) infection. This study investigated the efficacy and safety of SOF/RBV in Korean patients with HCV GT2 infection and clinical factors predicting sustained virological response 12 weeks (SVR12) after the end of SOF/RBV treatment. Methods: A total of 181 patients with HCV GT2 with/without cirrhosis were treated with SOF/RBV for 16/12 weeks. Rapid virological response (RVR) was defined as non-detectable HCV RNA at 4 weeks. Results: The RVR rate was 80.7% (146/181), the end of treatment response rate was 97.8% (177/181) and the SVR12 rate was 92.8% (168/181). Of eight patients with relapse, four did not achieve RVR. Three patients had a history of hepatocellular carcinoma (HCC). Multivariable analysis showed that RVR (p = 0.015) and no previous history of HCC (p = 0.007) were associated with SVR12. Factors significantly contributing to RVR included cirrhosis, creatinine concentration, and pre-treatment HCV RNA level. SVR12 rate was significantly higher in RVR (+) than RVR (-) patients (95.2% vs. 82.9%, p = 0.011) and also significantly higher in patients without than with a history of HCC (94.1% vs. 72.7%, p = 0.008). During treatment, 80/181 patients (44.2%) experienced mild to moderate adverse events, with 32 (17.7%) requiring RBV dose reductions due to anemia. Conclusions: SOF/RBV treatment was effective and tolerable in HCV GT2 patients. RVR and no previous history of HCC were positive predictors of SVR12.