Upwind Finite Element Model for Suspended Sediment Transport

Noh,Joon-Woo 한국습지학회 2003 한국습지학회지 Vol.5 No.1

Rat의 복강에 삽입한 Fluorouracil-Polyglycolic acid 제형의 Fluorouracil 용출에 관한 연구

노승무,정경수,오정연,김진향,양준묵,강대영,송규상,최정목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1

A common form of relapse in adenocarcinoma of the stomach is intraperitoneal dissemination, in fact, among gastric adenocarcinoma patients who have undergone surgery intended to cure, approximately 50% of the patients develope initial recurrence in the peritoneal cavity regardless of the anatomic site of the primary tumor within the stomach. The efficacy of systemic postoperative chemotherapy to prevent peritoneal recurrence of gastrric adcnocarcinoma is not satisfactory. There is still a great need for improved therapeutic strategies on the disseminated microscopic disease and small miliary nodules remaining on the peritoneal surface or lymphatics after operation. The authers have made fluorouracil-polyglycolic acid composite disks(Fu-PGA disks) with fluorouracil and biodegradable polymer: polyglycolic acid for more effective intraperitoneal chemotherapy. We inserted the Fu-PGA disk(s) in the peritoneal cavity of rat and pharmacokinetic study was performed to measure fluorouracil concentration in the peritoneal fluid, plasma, liver, kidney and heart tissue at 24 hour, 72 hour and 168 hour after insertion of Fu-PGA disk(s). Myelosuppressive action of this composite also was determined following its administration. The data of this study suggested that Fu-PGA composite will be a new device releasing drugs in a controlled manner and having targetability to peritoneum, and this device will be improving the efficacy of intraperitoneal chemotherapy for gastric adenocarcinoma.

Rat의 복강에 삽입한 Filorouracil-Polyglycolic acid제형의 Fluorouracil용출에 관한 연구

노승무,정경수,오정연,김진향,양준묵,강대영,송규상,최정목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

A common form of relapse in adenocarcinoma of the stomach is intraperitioneal dissemination, in fact, among gastric adenocarcinoma patients who have undergone surgery intended to cure, approximately 50% of the patients develope initial recurrence in the peritoneal cavity regardless of the anatomic site of the primary tumor within the stomach. The efficacy of systemic postoperative chemotherapy to prevent peritoneal recurrence of gastrric adenocarcinoma is not satisfactory. There is still a great need for improved therapeutic strategies on the disseminated microscopic disease and small miliary nodules remaining on the peritoneal surface or lymphatics after operation. The authers have made fluorouracil-polyglycolic acid composite disks(Fu-PGA disks) with fluorouracil and biodegradable polymer: polyglycolic acid for more effective intraperitoneal chemotherapy. We inserted the Fu-PGA disk(s) in the peritoneal cavity of rat and pharmacokinetic study was performed to measure fluorouracil concentration in the peritoneal fluid, plasma, liver, kidney and heart tissue at 24 hour, 72 hour and 168 hour after insertion of Fu-PGA disk(s). Myelosuppressive action of this composite also was determined following its administration. The data of this study suggested that Fu-PGA composite will be a new device releasing drugs in a controlled manner and having targetability to peritoneum, and this device will be improving the efficacy of intraperitoneal chemotherapy for gastric adenocarcinoma.

전립선비대증에 대한 α₁-아드레날린 수용체 차단제와 5α-환원효소 억제제 병합요법의 효과

노준화,오봉렬,박양일 大韓泌尿器科學會 1998 Korean Journal of Urology Vol.39 No.12

위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구

노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.

반도체소자의 고속마킹검사를 위한 vision system 개발

노영동,주효남,김주식 湖西大學校 工業技術硏究所 2005 工業技術硏究所論文集 Vol.24 No.-

In this paper, we propose the high speed making/surface inspection algorithm, that use adaptive automatic acquisition algorithm and real time matching algorithm of model data. The proposed automatic acquisition algorithm to obtain the adaptive model data extracts the interesting regions to fit in semiconductor characteristics, and create models of several semiconductor regardless of position and type. The proposed teal time matching algorithm uses geometrical pattern matching method to minimize effect of external environment of making/surface and only use semiconductor characteristic information. The proposed system has faster processing time than the conventional method. Also the proposed one has a good performance.

마늘수확 전처리 생력기계의 개발 : A Stem-Cutter and Vinyl-Remover 줄기절단 및 비닐피복 제거기

박준걸,용상호,노광모 건국대학교 자연과학연구소 1999 建國自然科學硏究誌 Vol.10 No.1

Garlic, which is one of very popular condiments in Korea, has been raised by human power because a method of mechanized cultivation is not set up completely and machinery for garlic production is not developed yet. The objectives of this paper are to develop a machine which can be used to cut garlic stems and to remove vinyls covered on soil before harvesting. To fulfil this objectives, a prototype machine consisting of a stem-cutter and a vinyl-remover was designed. Two disk blades were used as the stem-cutter, and the vinyl-remover was composed with a vinyl-cutter and a vinyl-divider. In the 1st experiment the function of the vinyl-cutter and vinyl-divider was investigated to improve their performance, and their proper locations were determined in the 2nd experiment. Also, it is observed whether garlic stems cut by two disk b lades are properly transferred backward between them. The performance of disk blades was tested in the garlic field, by changing disk speed and height of stem cutting, and overall performance of the vinyl-divider was investigated. The results showed that the angle between the center axis of vinyl-cutter and the leading edge of two vinyl-divider should be over 29 degrees, and the leading edge of dividers should be located at the same level of soil surface, for smooth operation. Also, the proper height of vinyl-cutter is 3 cm below the leading edge of divider.

트랙터 부착형 인발식 마늘수확기 개발

박준걸,노광모,용상호,장영창 建國大學校 自然科學硏究所 2002 建國自然科學硏究誌 Vol.13 No.1

A garlic harvester attached on tractor with pulling mechanism was developed in the study, based upon a kinematical analysis and related preliminary field tests on the conventional garlic harvesting method. The harvesting efficiency of the developed harvester was more than 80% in the garlic field irrigated before harvesting. The harvesting performance of the harvester was estimated to be about 400 Pyungs/hr in the irrigated field before garlic harvesting. for proper garlic drying and collection, the harvester discharged the harvested garlic on the ground uniformly at the angles of 135˚-150˚ to its forward direction with the garlic blb's placing toward the harvester. In the field test, the forward speed of the harvester ranged approximately from 0.2 m/s through 0.8 m/s. However, it was strongly recommended that the spacing of planting garlic seeds should be standardized in the near future for increasing its harvesting efficiency.

여성 복압성요실금에서 술 전 발살바요누출압에 따른 Suprapubic Arch 술식의 결과

박준명,유지형,성락희,정재용,노충희 인제대학교 2008 仁濟醫學 Vol.29 No.-

Objective : There were variant results for correlation between the postoperative cure rate and valsalva leak point pressure (VLPP) for female stress urinary incontinence (SUI). Therefore the aim of this study was to assess the influence of VLPP on the outcome of suprapubic arch (SPARC) procedure. Materials and Methods : A retrospective analysis was made of 246 women who underwent SPARC procedure for SUI. Based on VLPP, the patients were divided into 2 groups: group A (VLPP<60cmH2O) and group B (VLPP≥60cmH2O). The objective success rate and subjective success rate were assessed. Before surgery, the patients were evaluated with history taking, physical examination, urinalysis and urodynamic studies. The objective success rate was evaluated by clinical examination and the 1-hour pad test postoperatively and the subjective satisfaction rate was assessed using questionnaires for the patients' satisfaction and evaluated by recommendation rates of SPARC procedure to other patients. The objective success rate included cure and improvement, the subjective success rate included satisfaction and fair. Results : The number of patients in each group was 145 patients (group A) and 101 patients (group B). The objective success rate was 99.3% (group A) vs 98.0% (group B) (p=0.285). The subjective success rate was 98.6% (groupA) vs 98.0% (group B) (p=0.500). Recommendation rates of SPARC procedure was 94.5% (group A) vs 95.0% (group B) (p=0.422). Conclusion : It is our belief that SPARC procedure for female SUI is efficacious and safe regardless of preoperative VLPP.

장기간 혈액투석을 받는 말기 신부전환자의 정서상태 및 투석 순응도에 대한 연구

이준노,김창현,권택술 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.4

The purpose of this study is to evaluate the relationship between compliance of patients under hemodialysis and their affective states of depressed mood and anxiety. Subjects consist of 58 end-stage renal failure patients on the long-term hemodialysis of one year or longer. Depressed state was evaluated with Beck Depression Inventery(BDI) and anxiety state was assessed with Self-rating Antiety Scale(SAS). The compliance in terms of diet, medication and fluid was assessed with Potassium(K), Phosphorus(P) and Interdialytic Weight Gain(IWG), respectively. the primary findings are as noted below. 1) 58.6% of the subjects felt depressed, but anxiety level was quite within normal range. 2) There were no intercorrelations between the compliance parameters of diet, education and fluid intake. preliminary correlations are as follows. The level of depression correlated with that of anxiety. Educational level is correlated negatively with scores of depression and anxiety. Duration of marriage is correlated positively with scores of depression. 3) Only anxiety, not depression, correlated with IWG, when controlled for age, sex and other clinical variables. But, anxiety did not correlate with K and P. This result may suggest that IWG is a more sensitive indicator of compliance than K and P.