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순비기나무(Vitex rotundifolia) 줄기 추출물의 폴리페놀 함량과 생리활성
주은영,이양숙,김남우,Joo, Eun-Young,Lee, Yang-Suk,Kim, Nam-Woo 한국식품영양과학회 2007 한국식품영양과학회지 Vol.36 No.7
순비기나무(Vitex rotundifolia)의 줄기를 새로운 천연 항산화제나 생리활성 재료로 이용하기 위하여 한류 물 추출물(WE)과 에탄을 추출물(EE) 그리고 열수 추출물(HWE)에 대하여 총 폴리페놀 함량과 전자공여능, SOD 유사활성능, 아질산염 소거능 및 xanthine oxidase와 tyrosinase 저해 활성을 측정하였다. 총 폴리페놀의 함량을 측정한 결과 122.01 mg/g${\sim}$176.34 mg/g으로 EE에서 가장 많은 폴리페놀을 함유하였다. 전자공여능은 1.0 mg/mL의 농도에서 93.46${\sim}$96.92%로 EE가 가장 높았으며 0.1 mg/mL에서도 90% 이상이었으며, SOD 유사활성능은 WE가 47.32%로 가장 높은 활성을 나타내었다. 아질산염 소거능은 pH 1.2의 조건에서 세가지 추출물이 84.61${\sim}$88.36%였으며 pH 3.0에서는 25.83${\sim}$30.24%였다. Xanthine oxidase 저해 활성을 측정한 결과 0.5 mg/mL의 농도에서 세 가지 추출물 모두 90% 이상이었으며, 1.0 mg/mL에서도 91.02${\sim}$97.51%로 EE 추출물이 가장 높은 저해 활성을 나타내었다. 미백효과와 관련이 있는 tyrosinase 저해 활성을 측정한 결과 HWE와 WE는 57.84%와 53.47%를 나타내어 EE(28.79%)보다 높은 저해 효과가 나타났다. 따라서 순비기나무 줄기 추출물은 다량의 폴리페놀을 함유하며 항산화 활성과 xanthine oxidase 및 tyrosinase 저해 활성이 우수하므로 천연 항산화제나 미백 및 기능성 식품소재로써 활용할 수 있을 것으로 기대된다. For this study, extracts of Vitex rotundifolia stems were prepared using reflux water extraction (WE), reflux ethanol extraction (EE) and hot water extract under high pressure (HWE). The extracts were investigated for the total content of phenolic compounds, antioxidant activities, and inhibitory potencies for xanthine oxidase and tyrosinase. The EE extraction method yielded the highest content of polyphenol compounds (176.34 mg/g). The electron donating abilities (EDA) were 93.46${\sim}$96.92%, when extracts were assayed at 1.0 mg/mL. The superoxide dismutase (SOD)-like activity was the highest in the WE extract (47.32% at 1.0 mg/mL). The nitrite scavenging abilities (pH 1.2) were 84.61${\sim}$88.36% and the inhibition of xanthine oxidase were over 90% at 0.5 mg/mL. Tyrosinase inhibition of HWE and WE were 57.84% and 53.47% respectively. It implies that V. rotundifolia stems have potent physiological activities and their activities were differently exhibited depending on solvent fractions.
한국 Drosophila아속 (Diptera: Drosophilidae) 10종에 대한 계통학적 연구
주은영,이양숙,김남우 慶山大學校 基礎科學硏究所 2002 基礎科學 Vol.6 No.1
한국산 Drosophila아속 10종(D. virilis, D. tsigana, D. lacertosa, D. angularis, D. brachynephros D. curvispina, D. kuntzei, D. nigromaculata, D. takadai, D. unispina)을 대상으로 형태적 수리분석을 실시하여 계통관계를 알아보았다. 집괴분석과 분지분석으로 30종류의 형태적 형질을 분석한 결과 D. angularis와 D. brachynephros의 유연관계가 가장 높았으며, D. virilis와 D. takadai 사이가 가장 낮았다. D. quinaria종군은 0.7이상의 높은 유연관계를 보였다. 한편 D. virilis는 10종 중 원시형질을 가장 많이 보유하였으며, D. kuntzei 가 가장 늦게 분지된 것으로 분석되었다. 이상의 결과에서 한국산 Drosophila아속 10종은 D. virilis, D. tsigana, D. lacertosa의 group과 D. angularis, D. brachynephros D. curvispina, D. kuntzei, D. nigromaculata, D. takadai, D. unispina의 group으로 나눌 수 있으며, D. virilis가 속한 group이 더 primitive하다고 하겠다. 그러나 이 group이 다른 group의 직접적인 조상형은 아니며 다른 조상형이 있었을 것으로 생각된다. Phylogenic relationships among the 10 species (D. virilis, D. lacertosa, D. tsigana, D. angularis, D. brachynephros, D. curvispina, D. kuntzei, D. nigromaculata, D. takadai, D. unispina) of the subgenus Drosophila in Korea were investigated by taximetrical analysis. The taximetrical analyses of the 10 species according to the 30 morphological characters were performed using UPGMA and cladistic analysis. Two species D. angularis and D. brachynephros clustered at high similarity enough to suggest that they were closely related species and relatively high 0.8 have been found between quinaria species group. Also, D. virilis has the most primitive characters. These results might suggest that the subgenus Drosophila consist of two group; the 1st group of D. virilis, D. laoertosa, D. tsigana, and the 2nd group of D. angularis D. brachynephros, D. curvispina, D. kuntzei, D. nigromaculata, D. takadai and D. unispina. The group to which D. virilis belonged was considered as the primitive. However, it could not be the direct primitive to the another group. Instead it was presumed that there had been another ancestor.
석탄화력발전소 저온영역에서 조촉매 성분 및 함량에 따른 Metal type SCR 코팅 촉매 성능 연구
주은영,마동민,강다현,김미라,최동석,나우진,박해경 한국산학기술학회 2023 한국산학기술학회논문지 Vol.24 No.12
As NOx emission regulations are tightening, conventional SCR catalysts installed in coal-fired power plants cannot satisfy the regulations. In this study, NOx was reduced using a metal substrate catalyst with a high bulk surface area and high thermal responsiveness at low temperatures. The catalytic slurries were prepared with 14wt% V and different contents of Co, Ce, and W. The de-NOx performances of the prepared catalysts were investigated using a laboratory-scale atmospheric pressure reactor. The catalysts were characterized by air jet erosion, pressure drop test, Brunauer-Emmett-Teller surface area measurements, x-ray fluorescence spectroscopy, and scanning electron microscopy. At 180°C, the catalysts with Co and Ce exhibited lower de-NOx performance than those prepared with V alone. The catalyst with 8 wt. % W showed 4.6% higher de-NOx performance than the catalyst with V alone. A comparison of the pressure drop with the commercial honeycomb catalyst revealed the CPSI of the metal substrate to be twice as high, but the pressure drop was lower than the commercial honeycomb catalyst, and the de-NOx performance was better. Overall, the SCR catalyst coated on a metal substrate is a new type of catalyst that can be applied to various fields where the SCR process is applied.
주은영,이지은,강희숙,박신구,홍용희,신영림,손민 대한당뇨병학회 2018 Diabetes and Metabolism Journal Vol.42 No.6
Background: This study aimed to evaluate the relationship between the frequency of self-monitoring of blood glucose (SMBG) and glycosylated hemoglobin (HbA1c) levels among Korean adolescents with type 1 diabetes mellitus (T1DM). Factors affecting the SMBG frequency were analyzed in order to improve their glycemic control. Methods: Sixty-one adolescents aged 13 to 18 years with T1DM were included from one tertiary center. Clinical and biochemical variables were recorded. Factors associated with SMBG frequency were assessed using structured self-reported questionnaires. Results: Average total daily SMBG frequency was 3.8±2.1 and frequency during the school day was 1.3±1.2. The mean HbA1c level was 8.6%±1.4%. As the daily SMBG frequency increased, HbA1c levels declined (P=0.001). The adjusted odds of achieving the target HbA1c in participants who performed daily SMBG ≥5 significantly increased 9.87 folds (95% confidence interval [CI], 1.58 to 61.70) compared with those performed SMBG four times a day. In the subjects whose SMBG frequency <1/day during the school day, an 80% reduction in the adjusted odds ratio 0.2 (95% CI, 0.05 to 0.86) showed compared to the group with performing two SMBG measurements in the school setting. The number of SMBG testing performed at school was significantly high for individuals assisted by their friends (P=0.031) and for those who did SMBG in the classrooms (P=0.039). Conclusion: Higher SMBG frequency was significantly associated with lower HbA1c in Korean adolescents with T1DM. It would be necessary to establish the school environments that can facilitate adequate glycemic control, including frequent SMBG.