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최재석,서효주,이유리,권수정,문선화,박선미,손재학 한국식품영양과학회 2014 Preventive Nutrition and Food Science Vol.19 No.2
New in vitro anti-diabetes makgeolli was produced from rice by adding various quantities of Laminaria japonica,and the fermentation characteristics of the L. japonica makgeolli during the fermentation process were investigated. The contents of alcohol and reducing sugar, and viable count of yeast, of L. japonica makgeolli were not significantly changed when the proportion of L. japonica was increased. The total acid content decreased with an increase in L. japonica concentration; the pH and total bacterial cell count increased in proportion with the increase in L. japonica concentration. The L. japonica makgeolli contents of free sugars, such as fructose, glucose, and sucrose, and of organic acids, such as acetic acid, citric acid, succinic acid, and lactic acid, were altered during fermentation and showed various patterns. The effects of the quantity of L. japonica added on the acceptability and anti-diabetes activities of L. japonica makgeolli were also investigated. In a sensory evaluation, L. japonica makgeolli brewed by adding 2.5 or 5% L. japonica to the mash showed the best overall acceptability; the 12.5% L. japonica sample was least favored due to its seaweed flavor. L. japonica addition did not increase the peroxynitrite-scavenging activity of makgeolli. L. japonica makgeolli showed potent anti-diabetes activity, particularly that containing >7.5% L. japonica. Therefore, L. japonica makgeolli may represent a new functional makgeolli with anti-diabetes properties.
최재석,Choi, Jai-Sock 한국융합신호처리학회 2005 융합신호처리학회 논문지 (JISPS) Vol.6 No.3
전류모드 CMOS 회로기반 다치 논리 회로가 최근에 구현되고 있다. 본 논문에서는 4-치 Unary 다치 논리 함수를 전류모드 CMOS 논리 회로를 사용하여 합성하였다. 전류모드 CMOS(CMCL)회로의 덧셈은 각 전류 값들이 회로비용 없이 수행될 수 있고 또한 부의 논리 값은 전류흐름을 반대로 함으로써 쉽게 구현이 가능 하다. 이러한 CMCL 회로 설계과정은 논리적으로 조합된 기본 소자들을 사용하였다. 제안된 알고리듬을 적용한 결과 트랜지스터의 숫자를 고려하는 기존의 기법보다 더욱 적은 비용으로 구현할 수 있었다. 또한 비용-테이블 기법의 대안으로써 Unary 함수에 대해서 범용 UUPC(Universal Unary Programmable Circuit) 소자를 제안하였다. The implementation of Multiple-Valued Logic(MVL) based on Current-Mode CMOS Logic(CMCL) circuits has recently been achieved. In this paper, four-valued Unary Multiple-Valued logic functions are synthesized using current-mode CMOS logic circuits. We properly make use of the fact that the CMCL addition of logic values represented using discrete current values can be performed at no cost and that negative logic values are readily available via reversing the direction of current flow. A synthesis process for CMCL circuits is based upon a logically complete set of basic elements. Proposed algorithm results in less expensive realization than those achieved using existing techniques in terms of the number of transistors needed. As an alternative to the cost-table techniques Universal Unary Programmable Circuit (UUPC) for a unary function is also proposed.
최재석,김영욱,장수일 대한혈관외과학회 1993 Vascular Specialist International Vol.9 No.1
The aortoiliac segment is one of the common sites of chronic arterial occlusive disease which causes the ischemic symptom in legs and feet. Clinical manifestations range from intermittent claudication to gangrene, and it may lead to disability, amputation or even death. Proper management, therefore, of all arterial occlusive disease in lower limbs demands careful evaluation of the aortoiliac segment with recognition and correction of clinically significant lesion in the inflow vessels. Recently, authors had experienced 34 patients of chronic aortoiliac occlusive disease, who were admitted and treated at the Department of General Surgery, Kyungpook National University Hospital during the period from March 1989 to February 1992. The age of the patients ranged from 26 to 76 years with a mean age of 57.6 and men outnumbered women by 16: l. The associated disease in these patients were hypertension($gt;150/90 mmHg) in ll, coronary artery disease in 6, diabetes mellitus in 5, and cerebrovascular disease in 4 patients. Patient distribution, according to the types of the chronic aortoiliac occlusive disease, was 1 in Type I(3%), 8 in Type II(23.5%), and 25 in Type III(73.5%). Patient distribution, according to the grade of the ischemic symptoms, was 13(38.2%) in Grade I(with intermittent claudication), 6(17.6%) in Grade II(with rest pain), and 15(44.1%) in Grade III(with nonhealing ulcer or gangrene). In 28 out of 34 patients, we performed 25 primary and 2 secondary vascular operations for 25 patients and 3 iliac PTAs for 3 patients. Out of twenty five primary inflow procedures for chronic aortoiliac occlusive disease, 10 were aortobifemoral bypass, 3 were axillofemoral bypass, 9 were femorofemoral bypass, 2 were iliofemoral bypass, and 1 was iliofemoropopliteal sequential bypass. Two secondary inflow procedures were graft thrombectomy and axillofemoral bypass. The adjunctive outflow procedures performed with inflow procedures were 18 profundoplasties, 4 femoropopliteal bypasses, 1 distal embolectomy and I superficial femoral PTA. The adjunctive outflow procedure performed with iliac PTA was 1 femoropopliteal bypass. The early outcome of the treatment was estimated after one month according to $quot;Suggested Standards for Reports Dealing with Lower Extermity Ischemia$quot;. Our results revealed 25 limbs(64.1%) markedly improved, 12 limbs(30.8%) moderately improved, 1 limb(2.6%) minimally improved, and 1 limb(2.6%) markedly worse. Comparing these results among the 3 types of disease, there were no differences in their outcome. But we could find a better outcome in the Grade I patients(91.6% of markedly improved) and patients who underwent an aortobifemoral bypass(80% of markedly improved).