청간소요산으로 호전된 설통 환자 3례

김연진,양승보,김정화,이상화,조승연,박성욱,박정미,고창남,Kim, Yeon-jin,Yang, Seung-bo,Kim, Jeong-hwa,Lee, Sang-hwa,Cho, Seung-yeon,Park, Seong-uk,Park, Jung-mi,Ko, Chang-nam 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.4

Objectives: This clinical study reports the effects of Cheonggansoyo-san (CSS) on three patients with glossodynia. Methods: Three patients with glossodynia were treated with CSS (i.e., an herbal medicine) and acupuncture. Numeric rating scales (NRSs) for glossodynia and dry mouth and hwa-byung questionnaire scores were evaluated, and the results from heart rate variability (HRV) evaluations were analyzed. Results: After treatment with CSS, three patients' glossodynia symptoms, such as burning sensations, tingling, and numbness of the tongue, were improved. NRS ratings for glossodynia and dry mouth and the hwa-byung questionnaire scores also improved, and HRV parameters were closer to the normal range. Conclusion: Cheonggansoyo-san could be used to treat glossodynia.

주변성 거대세포 육아종의 증례보고

정연화,조봉혜,나경수,김성수 大韓口腔顎顔面放射線學會 1997 Imaging Science in Dentistry Vol.27 No.2

The authors experienced one case of peripheral giant cell granuloma occurred at the gingiva of right maxillary molar in a 12-year-old male patient. The lesion showed amorphous calcification within soft tissue mass which made difficult to differentiate this lesion from peripheral ossifying fibroma and peripheral odontogenic fibroma clinically and radiographically. The final diagnosis was made histologically.

하악 비대칭의 방사선학적 연구

정연화,조봉혜 大韓口腔顎顔面 放射線學會 1998 Imaging Science in Dentistry Vol.28 No.1

The purpose of this study was to perform the radiographic measurements and temporomandibular joint evaluation in mandibular asymmetry. For this study, thirty-two patients who have mandibular asymmetry were selected and submentovertex, panoramic and lateral corrected tomographic radiographs were taken. Horizontal and vertical analysis using various landmarks on these radiographs were performed. Also radiographic and clinical evaluation of temporomandibular joint were obtained. The results were as follows; 1. On the submentovertex radiograph, the mean distance of Pogonion to midline was 5.0±3.8mm. 2. The mean distance of Pogonion to Gonion was 100.6±9.2mm in deviated side and 104.3±9.1mm in contra-lateral side, and there was a significant difference between the deviated and the contra-lateral side(p<0.001). 3. The distance difference of Pogonion to Gonion between the deviated and the contra-lateral side was significantly related to the degree of asymmetry(p<0.001). 4. On panoramic radiograph, the condylar height of the contra-lateral side was significantly longer than the one of the deviated side(p<0.001). 5. On lateral corrected tomogram, bony changes of temporomandibular joint were observed in 11 condyles of the deviated side and 9 condyles of the contra-lateral side. Erosion and osteophyte were the most common changes in both the deviated and the contra-lateral sides.

두경부 림프관종의 증례보고

정연화,조봉혜,나경수 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.1

Lymphangiomas are uncommon benign congenital tumors. Most occur in the head and neck and most lesions present by the age of 2 years. We present our experience with four patients who have iymphangiomas of the head and neck with tongue involvement. First case is a 7-year-old male who has the cystic iymphangioma of left submandibular area. Second a 22-year-old female has a lesion involving the border outright tongue. Third case is the iymphangioma which occurs in the right upper lip of a 6-year old male. The last patient is a 28-year old male who fell down and whose right face was swollen up. He had undergone an operation and been treated with steroid before. The characteristic appearances of imaging methods were described and all lesions best depicted on T2-weighted images. Our experience indicates that MRI is useful in the diagnosis and treatment planning of iymphangioma. (Korean J Oral Maxillofac Radiol 2000; 30: 87-91)

측두하악관절 내장 환자의 관절원판과 관절원판 후조직의 자기공명영상 신호강도

정연화,조봉혜 대한구강악안면방사선학회 2001 Imaging Science in Dentistry Vol.31 No.2

Purpose : To analyze the possible association between magnetic resonance imaging signal intensity of temporomandibular joint disk and posterior attachment, and the type and extent of disk displacement, disk configuration, effusion and clinical signs in patients with internal derangement. Materials and Methods : Magnetic resonance images of the 132 temporomandibular joints of 66 patients with temporomandibular joint displacement were analyzed. The clinical findings were obtained by retrospective review of the patients' records. The type and extent of disk displacement, disk configuration and effusion were evaluated on the proton density MR images. The signal intensity from the anterior band, posterior band and posterior attachment were measured on MR images. The associations between the type and extent of disk displacement, disk configuration, effusion and clinical signs and the MR signal intensity of disk and posterior attachment were statistically analyzed by student's t-test. Results : Of 132 joints, 87 (65.9%) showed anterior disk displacement with reduction (ADR) and 45 (34.1%) showed anterior disk displacement without reduction (ADnR). The signals from posterior attachments were lower in joints with ADnR than those of ADR (p〈 0.05). The results showed statistically significant (p〈 0.05) association between the type and extent of disk displacement and disk configuration, and decreased signal intensity of posterior attachment. There were no statistical associations between pain, noise and limited mouth opening, and signal intensity of disk and posterior attachment. Conclusions : The average signal from posterior attachment was lower in joints with ADnR than that of ADR. The type and extent of disk displacement and disk configuration appeared to be correlated with the signal intensity from posterior attachment. (Korean J Oral Maxillofac Radiol 2001;31:93-9)

동경파 유젠(東京派 友禪)에 관한 연구 : 수묘 유젠(手描友禪) 작가 중심으로

김호연,이정화 홍익대학교 산업디자인연구소 2006 미술디자인 논문집 Vol.- No.11

한국인에서 도파민 D4 수용체 다형성과 Novelty Seeking 성격 특성의 연관성

이헌정,이홍석,강화연,김린,이민수,서광윤,변영찬 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.4

연구목적 : 저자들은 한국인에서 도파민 D4 수용체(DRD4) 유전자의 다형성과 성격의 관련성을 알아보고자 본 연구를 시행하였다. 방 법 : 173명의 건강한 한국인 여자 청소년(13.88±0.29세)을 대상으로 하여 성격 기질 설문지(Temperament and Character Inventory : TCI)를 작성하도록 하였으며, 이들에서 DRD4 exon Ⅲ 48-bp VNTR(variable numbers of tandem repeats) 다형성을 분석하였다. 결 과 : DRD4 exon Ⅲ Vntr에서 긴 대립유전자(≥5 repeats)를 가진 군이 긴 대립유전자를 가지지 않은군에 비하여 Novelty Seeking 척도 점수가 유의하게 높았다(t=2.11,p=0.037). 결 론 : 본 연구 결과는 DRD4-exon Ⅲ의 긴 대립유전자가 Novelty Seeking 성격과 관련이 있다는 기존의 외국에서의 연구결과를 다시금 확인해주는 것이다. Objectives : We investigated the relationship of personality traits with dopamine D4 receptor(DRD4) exon Ⅲ polymorphism in a Korean population. Methods : We analysed DRD4 exon Ⅲ 48-bp repeats polymorphism in 173 Korean heakthy female adolescents(age=13.88±0.29years) who also completed Temperament and Charater Inventory(TCI). Results : Novelty seeking score of the TCI was significantly higher in the subjects with DRD4 long alleles(≥5 repeats) compares with the subjects without these (t=2.11, p=0.037). Conclusion : The present study supports the previous reports that long repeats of the DRD4-exon Ⅲ polymorphism are relatedwith Novelty Seeking personality.

인체 자궁암 세포에서 천연 성분이 P-당단백질의 활성에 미치는 영향

정수연,고은정,김나형,성민경,장정옥,이화정 이화여자대학교 약학연구소 2005 藥學硏究論文集 Vol.- No.15

Multidrug resistance (MDR) of cancer cells is, at least in part, associated with the overexpression of P-gly-coprotein (P-gp). Many studies hve demonstrated that natural compounds obtained from fruits, vegetables, teas and medicinal plants may modulate P-gp activity. The objective of the present investigation was to examine the effect of seven natural compounds on the P-gp activity in human uterine sarcoma cell line, MES-SA/DX5. Daunomycin uptake was significantly increased by biochanin A and silymarin (p<0.0001) whereas it was reduced by morin (p<0.01). The efflux of daunomycin from the cells was significantly inhibited by biochanin A, morin, cephalotaxine, berberine (p<0.05) and silymarin (p<0.0001). Biochanin A, berberine and silymarin significantly decreased IC_(50) value of daunomycin (p<0.05) while morin increased it (p<0.05). These results suggest that some natural compounds such as biochanin A and silymarin may inhibit P-gp funciton and can by developed as MDR reversing agents to improve the efficacy of chemotherapeutic drugs when administered concomitantly.

도시주부의 생활예절수행이 가족응집성 및 가정생활만족도에 미치는 영향

이정우,김연화 숙명여자대학교 출판부 2002 生活科學硏究誌 Vol.17 No.-

The purpose of this study was to explore the effect of performance of living proprieties on family cohesion and Family satisfaction, centering on house wives in the lives of Korean housewives. The results of this study were as follows: 1. The practice of life propriety was shown to be relatively high in house wives. The variables that affected this level were as follows: perceptiveness to the importance of propriety, self-esteem, perceptiveness to resource reasonableness. 2. Family cohesion and family satisfaction revealed a relatively high level. The variables affecting the family cohesion were self-esteem, perceptiveness to resource reasonableness, age, perceptiveness to the importance of propriety. The variables affecting the family satisfaction were self-esteem, perceptiveness to resource reasonableness, perceptiveness to health, gender-role attitudes, income, perceptiveness to the standard of living, fare orientedness. 3. The degree of the practice of life propriety significantly affected family cohesion and family satisfaction. 4. On the family satisfaction, the result showed the practice of life propriety were lower figures compared to the family cohesion. The important variables affecting the Family satisfaction were self-esteem, perceptiveness to resource resaonableness, perceptiveness to the importance of propriety, degree of the practice of life propriety. In addition, it was found that the most significant variable that influenced family satisfaction was family cohesion. Future research is needed to expand its focus on the practice of life propriety in the area of family resource management. More concrete and specialized family life education programs should be developed for the benefit of building healthy families.

하악과두의 인위적 병소에 대한 악관절 촬영법의 판독능 비교연구

조봉혜,정연화,정희정 大韓口腔顎顔面放射線學會 1997 Imaging Science in Dentistry Vol.27 No.2

The purpose of this study was to evaluate the detectability of various radiographic techniques for mandibular condylar lesions. Erowive lesion, osteophyte and flattening were formed on the artificial mandibular condyle, and panoramic, transcranial, transorbital radiography, lateral and frontal tomography were taken. The results were as follows; 1. The detectability for erosive lesions was superior in the order of frontal tomography(96%), lateral tomo-graphy (78%),transorbital(59%), transcranial(56%) and panoramic(48%)radiography. 2. The location of erosive lesion that showed the highest detectability was the medial third in panoramic, the lateral third in transcranial, the central portion of anteroposterior direction in transorbital, the central portion of mediolateral direction and the posterior third in lateral tomography. Frontal tomography disclosed all erosive lesions except one anterolateral lesion. 3. The detectability of osteophyte was 100% in lateral tomography, 78% in transcranial and 56% in panoramic radiography. 4. For flattening, lateral tomography showed the flattened condyle, but both panoramic and transcranial views showed only decreased bone density without the change of condylar shape.