Using Comparative Genomic Hybridization Arrays (aCGH) Techniques to Detect Chronic Obstructive Pulmonary Disease Related Susceptibility Regions

Lin Hua,Zheng Yang,Ping Zhou,Li An 보안공학연구지원센터 2013 International Journal of Bio-Science and Bio-Techn Vol.5 No.2

Analysis of Plastic Penetration in Process of Groove Ball-Section Ring Rolling

Lin Hua,DongSheng Qian,LiBo Pan 대한기계학회 2008 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.22 No.7

Plastic penetration is a necessary condition of ring rolling forming. In this paper, based on the principle of groove ball-section ring rolling and characteristics of plastic penetration, a three dimensional (3D) finite element (FE) analysis model for the plastic penetration of ball groove-section ring is established under the ABAQUS software environment. A decisive factor for plastic penetration behavior, namely the penetration speed of plastic zone,has firstly been ascertained. The distribution pattern of the plastic zone in the process of plastic penetration is revealed by 3D simulation. By researching the diffusion rules of the plastic zone under the conditions of different ring radial thickness and feed speed, the influences of ring radial thickness and feed speed on plastic penetration are obtained. Lastly, the necessary condition for the plastic penetration of groove ball-section ring rolling is summarized, and is validated by experiment and simulation. The achievements of this study expressly reveal the plastic penetration rules of groove ball-section ring rolling, and it’s useful for technology design and production.

A Method Using Auxiliary Direction to Improve SURF Recall

Linhua Zhang,Xiaodong Yue 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.11

Classic SURF algorithm may lead to matching failure, low recall because of incorrect main direction when constructing feature points describing operator. To solve it, A Method using auxiliary direction to improve SURF recall is put forward. The improved algorithm first select out auxiliary direction which is similar to main direction in characteristics, then generate new operator for describing the auxiliary direction characteristic. When matching, the improved algorithm adopts stricter nearest neighbor proportion inhibition. Experimental results show that feature point recall increase about 6% compared with the classical SURF while maintaining the precision.

Stimulated Osteogenic Differentiation of Human Mesenchymal Stem Cells by Reduced Graphene Oxide

Jin, Linhua,Lee, Jong Ho,Jin, Oh Seong,Shin, Yong Cheol,Kim, Min Jeong,Hong, Suck Won,Lee, Mi Hee,Park, Jong-Chul,Han, Dong-Wook American Scientific Publishers 2015 Journal of nanoscience and nanotechnology Vol.15 No.10

Modeling of damage in cement paste subject to external sulfate attack

Chuansheng Xiong,Linhua Jiang,Yan Zhang,Hongqiang Chu 사단법인 한국계산역학회 2015 Computers and Concrete, An International Journal Vol.16 No.6

This study aimed to develop models of sulfate diffusion and ettringite content profile in cement paste for the predication of the damage behavior in cement paste subject to external sulfate. In the models, multiphase reaction equilibrium between ions in pore solution and solid calcium aluminates phases and the microstructure changes in different positions of cement paste were taken into account. The distributions of expansive volume strain and expansion stress in cement paste were calculated based on the ettringite content profile model. In addition, more sulfate diffusion tests and SEM analyses were determined to verify the reliability and veracity of the models. As the results shown, there was a good correlation between the numerical simulation results and experimental evidences. The results indicated that the water to cement ratio (w/c) had a significant influence on the diffusion of sulfate ions, ettringite concentration profile and expansion properties in cement paste specimens. The cracking points caused by ettringite growth in cement paste specimens were predicted through numerical methods. According to the simulation results, the fracture of cement paste would be accelerated when the specimens were prepared with higher w/c or when they were exposed to sulfate solution with higher concentration.

Cell-adhesive RGD peptide-displaying M13 bacteriophage/PLGA nanofiber matrices for growth of fibroblasts

신용철,이종호,Linhua Jin,김민정,오진우,김태완,한동욱 한국생체재료학회 2014 생체재료학회지 Vol.18 No.4

Background: M13 bacteriophages can be readily fabricated as nanofibers due to non-toxic bacterial virus with a nanofiber-like shape. In the present study, we prepared hybrid nanofiber matrices composed of poly(lactic-coglycolic acid, PLGA) and M13 bacteriophages which were genetically modified to display the RGD peptide on their surface (RGD-M13 phage). Results: The surface morphology and chemical composition of hybrid nanofiber matrices were characterized by scanning electron microscopy (SEM) and Raman spectroscopy, respectively. Immunofluorescence staining was conducted to investigate the existence of M13 bacteriophages in RGD-M13 phage/PLGA hybrid nanofibers. In addition, the attachment and proliferation of three different types of fibroblasts on RGD-M13 phage/PLGA nanofiber matrices were evaluated to explore how fibroblasts interact with these matrices. SEM images showed that RGD-M13 phage/PLGA hybrid matrices had the non-woven porous structure, quite similar to that of natural extracellular matrices, having an average fiber diameter of about 190 nm. Immunofluorescence images and Raman spectra revealed that RGD-M13 phages were homogeneously distributed in entire matrices. Moreover, the attachment and proliferation of fibroblasts cultured on RGD-M13 phage/PLGA matrices were significantly enhanced due to enriched RGD moieties on hybrid matrices. Conclusions: These results suggest that RGD-M13 phage/PLGA matrices can be efficiently used as biomimetic scaffolds for tissue engineering applications.

Chloride diffusion in concrete associated with single, dual and multi cation types

Zijian Song,Linhua Jiang,Ziming Zhang 사단법인 한국계산역학회 2016 Computers and Concrete, An International Journal Vol.17 No.1

Currently, most of the investigations on chloride diffusion were based on the experiments and simulations concerning single cation type chlorides. Chloride diffusion associated with dual or multi cation types was rarely studied. In this paper, several groups of diffusion experiments are conducted using chloride solutions containing single, dual and multi cation types. A multi-ionic model is also proposed to simulate the chloride diffusion behavior in the experimental tests. The MATLAB software is used to numerically solve the nonlinear PDEs in the multi-ionic model. The experimental and simulated results show that the chloride diffusion behavior associated with different cation types is significantly different. When the single cation type chlorides are adopted, it is found that the bound rates of chloride ions combined with divalent cations are greater than those combined with monovalent cations. When the dual/multi cation type chlorides are adopted, the chloride bound rates increase with the Ca2+/Mg2+ percentage in the source solutions. This evidence indicates that the divalent cations would markedly enhance the chloride binding capacity and reduce the chloride diffusivity. Moreover, on the basis of the analysis, it is also found that the complicated cation types in source solutions are beneficial to reducing the chloride diffusivity.

Experimental research and molecular dynamics simulation on thermal properties of capric acid/ethylene-vinyl/graphene composite phase change materials

Yue Gu,Linhua Jiang,Weizhun Jin,Zhenhua Wei,Xing Liu,Mingzhi Guo,Kailun Xia,Lei Chen 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.99 No.-

In this paper, a new series of phase change materials (PCMs) composed of capric acid/ethylene-vinylacetate/graphene (CA/EVA/GR) were prepared and thermal properties were investigated using moleculardynamics simulation. The composite PCMs were characterized by Fourier transform infraredspectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), differential scanningcalorimetry (DSC) and thermal conductivity measurement. FT-IR, XRD and SEM results manifest that CAcan be successfully wrapped by EVA and GR additives, and there is no chemical reaction between CA, EVAand GR. DSC results indicate that adding GR into CA/EVA can result in composite PCMs maintain the highlatent heat, while too much GR will cause a significant reduction in latent heat. Thermal conductivityobtained from experimental tests reveal that GR can gradually enhance the thermal conductivity of CA/EVA with increasing dosage of GR. The experimental results of thermal conductivity fall close to that ofmolecular dynamics (MD) simulation at GR dosages below 1.8 wt%, but the experimental results present atrend which is contrary to MD simulation at higher GR dosages. The mean square displacement (MSD)results manifest that composite PCMs containing 1.8 wt% GR has the highest diffusion coefficient, whilehigher GR dosage will reduce the diffusion coefficient gradually.

Performance analysis and saturation bound research of cyclic-quorum multichannel MAC protocol based on Markov chain model

( Xing Hu ),( Linhua Ma ),( Shaocheng Huang ),( Jinke Huang ),( Kangning Sun ),( Tianyu Huang ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.8

In high diversity node situation, single-channel MAC protocols suffer from many collisions. To solve this problem, the research of multichannel MAC protocol has become a hotspot. And the cyclic quorum-based multichannel (CQM) MAC protocol outperformed others owing to its high frequency utilization. In addition, it can avoid the bottleneck that others suffered from and can be easily realized with only one transceiver. To obtain the accurate performance of CQM MAC protocol, a Markov chain model, which combines the channel hopping strategy of CQM protocol and IEEE 802.11 distributed coordination function (DCF), is proposed. The metrics (throughput and average packet transmission delay) are calculated in performance analysis, with respect to node number, packet rate, channel slot length and channel number. The results of numerical analysis show that the optimal performance of CQM protocol can be obtained in saturation bound situation. And then we obtain the saturation bound of CQM system by bird swarm algorithm (BSA). Finally, the Markov chain model and saturation bound are verified by Qualnet platform. And the simulation results show that the analytic and simulation results match very well.

Evaluation and Prediction on the Hydraulic Abrasion Performance of High Belite Cement-Based Concrete

Chunmeng Jiang,Linhua Jiang,Cheng Chen,Jingwei Gong,Shuangxi Li 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.6

High belite cement (HBC) concrete is increasingly applied to the hydraulic projects, where much attention should be paid to the abrasion performance. In this paper, the mass loss, abrasion rate and morphology indexes such as depth of abrasion, volume loss and fractal dimension of HBC-based concrete at different wear periods were determined through underwater method. Moreover, a new method by transforming the survey area of worn surface was put forward to simulating practical erosion conditions, based on which, the abrasion performance prediction model was built by Projection Pursuit Regression (PPR) theory. Results show that the compounding addition of 30% mineral admixtures had little contribution to the abrasion resistance of HBC concrete after being long-term cured, while reducing water-binder (w/b) ratios was still an effective way for improving that. The worn surface of concrete specimens was divided into three regions for abrade zone, transitional zone and sound zone, and the abrasion evolution was found to be related to the wear duration and space position. Furthermore, there were good correlations between mass loss rate, depth of abrasion, volume loss and fractal dimension, and the fitting formulas were also proposed with good coefficients. Eventually, the PPR model based on the data of transformed survey area was proved to be a promising approach for predicting the abrasion performance.