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- 저자 : Kavitha (검색결과 126 건)
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Kavitha 보안공학연구지원센터 2016 International Journal of Software Engineering and Vol.10 No.6
At the present time, computerized tests are one of the most critical means to evaluate learning. Choosing tailored questions for each learner is a important part of such tests. Since, wide and varied learners with different abilities are involved, even randomized test cannot serve the purpose of assessment. Some form of personalized and intelligent testing is needed in E-Learning. One of the main components in composing intelligent testing is selecting the items from a huge Item Bank as the accuracy of the test depends on the quality of the assessment which in turn depends on the items selected for assessment. Furthermore, pickingappropriate items is critical in developing as assessment sheet that satisfies multiple criteria. It includes the number of test items, the definitedissemination of course concepts to be assessed, and the expected degree of difficultness and discrimination and exposure frequency. These tests, must effectively select questions from a large item bank, and to manage this problem an optimized assessment sheet composition system using the modified form of nature inspired Intelligent Water Drops optimization algorithm is proposed by embedding a local heuristic as evolutionary operator. This system is designed to choosepersonalizedtest items for each and every learner. Furthermore, the proposed approach is able to effectively generate near optimal items from large item bank that satisfy multiple constraints. The results show that the Evolutionary Intelligent Water Drops approach is suitable for the selection of nearoptimal items from large-scale item bank.
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Kavitha, M.,Kalaimagal, I.,Mercy, S.,Sangeetha, N.,Ganesh, D. Institute of Forest Science 2009 Journal of Forest Science Vol.25 No.2
Multiple shoot induction and plant regeneration using apical bud and nodal explants of 100 year old tree of Anthocephalus cadamba, an important sacred and medicinal tree in India was achieved for the first time. Aseptic explants cultured in Murashige and Skoog (MS) medium augmented with different concentrations of BAP (0.1, 0.5, 1.0, 2.5, 5.0 and 10 mg/l), when maintained for 60 days, healthy shoots were induced in presence of BAP (1 mg/l). Lower concentrations of BAP (0.1 - 0.5 mg/l) induced only one shoot per explant. Increase in number of shoots per explant was observed in presence of higher concentrations of BAP (2.5, 5.0 and 10 mg/l). However, elongation of shoots was completely inhibited. Bud break and shoot regeneration was largely associated with seasonal factors. Apical buds cultured during June to August exhibited early bud break within two weeks of initial culture. In rest of the months, bud break and shoot regeneration was very slow irrespective of the various concentrations of BAP used in the medium. Explants sourced from three different maturity levels of shoots indicated that actively growing shoots from the mother plant with 1 - 2 nodal segments was more suitable for culture initiation than the explants collected from mature shoots at dormant stage. Regenerated shoots with 2 - 3 pairs of leaves when transferred to half strength MS medium fortified with IBA (1 mg/l), 60% of the shoots induced healthy roots, indicating the possibility of large scale micropropagation.
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Kavitha, Anbukumar,Uma, Govindarajan The Korean Institute of Electrical Engineers 2010 Journal of Electrical Engineering & Technology Vol.5 No.1
Resonant parametric perturbation (RPP) method is an effective non-feedback method for controlling chaos. In this paper, the above method is applied for the current programmed buck-boost dc-dc converter which exhibits chaotic for wide parameter variations. The different possible operating regimes leading to chaotic operation of the current mode controlled buck-boost converter is discussed and the control of chaos by RPP method is demonstrated through computer simulations and experimental studies. The converter is stabilized to period 1 operation practically.
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Glucose sensing, photocatalytic and antibacterial properties of graphene-ZnO nanoparticle hybrids
Kavitha, T.,Gopalan, A.I.,Lee, K.P.,Park, S.Y. Pergamon Press ; Elsevier Science Ltd 2012 Carbon Vol.50 No.8
A simple and efficient approach was developed to uniformly decorate graphene nanosheets with zinc oxide (ZnO) nanoparticles. A single source precursor, zinc benzoate dihydrazinate complex, has been used for the in situ generation of ZnO nanoparticles onto graphene at a relatively low temperature, 200<SUP>o</SUP>C. Physico chemical analyses such as X-ray diffraction, transmission electron microscopy and X-ray photoelectron spectroscopy revealed that ZnO nanoparticles were finely dispersed on the surface of graphene. ZnO-graphene hybrids were further characterized by Raman spectroscopy and ultraviolet visible spectroscopy and room-temperature photoluminescence. The materials exhibited excellent photocatalytic activity as evident from the degradation of methylene blue in ethanol under UV irradiation. An electrochemical glucose biosensor was fabricated by immobilization of glucose oxidase on the ZnO-graphene hybrids. This biosensor showed improved sensitivity towards glucose as compared to graphene. Also, the hybrids showed significant antibacterial activity against E. coli, gram negative bacteria. This simple and economical preparation strategy may be extended for the preparation of other graphene-based hybrids.
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Kavitha, Thangavelu,Haider Abdi, Syed Izhar,Park, Soo-Young The Royal Society of Chemistry 2013 Physical chemistry chemical physics Vol.15 No.14
<P>Graphene oxide (GO) was functionalized covalently with pH-sensitive poly(2-(diethylamino) ethyl methacrylate) (PDEA) by surface-initiated <I>in situ</I> atom transfer radical polymerization. The structure of the PDEA-grafted GO (GO-PDEA) were examined by Fourier-transform infrared spectroscopy, proton nuclear magnetic resonance spectroscopy, X-ray photoelectron spectroscopy, thermogravimetric analysis and atomic force microscopy. The grafted PDEA endowed the GO sheets with good solubility and stability in physiological solutions. Simple physisorption by π–π stacking and hydrophobic interactions on GO-PDEA can be used to load camptothecin (CPT), a widely used water-insoluble cancer drug. The loaded CPT was released only at the lower (acidic) pH normally found in a tumor environment but not in basic and neutral pH. GO-PDEA did not show practical toxicity to N2a cancer cells but the GO-PDEA-CPT complex exhibited high potency in killing N2a cancer cells <I>in vitro</I>. These results suggest that the GO-PDEA nanocargo carrier might be a promising material for site-specific anticancer drug delivery and controlled release.</P> <P>Graphic Abstract</P><P>PDEA-grafted graphene oxide is a promising material for site-specific anticancer drug delivery and controlled release. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3cp00008g'> </P>
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Kavitha Srinivasa,최원자,Jihyun Kim,Subog Yee,김완기 한국분자세포생물학회 2012 Molecules and cells Vol.33 No.2
Hydrogen peroxide (H2O2) functions as a ubiquitous intracellular messenger besides as an oxidative stress molecule. This dual role is based on the distinct cellular responses against different concentrations of H2O2. Previously, we demonstrated that both low (> 1 mM) and high (4-10 mM) doses of exogenous H2O2 induce filamentous growth with distinct cell morphology and growth rate in Candida albicans, suggesting the different transcription response. In this study, we revealed that the sub-toxic and toxic levels of H2O2 indeed induced pseudohyphae, but not true hyphae. Supporting this, several hyphae-specific genes that are expressed in true hyphae induced by serum were not detected in either sub-toxic or toxic H2O2 condition. A DNA microarray analysis was conducted to reveal the transcription profiles in cells treated with sub-toxic and toxic conditions of H2O2. Under the sub-toxic condition, a small number of genes involved in cell proliferation and metabolism were up-regulated, whereas a large number of genes were up-regulated in the toxic condition where the genes required for growth and proliferation were selectively restricted. For pseudohyphal induction by sub-toxic H2O2, Cek1 MAPK activating the transcription factor Cph1 was shown to be important. The absence of expression of several hyphae-specific genes known to be downstream targets of Cph1-signaling pathway for true hyphae formation suggests that the Cek1-mediated signaling pathway is not solely responsible for pseudohyphal formation by sub-toxic H2O2 and, but instead, complex networking pathway may exists by the activation of different regulators.
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Kavitha, Nowroji,Vijayarathna, Soundararajan,Jothy, Subramanion Lachumy,Oon, Chern Ein,Chen, Yeng,Kanwar, Jagat Rakesh,Sasidharan, Sreenivasan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.18
MicroRNAs (miRNAs) are short non-coding RNAs of 20-24 nucleotides that play important roles in carcinogenesis. Accordingly, miRNAs control numerous cancer-relevant biological events such as cell proliferation, cell cycle control, metabolism and apoptosis. In this review, we summarize the current knowledge and concepts concerning the biogenesis of miRNAs, miRNA roles in cancer and their potential as biomarkers for cancer diagnosis and prognosis including the regulation of key cancer-related pathways, such as cell cycle control and miRNA dysregulation. Moreover, microRNA molecules are already receiving the attention of world researchers as therapeutic targets and agents. Therefore, in-depth knowledge of microRNAs has the potential not only to identify their roles in cancer, but also to exploit them as potential biomarkers for cancer diagnosis and identify therapeutic targets for new drug discovery.
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Kavitha, S.,Rajesh Banu, J.,Subitha, G.,Ushani, U.,Yeom, I.T. Elsevier Applied Science 2016 Bioresource technology Vol.219 No.-
The objective of this study was to determine the impact of solubilization during thermo-chemo-sonic pretreatment of waste activated sludge (WAS) on anaerobic biodegradability and cost for biogas production. The results revealed that it was possible to achieve 40-50% of solubilization of WAS when ultrasonic energy input was doubled (11,520-27,000kJ/kgTS). The cost to achieve 30-35% of solubilization of WAS was calculated to be 0.22-0.24USD/L, which was relatively lower than the cost of 0.53-0.8USD/L when 40-50% of solubilisation of WAS was achieved. There was no significant difference in biodegradability (0.60-0.64gCOD/gCOD) for samples with solubilization efficiency of 35-50%. Comparing energetic balance and economic assessment of samples with different solubilization percentages, the results showed that samples with 30-35% of solubilization had lower net cost (7.98-2.33USD/Ton of sludge) and negative energy balance compared to samples with other percentages of solubilization.
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