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      • 저압 MOCVD법에 의한 (100)-GaAs 기판 위의 Ga_xIn(1-x)P 성장과 특성

        전성란,손성진,조금재,박순규,김영기 全北大學校 基礎科學硏究所 1994 基礎科學 Vol.17 No.-

        x??0.51인 Ga_xIn_(1-x)P 에피층을 저압 MOCVD 성장법으로 TEGa(triethylgallium), TMIn(trimethylindium) 등의 MO(metalorganic) 원료와 PH_3(phosphine)를 사용하여 GaAs(100) 기판 위에 성장하였다. 성장조건에 의한 표면 morphology, 결정결함, 성분비, PL spectra, 운반자 농도와 이동도 및 DLTS spectra와 같은 성장층의 특성을 관찰하였다. 650℃의 성장온도와 V/Ⅲ 비, 즉 TEGa와 TMIn 두 원료의 유량에 대한 PH_3의 유량비가 160∼220일 때 가장 좋은 성장표면을 나타내었다. 성장률은 PH_3의 유량변화에 아무런 영향을 받지 않음을 알 수 있었다. Ga_0.51In_0.49P 에피층과 기판의 격자상수 차에 의한 격자 부정합 Δa_⊥/a_0은 약 (3.7∼8.9)×10 exp (-4)이었으며 실온과 5K에서 에피층의 PL 피크 에너지는 각각 1.85 eV와 1.9 eV였다. 성장층의 운반자 농도와 이동도는 V/Ⅲ 비에 따라 달라지는데 그 비가 120에서 220으로 증가함에 따라 농도는 1.8×10 exp (16) ㎝^-3에서 8.2×10 exp (16) ㎝^-3로 증가하였고 이동도는 1010 ㎝/V·sec에서 366 ㎝/V·sec로 감소하였다. Epitaxial layers of Ga_xIn_(1-x)P with x??0.51 were grown on the GaAs substrates oriented 2℃ off (100) toward <110> by low pressure MOCVD growth technique using triethylgallium (TEGa), trimethylindium (TMIn) and phosphine (PH_3). Surface morphology, crystal defects, composition, photoluminescence spectra, carrier concentration and DLTS spectra of the grown layers were investigated. Good quality epilayers with featureless surface were obtained at growth temperature of 650℃ and V/Ⅲ ratio, i.e., PH_3 flow rate divided by the sum of TEGa and TMIn flow rates, of 160 to 220. The growth rate turned out to have no dependence on phosphine flow rate. The lattice mismatchs Δa_⊥/a_0 between grown Ga_0.51In_0.49P epilayer and GaAs substrate were (3.7∼8.9)×10 exp (-4) and the PL peak energies of the epitaxial layer at room temperature and 5K were 1.85 eV and 1.9 eV, respectively. With increasing V/Ⅲ ratio i.e., phosphine flow rate, from 120 to 220, the carrier density and mobility of undoped epitaxial layers increased from 1.8×10 exp (16) to 8.2×10 exp (16) ㎝^-3 and decreased from 1010 to 366 ㎝/V·sec, respectively.

      • 14個 對稱中心點群의 等價回折面關係式

        李珍昊,秋錦洪,徐日煥,林星秀,柳保盈,朴晶蘭 충남대학교 자연과학연구소 1993 忠南科學硏究誌 Vol.20 No.1

        The planes belonging to the 230 space groups have been classified into 14 equivalent plane relations according to the symmetry of Laue groups.

      • 粉末法을 爲한 多重度 因子

        徐日煥,秋錦洪,李珍昊,林星秀,柳保盈,朴晶蘭,金憲俊,成百石,李正秀,金文執 충남대학교 자연과학연구소 1993 忠南科學硏究誌 Vol.20 No.1

        The multiplicity factor, which may be defined as the number of different planes in a form having identical interplanar spacing and identical intensity, is tabulated here for eleven Laue groups on the basis of their symmetries.

      • 21個 非對稱中心點群의 等價逆格子點

        徐日煥,秋錦洪,李珍昊,朴晶蘭,郭相姬,金文執,李正秀,申容賢 충남대학교 자연과학연구소 1994 忠南科學硏究誌 Vol.21 No.2

        32개 點群은 中心對稱(centrosymmetric)을 갖는 11가지 點群(Laue群)과 21個의 非對稱中心(noncentrosymmetric)點群으로 이루어졌다. 本 硏究에서는 21個 非對稱中心點群 各各의 等價回折面(等價逆格子點)들을 誘導하였다. The thirty two point groups consist of eleven Laue groups (centrosymmetric point groups) and twenty one noncentrosymmteric point groups. In this paper, the reciprocal lattice points equivalent under the operations of 21 noncentrosymmetric point groups are derived.

      • 진세노사이드 Rd와 사포닌 대사물인 compound K의 항지질과산화 효과

        김경현,성금수,문연자,박시준,신미란,장재철 한국전통의학연구소 2006 한국전통의학지 Vol.15 No.1

        To study on antioxidant effects in the liver of 40-week-old mouse, the sample were orally pretreated 5mg/kg/day for 5 days with red ginseng saponin components(total saponin, protopanaxadiol saponin, protopanaxatriol saponin, ginsenoside-Rd, ginsenoside-Re, compound-K) for 5 days. The ability of saponin to protect the mouse liver from oxidative damage was examined by determining the activity of superoxide dismutase(SOD), glutathione peroxidase(GPx) and the contents of glutathione, the level of malondialdehyde. The only protopanaxadiol among the ginseng saponin fractions was significantly increased the hepatic SOD activity(p<0.01). The red ginseng saponin induced a slight increase of GPx activity, especially ginsenoside Rd, compound K and protopanaxatriol treatments significantly increased its activity. The content of glutathione was significantly increased by total saponin, protopanaxadiol and ginsenoside Rd(p<0.01), but the oxidized glutathione level was lowered in all the red ginseng saponin. Finally, the level of malondialdehyde was significantly decreased by ginsenoside Rd and protopanaxadiol. In conclusion, protopanaxadiol and ginsenoside Rd among the saponin fraction were especially increased in the activity of hepatic antioxidative enzyme and decreased the lipid peroxidation that was expressed in term of MDA formation. This comprehensive antioxidant effects of red ginseng saponin seems to be by a certain action of saponin other than a direct antioxidant action.

      • Reciprocal Lattice Explorer의 原理와 使用法

        徐日煥,李珍昊,秋錦洪,林星秀,柳保盈,朴晶蘭,金文執,趙素羅,金憲俊,李正秀,成百石 충남대학교 자연과학연구소 1993 忠南科學硏究誌 Vol.20 No.2

        Reciprocal lattice explorer는 de Jong-Bouman camera와 Buerger precession camera를 合친것이다. 이 explorer를 使用하면 goniometer에 한번 固定한 試料를 使用하여 그 試料의 空間群을 決定하는데 必要한 모든 寫眞을 撮影할 수 있으며 그들은 찌그러지지 않은 逆格子面의 寫眞들이다. 本 論文에서는 de Jong-Bouman 과 Buerger precession 寫眞術의 原理와 使用法을 記述 하였고 또한 de Jong-Bouman의 振動寫眞과 zeroth layer 寫眞으로부터 11個 Laue群의 識別方法도 提示하였다. The reciprocal lattice explorer is an instrument which incorporates the principles of both the Buerger precession and the de Jong-Bouman methods. On the explorer all photographs which are necessary for a space group determination can be taken with a single setting of a crystal and the photographs show undistorted pictures of the reciprocal lattice planes. In this paper, the principles and the usages of the de Jong-Bouman and the Buerger precession photography are described, and a method of 11 Laue group identification using the de Jong-Bouman oscillation and zeroth layer photographs is shown.

      • 라벤더 에탄올 추출물의 피지생성 억제효과

        박시준,김호민,한규수,성금수,신미란,문연자,우원홍 한국전통의학연구소 2006 한국전통의학지 Vol.15 No.1

        Lavandula vera is indispensable member of the herb family, used for perfumes and potpourri. Androgens have profound effects on the physiology of the sebaceous gland. Sebum is secreted due to the effect of androgen, which starts to be secreted at puberty. Using the human sebocyte cell line SZ95, the author investigated the inhibitory effect of Lavandula vera on the lipid production. Light microscopic finding were examined numerous cytoplasmic lipid droplets SZ95 cells by Oil red staining and lipid droplets were increased markedly by testosterone. On the other hand, combined treatment with Lavandula vera and testosterone resulted in a lower lipid droplets than with testosterone alone in a dose-dependent manner. These findings indicate that Lavandula vera acts antagonistically to testosterone and inhibits the lipid synthesis of SZ95 cells at the cellular level.

      • KCI등재

        Current medical treatment of uterine fibroids

        ( Geum Seon Sohn ),( Sihyun Cho ),( Yong Man Kim ),( Chi-heum Cho ),( Mee-ran Kim ),( Sa Ra Lee ) 대한산부인과학회 2018 Obstetrics & Gynecology Science Vol.61 No.2

        Uterine fibroids (leiomyomas or myomas), benign monoclonal tumors, are the most common benign tumors in women. Heavy or prolonged menstrual bleeding, abnormal uterine bleeding, resultant anemia, pelvic pain, infertility, and/or recurrent pregnancy loss are generally associated with uterine fibroids. Although curative treatment of this tumor relies on surgical therapies, medical treatments are considered the first-line treatment to preserve fertility and avoid or delay surgery. The aim of this review is to provide available and emerging medical treatment options for symptomatic uterine fibroids. Literature review and consensus of expert opinion. Many uterine fibroids are asymptomatic and require no intervention, although it is advisable to follow-up patients to document stability in size and growth. Fibroid-associated symptoms include heavy menstrual bleeding and pain or pelvic discomfort. The association between infertility and fibroids increases with age. Treatment options for symptomatic uterine fibroids ― include medical, surgical, and radiologically guided interventions. Various medical therapies are now available for women with uterine fibroids, although each therapy has its own advantages and disadvantages. Currently, gonadotrophin-releasing hormone (GnRH) agonists and selective progesterone receptor modulators (SPRMs) are the most effective medical therapies, with the most evidence to support their reduction of fibroid volume and symptomatic improvement in menstrual bleeding. The choice of treatment depends on the patient's personal treatment goals, as well as efficacy and need for repeated interventions.

      • KCI등재SCOPUS

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