일개 광역자치단체 주민의 심근경색증 조기증상 인지도와 관련요인

나윤주 ( Yoon Joo Na ),이유미 ( Yu Mi Lee ),김건엽 ( Keon Yeop Kim ),최연희 ( Yeon Hee Choi ) 한국보건정보통계학회 2015 보건정보통계학회지 Vol.40 No.3

Objectives: This study was conducted to explore awareness levels of myocardial infarction warning symptoms and related factors among residents in a province and we tried to present the evidence for education and promotion strategies. Methods: Study subjects were 594 adults live in a province. We surveyed demographic factors and awareness levels of myocardial infarction symptoms through telephone interview in 2013. The data were analyzed by using SAS 9.4. Results: In the survey, most frequently recognized warning symptoms were ``sudden chest pain and chest discomfort`` (75.1%), and ``sudden dyspnea`` (64.0%). However, ``sudden weakness and dizziness`` (45.1%), ``sudden pain in the jaw, neck or back`` (32.2%) and ``sudden discomfort in the upper limb or shoulder`` (31.3%) were less recognized. In a multiple regression analysis, male, no disease morbidity, no acquaintance history of myocardial infarction, low educational level, no exposure to promotional literature were significantly related to low awareness level of myocardial infarction warning symptoms. Conclusions: Providing customized programs will be helpful to enhance the efficiency of promotion and education to the population with low awareness level of myocardial infarction symptoms.

일개 광역시 도시 여성노인의 건강관련 삶의 질과 이에 미치는 요인

나윤주(Na, Yoon Joo),최연희(Choi, Youn-Hee) 한국산학기술학회 2014 한국산학기술학회논문지 Vol.15 No.12

본 연구는 일개 광역시 도시 여성노인의 건강관련 삶의 질과 이에 영향을 미치는 요인을 파악하고 요인들 간의 직간 접적인 관계를 파악하여 도시 여성노인의 삶의 질을 향상시키기 위한 중재안의 기초자료를 마련하고자 시행되었다. 2011년 지역사회건강조사 원자료 중 대구지역 7개구 65세 이상 여성노인 704명을 최종 분석하였다. 연령, 교육수준, 소득수준, 건강 증진행위, 사회적 지지, 신체적 건강, 정신적 건강을 변수로 포함하였으며 건강관련 삶의 질은 EQ-5D를 이용하여 측정하였 다. 건강관련 삶의 질 점수는 0.81(±0.20)로 나타났으며 영역별 문제는 통증/불편감(62.5%), 운동 능력(53.9%) 일상활동 (38.9%) 등의 순으로 나타났다. 건강관련 삶의 질은 연령, 신체적 건강, 정신적 건강, 사회적 지지, 건강증진행위, 소득수준에 의해 직접효과가 있었으며 이들 변수에 의하여 삶의 질을 28% 설명하였다. 건강증진행위, 사회적 지지, 소득수준, 연령은 건강관련 삶의 질에 직접효과 뿐 아니라 간접효과도 나타났다. 따라서 도시 여성노인의 삶의 질을 향상시키기 위하여 건강관 련 삶의 질에 직간접적으로 영향을 미치는 사회적 지지를 강화하고 건강증진행위를 증가시키는 포괄적인 프로그램의 개발이 필요하며 이는 삶의 질 향상에 도움을 줄 수 있을 것이다. This study attempted to identify the health-related quality of life and its related factors in urban elderly women. This study used the data of the 2011 Community Health Survey. The subjects of this study were 704 elderly women. Based on the literature review, this study examined variables with health-related quality of life and construct integrated conceptual framework of the study. For data analysis, SPSS 18.0 and LISREL 8.8. were used to calculate the percentage, mean, standard deviation, Spearman correlation, and path analysis parameter. The total mean EQ-5D index score was 0.81(±0.20) and the major problems were pain/discomfort (62.5%) and mobility (53.9%) and normal activity (38.9%). The model showed a goodness of fit to the empirical data. Age, income, health promotion behavior, social support, physical health and mental health had significant direct effects on EQ-5D and age, income, health promotion behavior and social support had indirect effects on EQ-5D. These variables explained 28% of the variance of EQ-5D. To improve the quality of life in urban elderly women, it is essential to have a comprehensive program for elderly women.

위장관 ; 위암에서 Helicobacter pylori CagA에 따른 RUNX3의 메틸화 및 발현의 소실과 임상병리학적 특성과의 관계

나윤주 ( Yoon Ju Na ),심기남(교신저자) ( Ki Nam Shim ),주양희 ( Yang Hee Joo ),김성은 ( Seong Eun Kim ),정혜경 ( Hye Kyung Jung ),정성애 ( Sung Ae Jung ),조민선 ( Min Sun Cho ) 대한소화기학회 2015 대한소화기학회지 Vol.66 No.2

Background/Aims: Helicobacter pylori cytotoxin-associated gene A (CagA) has been suggested to be involved in the inactivation of Runt-related transcription factor 3 (RUNX3), a known gastric carcinoma tumor suppressor gene. It remains unclear how H. pylori CagA initiates or maintains RUNX3 promoter methylation and inactivates its protein expression in gastric carcinoma. Methods: RUNX3 promoter methylation status, RUNX3 expression, and H. pylori CagA were investigated in 76 sample pairs of gastric carcinoma tissue. The patients’ medical records were reviewed. The association between RUNX3 methylation or loss of RUNX3 expression and clinicopathologic variables according to H. pylori CagA status were investigated. Results: In gastric carcinoma patients with H. pylori CagA-positive infection, RUNX3 methylation did not show association with lymphatic invasion, venous invasion, and TNM stages. However RUNX3 methylation was observed more frequently in poorly differentiated adenocarcinoma and signet ring cell carcinoma (77.8% vs. 20.0%, p=0.023) in early stage. In gastric carcinoma patients with H. pylori CagA-positive infection, loss of RUNX3 expression did not show association with lymphatic invasion, venous invasion, and TNM stages. However loss of RUNX3 expression was observed more frequently in early gastric carcinoma than in advanced gastric carcinoma (84.2% vs. 75.0%, p=0.51), but this difference was not significant. Conclusions: In gastric carcinoma patients with H. pylori CagA-positive infection, RUNX3 methylation or loss of RUNX3 expression did not show correlation with lymphovascular invasion and TNM stages. In early gastric carcinoma patients with H. pylori CagA-positive infection, RUNX3 methylation was observed more in poorly differentiated adenocarcinoma and signet ring cell carcinoma. (Korean J Gastroenterol 2015;66:75-84)

청소년의 COVID-19 예방행위에 영향을 미치는 요인

하영선,나윤주,Ha, Young-Sun,Na, Yoon-Joo 한국융합학회 2021 한국융합학회논문지 Vol.12 No.7

본 연구는 청소년을 대상으로 COVID-19 지식, 태도, 지각된 위험 및 예방행위의 수준을 파악하고 COVID-19 예방행위에 영향을 미치는 요인을 파악하고자 수행되었다. 서술적 조사연구이며, 연구 대상은 D 시, K 시 2개 고등학교학생 164명을 대상으로 2020년 10월 26일부터 11월 6일까지 자료수집을 시행하였다. 수집된 자료는 SPSS WIN 21.0 프로그램을 사용하여 t-test, one-way ANOVA, Pearson's correlation coefficient, multiple regression을 분석하였다. COVID-19 태도(β=0.28, p<.001)가 COVID-19 예방행위에 유의한 영향을 나타내었으며, 설명력은 9%이었다(F=3.849, p<.001). 교우관계 만족도(β=-0.05, p=.493), 경제 상태(β=-0.08, p=.270), 주관적 건강 상태(β=-0.06, p=.438), COVID-19 지식(β=0.04, p=.571), COVID-19 지각된 위험(β=0.05, p=.126)은 COVID-19 예방행위에 유의한 영향을 미치지 않았다. 청소년을 위한 COVID-19 예방행위를 높이기 위한 프로그램 개발 시 COVID-19 태도를 증진하려는 방안 마련이 필요하다. This study was aimed to investigate the factors influencing COVID-19 practice of COVID-19 knowledge, COVID-19 attitude, COVID-19 perceived risk among adolescents. A descriptive study design was used. Participants were 164 high school students in D and K city. The data were collected from October 26 to November 6 2020. Collected data were analyzed by t-test, one-way ANOVA, Pearson's correlation coefficient, multiple regression using SPSS WIN 21.0 program. Results: The influential factor for COVID-19 practice was COVID-19 attitude (β=0.28, p<.001). It was found that satisfaction with peer relationship (β=-0.05, p=.493), economic status (β=-0.08, p=.270), subjective health status (β=-0.06, p=.438), COVID-19 knowledge (β=0.04, p=.571), COVID-19 perceived risk (β=0.05, p=.126) had no significant effect on COVID-19 practice. In order to develop a program to increase the COVID-19 practice for youth, it is necessary to prepare a plan to improve the attitude of COVID-19.

통사-의미 역학의 신경언어학적 연구: L2 영어 학습자의 ``의문절 강요(question clause coercion)`` 구문 처리에 관한 ERP 기반 증거

박명관 ( Myung Kwan Park ),나윤주 ( Yoon Joo Na ) 한국외국어대학교 언어연구소 2013 언어와 언어학 Vol.0 No.58

This paper examined the brain responses to the question clause semantic coercion construction by Korean leaners of English. The construction at issue like The announcer guessed [the winner of the contest] is known to undergo semantic type shifting of the DP complement, which is understood as the clause like [who the winner of the contest was] rather than as it itself. We measured the neural responses by using the event-related potentials (ERP) paradigm and analyzed them in relation to the aspectual and complement semantic coercion constructions. It was found that the construction in question does not elicit N400 nor P600, unlike the other two constructions compared. We took it to show that question coercion has to be understood in the different ways from aspectual and complement coercion. In other words, for L2 learners the former type of coercion involves neither of semantic and syntactic shifts that the latter types of coercion allegedly do. In a nutshell, this study points to the finer-grained classification of different types of semantic coercion.

장중첩증으로 발현한 회장 말단의 외투 세포 림프종 1예

유금혜 ( Kum Hei Ryu ),심기남 ( Ki Nam Shim ),송현주 ( Hyun Joo Song ),나윤주 ( Yoon Ju Na ),백수정 ( Su Jung Baik ),윤수진 ( Su Jin Yoon ),정해선 ( Hae Sun Jung ),염혜정 ( Hye Jung Yeom ),정성애 ( Sung Ae Jung ),김태헌 ( Tae Hun 대한장연구학회 2006 Intestinal Research Vol.4 No.1

Although the gastrointestinal tract is one of the major sites of primary extranodal malignant lymphoma, the colon and small bowel are less frequently involved than the stomach. Mantle cell lymphoma comprising only 6% of the malignant non-Hodgkin lymphomas. Mantle cell lymphoma usually distributes from the esophagus to rectum, with advanced stages of peripheral lymphadenopathy, splenomegaly, and bone marrow infiltration. We report a case of ileocolic intussusception due to ileal mantle cell lymphoma. (Intestinal Research 2006;4:61-63)

미국 만성질환자가관리프로그램(CDSMP)의 성공 사례와 국내 적용가능성

안상남(SangNam Ahn),김건엽(Keon Yeop Kim),Marcia G. Ory,나윤주(Yoon Joo Na),김기수(Ki Su Kim) 한국보건교육건강증진학회 2014 보건교육건강증진학회지 Vol.31 No.4