Removal of aqueous vanadium(V) by green synthesized iron nanoparticles supported on corn straw biochar

Kun Rong,Xueping Li,Qian Yang,Ruimin Li,Zaiwang Zhang,Meiling Zou,Huanqiang Zheng,Juanjuan Liu 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.120 No.-

Iron nanoparticles supported on corn straw biochar (PE-FeNPs@BC) were used to remove V(V). This materialwas prepared by using Yali pear peel extract-supported iron nanoparticles (PE-FeNPs) as the functionalbody and corn straw biochar (BC) as the support. The synthesis conditions such as Fe/C massratio and synthesis temperature were optimized. The material was characterized by SEM-EDS, FTIR,XRD, and XPS. The results showed that particle agglomeration was reduced, and the dispersion wasimproved after PE-FeNPs were supported on BC. The removal effect was better in the pH range of 2–6,and the removal efficiency was the highest at pH 3.7. At 25 ℃ and pH 3.7, the maximum adsorptioncapacity qm of V(V) was 362.7 mg/g, and 95.1 % of 90 mg/L V(V) was removed. The coexisting NaCl orNaNO3 had a weaker effect on the removal of V(V). The adsorption reactions followed the pseudosecond-order model and Langmuir model, and chemical adsorption was the dominant process. The mainreaction mechanism of PE-FeNPs@BC with V(V) was as follows: adsorbed V5+ was reduced to V4+ by Fe0and Fe2+ and then removed by co-precipitation in the forms of xFe2O3yV2O5zH2O and VO2H2O. Thisstudy promotes the reuse of waste pear peel and can provide an environmentally friendly method forremoving V(V) pollution.

Physicochemical Properties and Antioxidant Activities of Melanin and Fractions from Auricularia auricula Fruiting Bodies

Yu Zou,Wenzhong Hu,Kun Ma,Mixia Tian 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.1

Fractions I and II from Auricularia auricula fruiting body (AAFB) melanin were separated using Sephadex G-100 column chromatography and their physicochemical properties and antioxidant activities were investigated. Molecular mass values of the fractions were 384 and 47 kDa, respectively. Fraction I exhibited lower L*, a*, and b* values than AAFB melanin and fraction II. AAFB melanin and fractions possessed the same solubility and spectroscopic properties, which were similar to the properties of other melanin. Elemental composition analysis revealed that the main component of AAFB melanin and fractions was pheomelanin. AAFB melanin and fractions, particularly fraction II, exhibited strong antioxidant activities based on Fe2+-chelating, DPPH radical scavenging, and superoxide radical scavenging activities.

Biomechanical Evaluation of 2 Endoscopic Spine Surgery Methods for Treating Lumbar Disc Herniation: A Finite Element Study

Yang Zou,Shuo Ji,Hui Wen Yang,Tao Ma,Yue Kun Fang,Zhi Cheng Wang,Miao Miao Liu,Ping Hui Zhou,Zheng Qi Bao,Chang Chun Zhang,Yu Chen Ye 대한척추신경외과학회 2024 Neurospine Vol.21 No.1

Objective: This study aimed to evaluate the effects of 2 endoscopic spine surgeries on the biomechanical properties of normal and osteoporotic spines. Methods: Based on computed tomography images of a healthy adult volunteer, 6 finite element models were created. After validating the normal intact model, a concentrated force of 400 N and a moment of 7.5 Nm were exerted on the upper surface of L3 to simulate 6 physiological activities of the spine. Five types of indices were used to assess the biomechanical properties of the 6 models, range of motion (ROM), maximum displacement value, intervertebral disc stress, maximum stress value, and articular protrusion stress, and by combining them with finite element stress cloud. Results: In normal and osteoporotic spines, there was no meaningful change in ROM or disc stress in the 2 surgical models for the 6 motion states. Model N1 (osteoporotic percutaneous transforaminal endoscopic discectomy model) showed a decrease in maximum displacement value of 20.28% in right lateral bending. Model M2 (unilateral biportal endoscopic model) increased maximum displacement values of 16.88% and 17.82% during left and right lateral bending, respectively. The maximum stress value of L4–5 increased by 11.72% for model M2 during left rotation. In addition, using the same surgical approach, ROM, maximum displacement values, disc stress, and maximum stress values were more significant in the osteoporotic model than in the normal model. Conclusion: In both normal and osteoporotic spines, both surgical approaches were less disruptive to the physiologic structure of the spine. Furthermore, using the same endoscopic spine surgery, normal spine biomechanical properties are superior to osteoporotic spines.

Synthesis, and antioxidant, thrombin-inhibitory, and anticancer activities of hydroxybenzamide derivatives

Jin-Rui Wei,Kun Liu,Faquan Lin,Chunping He,Xuan Luo,Jiajia Zou,Wei He,Wenqian Nong,Cui-Wu Lin 한국응용생명화학회 2016 Applied Biological Chemistry (Appl Biol Chem) Vol.59 No.2

Four hydroxybenzamide derivatives were synthesized from protocatechuic acid. The antioxidant activities of these derivatives were evaluated in vitro using DPPH radical scavenging and reducing power assays. In addition, these compounds were subjected to a chromogenic thrombin-inhibitory assay using Chromozym-TH as the substrate. The anticancer effects of these derivatives were also investigated using the MTT assay in three human cancer cell lines. Four derivatives exhibited excellent DPPH radical scavenging activity and redox potential. Their highly inhibitory effect against thrombin may allow them to be utilized as novel micromolecule thrombin inhibitors. Furthermore, four derivatives demonstrated different inhibitory activities in three human cancer cell lines but showed minimal harmful effects on normal HUVEC cells. Therefore, hydroxybenzamide derivatives indicate the superior antioxidant, thrombin-inhibitory, and anticancer activities along with the excellent biocompatibility, which have the potential application in therapeutic interventions and disease prevention of cancer, thrombotic diseases, and aging.

Luteolin Inhibits Proliferation Induced by IGF-1 Pathway Dependent ERα in Human Breast Cancer MCF-7 Cells

Wang, Li-Meng,Xie, Kun-Peng,Huo, Hong-Nan,Shang, Fei,Zou, Wei,Xie, Ming-Jie Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

The growth of many breast tumors is stimulated by IGF-1, which activates signal transduction pathways inducing cell proliferation. $ER{\alpha}$ is important in this process. The aim of the study was to investigate relationships in vitro among inhibitory effects of luteolin on the growth of MCF-7 cells, IGF-1 pathway and $ER{\alpha}$. Our results showed that luteolin could effectively block IGF-l-stimulated MCF-7 cell proliferation in a dose- and time-dependent manner and block cell cycle progression and induce apoptosis evidenced by the flow cytometric detection of sub-G1DNA content. Luteolin markedly decreased IGF-l-dependent IGF-IR and Akt phosphorylation without affecting Erk1/2 phosphorylation. Further experiments pointed out that $ER{\alpha}$ was directly involved in IGF-l induced cell growth inhibitory effects of luteolin, which significantly decreased $ER{\alpha}$ expression. Knockdown of $ER{\alpha}$ in MCF-7 cells by an $ER{\alpha}$-specific siRNA decreased the IGF-l induced cell growth inhibitory effects of luteolin. $ER{\alpha}$ is thus a possible target of luteolin. These findings indicate that the inhibitory effect of luteolin on the growth of MCF-7 cells is via inhibiting IGF-l mediated PI3K-Akt pathway dependent of $ER{\alpha}$ expression.

Influence of Driving Voltage on Starting Performance of High-Speed Permanent Magnet Synchronous Starter–Generator for Micro-gas Turbine

Qiu Hongbo,Wang Kun,Zou Xutian,Xiong Bin,Wu Xuanzong 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.6

The high-speed electrical machine as a critical power conversion unit in the micro gas turbine generation system needs to integrate the functions of starter and generator, which makes the control system of the machine more complex. In order to simplify the control system and improve the starting speed of the generation system with the help of the intrinsic starting ability of the machine, a high-speed starter–generator with multilayer composite solid rotor is proposed. The machine with the proposed solid rotor can realize self-start when it works in starting mode. Taking a 40 kW 20,000r/min high-speed permanent magnet machine as an example, the fi nite element model of the machine is established. The infl uence of driving voltage on the machine starting performance is analyzed and the start-up time, locked rotor parameters of the machine under diff erent driving voltages are further studied. Furthermore, in order to reveal the infl uence mechanism of driving voltage on the machine starting performance, the starting torque is decoupled and the infl uence of driving voltage on the decoupled torques is studied. Finally, the machine prototype is tested, and the correctness of the fi nite element model is verifi ed by comparing the experimental data with the fi nite element calculation data.

Emodin Inhibits Breast Cancer Cell Proliferation through the ERα-MAPK/Akt-Cyclin D1/Bcl-2 Signaling Pathway

Sui, Jia-Qi,Xie, Kun-Peng,Zou, Wei,Xie, Ming-Jie Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15

Background: The aim of the present study was to investigate the involvement of emodin on the growth of human breast cancer MCF-7 and MDA-MB-231 cells and the estrogen (E2) signal pathway in vitro. Materials and Methods: MTT assays were used to detect the effects of emodin on E2 induced proliferation of MCF-7 and MDA-MB-231 cells. Flow cytometry (FCM) was applied to determine the effect of emodin on E2-induced apoptosis of MCF-7 cells. Western blotting allowed detection of the effects of emodin on the expression of estrogen receptor ${\alpha}$, cyclin D1 and B-cell lymphoma-2 (Bcl-2), mitogen-activated protein kinases (MAPK) and phosphatidylinostiol 3-kinases (PI3K). Luciferase assays were emplyed to assess transcriptional activity of $ER{\alpha}$. Results: Emodin could inhibit E2-induced MCF-7 cell proliferation and anti-apoptosis effects, and arrest the cell cycle in G0/G1 phase, further blocking the effect of E2 on expression and transcriptional activity of $ER{\alpha}$. Moreover, Emodin influenced the ER ${\alpha}$ genomic pathway via downregulation of cyclin D1 and Bcl-2 protein expression, and influenced the non-genomic pathway via decreased PI3K/Akt protein expression. Conclusions: These findings indicate that emodin exerts inhibitory effects on MCF-7 cell proliferation via inhibiting both non-genomic and genomic pathways.

Effect of Bias Voltage on the Microstructure and Hardness of Ti-Si-N Films Deposited by Using High-power Impulse Magnetron Sputtering

JiCheng Ding,ChangWei Zou,QiMin Wang,Kun Zeng,SiCheng Feng 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.68 No.2

The huge potential of High-power impulse magnetron sputtering (HIPIMS) to improve the properties of deposited coatings has been verified. In this study, Ti-Si-N coatings were deposited on Si (111), glass and cemented carbide substrates by using HIPIMS. The influences of the peak voltage, duty cycle and total gas pressure on the transient peak current of the Ti90Si10 target was investigated in detailed. The (200) diffraction intensity decreased with increasing bias voltage from −50 V to −400 V. The hardness of the Ti-Si-N coatings deposited at various bias voltages and the internal stress at different bias voltages were studied. The results indicate that HIPIMS technology can considerably improve the mechanical capacity of the Ti-Si-N coatings, possibly due to the combined protection of the increased adhesive force with the substrate and the relatively high hardness, which are caused by densification and dislocation strengthening effects.

Research Articles : Off-Road Machinery System Engineering ; Road-friendliness of Fuzzy Hybrid Control Strategy Based on Hardware-in-the-Loop Simulations

( Tian Yi Yan ),( Qiang Li ),( Kun Ru Ren ),( Yu Lin Wang ),( Lu Zou Zhang ) 한국농업기계학회 2012 바이오시스템공학 Vol.37 No.3

Purpose: In order to improve road-friendliness of heavy vehicles, a fuzzy hybrid control strategy consisting of a hybrid control strategy and a fuzzy logic control module is proposed. The performance of the proposed strategy should be effectively evaluated using a hardware-in-the-loop (HIL) simulation model of a semi-active suspension system based on the fuzzy hybrid control strategy prior to real vehicle implementations. Methods: A hardware-in-the-loop (HIL) simulation system was synthesized by utilizing a self-developed electronic control unit (ECU), a PCI-1711 multi-functional data acquisition board as well as the previously developed quarter-car simulation model. Road-friendliness of a semi-active suspension system controlled by the proposed control strategy was simulated via the HIL system using Dynamic Load Coefficient (DLC) and Dynamic Load Stress Factor (DLSF) criteria. Results: Compared to a passive suspension, a semi-active suspension system based on the fuzzy hybrid control strategy reduced the DLC and DLSF values. Conclusions: The proposed control strategy of semi-active suspension systems can be employed to improve road-friendliness of road vehicles.

Heat Shock Factor 1 Is a Transcription Factor of Fas Gene

Shunmei E.,Yuanbo Zhao,Yunhong Huang,Kun Lai,Cha Chen,Jianming Zeng,Jiangying Zou 한국분자세포생물학회 2010 Molecules and cells Vol.29 No.5

In mammalian cells, stress-induced expression of heat shock protein is controlled by heat shock factor 1 (HSF1). However, HSF1 functions as a regulator of additional genes. In this study, we observed that heat treatment effectively induced expression of Fas. Using bioinformatics,a high affinity and functional HSF1-binding element within the -1996/-1985 oligonucleotide of the 5′-flanking region of the Fas gene was found, and was determined by electrophoretic mobility shift assay and chromatin immunoprecipitation assay. Exogenous expression of a constitutively activative HSF1, induced Fas gene transcription and protein synthesis in the absence of heat stress. Moreover, RNA interference-mediated HSF1 gene-silencing attenuated Fas expression in a heat-induced model. Our results suggested that HSF1 is an important transcription factor of Fas gene.