http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
이석우,장병만,이광일,이기창,Suck-Woo Lee,Byung-Man Jang,Gwang Il Lee,Gi Chang Lee 대한화학회 1992 대한화학회지 Vol.36 No.6
N-Benzylidenebenzenesulfonamide 유도체의 가수분해 반응속도를 $25^{\circ}C$의 수용액에서 자외선 분광기를 사용하여 측정하고 넓은 pH 범위에 적용될 수 있는 반응속도식을 유도하였다. 가수분해 반응속도에 미치는 치환기 효과를 검토하기 위하여 Hammett plot를 한 결과 전자 끄는기에 의하여 반응속도가 촉진됨을 알 수 있었다. 가수분해 최종 생성물은 benzenesulfonamide와 benzaldehyde 이었으며 가부분해 반응속도 상수 측정과 반응속도식의 유도, 치환기 효과, general base 효과 및 최종생성물의 결과로부터 n-benzylidenebenzenesulfonamide 유도체의 가수분해 반응은 pH 0.2${\sim}$2.5에서는 hydronium ion에 의해서, pH 3.0${\sim}$8.0 사이에서는 중성의 물분자에 의하여 가수분해가 일어나고 pH 8.5 이상에서는 hydroxide ion에 의하여 진행됨을 알 수 있었다. The kinetics of the hydrolysis of N-benzylidenebenzenesulfonamide derivatives have been investigated by ultraviolet spectrophotometry in $H_2O$ at $25^{\circ}C$. A rate equation which can be applied over a wide pH range was obtained. The substituent effect on the hydrolysis of N-benzylidenebenzenesulfonamide derivatives were studied and rate of hydrolysis is known to be accelerated by electron withdrowing group. Final product of the hydrolysis was benzenesulfonamide and benzaldehyde. Base on the rate equation, substituent effect, general base effect and final products, hydrolysis of N-benzylidenebenzenesulfonamide derivatives seemed to be initiated by the hydronium ion at the pH 0.2${\sim}$2.5 and proceeded by the neutral $H_2O$ molecule at pH 3.0${\sim}$8.0 but proceeded by the hydroxide ion at above pH 8.5.
α-Phenyl-N-iso-Propylnitrone 유도체의 가수분해 반응 메카니즘과 반응 속도론적 연구
곽천근,장병만,이석우,이기창 ( Chun Geun Kwak,Byung Man Jang,Seok Woo Lee,Ki Chang Lee ) 한국유화학회 1994 한국응용과학기술학회지 Vol.11 No.1
The rate constants of hydrolysis of α-phenly-N-iso-propylnitrone and its derivatives have been determined by UV spectrophotmetry at 25℃ and a rate equation which can be applied over a wide pH range was obtained. On the basis of rate equations derived and judging from the hydrolysis products obtained and general base and substituent effect, plausible mechanism of hydrolysis in various pH range have been proposed. Below pH 4.5, the hydrolysis was initiated by the protonation and followed by the addition of water to α-carbon. Above pH 10.0, the hydrolysis was proceeded by the addition of hydroxide ion to α=carbon. In the range of 4.5~10.0, the addition of water to nitrone was rate controlling step.
Dihydro-1,4-oxathiin 유도체의 가수분해 Mechanism과 반응속도론적 연구
이광일,곽천근,장병만,김영주,한호규,남기달,이기창,Lee, Kwang Il,Kwak, Chun Geun,Jang, Byung Man,Kim, Young Ju,Hahn, Hoh Gyu,Nam, Kee Dal,Lee, Ki Chang 대한화학회 1996 대한화학회지 Vol.40 No.2
Dihydro-1, 4-oxathiin 유도체의 가수분해 반응속도를 25.deg.C의 수용액에서 자외선 분광기를 사용하여 측정하고 넓은 pH범위에서 적용될 수 있는 반응속도식을 유도하였다. 가수분해 반응속에에 미치는 치환기 효과를 검토하기 위하여 Hammett plot한 결과 전자 끄는기에 의하여 반응속도가 촉진됨을 확인할 수 있었다. 가수분해 최종 생성물은 2-(2-hydroxyethylthio)acetoacetanilide enol형이었다. 가수분해 반응속도상수 측정실험과 반응식 유도과장, 일반염기 효과, 치환기 효과 및 최종 생성물의 결과로부터 dihydro-1, 4-oxathiin 유도체의 기수분해 반응 메카니즘을 제안하였다. pH3.5이하에서는 양서자가 첨가된 dihydro-1, 4-oxathiin의 2번 탄소에 물분자의 공격에 의해 진행되며, pH3.5 이상에서는 2번 탄소에 히드록시이온의 첨가에 의하여 진행됨을 알 수 있었다. pH4.0-9.0사이에서는 dihydro-1, 4-oxathiin에 중성의 물분자가 첨가되는 것이 속도결정단계임을 알았다. The kinetics of the hydrolysis of dihydro-1, 4-oxathiin derivatives were investigated by ultraviolet spectrophotometry in H2O at $25^{\circ}C.$ A rate equation which can be applied over a wide pH range was obtained. The substituent effects on the hydrolysis of dihydro-1, 4-oxathiin derivatives were studied and the rate of hydrolysis was shown to be accelerated by electron accepting groups. Final product of the hydrolysis was 2-(2-hydroxyethylthio)acetoacet-anilide enol form. On the basis of rate equations derived and judging from hydrolysis products obtained and from general base effect and substituent effects, plausible mechanism of the hydrolysis in various pH range have been proposed. Below pH 3.5, the hydrolysis was initiated by the protonation and followed by the addition of water to 2-carbon. Above pH 10.0, the hydrolysis was proceeded by the addition of hydroxide to 2-carbon. In the range of pH 4.0∼10.0, the addition of water to dihydro-1,4-oxathiin is rate controlling step.
임우택 ( Woo Taik Lim ),장병대 ( Byung Dae Jang ),박만 ( Man Park ),정성욱 ( Sung Wook Jung ),장창환 ( Chang Hwan Chang ),허남호 ( Nam Ho Heo ) 한국공업화학회 2002 공업화학 Vol.13 No.7
겔 조성과 합성조건의 조정으로 순수한 제올라이트 Rho 결정들이(gel 조성, 3.11Na : o.31Cs : 1.0AJ : 5.69Si : 55.5H_2O) 유기성 구조유도체 없이 실온에서 5일 동안의 숙성에 의해서 합성되어졌다. 합성된 제올라이트 Rho 결정들의 평균 크기는 약 2㎛로 추정되어졌으며 Si/Al 비는 3.54이었고 물함량은 15.9%이었다(Na_4.96Cs_5.60Si_37.44Al_10.56O_96ㆍ39H_2O). 제올라이트 Rho의 골격은 Si(0AJ), Si(1Al) 및 Si(2Al)로 구성되어져 있는 것으로 나타났으며 약 1000 ℃까지 안정하였다. with the aging time of 5 days at room temperature, in the absence of organic structure-directing agents, nearly pure Rho zeolite was synthesized from a gen composition of 3.11Na : 0.31Cs : 1.0AJ : 5.69Si : 55.5H_2O. This study was conducted to improve the purity of Rho crystals through modification of the gel composition and the process condition. The average size of synthesized Rho crystals was estimated to be ca, 2 ㎛. The formula of zeolite Rho unit cell was found to be Na_4.96Cs_5.60Si_37.44Al_10.56O_96ㆍ39H_2O with Si/Al ratio = 3.54 and 15.9% of water content. The framework of Rho zeolite was composed of Si(0Al), Si(1Al) 및 Si(2Al), and it was thermally stable up to about 1000 ℃.
α-phenyl-N-iso-propylnitrone유도체에 대한 1-propanethiol의 친핵성 첨가반응에 관한 연구
이광일(Lee Kwang Il)(李光一),곽천근(Kwak Chun Geun)(郭仟根),장병만(Jang Byung Man)(張炳萬),김영주(Kim Young Ju)(金榮珠),지윤섭(Ji Yun Seup)(池允燮),이기창(Lee Ki Chang)(李基昌) 한국유화학회 1995 한국응용과학기술학회지 Vol.12 No.2
The rate constant of the nucleophilic addition of 1-propanethiol to α-phenyl-N-iso-propylnitrone derivatives were determined at various pH and a rate equation which can be applied over wide pH range is obtained. Final product of the addition reaction was α-thiopropyl-p-phenylbenzylideneamine. Base on the rate equation, general base effect, substituent effect and final product, plausible mechanism of addition reaction have been proposed. Below pH 3.0, the reaction was initiated by the addition of 1-propanthiol, and in the range of pH 3.0-10.0, proceeded by the competitive addition of 1-propanethiol and propanethiolate. Above the pH 10.0, the reaction proceeded through the addition of propanethiolate.
대도시권 대중교통 환승센터의 이동편의시설 서비스수준에 대한 연구
김성은(Kim Sung-Eun),김시곤(Kim Si-Gon),장병만(Jang Byung-Man) 한국철도학회 2007 한국철도학회 학술발표대회논문집 Vol.- No.-
This paper suggests a new Level of Service (LOS) for a pedestrian facility in a transportation transfer center. They include the road, stair, and waiting place for a pedestrian. A current situation of several pedestrian facility was surveyed for the existing transportation transfer center at both Seoul and Pusan metropolitan cities. A new LOS was developed based on the output according to foreign criteria as well as an interview of pedestrians for their satisfaction.
간장질환 치료용 의약조성물 ( DWP 305 ) 의 이반약리작용
심점순(Jeom Soon Shim),박남준(Nam Jun Park),유영효(Young Hyo Yu),임승욱(Seung Wook Lim),염제호(Je Ho Yeom),김영만(Young Man Kim),장병수(Byeong Su Jang),박명환(Myung Hwon Park),연제덕(Je Duk Yeon),김병오(Byung O Kim),강진석(Jin Seok K 한국응용약물학회 1994 Biomolecules & Therapeutics(구 응용약물학회지) Vol.2 No.2
The general and some pharmacological actions of DWP 305 were investigated in animals and the following results were obtained. In central nervous system, DWP 305 had no effects on the pentobarbital induced anaesthesia, locomotor activity, rotarod test, traction test, analgesic action in mice and body temperature in rat. DWP 305 showed no depressive action on convulsion induced by strychnine, electronic shock and pentylenetetrazole. From these results, DWP 305 was considered to have no pharmacological effect on the central nervous system. Furthermore, DWP 305 had no influences on the normal blood pressure and heart rate. In the isolated ileum of guinea pig, DWP 305 inhibited contrastive effects against the acetylcholine (10^(-6)g/㎖), histamine (10^(-6)g/㎖), 5-hydroxytryptamine (10^(-6)g/㎖) and BaCl₂ (10^(-4)g/㎖) at a concentration of 2.15 X 10^(-4)g/㎖ in bath. In the isolated trachea and vas deference, DWP 305 showed no effect on the contractions produced by histamine and norepinephrine, respectively. DWP 305 showed inhibitory effect on the contractions produced by acetylcholine and oxytocin at a concentration of 2.15 X 10^(-4)g/㎖ on the isolated nonpregnant rat uterus. DWP 305 had no effect on the isolated right atrium of guinea pig, bile excretion urine volume, pH, gastrointestinal motility, gastric secretion and blood aggregation.
위장질환 치료용 의약조성물 ( DWP 301 ) 의 일반약리작용
심점순(Jeon Soon Shim),박남준(Nam Jun Park),유영효(Young Hyo Yu),임승욱(Seung Wook Lim),염제호(Je Ho Yeom),김영만(Young Man Kim),장병수(Byeong Su Jang),연제덕(Je Duk Yeon),김병오(Byung O Kim),강진석(Jin Seok Kang),유은주(Eun Joo Yu) 한국응용약물학회 1994 Biomolecules & Therapeutics(구 응용약물학회지) Vol.2 No.4
The general and some pharmacological actions of DWP 301 were investigated in animals and the following results were obtained. In central nervous system, DWP 301 had no effects on the pentobarbital induced anaesthesia, rotarod test, traction test, analgesic action, anticonvulsant action in mice and body temperature in rat. But DWP 301 showed a little decrease of locomotor activity at a dose of 3,000 mg/kg. From these results, DWP 301 was considered to have little pharmacological effect on the central nervous system. Furthermore, DWP 301 had no influences on the normal blood pressure and heart rate. DWP 301 showed no effect on the isolated guinea pig ileum, trachea, right atrium, and nonpregnant rat uterus. But, in the isolated guinea pig vas deference, DWP 301 had showed inhibitory effect on the contractions produced by norepinephrine. DWP 301 showed rise of gastric juice pH and decrease of urine volume. Also, DWP 301 had no effect on the gastrointestinal motility and blood aggregation. From these results, it is concluded that the general pharmacological effect of DWP 301 are similar to or weaker than M and AGA.